LOCUS       DFL43       4460157 bp    DNA     linear   BCT 20-DEC-2007
DEFINITION  Hoeflea phototrophica DFL-43 1103279223844, whole genome shotgun
            sequence.
ACCESSION   DFL43
VERSION     DFL43.1
PROJECT     GenomeProject:19311
KEYWORDS    WGS.
SOURCE      Hoeflea phototrophica DFL-43
  ORGANISM  Hoeflea phototrophica DFL-43
            Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
            Phyllobacteriaceae; Hoeflea.
REFERENCE   1  (bases 1 to 4460157)
  AUTHORS   Wagner-Dobler,I., Ferriera,S., Johnson,J., Kravitz,S., Beeson,K.,
            Sutton,G., Rogers,Y.-H., Friedman,R., Frazier,M. and Venter,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2007) J Craig Venter Institute, 9704 Medical
            Center Drive, Rockville, MD 20850, USA
REFERENCE   2  (bases 1 to 4460157)
  AUTHORS   Wagner-Dobler,I., Ferriera,S., Johnson,J., Kravitz,S., Beeson,K.,
            Sutton,G., Rogers,Y.-H., Friedman,R., Frazier,M. and Venter,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2007) J Craig Venter Institute, 9704 Medical
            Center Drive, Rockville, MD 20850, USA
REFERENCE   3  (bases 1 to 4460157)
  AUTHORS   Wagner-Dobler,I., Ferriera,S., Johnson,J., Kravitz,S., Beeson,K.,
            Sutton,G., Rogers,Y.-H., Friedman,R., Frazier,M. and Venter,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2007) J Craig Venter Institute, 9704 Medical
            Center Drive, Rockville, MD 20850, USA
REFERENCE   4  (bases 1 to 4460157)
  AUTHORS   Wagner-Dobler,I., Ferriera,S., Johnson,J., Kravitz,S., Beeson,K.,
            Sutton,G., Rogers,Y.-H., Friedman,R., Frazier,M. and Venter,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2007) J Craig Venter Institute, 9704 Medical
            Center Drive, Rockville, MD 20850, USA
COMMENT     Annotation was added by the NCBI Prokaryotic Genomes Automatic
            Annotation Pipeline Group.  Information about the Pipeline can be
            found here:
            http://www.ncbi.nlm.nih.gov/genomes/static/Pipeline.html. Please be
            aware that the annotation is done automatically with little or no
            manual curation.
            
             This project was originally submitted as Oceanibulbus indolifex
            HEL-45, which is WGS project ABID00000000.
            Annotation was added by the NCBI Prokaryotic Genomes Automatic
            Annotation Pipeline Group.  Information about the Pipeline can be
            found here:
            http://www.ncbi.nlm.nih.gov/genomes/static/Pipeline.html. Please be
            aware that the annotation is done automatically with little or no
            manual curation.
            
             This project was originally submitted as Oceanibulbus indolifex
            HEL-45, which is WGS project ABID00000000.
FEATURES             Location/Qualifiers
     source          1..4460157
                     /organism="Hoeflea phototrophica DFL-43"
                     /mol_type="genomic DNA"
                     /strain="DFL-43"
                     /db_xref="taxon:411684"
     gene            complement(623..1081)
                     /locus_tag="HPDFL43_17952"
     CDS             complement(623..1081)
                     /locus_tag="HPDFL43_17952"
                     /note="COG0454 Histone acetyltransferase HPA2 and related
                     acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164408.1"
                     /db_xref="GI:163757319"
                     /translation="MGYYAREWGFGLAFETKVAAELAEFLARