LOCUS       HEL45           4214966 bp    DNA     linear   CON 08-NOV-2006
DEFINITION  Oceanibulbus indolifex HEL-45.
ACCESSION   HEL45   
VERSION     HEL45.1
KEYWORDS    .
SOURCE      Oceanibulbus indolifex HEL-45
  ORGANISM  Oceanibulbus indolifex HEL-45
            Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
            Rhodobacteraceae; Oceanibulbus.
REFERENCE   1  (bases 1 to 4214966)
  AUTHORS   Wagner-Dobler,I., Ferriera,S., Johnson,J., Kravitz,S., Beeson,K.,
            Sutton,G., Rogers,Y.-H., Friedman,R., Frazier,M. and Venter,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2006) J Craig Venter Institute, 9704 Medical
            Center Drive, Rockville, MD 20850, USA
FEATURES             Location/Qualifiers
     source          1..4214966
                     /organism="Oceanibulbus indolifex HEL-45"
                     /mol_type="genomic DNA"
                     /strain="HEL-45"
                     /db_xref="taxon:391624"
     gene            complement(<1..90)
                     /locus_tag="OIHEL45_00005"
     CDS             complement(<1..90)
                     /locus_tag="OIHEL45_00005"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467006965_OIHEL45_00005"
                     /translation="MPELATFGYRFGTMGYGKFIKKSAPMMPAG"
     gene            214..561
                     /locus_tag="OIHEL45_00010"
     CDS             214..561
                     /locus_tag="OIHEL45_00010"
                     /note="COG2826 Transposase and inactivated derivatives,
                     IS30 family"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transposase for insertion sequence
                     element"
                     /protein_id="jcventer:1103467006965_OIHEL45_00010"
                     /db_xref="CDD:32654"
                     /translation="MEGLIDSLSPLPAEARRSITFDRGTEFTAWRHLKAGLGVDAWFC
                     DPKSPWQKGTVENTNNRLRRYLPRKADPTVFTDRYLRSICDRLNNTPRKCLGYQTPAE
                     VFRLNLMERVTSP"
     gene            794..1378
                     /locus_tag="OIHEL45_00015"
     CDS             794..1378
                     /locus_tag="OIHEL45_00015"
                     /note="COG0454 Histone acetyltransferase HPA2 and related
                     acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467006965_OIHEL45_00015"
                     /translation="MTLEAAEFLQAENERLNHELRAFVSVALQHGLQDYCETRHPVLT
                     ADIRSSQDKSQVGARKKYADVLARINQVPGLQGETGHTEDRTYYRNAQDNVAYIEHSF
                     RNRRFFLGGIWVAPHHREKGIAHTILRALVKASDAVDLSVELVHEPFGNEGLRMDDLE
                     AFYNRHGFTRQRTSDGGMVRFPRSSLDLYLGEPG"
     gene            <2050..2290
                     /locus_tag="OIHEL45_00020"
     CDS             <2050..2290
                     /locus_tag="OIHEL45_00020"
                     /note="COG1171 Threonine dehydratase"
                     /codon_start=2
                     /transl_table=11
                     /product="putative threonine dehydratase catabolic"
                     /protein_id="jcventer:1103467006980_OIHEL45_00020"
                     /db_xref="CDD:31364"
                     /translation="FPIMQRLAGPGLVVSDDEALQAMGHAFNRLKLVAEPGGAVALAA
                     ALFRGDEIEGDDVIVTISGGNVDSDMFARALQTLG"
     gene            2486..3289
                     /locus_tag="OIHEL45_00025"
     CDS             2486..3289
                     /locus_tag="OIHEL45_00025"
                     /note="COG0596 Predicted hydrolases or acyltransferases
                     (alpha/beta hydrolase superfamily)"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoadipate enol-lactonase, putative"
                     /protein_id="jcventer:1103467006980_OIHEL45_00025"
                     /db_xref="CDD:30941"
                     /translation="MQIFDTGEVQLHYRVDGPDDGAPVVFANSLGTDMRLWDPILSLL
                     APGLRIIRFDKRGHGLSSCPPAPYSMGSLITDTERLLDHLNVRDCVFVGLSIGGMIAQ
                     GLAVKRLDMIRALVLSNTATKIGNRDIWAERIAAVEQGGIESLADAVMERWFSAQFRA
                     TPELALWRNMLVRQPDAGYAGCSAAISHSDFMTPTSGLRLPALGIAGTEDGSTPPDLV
                     REMMDLIPASKFKLIRRAGHLPCVEQPQEYAETLNEFLVSVGHISKARG"
     gene            3379..3699
                     /locus_tag="OIHEL45_00030"
     CDS             3379..3699
                     /locus_tag="OIHEL45_00030"
                     /note="COG0015 Adenylosuccinate lyase"
                     /codon_start=1
                     /transl_table=11
                     /product="3-carboxy-cis,cis-muconate cycloisomerase,
                     putative"
                     /protein_id="jcventer:1103467006980_OIHEL45_00030"
                     /db_xref="CDD:28780"
                     /translation="MRAILLVTGALAKVQGVIPELSAPAIHRASLENRIEPKARAKAT
                     SHNGVSVPALIDRFRAELQAPKPAQYVPWGATSQYTIDTALVPHLRQAPADALAFATR
                     ADHI"
     gene            3704..4924
                     /locus_tag="OIHEL45_00035"
     CDS             3704..4924
                     /locus_tag="OIHEL45_00035"
                     /note="COG0477 Permeases of the major facilitator
                     superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance protein"
                     /protein_id="jcventer:1103467006980_OIHEL45_00035"
                     /db_xref="CDD:32643"
                     /translation="MPLPLIFILLTVMIDAMGVGLILPVMPDLIREVRGGGLSDAALW
                     GGVLATGFAAMQFLFGPVLGGLSDRFGRRPVLLLALVVMTLDYGVMALAGSIWLLLIG
                     RLVGGVTAATHATASAYMADISSTQDRAARFGLIGAAFGAGFVLGPLMGGILGEYGTR
                     APFWAAAVLAAGNAALGWAVLRETLPQTQRRAFDWRRANPLGALRALGRLPGIGRMLF
                     VYFIYHVGFAAYPAVWAYFGVERFGWSPTMIGLSLGLFGVQMALVQGALIGPVTRRLG
                     ARRTVILGHVFALAAFAALTLLTSGTWALIMTPLAALAGVIPPALQGIMSARVSADAQ
                     GELHGALSSSTALAMILSPLTMTAVFAYFTASEAPLYLPGAPFLLALVLTLGGLVIFA
                     SRPTPTSQADSRAS"
     gene            4996..6087
                     /locus_tag="OIHEL45_00040"
     CDS             4996..6087
                     /locus_tag="OIHEL45_00040"
                     /note="COG1062 Zn-dependent alcohol dehydrogenases, class
                     III"
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase, putative"
                     /protein_id="jcventer:1103467006980_OIHEL45_00040"
                     /db_xref="CDD:31262"
                     /translation="MQTIKAAVCHAFDSPLSVEDVLLRAPVSSEVEVTLDAVAICHSD
                     ISFADGAWGGSLPAVYGHEAAGRVSAVGPNVQGLAEGDSVVVTLIRACGSCPSCASGQ
                     PTICETPQDPEGPLQTADGGPLHQAMATGGFAEKVVVDRSQVVKISHDIPKEAACLIA
                     CGVITGVGAVVNAAELRAGQDVVVIGAGGVGLNAIQGARIAGARRIVAVDMTEEKLAI
                     AREFGATDTVLATDAKPWRAAVKAMGRGADAVIVTVGAIPAYETATRYLAAGGRVIMV
                     GMPHSGARASYEPVILAAMGQGMVGSKMGDVVIQRDIPWMVDLYLQGRLQLDSLISGR
                     WRLDQINEAIADTKTGAARRNVILFNQPD"
     gene            complement(6089..7366)
                     /locus_tag="OIHEL45_00045"
     CDS             complement(6089..7366)
                     /locus_tag="OIHEL45_00045"
                     /note="COG2379 Putative glycerate kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate reductase protein"
                     /protein_id="jcventer:1103467006980_OIHEL45_00045"
                     /db_xref="CDD:32526"
                     /translation="MSNLNSPKRQFLAELFHTAVAAADPRLILKDILPLPPKGRTVVI
                     GAGKGAAQLAQAFEALWPHPYEGVVVTRYGYGASCQRIQVLEAAHPVPDQAGVEAARA
                     LQGALQGLGPEDQVIALICGGGSSLLPAPPEGLTLEDLQALNSALLASGAPISVMNDI
                     RKQFSTVNGGRLAELAYPAQVVSLIVSDVPGDDPGAVASGPTVPGRRSAGDVLEEVAA
                     RGLELPQHCMTFLKDAAQRPSLDAPSNTRTDVIASAGQSLAAAAEAARARGVNAWVLS
                     DAIEGEARDVALVHAALARQAAQSGFPHRAPLVLLSGGEATVTLRHKGRGGRNSEFAL
                     SLALGLEGQAEIAALAADTDGIDGSEENAGAFVDGGTTRAMRAAGVDPRGALQRNDAY
                     GAFAAIDALFHTGPTGTNVNDFRAILIGDLPES"
     gene            complement(7420..8409)
                     /locus_tag="OIHEL45_00050"
     CDS             complement(7420..8409)
                     /locus_tag="OIHEL45_00050"
                     /note="COG0837 Glucokinase"
                     /codon_start=1
                     /transl_table=11
                     /product="Glucokinase"
                     /protein_id="jcventer:1103467006980_OIHEL45_00050"
                     /db_xref="CDD:31179"
                     /translation="MWFLVGDIGGTNLRLAAVDAAGAVISRSEHATDGRTALPEVCAD
                     FCAKMSSAPEGVAVAVAGVVVDGRVRMTNANRTISRGDLAKACKIAPAKVMLLNDFEA
                     AAWSLATLDPEKVTYLQGGPASQPGPRVIIGPGTGLGVGALVWQGARPVAVPGEGGHV
                     RLTPHSAEEVAYFEALIALWPEVQMGDTMAVEAEAILSGTGMPYWYRAISQARGEAAT
                     LGGAAAIFAAAKTGEDANACRAVGLMARYLAGVAGDLGLVIGARGGVFLTGGVAQQNA
                     WIFDAAFLAAFNAGGRHSRWREALPLGLCHDPDFGLLGARNCLFADRDHPLPD"
     gene            complement(8547..8765)
                     /locus_tag="OIHEL45_00055"
     CDS             complement(8547..8765)
                     /locus_tag="OIHEL45_00055"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467006980_OIHEL45_00055"
                     /translation="MSPPDTNLNKQESRHKWPLIGMAIVVIFGIGIIVFWTGEEVATA
                     PGTEEEVIVDDGTAIEGDSTTTVPVAPD"
     gene            <9037..9247
                     /locus_tag="OIHEL45_00070"
     CDS             <9037..9247
                     /locus_tag="OIHEL45_00070"
                     /note="COG1755 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007005_OIHEL45_00070"
                     /db_xref="CDD:44054"
                     /translation="IILEEPLVVRGPFKYLSHPNYMLVVAEIIVAPMVLGLVWVALVF
                     SLLNAAMLWVRIGVEHKALAPLRAG"
     gene            complement(9471..9827)
                     /locus_tag="OIHEL45_00065"
     CDS             complement(9471..9827)
                     /locus_tag="OIHEL45_00065"
                     /note="COG2916 DNA-binding protein H-NS"
                     /codon_start=1
                     /transl_table=11
                     /product="Histone-like protein of HNS family"
                     /protein_id="jcventer:1103467007005_OIHEL45_00065"
                     /db_xref="CDD:40894"
                     /translation="MFDKNELKALSRKELEKLLADVKKALSSVQARDQREAKKAATKA
                     AAEFGFSLNDITETAALVPKKRKTKAKAAKKQSKPVFFNPEDTNQTWTGKGRQPNWYR
                     EQIATGMDPEAMRIKN"
     gene            complement(9978..10355)
                     /locus_tag="OIHEL45_00060"
     CDS             complement(9978..10355)
                     /locus_tag="OIHEL45_00060"
                     /note="COG0784 FOG: CheY-like receiver"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator, LuxR family
                     protein"
                     /protein_id="jcventer:1103467007005_OIHEL45_00060"
                     /db_xref="CDD:32386"
                     /translation="MAKRILHVDDDPIILDIVRATFEKDDEVTVTSVKNAFDALASIQ
                     GLKPDLIIVDIAMPTMGGFEFILELRKISETATTPIIILSGRARSLGAYNPFQQMAVV
                     VLEKPMEPDRLRYEAKTLLARVE"
     gene            complement(<10917..11839)
                     /locus_tag="OIHEL45_00075"
     CDS             complement(<10917..11839)
                     /locus_tag="OIHEL45_00075"
                     /note="COG3424 Predicted naringenin-chalcone synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="probable chalcone synthase protein"
                     /protein_id="jcventer:1103467006987_OIHEL45_00075"
                     /db_xref="CDD:33230"
                     /translation="MSIYLHSLATALPPYCLNQSDVRDRAALIFRDRYPQFGRLSRTF
                     DTAGIDQRHSVVPMDWFSQDHGWADRNSAFMTGARQMFIDAAQGALIEAGWRGADVDC
                     VVTVCSTGIATPSLDAQALTEMGFREDIMRVPVFGLGCAGGVSGLSTAQTIAAGLPGA
                     KVLLVVVEACSLSFRADRLQKADIIATVLFGDGSAAACISDTPPTTGKTVTVSRGHQK
                     TWPDTLQIMGWNVDETGFGVVFDRSIPDFVKTEFAAATDSALKAANLNHAQIDRYVCH
                     PGGAKVVDAIEGALHLDQGSLDAERSTLRRAG"
     gene            complement(12317..12703)
                     /locus_tag="OIHEL45_00080"
     CDS             complement(12317..12703)
                     /locus_tag="OIHEL45_00080"
                     /note="COG4331 Predicted membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467006987_OIHEL45_00080"
                     /db_xref="CDD:34053"
                     /translation="MTALKQHNSKSLNHRLFAVTLFAKAVLGVLQLAMAAAIFAGAVD
                     RLPALTQWYFRTELAEDPNDFLATRAFSLVGVIPTSDLNFYTTYFLAHGGLHIAIVAA
                     LLYGAAWAHRAAVYVLWAFVIYQLFE"
     gene            complement(12700..>13085)
                     /locus_tag="OIHEL45_00085"
     CDS             complement(12700..>13085)
                     /locus_tag="OIHEL45_00085"
                     /note="COG0586 Uncharacterized membrane-associated
                     protein"
                     /codon_start=3
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="jcventer:1103467006987_OIHEL45_00085"
                     /db_xref="CDD:30931"
                     /translation="TLASEARLRRFIARHGRWLTISERDLDRSLAWFRRNGGMAVFLG
                     RMVPGVRTLISVPAGMTGMPLLPFLLYTGLGSLLWTAALTVSGYLLEAQFAKVETWIN
                     PVTNVLLLGLLALYVWRLLRPKAER"
     gene            complement(<14289..14490)
                     /locus_tag="OIHEL45_00090"
     CDS             complement(<14289..14490)
                     /locus_tag="OIHEL45_00090"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007006_OIHEL45_00090"
                     /translation="MNKTVFRTLLASATALVLIGGTEGQIFSIAGSGIRSLASPSQSQ
                     LFDNNRVHQLDVTLPFSVLAAGD"
     gene            complement(14658..14996)
                     /locus_tag="OIHEL45_00095"
     CDS             complement(14658..14996)
                     /locus_tag="OIHEL45_00095"
                     /note="COG3212 Predicted membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007006_OIHEL45_00095"
                     /db_xref="CDD:33025"
                     /translation="MKHMISLTAMIVAGTVATTGMALAETDDANEMAMFSEAQIDIQK
                     ALTVALDAMDGKIASIEFESEDGKAVYEAVAVAPDGAMTEILIDVNDGTVIAQGPYGD
                     DDDEEDDDND"
     gene            complement(15084..15512)
                     /locus_tag="OIHEL45_00100"
     CDS             complement(15084..15512)
                     /locus_tag="OIHEL45_00100"
                     /note="COG2246 Predicted membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA-like protein"
                     /protein_id="jcventer:1103467007006_OIHEL45_00100"
                     /db_xref="CDD:32427"
                     /translation="MWRQLLRFGMVGLLATFVHMMIGFLLIQSTWHPLLANLFAFTIA
                     FVVSFIGHLGFSFADQEVSASSALWKFALVALIGFAFNEVLLIMLLSEGDLSDTVSLW
                     ISTGSAAVLTFALSRLWAFRTPHKAGGPVDVDPSANLTNQ"
     gene            complement(15512..>15758)
                     /locus_tag="OIHEL45_00105"
     CDS             complement(15512..>15758)
                     /locus_tag="OIHEL45_00105"
                     /note="COG0463 Glycosyltransferases involved in cell wall
                     biogenesis"
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyl transferase, group 2 family protein"
                     /protein_id="jcventer:1103467007006_OIHEL45_00105"
                     /translation="VGMTIAACSILYALWIAVRTLIFGIDVPGWSTLVVAVMLLGGVQ
                     LISIGVLGEYLSRVFTEVKGRPGFIIAEDFSADSEHL"
     gene            complement(<15859..16367)
                     /locus_tag="OIHEL45_00110"
     CDS             complement(<15859..16367)
                     /locus_tag="OIHEL45_00110"
                     /codon_start=1
                     /transl_table=11
                     /product="Integrase, catalytic region"
                     /protein_id="jcventer:1103467007022_OIHEL45_00110"
                     /translation="MYSYEERLRAVKLYIKLGKRAQATIRELGYPTKNALKGWHREYQ
                     RLQDLPIRSAPRTPKFSTAQKQVALEHYATHGRCISWTLRALGYPGRATMTAWVREAF
                     PDTKTTSNATYGPGNHSDAVKQAAVVGLYSRQESAQALAKKFGVSRPTLYAWKTQILG
                     PEAPAMMKR"
     gene            complement(16549..16992)
                     /locus_tag="OIHEL45_00115"
     CDS             complement(16549..16992)
                     /locus_tag="OIHEL45_00115"
                     /note="COG1357 Uncharacterized low-complexity proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007022_OIHEL45_00115"
                     /db_xref="CDD:31548"
                     /translation="MKNLAFRTSRLGVLLTVALLFGTSATGQEPEQEKQLRMLGRCPG
                     CTFEQLDLTGRKLTGIDLTEAQLRDVDFSEAGLNLSLFDQATLENVSFDSADLTGASF
                     TGAKLINVSFENTVLKAAVFEDAILIDTDLTQGSIATRRCQMRPW"
     gene            complement(17020..17271)
                     /locus_tag="OIHEL45_00120"
     CDS             complement(17020..17271)
                     /locus_tag="OIHEL45_00120"
                     /note="COG3809 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007022_OIHEL45_00120"
                     /db_xref="CDD:33603"
                     /translation="MQCPIDGTQLVMTDRSGVEIDYCPQCRGVWLDRGELDKIIERSG
                     PEPAPRDVASLRSSGQDHGHGRPYKKKRREGFLSELFDF"
     gene            complement(<17425..17831)
                     /locus_tag="OIHEL45_00125"
     CDS             complement(<17425..17831)
                     /locus_tag="OIHEL45_00125"
                     /note="COG1846 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, MarR family protein"
                     /protein_id="jcventer:1103467007031_OIHEL45_00125"
                     /db_xref="CDD:47674"
                     /translation="MTDTPLTKAENAPLDQMGLDNFAPYLMNRIMGRYNAALSAEMAA
                     LGLTTPQMRSLAVLSVTDGILIRELAVYAVVQQSTLSRALDALVRDGLVRRETDAADS
                     RATRVYLTEKGGDAYARLWPHMAEAYGAMFKGI"
     gene            complement(17835..18608)
                     /locus_tag="OIHEL45_00130"
     CDS             complement(17835..18608)
                     /locus_tag="OIHEL45_00130"
                     /note="COG1878 Predicted metal-dependent hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007031_OIHEL45_00130"
                     /db_xref="CDD:32062"
                     /translation="MRDFGAMLASGGVEVVDCSGVLGPDTPILQLPADFAKPTPKVEI
                     HKISEYDEDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYEDGFTDTLDVQRLVAPVN
                     VIDCSQQSQEDPDFLLDAKGIKEWEAEYGEIGEGEWVVMRTDWDSHVNDEARFLNADE
                     TGPHSPGPTPDAIEYLMSKKIVGWGTQCIGTDAGQAGGMEPPYPAHNLLHKNNCFGLA
                     SLANLDKLPPKGAILIAAPLKIKNGTGSPIRALALVPKG"
     gene            complement(18802..19764)
                     /locus_tag="OIHEL45_00135"
     CDS             complement(18802..19764)
                     /locus_tag="OIHEL45_00135"
                     /note="COG0329 Dihydrodipicolinate
                     synthase/N-acetylneuraminate lyase"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxydipicolinate synthase"
                     /protein_id="jcventer:1103467007031_OIHEL45_00135"
                     /db_xref="CDD:30677"
                     /translation="MNPSIFSGCIPALMTPCTEDRKPDFDALVRMGKKLIADGMSAVV
                     YCGSMGDWPLLTDAERMEGVERLVNAGVPVVVGTGAVNTKLAAEHAAHAQKVGAKGLM
                     LIPRILSRGTSVAAQKDHFKAVLSAAPDLPAVIYNSPYYGFATRADLFFALRAEHSNL
                     VGFKEFGGADDLRYAAENITSRDDDVTLMIGVDTTVFHGFVNCGATGAITGIGNVLPR
                     EVLHLVALSQAAAAGDAEARQRAQELDAALGVLSSFDEGPDLVLYYKHLMVLEGHAEY
                     ALHFNETDALSDSQRGYAEAQYKLFRTWYADWSKQGGAVAKYAA"
     gene            complement(19896..20594)
                     /locus_tag="OIHEL45_00140"
     CDS             complement(19896..20594)
                     /locus_tag="OIHEL45_00140"
                     /note="COG1802 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulator protein"
                     /protein_id="jcventer:1103467007031_OIHEL45_00140"
                     /db_xref="CDD:31987"
                     /translation="MTSKPKSAERKRGSGAQFVYSILRDEILDLTLLPGSPIDEIRLS
                     ERLSMSRTPIREALVRLASEGLVTTLPNRSTVVSNIDFMNLHTFFDAMTLMYRVTTRL
                     AAQFHTPADMAAIRARQAEFAKAVEAQDALSMIATNREFHAEIARAGRNPYYESLCLR
                     LLDEGRRLLRMYYQSFDDQLPNEYAQEHEDLIATIEARDISRADSLAKTHADQIVRQI
                     QALISRDRRQHIDI"
     gene            20942..21949
                     /locus_tag="OIHEL45_00145"
     CDS             20942..21949
                     /locus_tag="OIHEL45_00145"
                     /note="COG0444 ABC-type dipeptide/oligopeptide/nickel
                     transport system, ATPase component"
                     /codon_start=1
                     /transl_table=11
                     /product="Oligopeptide/dipeptide ABC transporter,
                     ATP-binding protein, C-terminal"
                     /protein_id="jcventer:1103467007031_OIHEL45_00145"
                     /db_xref="CDD:30793"
                     /translation="MPNPDTGSDKVLLEVRDFSLRFRGLPSDQINHVNFSVSPGKTLC
                     VVGESGCGKSVTSLAMMGLLPAGAATIRSGEMIFEGQKLDLADHRAMRKLRGSRMTMI
                     FQEPMTSLNPAFRIGDQIAEAVLAHSDASKSEAEDKALAILKRVGIPAPEKRMRDYPH
                     QLSGGMRQRVMIAMALVNDPALLIADEPTTALDVTIQAQILELIRDLQAETDMGTIMI
                     THDLGVVAEIADTVAVMYAGTIVETGPAERIFNDPQHPYTIGLMSSIPQLSGPRGRLA
                     TVPGMVPTTQNMPEGCRFATRCPFAQPVCAKEPPLAPLEGGHAVACHFAPLETHLEQS
                     A"
     gene            21946..23055
                     /locus_tag="OIHEL45_00150"
     CDS             21946..23055
                     /locus_tag="OIHEL45_00150"
                     /note="COG4608 ABC-type oligopeptide transport system,
                     ATPase component"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein"
                     /protein_id="jcventer:1103467007031_OIHEL45_00150"
                     /db_xref="CDD:58285"
                     /translation="MSDHILKARALKKHFKTGGGMLAASGTVKAVDGVSFDVRRGETF
                     AIVGESGCGKSTLARLLMRLLTPTEGDVQFDGADVRSLAGRDLTALRRDMQFIFQDPF
                     SSLNPRMSVGKLVGEPLETHFPKMSAADRRGKVAELLAKVGLRPEHAERYPHEFSGGQ
                     RQRIGIARALASAPKLVIGDEPVSALDVSVQAQVINLLSDLRDELGLTLVIIAHDLAV
                     IRHMSDRVAVMYLGQIVEQGDVDTVYNHPRHPYTRALLSAIPVAAHGARTPQTALEGE
                     MPSPANPPSGCRFHTRCPYAKERCASEPPALREADAGNGHIAACHYFEEIAAATPDIG
                     LADVPERAPGAAARFALYEDAMRDRTTLRPRQDQQ"
     gene            23097..>23742
                     /locus_tag="OIHEL45_00155"
     CDS             23097..>23742
                     /locus_tag="OIHEL45_00155"
                     /note="COG0747 ABC-type dipeptide transport system,
                     periplasmic component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative solute-binding component of ABC
                     transporter"
                     /protein_id="jcventer:1103467007031_OIHEL45_00155"
                     /db_xref="CDD:31090"
                     /translation="MTLTKMTLAAALLGATTLGAQAADLRIALQSDADVLDPDQSRTF
                     VGRIVYTSLCDKLVDITPGLEIIPQLATEWSFSEDGKQLTMKLRDDAVFHDGTPFNAE
                     AVAANIDRSQNLETSRRKSELSSITGVEVLGSHEIRFDLADADATLMAQLADRAGMMV
                     SPTAAEAAGDDFGLAPVCSGPYQFKERVAQDRIVLEKFADYYNADEYHFDTVTYL"
     gene            complement(<23843..26032)
                     /locus_tag="OIHEL45_00160"
     CDS             complement(<23843..26032)
                     /locus_tag="OIHEL45_00160"
                     /note="COG0513 Superfamily II DNA and RNA helicases"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase, putative"
                     /protein_id="jcventer:1103467007051_OIHEL45_00160"
                     /db_xref="CDD:34219"
                     /translation="MAGNKRVVAVLAPTNTGKTTYAIERMLAHRTGVIGLPLRLLARE
                     VYDRIVKARGPSVVALVTGEERIVPPRTQYWVCTVEAMPQEMGADFVAIDEIQLCADP
                     ERGHVFTDRLLRARGLHETLFMGSDTMRGTIAALVPGVDFMRRDRMSELVYSGQKKIS
                     RMKPRSAIVGFSVENVYAIAELIRRQKGGAAVVMGALSPRTRNAQVEMYQNGEVDYLV
                     ATDAIGMGLNLDVDHVAFSALSKFDGRRMRPLAPNELAQIAGRAGRGFKSGTFGTTGD
                     APALDDGVARAIMDHNFTPQNKVNWRNHALQFGSIDRLIQTLEMPPEDERLVRARESD
                     DLKALKALAQVDEVFARATDGASVRLLWDVCRIPDFRGISHAEHAGLLETIFNDLHQR
                     GYIPDDWLARQIKRIDRTDGDIDALSKRLAFIRTWTYVAQRKGWTKDESHWRDTTRVV
                     EDRLSDALHERLTQRFVDRRTSVLLRRLGQKEAMVADVNETGEVTVEGEFVGKLDGFR
                     FRVDKGAGAAEDKTVKTAALQALAPQFHLRADRFYNAPDTEIDFTEQGGLMWGSAAVG
                     KLTAGSDALKPQVEVFVDDIAGPEVAEKVKRRLQHFIDRKIAALFEPLLALSKDETMT
                     GLARGFAFQLVENFGILPRAQVAEDVKSLDQDARGALRKHGIRFGQFTIFMPLMLKPA
                     PTRLRLVLWSLSKDLSEFPESPPPGLVTIPVEADAPAGADTMSGYRNA"
     gene            complement(26102..26602)
                     /locus_tag="OIHEL45_00165"
     CDS             complement(26102..26602)
                     /locus_tag="OIHEL45_00165"
                     /note="COG0457 FOG: TPR repeat"
                     /codon_start=1
                     /transl_table=11
                     /product="TPR-domain containing protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00165"
                     /db_xref="CDD:29151"
                     /translation="MRIIPVNLKHTVAAVGSFVLLAGMAVAEMAPPELMQKLRKAPAA
                     EAPRIAHEIEAYWQRSGSAAMDLLLARGREAMADGDPRQAIEHLTALTDHAPDFAEGF
                     HTRAQAYYGADLYGPALDDLERTLALNPDNYNAIFGLAVMLQEFGDLGRAGSCTQGAR
                     PQPASR"
     gene            26677..26967
                     /locus_tag="OIHEL45_00170"
     CDS             26677..26967
                     /locus_tag="OIHEL45_00170"
                     /note="COG3255 Putative sterol carrier protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00170"
                     /db_xref="CDD:42042"
                     /translation="MSDIVNEAVVVLNEKLAGSDFDGTAKFDIEGEGTVMMDENGARA
                     ADEEADVTLTADAETFQSILEGDTNPTSAFMTGKLKIDGDMGMAMKLAAVLG"
     gene            26967..27914
                     /locus_tag="OIHEL45_00175"
     CDS             26967..27914
                     /locus_tag="OIHEL45_00175"
                     /note="COG2267 Lysophospholipase"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase, putative"
                     /protein_id="jcventer:1103467007051_OIHEL45_00175"
                     /db_xref="CDD:32448"
                     /translation="MPLDPAPLFTDIAPGPEGGQAHWVETSDGKRIRLGHWPLAGARG
                     TVLLFPGRTEYIEKYGFCAAELARRGLATMAIDWRGQGLSDRMLPDARIGHVDAFSDY
                     QKDVAAMLRAARSLNMPRPYFLLAHSMGGCIGLRAVMEGLPVQAVAFTGPMWGIYVAP
                     RLRTLAWSLAQLMPRVGHGHRLPPGTRIEAYPAIAPFEDNLLTTDPQMYEMMRNQLAA
                     HPELSLGGPSFVWLREALTETKHLAGRAAPNIPCVTYLGSNERIVATNRVHARMAQWK
                     GGRLEIVEGGEHEVLLETPELRKPIFDGLEKLYLGNISG"
     gene            27977..28981
                     /locus_tag="OIHEL45_00180"
     CDS             27977..28981
                     /locus_tag="OIHEL45_00180"
                     /note="COG1236 Predicted exonuclease of the beta-lactamase
                     fold involved in RNA processing"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00180"
                     /db_xref="CDD:31429"
                     /translation="MTREPVLTFTENGIYCAAGDFYIDPWRPVDRALITHGHADHARD
                     GMGRYLATHAALPVMRHRLGEITAEGIAYGEQRIIGGATVSFHPAGHVPGSAQIRVEV
                     AGEVWVASGDYKVINDGMSEPFEPVKCHHFITESTFGLPVFRWAAQADVAADLNTWWA
                     ACAAAGKTAFLGAYSLGKAQRLLSMLDPDVGPILTHTAVENTNAVLRRQGITLPDTTL
                     VTPELAPKEHPGALVLAPPSALGSQWARRFGAQESAFASGWMALRGVRRRRAGDRGFV
                     ISDHADWPGLLWAIRETEAENIYVTHGYTDIFARYLNDQGWNAQVVPTQFDSDGGDSE
                     "
     gene            28978..30576
                     /locus_tag="OIHEL45_00185"
     CDS             28978..30576
                     /locus_tag="OIHEL45_00185"
                     /EC_number="6.5.1.1"
                     /note="COG1793 ATP-dependent DNA ligase"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA ligase"
                     /protein_id="jcventer:1103467007051_OIHEL45_00185"
                     /db_xref="CDD:31978"
                     /translation="MKDFAALFNAVDQTTKTTVKVAALAEYFTTAAEDDRLWTVALFS
                     GRRPKRAVTTTRLREWASEASGVPLWLFEDSYAIVGDLAETIALVLPPVDSDDTGTLT
                     SWINALRELKDEDDAARKAFVLSAWQQLGGTERFLFNKLITGSFRIGISQKLMTRALS
                     RATGKPEPEMAHRLMGNWHPDDVTWHSLIEAEDASADASRPYPFYLAYALEDGPEALG
                     DPTDWRAEWKWDGIRGQLILRDGDYFVWSRGEELMTDRFPELARAADHMPPGTVLDGE
                     LLVWQPGAEFPSSFNALQSRIGRKTVPKKLLKEAPVILHAYDLLEWQGEDIRARPFAE
                     RRALLEQASADLPEDAPIRLSPQHQFSDWSALADLRDTAREAQAEGLMLKRADSPYLS
                     GRKKGDWWKWKLDPLTIDAVMIYAQSGSGRRANLFTDFTFAVWNGNDLVPFTKAYSGL
                     TDAEFRSITAWVRKNTLQRFGPVRQVTPHHVFEIAFEGIQPSPRHKSGVALRFPRMLR
                     WRKDKPLQEANTLDDLKEMLRIYG"
     gene            30633..32450
                     /locus_tag="OIHEL45_00190"
     CDS             30633..32450
                     /locus_tag="OIHEL45_00190"
                     /note="COG1164 Oligoendopeptidase F"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F, putative"
                     /protein_id="jcventer:1103467007051_OIHEL45_00190"
                     /db_xref="CDD:31358"
                     /translation="MFQLPFPLYDANASAGGKDLGNLPEWDLSDLYTSEDAAELKRDL
                     DWLEEACASFAADYEGKLAELDAKGLLDCVLRNEKINQVAGRIMSYAGLRYYQQTTDS
                     GRAKFMSDMQEKITDYTTPLVFFTLELNKLPDDHLADLLNQDPDLARYKPVFDRIRAM
                     KPYQLSDEMEKFLHDLGVVGDAWERMFDETIAGLEFEVDGETLTIEGTLNLLTDPDRA
                     KREAGARELAEVLGANIRTFARVHNTQVKEKEVMDRWRGMETPQTGRHLSNHVEPEVV
                     EALRNAVVNAYPKLSHRYYELKRKWLGLDVMQVWDRNAPLPMEDPKVVNWAQAEETVM
                     EAYTAFDPRMGELAKPFFTDGWIDAGVKPGKAPGAFAHPTVTNVHPYVMLNYLGKPRD
                     VMTLAHELGHGVHQVLAADQGEMLSSTPLTLAETASVFGEMLTFRKMLDKAKTQAERK
                     VLLAGKVEDMINTVVRQIAFYDFECKLHEARRGGELTPDDINALWMSVQAESLGPAFE
                     YMDGYETFWAYIPHFVHSPFYVYAYAFGDGLVNALYAVYAAGEEGFEDKYFDMLKAGG
                     SKHHRELLAPFGLDASDPAFWDKGLSMISDMIDELEAME"
     gene            complement(32522..32791)
                     /locus_tag="OIHEL45_00195"
     CDS             complement(32522..32791)
                     /locus_tag="OIHEL45_00195"
                     /note="COG1734 DnaK suppressor protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00195"
                     /db_xref="CDD:31920"
                     /translation="MAGGWARDGAVSEQIEASISDELARMKARRAQVGESLTHCAECE
                     EPIPEARRIALPGVKLCIDCVRERDDQKQMRGGINRRGSKDSQLK"
     gene            32920..34095
                     /locus_tag="OIHEL45_00200"
     CDS             32920..34095
                     /locus_tag="OIHEL45_00200"
                     /note="COG2355 Zn-dependent dipeptidase, microsomal
                     dipeptidase homolog"
                     /codon_start=1
                     /transl_table=11
                     /product="renal dipeptidase family protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00200"
                     /db_xref="CDD:30044"
                     /translation="MRIIKIILAGLLAVVLLAVIGFFAFAPAFVEKSRNAVAVHDPYP
                     VSDAARALHDQLIVGDWHADPLLWNRDLSQRGDYGQVDVPRLIEGGVALQVFTAVTKS
                     PAGQNYDNNSADAFDNITALAVGQLWPFRTWNSLLERALYQAERLHKVEAALPDTFRI
                     IRTRADLDALLTDREAGSAVVGGILGIEGAHPLEGKLANLDLIEAAGHRVIGLHHFFD
                     NELGGSLHGQGNHGLSDFGRAVVAEVAKRGLVLDLAHSSPQVAQDVLEMTDIPLVVSH
                     TGVRAHCDVKRNFPDALMQEIAATGGVIGMGYWDEVACGDIRPAGIAKMIVKAVEVVG
                     IDHVSLGSDFDGSVATAFDTSEMPALTQTLMDAGLTETQIRKVMGGNMLRVLRARLK"
     gene            complement(34153..34539)
                     /locus_tag="OIHEL45_00205"
     CDS             complement(34153..34539)
                     /locus_tag="OIHEL45_00205"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00205"
                     /translation="MFISPIAQKSSAKIATLTAGDIIRRRRTYDPVLVSSPLDAHTLA
                     YKVIEARFLSVRYDRDFGKVEAMVEVTYSSHPSAPPRTVCLLTSVPSRGIGQRQEFRE
                     RLVQRAVSISVMFDRLNKGDTTLRAA"
     gene            complement(34758..35318)
                     /locus_tag="OIHEL45_00210"
     CDS             complement(34758..35318)
                     /locus_tag="OIHEL45_00210"
                     /note="COG2453 Predicted protein-tyrosine phosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="dual specificity protein phosphatase"
                     /protein_id="jcventer:1103467007051_OIHEL45_00210"
                     /db_xref="CDD:32569"
                     /translation="MLVDAPAFDPEFTSIRAVIPTPRGGYLAMTGFPGLLTHVDGTPY
                     LDPQQMTETLKGLRAVGARQFLVLTEEEELPNGAFSLISDISQQVGLEIHFAAIEDFN
                     VPGEAFLRRWPEHRARFEQALDAGEAVALSCQYGAGRSGLIAAWLLMGAGLPAATAVA
                     LVREHFHEAIENQLQENWLLDRDKVS"
     gene            35407..36039
                     /locus_tag="OIHEL45_00215"
     CDS             35407..36039
                     /locus_tag="OIHEL45_00215"
                     /note="COG1802 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, GntR family protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00215"
                     /db_xref="CDD:31987"
                     /translation="MLQQVKSSDMIAETLRADICLNRDIEDGMLHEVALAQRFGVSRT
                     PVRQALQRLAYERMIAVKSGVGSVITPLDGSKRADDICAAVAIIEAVAKCASAHAAPP
                     SQFMSVVGILGIMDISQLDRAEDFFETRAGLLTALAEMIENPILSDAFRAAYWRLIRW
                     TVRDHAAASGPQIDHLRELLQSAARAMKHGTLAEGFAQIATIEGRLCQPS"
     gene            complement(36101..36997)
                     /locus_tag="OIHEL45_00220"
     CDS             complement(36101..36997)
                     /locus_tag="OIHEL45_00220"
                     /note="COG0568 DNA-directed RNA polymerase, sigma subunit
                     (sigma70/sigma32)"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="jcventer:1103467007051_OIHEL45_00220"
                     /db_xref="CDD:30914"
                     /translation="MANYANLPAPTPEGGLNRYMQEIRKFPLLEPEEEYMLAKRWVEE
                     QDTEAAHRMVTSHLRLAAKIAMGYRGYGLPQAEVISEANVGLMQAVKRFDPEKGFRLA
                     TYAMWWIRASIQEYILRSWSLVKLGTTSGQKKLFFNLRKAKNKIGALEEGDLRPENVT
                     EIATQLGVTEAEVVSMNRRMSGGDASLNATVGSEGEGTMQWQDWLEDEDADQAGDYAE
                     RDELETRREMLADALDVLNDREKDILTQRRLSDETVTLEDLSTQYDVSRERIRQIEVR
                     AFEKLQKRMRDLAKDKGMMATT"
     gene            complement(37171..38217)
                     /locus_tag="OIHEL45_00225"
     CDS             complement(37171..38217)
                     /locus_tag="OIHEL45_00225"
                     /note="COG0564 Pseudouridylate synthases, 23S
                     RNA-specific"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal large subunit pseudouridine synthase
                     D"
                     /protein_id="jcventer:1103467007051_OIHEL45_00225"
                     /db_xref="CDD:30910"
                     /translation="MSHRRIDFILGDSPPARLDKALARDVPEAANLSRTRLGRLIEEG
                     AVTVDGAVVHDPRAKVAEGQVVQIKVEEAAESHILPEDIPLSVVFEDDDLIVIDKPAG
                     MVVHPAPGSPSGTLVNALLAHCGDDLSGVGGMKRPGIVHRIDKDTTGLLVVAKSDAAH
                     HGLAAQFEKHTVERYYQTLVYGVPDANDPRLRGVKGASFEAGNILRMTTQLARHKTDR
                     QRQAVLFQGGRHAVTRARTIERFGTPPVLALLECWLETGRTHQIRVHMSHAGHGLVGD
                     ATYGGRRKLAKTALPEATADAIRAFPRQALHAAVLGFEHPVTGENLRFEAPLPSDMAA
                     LLNLLRDGPVAPSA"
     gene            38216..38506
                     /locus_tag="OIHEL45_00230"
     CDS             38216..38506
                     /locus_tag="OIHEL45_00230"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00230"
                     /translation="MDTDNPDEPANLRFLRRMVTVLTVVMIGGVLVLIFVLVTRLSDQ
                     GPTMPRAITLPDGSSAQAFTQGRGWYAVVTDADTILIFDQLTGELRQTIPIE"
     gene            complement(38507..39292)
                     /locus_tag="OIHEL45_00235"
     CDS             complement(38507..39292)
                     /locus_tag="OIHEL45_00235"
                     /note="COG0483 Archaeal fructose-1,6-bisphosphatase and
                     related enzymes of inositol monophosphatase family"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase"
                     /protein_id="jcventer:1103467007051_OIHEL45_00235"
                     /db_xref="CDD:30137"
                     /translation="MIGSANLNIMIKAARKAGRALVKDFREVENLQVSVKGAGDFVTK
                     ADIGAEKIIKDDLMGARPTYGWLAEEGGEEEGQDPTRRWIVDPLDGTTNFLHGLPHWA
                     VSIALEHKGEIVAGVVFDPAKDEMFFAEKGTGAWMNESRMRVSGRHRMIESIFATGLP
                     FGGRADLPETLKDLGRLLPVCAGVRRWGAASLDLAYVASGRYDGFWERRLKPWDVAAG
                     MLIVKEAGGLVEAIRPERNILQHGEIICSNEPIYSTFAKTIRG"
     gene            39459..40499
                     /locus_tag="OIHEL45_00240"
     CDS             39459..40499
                     /locus_tag="OIHEL45_00240"
                     /note="COG2130 Putative NADP-dependent oxidoreductases"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase, L4bD family
                     protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00240"
                     /db_xref="CDD:32313"
                     /translation="MSDQMQKIVLASRPDGAPTPENFRLESADVPQPGNGEILVEVHY
                     MSLDPYMRGRMDDAKSYAEPVPIGGLMEGGSVGKVIASNDPSFQVGDFAFGAFGWATH
                     GVAPAKQCQKVDAEGVPITASLGVLGMPGLTGWYGLNEIGQPKEGETLVVAAATGPVG
                     SIVGQLAKAKGLRTVGIAGGAEKCEIATRDFGFDVCLDHRAYDDAKSLRAALKEAAPD
                     GIDIYYENVGGKVLDAVLPLMNPHGRIPLCGMIAWYNAGGLGADAEGAGLTAPRLWRT
                     ILVNFLTVRGFIISNHWNRMPEFHREVAPMVADGRVKVKEDITEGLENAPQAFIDMLN
                     GGNTGKAIVKVA"
     gene            complement(40614..41519)
                     /locus_tag="OIHEL45_00245"
     CDS             complement(40614..41519)
                     /locus_tag="OIHEL45_00245"
                     /note="COG0583 Transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator metR"
                     /protein_id="jcventer:1103467007051_OIHEL45_00245"
                     /db_xref="CDD:30928"
                     /translation="MHIEFRHLRTIKAIHEAGGLARAAEQMNITQSALSHQVKGLEDQ
                     AGVELFVRRSKPLKLSPAGQRLLKLAQQVLPQVEALQDEFSGLRAGSTGRMHIAIECH
                     ACFEWLFPVLEQFRRHWPDVDVDIRPGLAFDALPALLREEVDLVVSSDPEELPGVEFV
                     ELFDYNPVFVASQSHPLAAKPFVEAADFRGETLITYPVERSRLDVFSQLLIPAKVEPA
                     AIRQVELTAVILLLVASNRGVSVLPDWVVREVKYSSDYVTRPLTEKGITRRLYAAVRK
                     DDLGKPFMEELLKLAGQEARKLQRA"
     gene            41614..42480
                     /locus_tag="OIHEL45_00250"
     CDS             41614..42480
                     /locus_tag="OIHEL45_00250"
                     /note="COG0685 5,10-methylenetetrahydrofolate reductase"
                     /codon_start=1
                     /transl_table=11
                     /product="5,10-methylenetetrahydrofolate reductase"
                     /protein_id="jcventer:1103467007051_OIHEL45_00250"
                     /db_xref="CDD:29637"
                     /translation="MTTPAVSFEVFPPRTVGAAFKLWDAAQALAPLAPRFFSVTYGAG
                     GTTRDLTHDSAHVLHRTSGLPVAGHLTCVGASRAETMDVAEKFAEAGIKDIVALRGDP
                     QAGTDKFAPHPEGFADSCELIEALAKTGKFTIRVGAYPDPHPEAADQQANIDWLKRKF
                     DAGADEALTQFFFEADTFLRFRDACVKAGIDKPITPGILPVVNWTSARKFAVKCGTPI
                     PEWVDQAYEAAIRDDRHDLLAQALCTELCSDLIDEGVDALHFYTLNRAELTRDVCRAI
                     GVTPQVDLSDVA"
     gene            42561..43043
                     /locus_tag="OIHEL45_00255"
     CDS             42561..43043
                     /locus_tag="OIHEL45_00255"
                     /note="COG2050 Uncharacterized protein, possibly involved
                     in aromatic compounds catabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="Phenylacetic acid degradation-related protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00255"
                     /db_xref="CDD:48038"
                     /translation="MPRIAQSPADLLSQSDALNLSGLEFMQAILDGTNPGPPIGETMG
                     YTLHSVKDGQVVFRGAPSFAMTNPMGTVHGGWYGTLLDSAMACAIMTKVPRGSVYTTL
                     EYKINILRGLPIGMEIDCTGVIDHVGRSTGVAHGEIRGVDDGKLYATGSTTCIVMKLK
                     "
     gene            complement(43115..43570)
                     /locus_tag="OIHEL45_00260"
     CDS             complement(43115..43570)
                     /locus_tag="OIHEL45_00260"
                     /codon_start=1
                     /transl_table=11
                     /product="PRC-barrel"
                     /protein_id="jcventer:1103467007051_OIHEL45_00260"
                     /translation="MKNLTVSAVALTLAGTAAFAEAHMTDFSKVDSMAMSEMRGDLIR
                     TRDITGGEIYTVNEASDEWSPNTAYNGIDSGWNEIGEIEDIILSKDGQMVGIVAEVGG
                     FLDIGDKHVMISVPDVNLVAVDDTTYAYVTRLSEEELEALPSVDEGFWD"
     gene            complement(43738..43811)
                     /locus_tag="OIHEL45_t00452"
     tRNA            complement(43738..43811)
                     /locus_tag="OIHEL45_t00452"
                     /product="tRNA-His"
     gene            complement(43877..44062)
                     /locus_tag="OIHEL45_00265"
     CDS             complement(43877..44062)
                     /locus_tag="OIHEL45_00265"
                     /note="COG0454 Histone acetyltransferase HPA2 and related
                     acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase, GNAT family protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00265"
                     /translation="MLQTCMGFARDRGYEAMQLWTHESHRAAGRLYARNGWQLTGSRP
                     VISFGKANVEQTWEILV"
     gene            complement(44186..44359)
                     /locus_tag="OIHEL45_00270"
     CDS             complement(44186..44359)
                     /locus_tag="OIHEL45_00270"
                     /note="COG0454 Histone acetyltransferase HPA2 and related
                     acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase, GNAT family protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00270"
                     /translation="MENIEIRTFDPDDRDWLIAQHREHYCAKEGFDESFGVLVTQIID
                     DFIDGHDPNCERG"
     gene            44358..44627
                     /locus_tag="OIHEL45_00275"
     CDS             44358..44627
                     /locus_tag="OIHEL45_00275"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00275"
                     /translation="MPQHGRKIACLSTRAALAISPTKPEAHMGIDTERDIEANLQIGP
                     TDKGMVRLFVEGDGVEIPMDFTPDEAREIAEEIIAAASRAGKKGR"
     gene            complement(44654..45112)
                     /locus_tag="OIHEL45_00280"
     CDS             complement(44654..45112)
                     /locus_tag="OIHEL45_00280"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00280"
                     /db_xref="CDD:46209"
                     /translation="MMETDIKQFQPGQLLARGVMRHLADLGFACVEELVPTRGLRVDV
                     MALGPKGEVWIVECKSCRADFMGDAKWEGYLEWADRFFWAVDSDFPVDLLPEESGLII
                     GDAYGAEILRMSDETKLAPARRKVMVQKFATHAARRLHRLRDPDMAPNWS"
     gene            45220..46548
                     /locus_tag="OIHEL45_00285"
     CDS             45220..46548
                     /locus_tag="OIHEL45_00285"
                     /note="COG0840 Methyl-accepting chemotaxis protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00285"
                     /translation="MADREPMSETQARGVRYARELEGHLTWLDTFSGTALGVLAVASG
                     IYTYLGVSSLLDDNGAMSAFAAIAYSVAVSVGIFVFWSYLLRLFPAVRTTRARMGLLG
                     AMGLGSLAIIAMSSWLNAAALAGSAAVEQHLAKTVQDYQGALERSHEIALSAQGLERD
                     VARVRQSFEDLSEQEAAGSLSGLAGRGAVFRVLRQKSAELSGLEAQIATQTPLVNDAF
                     SEGNQILSRMRALTVEPGPVEARSVEFSEQAVRLAGLITRLRQLSVAPLVERAAQDLS
                     ASVVLPELDGSSEEQRGAQGATITSVLEVLAQRAATLERAAQDVQSMPPAADTTYTPI
                     SSADAVILYARNFVPSWAGAIAIDLLPAVLVMILAVTHGAIRSGREGAAVEDTLTLAE
                     LRAALAAVRDVDAAMQESPAHKRGAPAPQQPEETDRREDTPGHVTPIKST"
     gene            46545..47321
                     /locus_tag="OIHEL45_00290"
     CDS             46545..47321
                     /locus_tag="OIHEL45_00290"
                     /note="COG3904 Predicted periplasmic protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic protein-like"
                     /protein_id="jcventer:1103467007051_OIHEL45_00290"
                     /db_xref="CDD:33691"
                     /translation="MSESTPPDLGTTRKPPIVGRVLIGVLIFQLGLAVLLFWGDLGEG
                     LRLPGFGPQAPELTEPIRPGDQTRRFRPERAPNPGQPMPETALPDRLVLTPVSGGRAA
                     LLEGAIEAGDAERIVKQLSELTPAPEELYLNSPGGSVRDALELGRYLRREGFNTTLRD
                     GDICYSACPYLLAAGETRKVPDSASVGVHQHYFGKSTLLPAFVAVEDIQRGQGEVMRY
                     LDDMGIDPLVMQHALVTPPDEIYVLLPEELRRYGFIPEVE"
     gene            47416..47736
                     /locus_tag="OIHEL45_00295"
     CDS             47416..47736
                     /locus_tag="OIHEL45_00295"
                     /note="COG0640 Predicted transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, ArsR family protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00295"
                     /db_xref="CDD:47725"
                     /translation="MTDLSQPTFRALADPTRRDILKLLRHDDLTIAEVAGHFDMTRAA
                     VKKHLTVLSDGGLITVSARGREKVNRINPQGFAPVLSWIEYFDSFWDAHLDALKTAIE
                     KEKL"
     gene            47733..48155
                     /locus_tag="OIHEL45_00300"
     CDS             47733..48155
                     /locus_tag="OIHEL45_00300"
                     /note="COG3832 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00300"
                     /db_xref="CDD:45048"
                     /translation="MTNNTLRKTIFLQASRETVWQFLTQPDKIGTWFHAPTAPLKQGE
                     ELALYGNESGDRVVWGQVREARAPEYLEYSFTIKPMNGAESTVRWTLDKVPGGTRLSL
                     EHEGLPAGEAAFGLTLALDKGWDGHLGQLRDHLHENAA"
     gene            complement(48416..48892)
                     /locus_tag="OIHEL45_00305"
     CDS             complement(48416..48892)
                     /locus_tag="OIHEL45_00305"
                     /note="COG0781 Transcription termination factor"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="jcventer:1103467007051_OIHEL45_00305"
                     /db_xref="CDD:31124"
                     /translation="MTSNALSGNQKRKMKSASRLYAVQALFQMEHSAQTVDVVRHEFI
                     DHRFGAVYEGDEMQEGDVDHFSRVLEDAVNYQAPIDQMANRAIVAKWAIARIDPTLRA
                     LFRAAGAEFRHDETPPRVVIKEYVDVAHAFFPEGREPSFVNAVLDHMAREARPEAF"
     gene            complement(48889..49440)
                     /locus_tag="OIHEL45_00310"
     CDS             complement(48889..49440)
                     /locus_tag="OIHEL45_00310"
                     /note="COG0054 Riboflavin synthase beta-chain"
                     /codon_start=1
                     /transl_table=11
                     /product="Riboflavin synthase"
                     /protein_id="jcventer:1103467007051_OIHEL45_00310"
                     /db_xref="CDD:40962"
                     /translation="MASAEEHTILPRPEFDAPVKLLIVVSPYYSDIAHGMLTGAKAEL
                     EAAGADYEVVEMPGALEIPTAIGISDRGSNFDGYVALGCVIRGETTHYETVCNDSSRA
                     LQLLGLQGLCIGNGILTVENKKQAEVRADPEGQNKGGGAAAAALHLIALARKWGRQSK
                     GIGFKPFGQDTLMAGDTDGSNIA"
     gene            complement(49445..50569)
                     /locus_tag="OIHEL45_00315"
     CDS             complement(49445..50569)
                     /locus_tag="OIHEL45_00315"
                     /note="COG0108 3,4-dihydroxy-2-butanone 4-phosphate
                     synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone 4-phosphate synthase"
                     /protein_id="jcventer:1103467007051_OIHEL45_00315"
                     /db_xref="CDD:41001"
                     /translation="MQFDTPGPVETGLSDAISPIEEIIEDARQGRMFILVDHEDRENE
                     GDLVIPAQFADAAAINFMATHGRGLICLPMTSARIDHLGLPMMAVNNSSRHETAFTVS
                     IEAREGVSTGISAADRALTVAVAISEETGSADIATPGHVFPLRARDGGVLVRAGHTEA
                     AVDISRLAGLHPSGVICEIMKDDGEMARLPDLVEFAAEHGLKIGTISDLITYRHKHDN
                     LLVERDSRTVTSAYGGDWLMRVFSDQITGTDHVVLTKGDISTPEPVLIRTHAINALED
                     ILGLGPSPADELPHAMQIIADEGRGAVVLFRDPYPRLRLDAEDDDRPRTIKRTGLGAQ
                     ILSSMGLHELVLLTDNPDTRYLGLDAYALEIVGTRPITTE"
     gene            complement(50652..51239)
                     /locus_tag="OIHEL45_00320"
     CDS             complement(50652..51239)
                     /locus_tag="OIHEL45_00320"
                     /EC_number="2.5.1.9"
                     /note="COG0307 Riboflavin synthase alpha chain"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase subunit alpha"
                     /protein_id="jcventer:1103467007051_OIHEL45_00320"
                     /db_xref="CDD:30655"
                     /translation="MFTGIITDVGTVTKLEQEGDLRARIQTRYDTRGIDMGASIASDG
                     VCLTVVGLGDDWYEVQISAETVGKTNLGQHWAEGRRVNLERALKVGDELGGHIVSGHV
                     DGVAEIIEMKDEGDSTRVTLRAPKDLARFIAPKGSVALNGTSLTVNDVDGCDFGINFI
                     PHTKEVTTWGDAKVGDLVNLEIDTLARYVARLNEM"
     gene            51369..52661
                     /locus_tag="OIHEL45_00325"
     CDS             51369..52661
                     /locus_tag="OIHEL45_00325"
                     /note="COG3562 Capsule polysaccharide export protein"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide export protein KpsS"
                     /protein_id="jcventer:1103467007051_OIHEL45_00325"
                     /db_xref="CDD:45061"
                     /translation="MTVTADPTRTFLFLQGPHGPFFNSLGKMLRRAGAEVWRVGFNAG
                     DRAFWFHPSTYIPYRGTVEDWPQIFATLLDEKQVTDIVLYGDTRPIHAEAVAEAKRRG
                     ITVHVFEEGYMRPYWVTYERGGSNGNSRLMEMTIPQMQAALARSDMEAPLPPGHWGDM
                     RHHIFYGALYHWFVMFRNGDYRNFKPHRSLPVTKEFRLYLKRLLLMPVLAADRLLATL
                     KIRLGGFPYHLALLQLEHDSSFQQHSPFNTMADFLELVIEGFANGAPQHHHLVIKAHP
                     LEDGRAPVRRDVKRLARAHGVSDRVHFVRGGKLAQLLNDTRSAVTVNSTAGQQVLWRG
                     IPLKVFGRAVYSQPEFVSDQPLPEFFATASRPDNRAYKDYRRYLLETSQVPGGFYAAR
                     GRRQLLRQVVDMMLSAEDPYDALEQGTAAPRQQLRVVT"
     gene            52725..53909
                     /locus_tag="OIHEL45_00330"
     CDS             52725..53909
                     /locus_tag="OIHEL45_00330"
                     /note="COG1596 Periplasmic protein involved in
                     polysaccharide export"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00330"
                     /db_xref="CDD:42534"
                     /translation="MTIDDFEAENSGRGDRAVKSVSYRWARPIAALAALAVISSCGLP
                     QVGPNKRQIYAGSVQREGDAFVIAVNDRVTRAIAVAPALGFSESFKRAGQVGSDTIQP
                     GDILGITIYENVDDPLLGVEGAPATLLEEVQVDGAGFIFIPYAGRIRAAGNTPEAIRR
                     IITQKLGEQTPDPQVEVRRAAGDGSTVSLIGSIGAQGVYPIERPTRTLAAMLARAGGV
                     TIIPEIAQVTVIRNGQRGKIWFQDLYDHPELDIALRPGDRILVEEDTRSFTALGATGG
                     QARVPFESQNLSLLEGIAQVGGLSPISADPTGVFVFRNEPEEVAEQVLGRSDLTGAQR
                     MVYVTDLTKPNGMFMARDFVIRDGDTIYVTEAPFTQWSKVISAITGTASSADSISSLT
                     SG"
     gene            53919..55943
                     /locus_tag="OIHEL45_00335"
     CDS             53919..55943
                     /locus_tag="OIHEL45_00335"
                     /note="COG3563 Capsule polysaccharide export protein"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide export protein KpsC"
                     /protein_id="jcventer:1103467007051_OIHEL45_00335"
                     /db_xref="CDD:33365"
                     /translation="MAFEADPYQYPAAGPERSRRLFVYNGGFLTQRRLRRILQLSGHS
                     LRIGLPGPGDAVAVWGNSPTAHRGLAVAAKREVPVIRVEDAWLRSLHPGRAGEPPLGL
                     LIDSRGAHFDPAQPSDLEELLAHHPLDDTALLNRARGGMAQLAEHHLTKYAGFDLDMP
                     APDPGYVLVIDQTRGDASVTASGADRARFLEMLVLAQEEHPGARVIIKTHPETAQGFR
                     PGHFGPEDTNDRISLLSEPISPWTLFEGAVGVYTVSSQMGFEAIFAGHKPRVFGQPFY
                     AGWGLTVDEFPVQRRQRSLTRAQLFAAAMILYPTWYDPYRDTLCELETAVDALAAQAR
                     AWREDHHGWDAWGMRLWKRRPLQQFFGQSTPVRFRKGPPEAPAPPRRAMVWASKTEAA
                     PESALRVEDGFLRSRGLGAELVPPLSLVCDDLGIYYDPEGPSRLEKWIEKRADLRPDQ
                     HARARRLIETLTGAGLSKYNLGGAAPDLPTGRRILVPGQVEDDASILTGTDQVRTNAA
                     LLAAARAGNPDAVILYKPHPDVEAGLRTGATEAQDADVVLSHADPMALLGQVDAVWTM
                     TSLLGFEALLRGVQVVTLGAPFYAGWGLTEDHGDVPPRRRARVTLEGLVHAALIDYPR
                     YRDPVTGLPCPVEVVVERLSTGHIPRVGLGNRLLSKLQGVFASQSYLWRR"
     gene            complement(55947..57059)
                     /locus_tag="OIHEL45_00340"
     CDS             complement(55947..57059)
                     /locus_tag="OIHEL45_00340"
                     /note="COG0117 Pyrimidine deaminase"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein ribD"
                     /protein_id="jcventer:1103467007051_OIHEL45_00340"
                     /db_xref="CDD:32168"
                     /translation="MTGDKVSDARFMALALSLGRRGQGNVWPNPAVGCVIVQGTRIIG
                     RGWTHPGGRPHAEPQALAQAGEAARGATVYVTLEPCSHHGKTPPCAQALINAGVARVV
                     IATQDDDARVNGRGIAMLRAAGIDVSVGEREAEARADHAGFFCRTDLGRPMLTLKLAN
                     SFDGRIATGTGESQWITDAPARRLTHAMRARHDAVMVGAGTARKDDPSLTVRDLGVAH
                     QPARVVVSRRLDLPLMGQLARTAADIPLILCHGTDADPALVRTWSDLGATLLLCAARG
                     AQLDPTDVLRQLAGHGLTRIFCEGGSALAASLIEADLVDRLVGFTAGLVIGAEGLPGI
                     GALGLSRLAEAPRFALQSSQRIGPDLLHVWRRNAAD"
     gene            complement(57056..57523)
                     /locus_tag="OIHEL45_00345"
     CDS             complement(57056..57523)
                     /locus_tag="OIHEL45_00345"
                     /note="COG1327 Predicted transcriptional regulator,
                     consists of a Zn-ribbon and ATP-cone domains"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00345"
                     /db_xref="CDD:43403"
                     /translation="MRCPFCGNIDTQVKDSRPAEDHVSIRRRRFCPACGGRFTTYERV
                     QLRDLVVIKTSGKREDFDRDKLERSIRISMQKRPIDPERIDQMISGIVRRLESMGETD
                     ISSKHIGEIVMEALARIDTVAYVRFASVYKNFQAADDFDKFVQELRPGALPEE"
     gene            57709..58380
                     /locus_tag="OIHEL45_00350"
     CDS             57709..58380
                     /locus_tag="OIHEL45_00350"
                     /note="COG4221 Short-chain alcohol dehydrogenase of
                     unknown specificity"
                     /codon_start=1
                     /transl_table=11
                     /product="Short-chain alcohol dehydrogenase of unknown
                     specificity"
                     /protein_id="jcventer:1103467007051_OIHEL45_00350"
                     /db_xref="CDD:33946"
                     /translation="MTKTLFLTGASSGIGAATARAAAKAGWNIGLFARSEDKLKDLAT
                     ELGDQALVLVGDATDYDAQKAALDKLADHFGQVDAAFANAGRGTSPAGTENGDPQDWK
                     AMVDLNIMGALYTAHAAMPHLRKTTGQYVVTGSAAGRVHIQGSIYGATKWFIHGFAGN
                     LADEMAEWGGRCMVVSPGMVDTAFFDEAKPDKLQPEDVAAAVMHALESPARAAVREIH
                     LMPTG"
     gene            complement(58399..58815)
                     /locus_tag="OIHEL45_00355"
     CDS             complement(58399..58815)
                     /locus_tag="OIHEL45_00355"
                     /note="COG0432 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00355"
                     /db_xref="CDD:41914"
                     /translation="MQTCFSIRTGGQALYEFTEDVAAWVSGQGDGLLTLMIRHTSASL
                     LIQENADRDVQRDLLAYFSRLVPPSDSPQMSYLRHVMEGPDDMPAHIKASVLPVSLSI
                     PVAQGRMMLGTWQGIYLFEHRDAPHQRQVAAHFRPD"
     gene            complement(58816..59217)
                     /locus_tag="OIHEL45_00360"
     CDS             complement(58816..59217)
                     /locus_tag="OIHEL45_00360"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00360"
                     /translation="MKRNLCHRLLALALIAVPGMGQSVQPQRDLNITPVAGGFLVEND
                     SEHGARGMWCAAGRHAQTIGATSPKQRIYVAEARTPGLGQRNAVAFTLDPSGLATQPA
                     FLVGASFRQTGSSMSVQHALSICHALRGAGR"
     gene            complement(59221..59631)
                     /locus_tag="OIHEL45_00365"
     CDS             complement(59221..59631)
                     /locus_tag="OIHEL45_00365"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00365"
                     /translation="MRRFLVLLISCVLPLEAAAQAYRAENWLLVVPLNTFDFEVIEDR
                     GVGARGIWCAAGEFAQTVLALPVDERLYIKTPRGPSVSGVGRRGVVFTTDASRAEGDA
                     GQSYSVTVRRAGENLPSHHARQFCRDKLIELEDF"
     gene            complement(59776..61791)
                     /locus_tag="OIHEL45_00370"
     CDS             complement(59776..61791)
                     /locus_tag="OIHEL45_00370"
                     /note="COG0568 DNA-directed RNA polymerase, sigma subunit
                     (sigma70/sigma32)"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="jcventer:1103467007051_OIHEL45_00370"
                     /db_xref="CDD:30914"
                     /translation="MIRADALKEHEMAAKDTNDDAKTDDSDSGHSLDMSQAAVKKMIG
                     EAREKGYITYDQLNTVLPPDQVSSEQIEDVMSMLSEMGINIIEDEEAEEEEAKGSTEV
                     ATTESNRDVALSSGTSEKLDRTDDPVRMYLREMGSVELLSREGEIAIAKRIEAGRNTM
                     IAGLCESPLTFQAITIWRDELLSEDILLRDVIDLEATFGTQMGDEEETTPVVAPTATS
                     DTKSDEGKTELDADGHPISSDDDDDEDEQANMSLAAMEEALKPQVLEALDIIADDYEK
                     LSAMQDSRISATLNEDGSFTKDEEAMYQKLRSEIVLLVNELHLHNNRIEALIDQLYGI
                     NRRIMQIDSAMVKLADQARINRKEFVDNYRGYELDPNWMERMAEKSGRGWQMFIERSS
                     EKVDELRNDMAQVGQYVGLDISEFRRIVQQVQKGEKEARQAKKEMVEANLRLVISIAK
                     KYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
                     RIPVHMIETINKLVRTGRQMLHEIGREPTPEELAEKLQMPLEKVRKVMKIAKEPISLE
                     TPIGDEEDSQLGDFIEDKNAVLPLDSAIQENLKETTTRVLSSLTPREERVLRMRFGIG
                     MNTDHTLEEVGQQFSVTRERIRQIEAKALRKLKHPSRSRKLRSFLDQ"
     gene            59818..60843
                     /locus_tag="OIHEL45_00375"
     CDS             59818..60843
                     /locus_tag="OIHEL45_00375"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00375"
                     /translation="MLELAQRFGFDLTNTFTGDRELLADLFKRMVSVHADAKTHPQDT
                     FLTRGERRQHAGCGFLQVLLNGGIQRQHCVLVFDEVAKLAVFLVADWRLEADRLLGNL
                     HHLADLFERHLQLLGQFLGRWLTANLVQHLATGADQLIDRLNHVHRNTDGARLIGDRA
                     GDRLTDPPGRIGREFVAATVFELIHGLHQADVAFLNKIKELQTTVRVLFGDGDDETQV
                     RFDHLFLGLTGFFFALLNLLHDAAEFRDIKANVLTNLRHVVAQLIHFLGRAFDEHLPA
                     TTGFLGHPLHPIGIKLIAAVVVDEFLAVDARLVGKLHHGAVDLHDAAVDAVQLVNQGF
                     DTVVVQV"
     gene            complement(61895..63874)
                     /locus_tag="OIHEL45_00380"
     CDS             complement(61895..63874)
                     /locus_tag="OIHEL45_00380"
                     /note="COG0358 DNA primase (bacterial type)"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="jcventer:1103467007051_OIHEL45_00380"
                     /db_xref="CDD:30707"
                     /translation="MEELRDRASLSQVVGRKVIWDNRKSNQGKGDMWAPCPFHQEKSA
                     SFHVDDRKGFYYCFGCHAKGDAISFVRETENVSFMEAVEIIAREVGMPVPKQDPRAQA
                     KSDRRTQLAEVMEQAVQWFRLQLRTGAAGPARDYLAKRGLSEKAQAHWEIGFAPDNWQ
                     GLWDALKAKGVEDDLIFGAGLAKPSTKGGRPYDTFRGRIMFPIRDARGRAIAFGGRAM
                     DPNDKAKYLNSPETELFDKGRSLYNVKDARAAAGRGQPLIVAEGYMDVIALHGAGFEG
                     AVAPLGTAITENQLQMLWRIAPEPIITLDGDAAGQRAALRLIDLALPLLEAGQSLRFA
                     VMPEGQDPDDLLRAQGAGALQKLLDSALPMVKLLWQRETEGKVFDSPERKAALDKSLR
                     EKIKLIRDPSIRSHYGQEIKDLRWDLFRPQKPRADFRPVGGRGPGKGVGKGGKGGNWG
                     APLAPLASTKASALVAMSDDQVGLHLREAVILVALAGCPQLIETFETGLEGMACTDPD
                     HARLRDLLLRFGHASEEVLREEISYSLGWETLENIKAQRHVAITPCIRKPGNVEMTRM
                     TVAEELAKLDAARGLNEEIAEAVEDLSGPADEGVTWRLSEAARAADIARRSAQEDNNG
                     EFDVGDNGMTMSRDERSALDALLGTIRYDKSKGRG"
     gene            complement(64028..64336)
                     /locus_tag="OIHEL45_00385"
     CDS             complement(64028..64336)
                     /locus_tag="OIHEL45_00385"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00385"
                     /translation="MNKTILAALAAISMAVSGPALAASKKEESCMHQAAVVAAVQQAR
                     LNRVKEREVPATVQAKATWPEDFNTAIPLVTPWVYEMKMRDVKKSDLSAAWKEMCLAQ
                     "
     gene            complement(64388..64927)
                     /locus_tag="OIHEL45_00390"
     CDS             complement(64388..64927)
                     /locus_tag="OIHEL45_00390"
                     /note="COG4583 Sarcosine oxidase gamma subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="Sarcosine oxidase, gamma subunit"
                     /protein_id="jcventer:1103467007051_OIHEL45_00390"
                     /db_xref="CDD:34221"
                     /translation="MVELKAQSPFADLLPLKVGSMTVEERDLGRLTVLGGFASAAGLS
                     ETLEAAHGVTLPKPLQSTQKDNTRCLWFCQNEVLLVGPAPDETLANHAALVDVSDGWA
                     AAELQGPGAEDVLARLVPVDLRSATFKPGQTLRSQLREITASITRTDAGFLLLVYRSM
                     AGTLVQELRRAMEAVASRR"
     gene            complement(64920..67856)
                     /locus_tag="OIHEL45_00395"
     CDS             complement(64920..67856)
                     /locus_tag="OIHEL45_00395"
                     /note="COG0446 Uncharacterized NAD(FAD)-dependent
                     dehydrogenases"
                     /codon_start=1
                     /transl_table=11
                     /product="sarcosine oxidase, alpha subunit family protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00395"
                     /db_xref="CDD:30753"
                     /translation="MRIAGRGLIDRDKPVSFTFDGRRYDGFAGDTVASAMLANGQRLM
                     GRSFKYHRPRGVLSAGSEEPNALVTTGVGPASEPNVRATMQEIYEGLAVRSQNAWPSL
                     DFDVMAVNDLGAPFLGAGFYYKTFMWPRNFWRRVYEPVIRRAAGLGRLSGQPNADAYE
                     KAYAFCDLLVIGAGPAGLMAALTAARSGADVILADEDAPMGGRLNCESERIGGQPGHA
                     WAAGVVAELAAMDNVRLMPRTTVTGAYDGGMFGALERVNQHRARRGEGAPLECFWRIA
                     AKQSILAAGALERPVAFANNDRPGIMTAGAVRAYLNRWGVAPGKQVAVFGNNDDAHRT
                     ARDLAAAGVHVAALIDSRDRVSVDGADFPVLSGAVVCNASGRRELEAVTIRTAGGEHK
                     IQVDCLAMSGGWNPSVHLTCHLSGRPMWDPAIHAFVPTPGAVPGMHVAGACNGVFSTH
                     GCLAAGVAAAKGALEALGRKAEAIDLPPAEDAPYTLKPLWSVPGKGRAWLDFQNDVCV
                     KDVQQAAAENFRSVEHMKRYTTQGMAPDQGKSSNVAALAVLADATGRGIAETGTTTFR
                     PPYTPVAIAAMGAGGQGKGFAPERLTTSHAASLAMNAPMVEAGLWYRPSYFPRGREHN
                     WRQSCDREVGFVRKSVGICDVSTLGKIDIQGADAAKLLDLVYTNTFNTLKVGKVRYGL
                     MMREDGFVMDDGTCARLGEQHFLMTTTTGAAGQVMRHLEFVTQCLHPEWQVHLTSVTE
                     HWAQFAVAGPKSRELLNGLLEQPIDNDRFPFMACGDVRLGGVDARLFRISFSGEHAYE
                     VAVPARFGAALFDLLVARADALGGGAYGMEALNVLRLEKGHITHAEIDGRATASDIGM
                     ERMVSDAKDCIGKTMSERAGLRDPERAQLVGLRPVGAVKQLTAGAFLFETGAEASREN
                     AQGHTTSVGFSPDVGTFIGLGFVTRGRQRHGEVMRMVDHLREIEAEVEICAPVFVDPE
                     GGRARG"
     gene            complement(67853..68125)
                     /locus_tag="OIHEL45_00400"
     CDS             complement(67853..68125)
                     /locus_tag="OIHEL45_00400"
                     /note="COG4311 Sarcosine oxidase delta subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="sarcosine oxidase, delta subunit"
                     /protein_id="jcventer:1103467007051_OIHEL45_00400"
                     /db_xref="CDD:44180"
                     /translation="MRIECPICGSRDRREFYYRGAAVALARPAPDAGDDIWDAFLHLR
                     DNPAGETRDLWQHEAGCGAWLVVTRNTVTHAVHAVALASDVKRATL"
     gene            complement(68138..69391)
                     /locus_tag="OIHEL45_00405"
     CDS             complement(68138..69391)
                     /locus_tag="OIHEL45_00405"
                     /note="COG0665 Glycine/D-amino acid oxidases
                     (deaminating)"
                     /codon_start=1
                     /transl_table=11
                     /product="sarcosine oxidase, beta subunit"
                     /protein_id="jcventer:1103467007051_OIHEL45_00405"
                     /db_xref="CDD:31009"
                     /translation="MRFSGLRVLREGLTGNRRWTPQWGDPEPQAEYDAIIIGGGGHGL
                     STAYYLAKNHGMTNIAVLEKGYLGGGNVGRNTTVVRGNYFLPGNSEFYSHSLKLWEGL
                     SQELNYNVMFSQRGVITLFHSDAQRDAAARRGNAMINQGDDAELLDRNALRKLLPYLN
                     YDNGRFPIHGGLLHRRGGTARHDAVAWGYARGADQRGVDLIQQCEVTGIDIENGQVRG
                     VQTTRGAIRAKKVAIVTAGRSGQVAAMAGIRLPIESHVLQAFVTEGLKPVIDHVVSFG
                     MGHFYISQSDKGGLVFGGDLDFYASYAQRGNMPMMEHVMEAGMTLMPMIGKSRVLRSW
                     GGIMDMTPDGSPIIDKTDTEGLFIDCGWCYGGFKAVPASGFALAHLMATGQHHETAAG
                     FRLDRFRSGEGLMDEEATGSQHNLH"
     gene            complement(69541..70971)
                     /locus_tag="OIHEL45_00410"
     CDS             complement(69541..70971)
                     /locus_tag="OIHEL45_00410"
                     /note="COG0334 Glutamate dehydrogenase/leucine
                     dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate dehydrogenase"
                     /protein_id="jcventer:1103467007051_OIHEL45_00410"
                     /db_xref="CDD:30682"
                     /translation="MNPANEPSFRDSVDLMFNRAVALMDLPPGLEEKIRVCNATYTVR
                     FGVRLRGRIHTFTGYRSVHSEHMEPVKGGIRYSMAVNQNEVEALAALMTYKCALVDAP
                     FGGSKGGLCIDPRDYDEHELELITRRFAYELIKRDMINPAQNVPAPDMGTGEREMAWI
                     ADQYKRMNTTDINGVACVTGKPINAGGIQGRTEATGRGVQYALQAFFRDPEGLKKAGL
                     SGKLEGKRVIIQGLGNVGYHAAKFLSEEDGSKITAIIERDGALHSEDGLNVEAVHKWI
                     EKHGTIKGYADAKFEEDGAQFLEAECDILIPAALEGVINLSNAERIQAPLIVEAANGP
                     VTAGADEVLRKKGTVIMPDMYANAGGVTVSYFEWVKNLSHIRFGRMQRRAEESRHQLV
                     VDELERLSADKELGWTLSPNFKEKYLRGAGELELVRSGLDDTMRTAYEAMAHVWHSRD
                     DVEDLRTAAYLVSIEKVAASYHAKGL"
     gene            71328..72758
                     /locus_tag="OIHEL45_00415"
     CDS             71328..72758
                     /locus_tag="OIHEL45_00415"
                     /note="COG1841 Ribosomal protein L30/L7E"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00415"
                     /translation="MTNDPRTSETLAGCCPAMLRRFAREEDGLVTLFAILMILLMILL
                     GGVGVDLMRHERERARVQAVADRAVLAAADLDQTLSPEAVARDYFDKSGLADYISSVT
                     VEEGLNYRRVTVDASRDLKTMFIDKFGQEKLHVPAKATAEEKVAKVEISMVLDISGSM
                     RENDKMNNLHDASNVFIDTVIQTDTEDLISISVVPYTAQVNVGKDIMDELNVTQLHSY
                     SHCVDFEDSDFNLTTISQTRSYEHMQHFEAGYYWNGNDRDRTGHYDNISNPGCPKQSY
                     EEIETFSQNAAALKSRIANFQPRANTAIHLGLKWGVALLDPSFRAINEAIGGDAVFRG
                     RPAEYNDIDTLKTVILMTDGVNVTTRRIAPEAYSNRDHYRHWSDYPFYWWLGRNVRSS
                     EHYRWYRTKYTAGQADNLLDNICDAAKAKGIVIWSIGFEVTDHGAAVMKNCASSDSHF
                     FRVEGVEIVDAFEAIARQINQLRLTQ"
     gene            72755..73294
                     /locus_tag="OIHEL45_00420"
     CDS             72755..73294
                     /locus_tag="OIHEL45_00420"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00420"
                     /db_xref="CDD:34568"
                     /translation="MIQKTIKAWRRFRGDENGSVMLIEFAILSPLLFGCLIMSVEMSF
                     YAMRHMFLDRGLDMTVRYVRLNTNTDMSHQTIKNMICETAGYLQDCDETLRLEMIRVD
                     PRNFASFDPSPDCVDTSIDPKPVRGWSLGVEHQLMMLRACVQFKPFFPTTGLGYALEK
                     DGAGRVSMVSSAAFVQEPN"
     gene            73294..73842
                     /locus_tag="OIHEL45_00425"
     CDS             73294..73842
                     /locus_tag="OIHEL45_00425"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00425"
                     /db_xref="CDD:34568"
                     /translation="MRVLSSLLTRFKRSDDGSIAIETVIMLPLMFWAYLAMYSTFDTF
                     RMYNLNQTAAYTIGDAISRETQAIDPDYLQGMQELFEYLTRGTGQTSLRVSSLWYDAE
                     NDRYHADWSQIRGNVAPLTSDEVSNWHSKLPVMPDNERITLVETWRDFEPLFKTGLER
                     REIRNFVFTRPRYAPRTVWSDT"
     gene            complement(73839..74345)
                     /locus_tag="OIHEL45_00430"
     CDS             complement(73839..74345)
                     /locus_tag="OIHEL45_00430"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00430"
                     /translation="MTDIPQTMQPGVGDVLATAKASPARRGVGLLALAGLGVVLIYSA
                     LTRSPDLGWQIALAAIGLGFIAIAELMRRSTASALELTDDALRDADGRVIVRMDEIER
                     IEQGAFAVKPSNGFLLKTNRRVPRGWRLGLWWSLGRRIGVGGMTPANETKLIAEMIRA
                     KLAERDAA"
     gene            complement(74466..74987)
                     /locus_tag="OIHEL45_00435"
     CDS             complement(74466..74987)
                     /locus_tag="OIHEL45_00435"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00435"
                     /translation="MTKGPSPRRGRLLQLALGVSLAVNVMILGALGGAMWRHGGAGPR
                     GDGDLPGLRSYASPYVQALPPEARRSLHETMRASGKAHHLDRAKRRGLYERMLTTLRA
                     DPFDTEAAAAVLAAQGEAAATVQEVAHSAWLAQISAMDAASRVAYADKLQERFETGRQ
                     RKKDKREGSPERK"
     gene            complement(74989..75357)
                     /locus_tag="OIHEL45_00440"
     CDS             complement(74989..75357)
                     /locus_tag="OIHEL45_00440"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007051_OIHEL45_00440"
                     /translation="MNDFDDDALEDFFAAARANPPRVTADLQARILADAEALMPKSNL
                     LKLPWHRALWQLFGGAAGLSGLATAAAVGIWVGVAPPDGMPDLAGQFVSGTWDVETVD
                     TAEVDTEIEFGGFGWDMEES"
     gene            complement(75350..75946)
                     /locus_tag="OIHEL45_00445"
     CDS             complement(75350..75946)
                     /locus_tag="OIHEL45_00445"
                     /note="COG1595 DNA-directed RNA polymerase specialized
                     sigma subunit, sigma24 homolog"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="jcventer:1103467007051_OIHEL45_00445"
                     /db_xref="CDD:31783"
                     /translation="MDGMQNLSDDQRDADAELLQRYATGDAAAARLLTTRLVPRIHGH
                     ALRVLGDRAEAEDVAQEAMLRLWRQAPEWRTGEAKVTTWVYRVVANLCTDRLRRRGAG
                     AAGLDDVAEPADPTPGVTQKMQQAAREDALQQALATLPERQRQAVVLRHIDGMANPEI
                     AEVLGIGVEAVESLTARGKRALAAQLSAQRDALGFDDE"
     gene            complement(<75969..76641)
                     /locus_tag="OIHEL45_00452"
     CDS             complement(<75969..76641)
                     /locus_tag="OIHEL45_00452"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00452"
                     /translation="MMFRARLIAHPVADNGALLEVEGITLTSAALDSPIALPALDNQV
                     IKAAAPQSLPPAPDSHSTAITAACDITAEAEAVAAAMVKLTLDAACLPNERLTVHHNG
                     MIFTEVTDDKGQLNVTVPALAEEAVFILAFGNGDGAVAQTSVSELSGFNRIVLQWKGA
                     AGFELHAREFGADYGDAGHVWSGAPRDMTAAVLGERGFMTRNGDTDTSDPLMAEVYSF
                     PVAAAG"
     gene            complement(76642..77268)
                     /locus_tag="OIHEL45_00457"
     CDS             complement(76642..77268)
                     /locus_tag="OIHEL45_00457"
                     /note="COG5126 Ca2+-binding protein (EF-Hand superfamily)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00457"
                     /translation="MTIRTNMKIAALSGLLALGGAAAFAQQSGGQNPFQQLDADGNGE
                     ITQAEFQAHAEARFAKVDADGDGFVTAEEMKAAGEARHAERAAKMLERFDTDGNGSLD
                     ASELEAMGGKHGEMRGDKRGDKDGSKKDGKRGHKGGERMIERMDTNDDGKLSMEEMTQ
                     RHDPAKMFERLDKDDNGSISAEEFEAAKMHGKRHGKGHKMDHDKPQRD"
     gene            77487..77903
                     /locus_tag="OIHEL45_00462"
     CDS             77487..77903
                     /locus_tag="OIHEL45_00462"
                     /note="COG1405 Transcription initiation factor TFIIIB,
                     Brf1 subunit/Transcription initiation factor TFIIB"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00462"
                     /translation="MSQTQQLSPDTVDAHDSEERARLPAMLRGWRGKCPSCGGGQLLH
                     GYLKVNDDCAACRQEFHHHRADDGPAYLTILLVGHLLAPGLHIAFVVWRPEPLTLFTI
                     FAVGCTALSLYLLPRLKGAMIGFQWAKRMGGFGGTT"
     gene            77946..78641
                     /locus_tag="OIHEL45_00467"
     CDS             77946..78641
                     /locus_tag="OIHEL45_00467"
                     /note="COG0494 NTP pyrophosphohydrolases including
                     oxidative damage repair enzymes"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase, NUDIX family protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00467"
                     /db_xref="CDD:40389"
                     /translation="MTIDKTQIRNAATVIVLRDRHVTPHILMGQRGAKAAFMPNKFVF
                     PGGAVDASDARVPLAAPVNALCHGRLCDDAEPSLAHAIAVAAIRELWEETGLVLGRKG
                     GWEGDVPADWNSFAATGHLPDASALQFVFRALTPPGRPRRFDARFFLVDAEDIASDPD
                     DFDAACDELSHLQWVPLSRARSFDMPFITEVVLAEITARARDTNPPASVPFFKNNDEE
                     SLFLRLHGRPMTG"
     gene            complement(78638..79558)
                     /locus_tag="OIHEL45_00472"
     CDS             complement(78638..79558)
                     /locus_tag="OIHEL45_00472"
                     /note="COG0697 Permeases of the drug/metabolite
                     transporter (DMT) superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00472"
                     /translation="MDSIFTPDLWILVTLAAAVFQTGRFMLQKHLASDMLSAGGATFS
                     RFLYSAPFVALLLPLYLGLSGQGLPVLGPGFWLYGVMGGTAQIMATVCVVLLFKQRNF
                     AVGITFKKTEVIQTVLMGWIVLGEGVSGAGFAAIALGVVGLLLLSGGAEAKGLRLADL
                     RNRAAGLGIASGFLFAISAVCYRGASLAVVSDDPLLRAGVTLAAVVLMQTLIMAVWLR
                     LREPGQMRRVWAARRVAVWIGLTSMGGSLCWFIAFTLQNAAYVKALGQVELMLSIAAS
                     TLFFREHISRREWAGMAVLALSIMMLVLVT"
     gene            complement(79606..80151)
                     /locus_tag="OIHEL45_00477"
     CDS             complement(79606..80151)
                     /locus_tag="OIHEL45_00477"
                     /note="COG3040 Bacterial lipocalin"
                     /codon_start=1
                     /transl_table=11
                     /product="Lipocalin-like protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00477"
                     /db_xref="CDD:32854"
                     /translation="MGRLIPWVRRASVLLLLATLAACNRSEPPPVQTGFRNADALIGA
                     TSRYDAARFGGDWQVRAAFPGDANLRAVTFAPQGPTLIETRGACDAAGVCTDRRDLWA
                     LNEQGPGRYTMRAAVGGAERAFWVLWVDEGFRTAVVGSPEGGYGWILDRQATGGEDRI
                     TAAQEILDFNGYDISALQVRR"
     gene            complement(80151..81194)
                     /locus_tag="OIHEL45_00482"
     CDS             complement(80151..81194)
                     /locus_tag="OIHEL45_00482"
                     /note="COG0667 Predicted oxidoreductases (related to
                     aryl-alcohol dehydrogenases)"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase, putative"
                     /protein_id="jcventer:1103467007065_OIHEL45_00482"
                     /db_xref="CDD:31011"
                     /translation="MKMKKLGSSDIEVSRFCLGSMTWGTQNTAEEGHAQIDRALEAGI
                     NFIDTAEMYPVNPISAETIGRTEEIIGQWVARDKRRDEVVLASKHSGEGMQHARDGAP
                     ISSDTIPGAIEGSLKRLQTDYIDLYQFHWPNRGSYMFRKNWTFDPSGQNRAETIAHME
                     DALGALQREVERGTIRAFGLSNESAWGLTQWAAVAERTGGPRPISVQNEYSLMCRLAD
                     TDVSETCVNEQIDMLAFSPLAAGLLTGKYQGGKVPAGSRLSLNEDLGGRITPRAFEAV
                     AAYLDVAEKHGLDPVQMALAWCDTRPFMGSVIFGATSLEQLDVALGGADLTLSDEVMA
                     DLDAVHKTHPMPY"
     gene            81298..82572
                     /locus_tag="OIHEL45_00487"
     CDS             81298..82572
                     /locus_tag="OIHEL45_00487"
                     /note="COG0477 Permeases of the major facilitator
                     superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator superfamily transporter,
                     putative"
                     /protein_id="jcventer:1103467007065_OIHEL45_00487"
                     /translation="MGAFSLPLARQWTQCALMRLLISFAALFFSVILLQLSTGGVGPL
                     DVLSGLQLDFSRQEIGMLGSAHFLGFFIGCWWAPRLMGSVGHSRAFAAFTAAGAIGLM
                     AHMMVVDPYAWALMRVASGMCVAGCYTVIEAWMQAKVTNETRGRTMGVYRVVDMSGSL
                     AAQLIVGILAPAAYVSYNLLAIICCAALLPLTLTKVRPPETPNQPRLRPRLAFDRSPL
                     AAAGVVVAAVSSASFRMVGPIYGQEVGLSATQIAWFLAAFVLGGALAQYPMGMLADKY
                     DRRWVLIWLSVAAMGGCAVTVMGAGYGTAGIMLSAGLFGATTFPIYSVSAAHAHDFAS
                     SDERVELSAALMFFFAVGAIGAPYLASVLIDGFGASALFVMIAAAHGVLVIFGLARMR
                     ARPTRTDRTPYVYAPRTTFLIGRLLGRTRDRN"
     gene            82645..84357
                     /locus_tag="OIHEL45_00492"
     CDS             82645..84357
                     /locus_tag="OIHEL45_00492"
                     /EC_number="6.1.1.10"
                     /note="COG0143 Methionyl-tRNA synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA synthetase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00492"
                     /db_xref="CDD:30492"
                     /translation="MTRHLITSAIPYINGIKHLGNLVGSQLPADLYARYLRGRGQEVL
                     FLCATDEHGTPAELAAAKAGKPVEDYCAEMYAVQARIAEGFGLSFNHFGRSSSVQNRK
                     LTQHFAGALADQGLIEEVSQRQIYSPTDGRFLPDRYVEGTCPNCGFEDARGDQCDNCT
                     KQLDPEDLINPRSTISGATDLEMRETKHLFLRQSKLKDELDDWINSKTDWPVLTTSIA
                     KKWLHDGDGLQDRGITRDLSWGVPVKRGDQDWPGMEGKVFYVWFDAPIEYIACAQEWV
                     DAGKGSDWESWWRTDKGADDVRYTQFMGKDNVPFHTLSFPATIKGSGEPWKLVDYIKS
                     FNYLTYDGGQFSTSRGRGVFMDQALEILPADYWRWWLLSHAPETSDAEFTWENFQASV
                     NKDLADVLGNFISRITKFCRSKFGEAVPEAGEYGEAEQALIEDITARVARYETLMEAM
                     EVRKSAAELRGIWAAGNEYLQAQAPWTTFKTDPDKAAAQVRLALNLIPLYAVLSAPFI
                     PSAAASMLEAMKVADMPWPDDVPAALGKLAPNHAFEVPEVLFAKISDEDRENWSERFA
                     GKRD"
     gene            complement(84436..84807)
                     /locus_tag="OIHEL45_00497"
     CDS             complement(84436..84807)
                     /locus_tag="OIHEL45_00497"
                     /note="COG2202 FOG: PAS/PAC domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00497"
                     /translation="MVEFSKTCLVQHANEEACGVTYGLGDSLIGEYIADLFGPRLSDG
                     AEISTLLLRIVQGKQQYGCFEMLPGEETARIVEGQFTPMLGPGGEVCGIRFTGAGGAA
                     NSPRSMVEVAHGHQAKRALPH"
     gene            85228..86763
                     /locus_tag="OIHEL45_00502"
     CDS             85228..86763
                     /locus_tag="OIHEL45_00502"
                     /note="COG3300 MHYT domain (predicted integral membrane
                     sensor domain)"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase/phosphodiesterase (GGDEF &
                     EAL domains)"
                     /protein_id="jcventer:1103467007065_OIHEL45_00502"
                     /db_xref="CDD:33109"
                     /translation="MLRVAHTIHQDHDLGLVLLAALLCLFGSWVVSRLYHHVLEQPRA
                     QAMIWCYLTAMTAGVTIWCTHFIAILAYQLDAPATFHFSLTFLSLIIAIIGSTLGVVI
                     AGLGKSPRTTILGGTIFGLAISAMHYTGMVAYRVQGTINWDVEYLTASVIIAIVLTTL
                     ALGAARREVRASVLSMTALLASAIILLHFTGMAAFQVTPLTAQPVYANPVEYQLIALI
                     IAGTAAMITLAALFSYVVENRTRNESIEELRRARDAAESASRAKSEFMSVLSHELRTP
                     LTIVIGYAGFLSELKRHNLAKLSPEEKPASEHFTKMGDQAELYGQRIKFAGGQLLTII
                     NDILDYTNMELNDLALDKAAFDTRALLEEVVEEHNGAAHDKSATLHIDTLPLNVIADR
                     RRSVQVLSHIVGNALKFSKARDIYLRARPHVDGFCFEVEDNGVGIAEEDFERIFEAFT
                     QIEDADDRAEGGTGLGLAICRKLARAHGGDISVKSTLGRGTTFTVFIPGTPQVAEPAA
                     LAA"
     gene            complement(86782..86865)
                     /locus_tag="OIHEL45_t00950"
     tRNA            complement(86782..86865)
                     /locus_tag="OIHEL45_t00950"
                     /product="tRNA-Leu"
     gene            complement(86928..87404)
                     /locus_tag="OIHEL45_00507"
     CDS             complement(86928..87404)
                     /locus_tag="OIHEL45_00507"
                     /note="COG1522 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="proline dehydrogenase transcriptional activator,
                     putative"
                     /protein_id="jcventer:1103467007065_OIHEL45_00507"
                     /db_xref="CDD:31711"
                     /translation="MANELFDLDRFDSAILSVLAEDGRISITDLARRIGLSKSPTQAR
                     LRRLEESGVILGYRALLDPIRLGLDHVAFVEVRLNDTREAALRAFNLAVAKVPEIEQA
                     HMIASHFDYLIKVRTRSMSEYRRFLGEVISTLPHVASTSTYVAMEAVKETMLADTA"
     gene            87512..90928
                     /locus_tag="OIHEL45_00512"
     CDS             87512..90928
                     /locus_tag="OIHEL45_00512"
                     /EC_number="1.5.1.12"
                     /note="COG0506 Proline dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional proline
                     dehydrogenase/pyrroline-5-carboxylate dehydrogenase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00512"
                     /db_xref="CDD:33955"
                     /translation="MALDHAPALRQTIDARTYADPDAMLTELKAQADLSAEDRAQITA
                     DAAGLVRGIRDTSAPGMMEVFLAEYGLSTDEGVALMCLAEALLRVPDADTIDALIEDK
                     IAPSDWGRHMGHSTSSLVNASTWALMLTGRVLDDDQPGPVRHLRAAIKRLGEPVIRTA
                     VSRAMREMGRQFVLGEDIHAAMKRAKGMEKKGFTYSYDMLGEAARTEADAKRYHLSYS
                     RAISAIADACTHDDIRKNPGISVKLSALHPRYELAQEAAVMRDLVPRLRALALLAKSA
                     GMGLNIDAEEADRLALSLEVIDTVMGEPALAGWDGFGVVVQAYGPRAGTVIDTLYDIA
                     TRHDRRIMVRLVKGAYWDTEIKRAQVEGIDGFPVFTRKAATDVSYIANARKLLNMTDR
                     IYPQFATHNAHTVAAVLHMADDPEAYEFQRLHGMGETLHDIVMQKHGTRCRIYAPVGA
                     HRDLLAYLVRRLLENGANSSFVNQIVDENVPPEVVAADPFDQLQDSAPTIPRGPEVFQ
                     PQRANAKGFDLAHSPTLAAIEKARAPFADATWTAAPILAGDANPEAEETVSNPTGGTS
                     PGTVQPASDADVATALDNAAAWDAPLDTRRACLLRAADMFEERYGEIFAILAREAGKG
                     LPDCVAELREAVDFLRYYAGQATNTPPSGIFTCISPWNFPLAIFCGQVTAALAAGNAV
                     LAKPAEQTPLIAKLAVEVLHEAGVPRSALQLLTGGGKVGAALTGDARINGVAFTGSTA
                     TALRIRANMAEHCAPGTPLIAETGGLNAMIVDSTALPEQAVQAIVESAFQSAGQRCSA
                     VRCLYVQEDIAEDLIRMLTGAMQALNMGDPWHLSTDVGPVIDDTARKGIVEHIEAART
                     EGRVIADLKAPEGGTFVGPAILRVNSIADMKREIFGPVLHVATFKSHELDAVIDAINA
                     TGYGLTFGLHTRIDDRVQHVSERIEAGNIYVNRNQIGAIVGSQPFGGEGLSGTGPKAG
                     GPNYLPRFSAPDHQDAAGTWDSAETKLPALPAHQPIVLETQSMPGPTGESNRLSTLPR
                     PALLCMGPGAETAAAQAKAVRALGGVAVEATGQIDPEALTTGPAYGGVLWWGDDDEAR
                     KIDQALAARDGAIIPLLRGLPNTARVRAERHVCVDTTASGGNAQLLGMMA"
     gene            90956..92107
                     /locus_tag="OIHEL45_00517"
     CDS             90956..92107
                     /locus_tag="OIHEL45_00517"
                     /note="COG1473 Metal-dependent
                     amidase/aminoacylase/carboxypeptidase"
                     /codon_start=1
                     /transl_table=11
                     /product="probable hydrolase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00517"
                     /db_xref="CDD:31662"
                     /translation="MLTNSDIEDLTQFRRALHQYPEISGEEIETARTIAAELKKLSPT
                     RILMGLGGHGVAAVFDSGAPGPTVLFRAELDALPIPEEHDIPWVSKVPGKSHVCGHDG
                     HMTMLLALGRIIARQPVAKGRVVLMFQPAEEDGSGARAVVNDPAYAEIAADFAFAIHV
                     EPGRPFGHVDTAPALINCASKGVAVTLRGKTAHAASPEDGSSPAPALAELIPALQALG
                     PGGALDDGFRRVTLTHLRMGEPTFGVAPGEAVLYATLRTTRDDALAEIEEALRAEVAR
                     AAEAHRLTAEFAESDHFAASINDPEAYAIAAAAMDALGVSHGQKNLPMRASEDFGLFG
                     RDAKAAMLCLGPGEDYAALHNPDYDFPDDLIPIGAGIFERIARDLLGTA"
     gene            92190..92897
                     /locus_tag="OIHEL45_00522"
     CDS             92190..92897
                     /locus_tag="OIHEL45_00522"
                     /note="COG0705 Uncharacterized membrane protein (homolog
                     of Drosophila rhomboid)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00522"
                     /db_xref="CDD:31049"
                     /translation="MFPIRDHNPSGRTPYVTYALMAVNIGVFLSYLSLMSDERALGEF
                     YYSYALLPARLSHGEGYFGLITSQFLHGGWMHLAGNMLFLWIFGDNVEDEMGHGRYLL
                     FYLACGIAAGLGQVVTEPLSWVPMVGASGAIAGVMGGYLLLFPRAKVDILVIFIVFSA
                     SSRSLRGSCWGCGSACSSSAASGPHPAPAAWPIGRIRAGSLPGWCWPCRFGYAAAVSP
                     FGDRPTATRPMPPQGMT"
     gene            92693..92932
                     /locus_tag="OIHEL45_00527"
     CDS             92693..92932
                     /locus_tag="OIHEL45_00527"
                     /note="COG0705 Uncharacterized membrane protein (homolog
                     of Drosophila rhomboid)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00527"
                     /translation="MLGLWFGMQFIGGIGATPGTGGVAYWAHSGGFIAGLVLALPLWL
                     RRGGFAFWRQTDGHPPHAASRYDLNESRIPKVGRK"
     gene            92929..93315
                     /locus_tag="OIHEL45_00532"
     CDS             92929..93315
                     /locus_tag="OIHEL45_00532"
                     /note="COG3791 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde-activating,
                     GFA"
                     /protein_id="jcventer:1103467007065_OIHEL45_00532"
                     /db_xref="CDD:33586"
                     /translation="MTETSETRRASCHCGAVVIEALFPRGLASASRCTCSFCRRRAAA
                     TVTAVAESVTILKGAENLTLYTWGTHTAQHYFCKTCGIYTHHRRRSNPDECGVNLGAI
                     EGVLPWEMEPLPYSDGINHPSDRKGT"
     gene            complement(93312..94364)
                     /locus_tag="OIHEL45_00537"
     CDS             complement(93312..94364)
                     /locus_tag="OIHEL45_00537"
                     /note="COG3673 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00537"
                     /db_xref="CDD:33471"
                     /translation="MFGRLWRRPATDFGPRRGAVTHVIILDGTMSSLDAGSETNAGLA
                     YGLCREMGSALSIYYEPGLQWRDWRSARDVIMGRGINRQIRRAYGYLASRYRPGDRIY
                     LMGYSRGGYAVRSLAGVIDRVGLLRAEVATERNIRDVYRHYEAQSLSKAGALFAKANC
                     HPQVEIEAIGVWDTVKSLGVNAPLFWRLSQPLHMFHNHDLSGIVKNGFQALALNESRI
                     SYAPVMWTTPEGYAGRLEQVWFPGTHGDIGGQLGGHEAARPLANIPLVWLLSRMEDSG
                     LPLPEGWAARFEQDPTAPSIGQWRGYGKMLVTRRRRVVGADPSERLHESVDQRRAQVE
                     PQSGLLARMQGVISSL"
     gene            complement(94381..96678)
                     /locus_tag="OIHEL45_00542"
     CDS             complement(94381..96678)
                     /locus_tag="OIHEL45_00542"
                     /note="COG1529 Aerobic-type carbon monoxide dehydrogenase,
                     large subunit CoxL/CutL homologs"
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase, putative"
                     /protein_id="jcventer:1103467007065_OIHEL45_00542"
                     /db_xref="CDD:31718"
                     /translation="MEKFGKSQPVKRVEDHRFLTGDGRYVDDIAPRDALQGVFFRAPV
                     AHGVITELDVSDAREAEGVHLVLTCADLEAAGMNIDLPHTVVDNRDGSKGAAPLRPIL
                     AKDRVRYVGEPVALIVADTLQQARDAAELILFDADDLPAKMDLTPGGETLHTEAPDNR
                     AFDWGMGDEAKVEAAFAKAARRVKLEVGDNRIIVNSMEPRGCYAEWADGRLHVALGGQ
                     GVWAHKNFFVKAFGLSEDDVRVTNPDVGGGFGMKAMTYPEYFCIAQAARALGRPVRWM
                     SERTEAMLTDNGGRDLVSWAEFAFDENHKITAYRVDTRCNLGAYNSQFGQPIQSTLFS
                     KVLMGVYDVQDTYLHVEGYYTNTVQVDAYRGAGRPEAIYVLERLMDRAARELGIDPWE
                     LRRINFIKPDQFPYTTATGELYDVGDFARLLTRAGEEADRKGFNARRTADAKRGLLRG
                     QGLCYYIESILGDPSEGAKVVFEEDGSVAIYVGTQSNGQGHETVYAQFLSDQTGIPAE
                     QIRVVQGDSDLIKKGGGTGGSRSVTTQNTATLATVAKITEVFTAFLAEELGVNARDIS
                     FDDERFRAEGSNVSPTMLEVAEMARAKGREDLLTHDERASLPGRSYPNGAHVAEVVID
                     PETGVVTLDRYTVVDDFGNLINPMLAEGQVHGGVAQGIGQAVQERVVYDEDGQLLTAT
                     FMDYAMPRAADLPMISFTSEPVPSTANAMGMKGCGEAGTVGALAAVSNAVQDALWERG
                     VRQADMPFTPHRVWEMLQGAAIAAE"
     gene            complement(96751..97911)
                     /locus_tag="OIHEL45_00547"
     CDS             complement(96751..97911)
                     /locus_tag="OIHEL45_00547"
                     /note="COG0019 Diaminopimelate decarboxylase"
                     /codon_start=1
                     /transl_table=11
                     /product="Putative Ornithine decarboxylase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00547"
                     /db_xref="CDD:30369"
                     /translation="MQHTAPLSATPAAYLAKHSPDAPVLFLAPSVLQATARRFQADFD
                     GLVTYAVKANDRPEVLSNLVAAGITSFDVASPAEMAAVRAVCPQAVLHYNNPVRSTAE
                     VKAGIVAGVYSWSIDDMSELAKLHDVPRDNEVAVRFALPVKGAAYDFGSKFGAAPAQA
                     AALLRAVVEMGFTPSLCFHPGTQCNDPQAWVQYVHAAADILRMADVSIKRMNIGGGFA
                     VDRGFDAPDHRAVFAAVKAALAESFGAEAPTLLCEPGRAMVADAAVLATRIKGMRNEG
                     RTVFLNDGIYGGLPDLRDMGLSGLVDVVGPDGALRQGAPKPRVVFGPTCDSLDRLPDG
                     LPLPEDAQTGDYLLFGGMGAYSIAMSTAFNGYGLGRVELVSGLGDEVKRAAA"
     gene            97910..98452
                     /locus_tag="OIHEL45_00552"
     CDS             97910..98452
                     /locus_tag="OIHEL45_00552"
                     /note="COG1522 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="Transcriptional regulator, AsnC family protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00552"
                     /db_xref="CDD:31711"
                     /translation="MMASCLLSPSEPRISVDSSCQTAYTDGNFRQSDDMAHQIDDTDR
                     VLIAALQSNARLPVADLARSLGLARTTVQARLERLERSGAIVGYTLRLGEAARAPLHA
                     TALVNIELRAGPAVLARLRSLPGVQVVHTTSGRFDLLVQIAAQTTQELDETLDRIGET
                     RGVKGSESLIHLSTKIDRRG"
     gene            98545..101478
                     /gene="valS"
                     /locus_tag="OIHEL45_00557"
     CDS             98545..101478
                     /gene="valS"
                     /locus_tag="OIHEL45_00557"
                     /EC_number="6.1.1.9"
                     /note="COG0525 Valyl-tRNA synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="valyl-tRNA synthetase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00557"
                     /db_xref="CDD:30871"
                     /translation="MALEKTFNAAEAESRIYADWETKGAFKAGANAQRDEHFSVMIPP
                     PNVTGSLHMGHAFNNTLQDILVRWHRMQGFDTLWQPGQDHAGIATQMVVERELAATGQ
                     PGRRELGREAFTAKVWEQKQKSGGTIIDQLRRLGASCDWSRNAFTMSGAPGAPEGEEG
                     NFHDAVIKVFVDMYNKGLIYRGKRLVNWDPHFETAISDLEVESTEVDGHMWHFKYPLA
                     GGATYTYVEKDEDGNVLFEEERDYISIATTRPETMLGDGAVAVHPSDERYASIVGKLC
                     EIPVGPKEQRRLIPIITDEYPDKNFGSGAVKITGAHDFNDYGVAKRNGIPLYALMDTQ
                     GQMRADGLPYDEAAARAQAIADGSEAAPEDATEINLVPDAYRGLDRLKARKRVVEDVT
                     AEGLAVMTEATDPRLGRAALKAPVEPGEGGEMRTEEENLVPLIEAKKIMQPFGDRSKV
                     VIEPMLTDQWFVATDKIVQPAIDAVRSGEVTILPEQDRKVYFHWLENIEPWCISRQLW
                     WGHQIPVWFDDEGNEYCAPTEAEAQAMAPGKTLRRDPDVLDTWFSSGLWPIGTLGWPE
                     QTAELEKYFPTSVLVTGFDIIFFWVARMMMMQYAVVDQKPFDTVYVHALVRDEKGKKM
                     SKSLGNVLDPLELIDDYGADAVRFTLTSMAAMGRDLKLSTQRIAGYRNFGTKLWNAHR
                     FAEMNNVFDSMPAAMPQPQATLNKWIVGETARIREEVDAALGNFRFNDAANALYAFVW
                     GKVCDWYVELSKPLLQDDAPEAAETRATMAWVLEQCLVLLHPIMPFITEELWQTTTKR
                     EQLLALTDWPTYTTADLLDSEADRELNWVIGLIESIRSARQQMHVPAGLKVPMLVTEM
                     DAAAQGAWDRNEVMIKRLARVESLEKTDSFPKGTVSIAAPGASFGLPLAGLIDIDAEK
                     ARLQKSLDKLGKEIGGLKGRLNNPKFAASAPEEVVAEAQANLDARQEEADQLQAALDR
                     LAELG"
     gene            complement(101919..102710)
                     /locus_tag="OIHEL45_00562"
     CDS             complement(101919..102710)
                     /locus_tag="OIHEL45_00562"
                     /EC_number="4.2.1.17"
                     /note="COG1024 Enoyl-CoA hydratase/carnithine racemase"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00562"
                     /db_xref="CDD:31227"
                     /translation="MPRVTLRIEDHIAHVTLTRADKMNAVDDEMIEAIIAAGQEVAAS
                     EARVVVLSGEGKGFCAGIDIGGLSGMLGQDVEALIMPRTHGEGTTNKWQEVSMVWHRL
                     EIPVIAALHGVVYGAGMQLALGADIRIAAPDTKLAVMEMKWGIVPDMGGMVLLPRLVR
                     SDVLRRLTYTAAPIEAAQAERWGLVTEVADDPQATAMELARVIAGKGPNAVRAAKRLI
                     GYAETGASEAEVLEAESREQAALLGKPEQMEVIAAEFGKRPAVFK"
     gene            102829..103932
                     /locus_tag="OIHEL45_00567"
     CDS             102829..103932
                     /locus_tag="OIHEL45_00567"
                     /EC_number="2.6.1.9"
                     /note="COG0079 Histidinol-phosphate/aromatic
                     aminotransferase and cobyric acid decarboxylase"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00567"
                     /db_xref="CDD:30428"
                     /translation="MTHVRLTPLAQSLPANVPFVGPEAQERSLGRLFKARLGANENVF
                     GPSPRAIAAMAETEMWKYGDSESVELRAALAELHGVAPENIIVGEGIDGLLGYLVRLL
                     VGEGDAVVTSEGAYPTFNYHVAGFGGVLHKVPYRDDHEDPAALFAKAAEVDAKLVYLA
                     NPDNPMGTWHEGATLKRALDDLPQGSLLLLDEAYIECAPEGTAPELSADDPRVIRMRT
                     FSKAYGLAGARIGYAIAAPELITAFHKVRNHFGLNRAAQAGALAAVQDQSYLHEVQTK
                     IAEARDRITQIAEKNGLSTLPSAANFVAIDCGSDGTFAKAVLDALVARGIFVRMPFAA
                     PQNRCIRVSCSTPEELDIFAAALPEALTDARGA"
     gene            complement(103929..105293)
                     /locus_tag="OIHEL45_00572"
     CDS             complement(103929..105293)
                     /locus_tag="OIHEL45_00572"
                     /note="COG0075 Serine-pyruvate aminotransferase/archaeal
                     aspartate aminotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase, class V"
                     /protein_id="jcventer:1103467007065_OIHEL45_00572"
                     /db_xref="CDD:30424"
                     /translation="MLWPACCGLREVGGYLRRGLPCVRSRVDPGPAGSKLRPTAAWSR
                     IFKTAANIMTTHNKLAQGRSYLAIPGPSVMPEAVLSAMHRAAPNIYEGELVEMMPALA
                     ADLKLVARTEHHVAMYISNGHGAWEAALSNVIAPGDRVLVLATGRFGHGWAEMATGLG
                     AEVEIIDFGRNAPIDLARVAERLKADRGHQIKAVMAVHVDTSSSVRNDVPGLRRLLDE
                     EDHPALLMADCIASLGCETFEMDAWGVDVMVTASQKGLMVPPGMAFVFFNDRAEEARA
                     RLPRVSRYWDWSPRAHAEEFYQYHGGTAPTHHLYGLRTALDMIHEEGIEQVWQRHATL
                     ARAVWAAGEAWSAEGSLRFNIEDRALRSHAVTALRLQAPHATELRDWVQSNLGLTLGV
                     GLGMALPGEPAWHGFFRLGHMGHVNGHMIMGLLGGIEAGLSALKIDHGPGALQAAAEV
                     IGGA"
     gene            105371..107227
                     /locus_tag="OIHEL45_00577"
     CDS             105371..107227
                     /locus_tag="OIHEL45_00577"
                     /note="COG1132 ABC-type multidrug transport system, ATPase
                     and permease components"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux ABC transporter, transmembrane
                     ATP-binding protein , putative"
                     /protein_id="jcventer:1103467007065_OIHEL45_00577"
                     /db_xref="CDD:31327"
                     /translation="MNDESYTSAQLMRWLWRDYLKKHTGLMFIAVIFMIIEGSTLGVL
                     AKLMEPMFDRVFVGGDQGALIWVGLVLVAIFALRALATVVQKVLLTRVAQRTAADLRI
                     DLLDRMMQQDGAFHQNHPPGFLVQRVQSDVNAVSDVWRAVITGAGRDLVGLVILMGVA
                     IAIDPIWALLAMIGVPLMVLPAALAQRFVRARSREARDLGASLSTRLDEVFHGIVQIK
                     LNALEAYQARQYRELTRVFIRTEVRAAFGNSAIPAMIDIMSGIGFMAVIVYGGSEIIA
                     GNKTIGEFMTFFTALGFMFSPLRRLGSISGLWQMAAAALERIKELLDAPLHLRSPAKP
                     VAAPDGPPDIALRDVSLSYGESKVLNELSLTAKAGETTALVGASGAGKSTIFNLLTRL
                     VDPQNGTVQIGGVDTTAMAIPDLRGMFSVVTQEALLFDETLRENIVLGRDDVTDEALD
                     RVLKAAHVADFLPQLELGLETRVGPRGSALSGGQRQRVVIARALLRDTPILLLDEATS
                     ALDAQSEQVVQDALDLLAKGRTTIVIAHRLSTIRSADKIVVMDRGRATDEGTHDELME
                     RGGIYADLYRLQFRDGKTVSDARGLGALTAKQRRERLRQPNLIQRIGAMFFN"
     gene            complement(107266..107949)
                     /locus_tag="OIHEL45_00582"
     CDS             complement(107266..107949)
                     /locus_tag="OIHEL45_00582"
                     /note="COG0463 Glycosyltransferases involved in cell wall
                     biogenesis"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase, putative"
                     /protein_id="jcventer:1103467007065_OIHEL45_00582"
                     /db_xref="CDD:40622"
                     /translation="MRAPISIVIPSLNAAAALPACLAALVEGLQAGLIREVIVSDGGS
                     EDGTRALAEGWGAEVLSGAPSRGGQLRRGCEVARGDWLLVLHADTVLAPGWTDAVQDH
                     MARGGGAAGWFRLRFDQQGLAPRLVAGWANLRSGLGLPYGDQGLLLPRALYDQVGGYP
                     DQPLMEDVALARALRGRLQRLEGLAITSAEKYRRQGWLRRGGRNLWTLGRYAMGASPE
                     DLAQSYRRP"
     gene            108014..108760
                     /locus_tag="OIHEL45_00587"
     CDS             108014..108760
                     /locus_tag="OIHEL45_00587"
                     /note="COG0354 Predicted aminomethyltransferase related to
                     GcvT"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl transferase family protein,
                     putative"
                     /protein_id="jcventer:1103467007065_OIHEL45_00587"
                     /db_xref="CDD:30703"
                     /translation="MTTRRILRLTGPDTRDFLQGIVTNDIAKLDQGPVYAALLTPQGK
                     YMADFFLIAAGDGVLLDVDESLGDMLTQRLSMYKLRAKVTIEPTELHLHRGTGPAPED
                     AVADPRHPEMGWRAYRDTPQTDDTTDWNALRVAHLIPETGVELTPDTFILEAGLDRIN
                     GLDFRKGCYVGQEVTARMKHKTELRKGLTRVDVKGSAAPGTAITAEGKPAGTLYTQAD
                     GQALAHLRFDRAKGPMQADEAQVTWPGPAV"
     gene            complement(108828..109391)
                     /locus_tag="OIHEL45_00592"
     CDS             complement(108828..109391)
                     /locus_tag="OIHEL45_00592"
                     /note="COG0231 Translation elongation factor P
                     (EF-P)/translation initiation factor 5A (eIF-5A)"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="jcventer:1103467007065_OIHEL45_00592"
                     /db_xref="CDD:41197"
                     /translation="MPKINGNEIRPGNVLEHNGGLWAAVKVDHVKPGKGGAFAQVEMR
                     NLRNGSKLNERFRSADKVERVRLEQKDQQFLFEDSGMLVVMDTETYEQVQLDAELLGD
                     TRPFLQDGMMIVVEYHDAEALNARLPQKVVCKVAETEPVVKGQTAAKSFKPAVLDNGV
                     KITVPPFVDQDEDIVVNTETMEYVERA"
     gene            109614..109934
                     /locus_tag="OIHEL45_00597"
     CDS             109614..109934
                     /locus_tag="OIHEL45_00597"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00597"
                     /translation="MKDFVDGTAFNNEQGNRARKLFAAVVLAALDDAIADDKKYGNGP
                     EQIARWARSRDGREVLSCAGIDPNERVVEGLMEFVGKGVRTSVALSREESERRNAALQ
                     AEAA"
     gene            complement(110007..110585)
                     /locus_tag="OIHEL45_00602"
     CDS             complement(110007..110585)
                     /locus_tag="OIHEL45_00602"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00602"
                     /translation="MNTPAHLLLGAAVMGREGAKPLIWAALAGALLPDLSLYLLAGFA
                     LYVQGLPGSVVFGVLYYSDLWQTVFWVDNSFLVWGALLALAAWRQAGWAVALTGAALL
                     HLLFDLPLHHDDGRAHFWPLTGWIFESPVSYWDVRHGAGWVAPIEALVSTFAAITLWW
                     RRPGWILSGVTLALLLAEGLARRNWIFFFGAG"
     gene            110646..112103
                     /locus_tag="OIHEL45_00607"
     CDS             110646..112103
                     /locus_tag="OIHEL45_00607"
                     /note="COG1492 Cobyric acid synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00607"
                     /db_xref="CDD:31681"
                     /translation="MTKAIMIQGTGSNVGKSMIVAGLIRACARRGLRVRPFKPQNMSN
                     NAAVTEDGGEIGRAQALQARAAGVAPHTDMNPVLLKPQSATGAQVVVQGQIAGQQEAR
                     EFGRNKASLMPAVLQSFHRLAENCDLIVIEGAGSPAETNLRAGDIANMGFARAAGVSV
                     VLMGDIDRGGVIAQIVGTQAVLDQEDNALIRGFAVNKFRGDRSLFDAGRDDIAARTGW
                     PSLGVIPWFDAAHRLPAEDVMDLPARARSGGSGCVIAVPRPPRIANFDDLDPLAAEPG
                     VDLRMIMPGTPLPADADLVLMVGSKSTISDLEAFRAEGWDIDLAAHIRRGGHVLGLCG
                     GYQMLGKTITDPHGIEGPAAQVVGLGHLDVETTMAPLKHLSEKSGQHPASGTDLTGYE
                     IHIGETTGPDCARAWLTFDGTLEGAASPSGRVQGCYMHGIFSSDAFRRAYLGNFGVTS
                     SLDFESGVDDALDALADHVEAYMDVDLFLSLAAEV"
     gene            complement(112136..113248)
                     /locus_tag="OIHEL45_00612"
     CDS             complement(112136..113248)
                     /locus_tag="OIHEL45_00612"
                     /note="COG1062 Zn-dependent alcohol dehydrogenases, class
                     III"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde
                     dehydrogenase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00612"
                     /db_xref="CDD:31262"
                     /translation="MRTRAAVAVEAGKPLEIMEVNLEGPKRGEVLVEIKATGLCHTDE
                     FTRSGDDPEGIFPAILGHEGAGVVLEVGEGVTTLEPGDHVIPLYTPECRECEYCLSGK
                     TNLCQKIRVTQGQGLLPDGTTRFSMLDGTPIHHYMGCSTFANHTVVPEIALAKVRKDA
                     PFDKICYIGCGVTTGIGAVINTAKVEIGARCVVFGLGGIGLNVIQGLRMAGADQIVGV
                     DLNDDKEEVGRYFGMTDFVNPKSVEGDLVAHLVEVTKGGADYSFDATGNTKVMRDALE
                     CAHKGWGESIIIGVAPAGAEISTRPFQLVTGRVWRGTAFGGAKGRTDVPKIVDWYMNG
                     KIEIDPMITHKLTLDQINEGFELMHKGESIRAVVEF"
     gene            complement(113388..113849)
                     /locus_tag="OIHEL45_00617"
     CDS             complement(113388..113849)
                     /locus_tag="OIHEL45_00617"
                     /note="COG1522 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, AsnC family protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00617"
                     /db_xref="CDD:31711"
                     /translation="MSEMDATDRQLVTLLQQDSRLPNAQLAEKLNISASACWRRVKAL
                     EHTGVIKRYAAIVEPKAMGLGFEAMVHVHLTRHDASALASFISAIQSRKEVTECFATT
                     GQADYHLRVLCRDIEAYNAFLESFLFLHPAVNSATTNVILRQIKANAPITG"
     gene            113975..117376
                     /locus_tag="OIHEL45_00622"
     CDS             113975..117376
                     /locus_tag="OIHEL45_00622"
                     /EC_number="1.2.7.8"
                     /note="COG4231 Indolepyruvate ferredoxin oxidoreductase,
                     alpha and beta subunits"
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00622"
                     /db_xref="CDD:33956"
                     /translation="MTEQPREFTTYKLDDRYDLTEGRVFLTGTQALVRIMLDQARRDR
                     DAGLKTAGFVSGYRGSPLGGLDLEYWRIKSRVADAGVKFLPAVNEDLGATAVLGAQQA
                     HLDPHAEVEGVFSMWYGKGPGVDRSGDALKHGNAYGSAPKGGVLVVAGDDHGCVSSSM
                     PHQSDVAFMSWFMPTLNPASVAEYQAFGEYGIALSRFSGTWVGFKAISETVESGASVD
                     LTPDRVFNQPDYTAPAGGLHVRLGDLPSAEIETRIHHKLEAVQAFLRANPIDRHIYDT
                     PDANFGIVTTGKGHLDTMEALRLLGLDEVKCRALGIDIYKVGMVWPLALDDALDFVKG
                     KREVLVIEEKRGIIESQFKEAFYDWPGSKPARMVGKHDENLEELVPWTGELSPLKLVP
                     IIAARLHAFFPDENLVEKARALTDQPPVLLNVPGANRTPYFCSGCPHNSSTKLPEGSK
                     ANSGIGCHVMASWMDRDTAGFAQMGGEGVPWIATSMFNGGKHVFQNLGEGTWYHSGSL
                     AIRQAVAAKTNITYKILYNDAVAMTGGQPVDGPVSVAAIAQACRAEGVARIALVSDRP
                     ELLPKSDFPAETSFDHRRDLDRVQRELREIPGVTVLIYEQTCATEKRRKRKRGQMEDP
                     KKFVMINDLVCEGCGDCSLESNCLSVEPKKTEFGTKRQINQSTCNKDYSCLNGFCPSF
                     VTVEGGSRRKRSGAGLDVAGLAAQLPMPVLPKLDQPFNLLVTGVGGTGVVTVGALITM
                     AAHLEGLGSSVLDFTGFAQKFGTVLGYVRIAQRPEEVHQVRIDQAAADAVIGCDMVVS
                     SAPKASAHYRRGTRIVLNRAEMPTGDLVLNRDADLRIDDREAVIAQAVGVENLSAFDA
                     NRMAEVLMGDAVFANVMMLGFAWQKGLVPVSLTALEQAIELNGVVPDKNRAAFGFGRV
                     MAGNPEAIEAHFAPAPKPDETAEALIARRMEFLTDYQNAAYAQRYKSHLDALASKLPE
                     GSDELMRAAAKSLFKLMAYKDEYEVARLHRQSGFEERIADSFEGDYKVHYHLAPPAWP
                     TGKDGRGRPNKRKFGPWMGRAFDLLAAMKPLRGTWADPFAYGADRKLEVALIDWFEGV
                     MAKAPALPHDAALEVLSAPMEIRGYGPVKEVAAEKVQAEVAAQLA"
     gene            complement(117368..118477)
                     /locus_tag="OIHEL45_00627"
     CDS             complement(117368..118477)
                     /locus_tag="OIHEL45_00627"
                     /note="COG0662 Mannose-6-phosphate isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00627"
                     /db_xref="CDD:32101"
                     /translation="MDRLMPMPDDILAEFLLPTQELRDDLPFFTKVLGMRLESIFPAD
                     DPSVASFSGHGVRVRIERGATVAPGHLRILTDDPDSFAQGQRRLTAPNGTTVEVLPRS
                     PQVEQPETRHEFAVRRLADEAPWVIGRAGMHYRDLIPSRLGGSIIASHIRIPDGGPVP
                     DMVHYHTVGFQLIFCYRGWVDVLYEDQGDVIRLHAGDCVTQPPGIRHRVVEASPSIEV
                     IEIGVPAEHVTTIDHEMTLPNGKGNPTREWDGQTFVHHIRDQATWQPFRIPGFAARDT
                     GITKGTKGVAGIQVARFDGGTPPPSKHDADIHFTFVMEGSMLLSAEGQESRRLHAGDA
                     FVIPPGIVAQYSECSPDLELLEAGLRGDFMTTLLG"
     gene            118905..119882
                     /locus_tag="OIHEL45_00632"
     CDS             118905..119882
                     /locus_tag="OIHEL45_00632"
                     /note="COG0745 Response regulators consisting of a
                     CheY-like receiver domain and a winged-helix DNA-binding
                     domain"
                     /codon_start=1
                     /transl_table=11
                     /product="two component transcriptional regulator, winged
                     helix family protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00632"
                     /db_xref="CDD:31088"
                     /translation="MKILAVDDDPFIRELLPVVFREADYPHLTLADSGAAALELLATT
                     KEQFDCLLLDIEMPEMDGITLCRHIRALDAYQDTPILMVTSRSDATAIERAFAAGAND
                     YVTKPFDVKDIATRVHIAERMLENTQRAPRLDPHQLPTGGEPGTHEFELTDPVHIGRV
                     EQLVLPFSLGNYLSQLSRQHIDMCQVFATKIEHIDELFATCNTREFARAIAASAEAVA
                     RVVDCPQLLMTHNGSGTLLCIVTGDSLPAWPEIEILVQGELDAMDLRHDDNSPMSVML
                     SVGGPIQPNASRTQRVRKTFDRAIRRVTTRQKVKLDSSPSQKPSVSAAH"
     gene            complement(119956..120324)
                     /locus_tag="OIHEL45_00637"
     CDS             complement(119956..120324)
                     /locus_tag="OIHEL45_00637"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00637"
                     /translation="MWRVISLLPVSVCALSTVALLSTPSVATAAPHIYEGREAAALRC
                     ANTLALTAVALSAAEMIGEGEKNVMLGITVRILDRHVDGTWAQKRAAMEIMRDRRSVP
                     DTLEDYRRIAERCLVQFPIN"
     gene            complement(120326..120565)
                     /locus_tag="OIHEL45_00642"
     CDS             complement(120326..120565)
                     /locus_tag="OIHEL45_00642"
                     /note="COG1522 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulator, AsnC family
                     protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00642"
                     /db_xref="CDD:31711"
                     /translation="MTTCVFIQIRCRPGTTYRVAEEIALREIHSELYSTSGEYDLLMK
                     LYIPKGEDVGVYINDNLLDIEGIERSLTTMTFKVF"
     gene            120726..121313
                     /gene="hisF"
                     /locus_tag="OIHEL45_00647"
     CDS             120726..121313
                     /gene="hisF"
                     /locus_tag="OIHEL45_00647"
                     /EC_number="4.2.1.19"
                     /note="COG0131 Imidazoleglycerol-phosphate dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00647"
                     /db_xref="CDD:40564"
                     /translation="MRRSTLTRTTAETDITVEINLDGTGTYDNETGVGFFDHMLDQLS
                     RHSLIDIKVRAKGDLHIDDHHTVEDVGITLGQALTQALGDKRGIRRYGSCLLAMDDAQ
                     IRCALDLSARPFLIWNVDFPTSSIGTFDTELVREFFQALSTHGGITLHVDALHGFNSH
                     HIAEAAFKSVARALREAVETDPRKADAIPSTKGAL"
     gene            121318..121956
                     /locus_tag="OIHEL45_00652"
     CDS             121318..121956
                     /locus_tag="OIHEL45_00652"
                     /note="COG0118 Glutamine amidotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase, glutamine
                     amidotransferase subunit"
                     /protein_id="jcventer:1103467007065_OIHEL45_00652"
                     /db_xref="CDD:30467"
                     /translation="MLTAIIDYESGNLHSAHKAFERMARENNAGEVTVTADADVVARA
                     DRLVLPGDGAFPACMAALKGAGGLYDAMVEAVEEKGRPFLGICVGMQLMASLGREYKD
                     TPGLGWIGGEVTKITPADSKLKVPHMGWNDLVIDHDHAVFDGLKTGDHTYFVHSYHMA
                     VADPAERLAHVNYGGDVTAIIGRDTMLGMQFHPEKSQTTGLRLISNFLTWAP"
     gene            complement(122131..122706)
                     /locus_tag="OIHEL45_00657"
     CDS             complement(122131..122706)
                     /locus_tag="OIHEL45_00657"
                     /note="COG4731 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00657"
                     /db_xref="CDD:34346"
                     /translation="MHKAHSLTVFEIDGGVEDHGRALVLNIGFLLHVITDFATRPKVN
                     LARNKVMDNSKARSGGEIMKQFIAAGLLGLGLTGAAYAAGPAVGTWQTQVDDGAYAHV
                     KMAPCGGAVCGTIARTFNDSGEYKSPNIGKTLVIDMKPEGGGKYAGKVWRPSNGKIYI
                     GKMDVAGDSLKLSGCIAGGLICSKQTWARIK"
     gene            122650..123369
                     /locus_tag="OIHEL45_00662"
     CDS             122650..123369
                     /locus_tag="OIHEL45_00662"
                     /EC_number="5.3.1.16"
                     /note="COG0106 Phosphoribosylformimino-5-aminoimidazole
                     carboxamide ribonucleotide (ProFAR) isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]
                     imidazole-4-carboxamide isomerase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00662"
                     /db_xref="CDD:30455"
                     /translation="MILYPAIDLKDGQAVRLVHGDMDRATVFNDDPAAQALSFVDAGC
                     EWLHLVDLNGAFAGTPVNAAPVEAILKACKVPAQLGGGIRDMATIESWLDKGLARVIL
                     GTVAVENPDLVREAAAAFPGHVAVGIDARNGRVATKGWATETDVMATDLAKSFEDAGV
                     AAIIYTDINRDGAMGGPNVSATADLARAVSIPVIASGGVSSLDDLAALRDTGVIEGAI
                     SGRALYDGAIDLAAAMQMLKG"
     gene            123373..124134
                     /locus_tag="OIHEL45_00667"
     CDS             123373..124134
                     /locus_tag="OIHEL45_00667"
                     /EC_number="4.1.3.-"
                     /note="COG0107 Imidazoleglycerol-phosphate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="jcventer:1103467007065_OIHEL45_00667"
                     /db_xref="CDD:30456"
                     /translation="MLKTRIIPCLDVADGRVVKGVNFVGLRDAGDPVDAAIAYDAAGA
                     DELCFLDIHATHENRGTMFDLVTRTAEHCYIPLTVGGGVRTVADVRALLLAGADKVSF
                     NSAAVANPDVIAEAADHFGSQCIVCAIDAKTVSPGKWEIFTHGGRKPTGIDAVEFAQL
                     VAEKGAGEILLTSMDRDGTKQGFNLPLTRAISDAVSVPVIASGGVGNLDHLVDGVIEG
                     GASAVLAASIFHFGEYTVQEAKQHMAAAGIPMRLS"
     gene            124131..124439
                     /gene="hisE"
                     /locus_tag="OIHEL45_00672"
     CDS             124131..124439
                     /gene="hisE"
                     /locus_tag="OIHEL45_00672"
                     /EC_number="3.6.1.31"
                     /note="COG0140 Phosphoribosyl-ATP pyrophosphohydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-ATP pyrophosphatase"
                     /protein_id="jcventer:1103467007065_OIHEL45_00672"
                     /db_xref="CDD:30489"
                     /translation="MTLDDLYATILSRKEADPSSSWTAQLLAKGPEKCAEKFGEEAVE
                     AIIEAVKNDRAGLTSEAADVLYHLLVMLAARDVPLSDVLDELARRQSTSGIAEKAART
                     "
     gene            complement(124440..124853)
                     /locus_tag="OIHEL45_00677"
     CDS             complement(124440..124853)
                     /locus_tag="OIHEL45_00677"
                     /note="COG1832 Predicted CoA-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00677"
                     /db_xref="CDD:32017"
                     /translation="MTDALIKDVLTRTRRIAVVGVSPNPARPSHYVAEYLAEKGYDVV
                     PVNPVHAGKEVFGKTIVATLAEIDPPVQMVDIFRRSEDVPPVVDEALAAFPDLETIWM
                     QMGITNAEAAAKAEARGVDVIQDRCPKVEIPRLLG"
     gene            125033..126307
                     /locus_tag="OIHEL45_00682"
     CDS             125033..126307
                     /locus_tag="OIHEL45_00682"
                     /note="COG1960 Acyl-CoA dehydrogenases"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase-like protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00682"
                     /db_xref="CDD:29655"
                     /translation="MIDQTLDMNNLEMSEKAKPLLAAVTKHIRENVDPITEEFFRLGE
                     GRADRWSYAPGQLELLDGAKQKAREAGLWNFFLPNAETGEGLANLDYAYIAAELGKSP
                     LAPETLNCSAPDTGNMEVLERVGTAEQKEQWLKPLLAGEIRSAFAMTEPDVASSDARN
                     ISTSAVLDGDDWVINGEKFYISGAGDPRCKIMIVMVKTSPEAETFRQQSQILVPMDTP
                     GVEILGPMHVFGHDDAPHGHMHIRFTDVRVPRENVLWGEGRGFEISQVRLGPGRIHHC
                     MRSIGSAEKALDLMIERGLGREAFGKKIIDLGKNMETISRARIDIEAMRLMVLKAAKA
                     MDVLGNKEARIWVSMIKALVPEKACEIIDASMQVHGATGMSQWSPLSGMYTWQRALRF
                     ADGPDEVHHQVIARAEVKAFQASNTRGTKSDS"
     gene            126309..127085
                     /locus_tag="OIHEL45_00687"
     CDS             126309..127085
                     /locus_tag="OIHEL45_00687"
                     /note="COG1028 Dehydrogenases with different specificities
                     (related to short-chain alcohol dehydrogenases)"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase, short chain
                     dehydrogenase/reductase family protein"
                     /protein_id="jcventer:1103467007065_OIHEL45_00687"
                     /db_xref="CDD:40206"
                     /translation="MELQGRVIVITGAASGIGRALALRFAQEAPAHIVCVDIDGAGTE
                     ATAAKVGGTAFRVDVSSEAEIATLIAEVERDIGPIDLFCSNAGISIEGGVEVPDADWQ
                     RIWEINVMSHVRAARHLVPLMRARGGGYLLNTASAAGLLNQVGAAPYGVTKHAAVGLA
                     EWLAMTYGDDGIKVSVLCPQAVRTEMMRGLEDHVAAIDGMLEPEPVAEACVQAIRDEV
                     FLVLPHPQVRDYIQGKARDYDRWIGGMRKLNRRFGTPDAT"
     gene            complement(127095..127970)
                     /locus_tag="OIHEL45_00692"
     CDS             complement(127095..127970)
                     /locus_tag="OIHEL45_00692"
                     /note="COG1946 Acyl-CoA thioesterase"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="jcventer:1103467007065_OIHEL45_00692"
                     /db_xref="CDD:32129"
                     /translation="MTTAARQLLDLLDIEQLEVDLFRGTGAGGETSMRIFGGHVIAQA
                     LMAAYRTVPERTCHSLHAYFIRPGDPKIPVIYQVDRARDGGSFTTRRVVAIQHGKQIL
                     NLSASFQVEEEGFDWQHEMPQVSAPENWPDRPELREAFAEKLPEKYRSDFLRERPIEI
                     REVEPRDFMTPEKVGDRNYLWFRMAAAEGQGPVMQHALLAYASDMNLLGSSLRPHGLT
                     WFQGKVMTASLDHAMWFHAPIRFDEWHLYALDAPFTGGARGFNRGMIYNQNGQLVASV
                     AQEGLLRPIRPKSES"
     gene            complement(128056..129090)
                     /locus_tag="OIHEL45_00697"
     CDS             complement(1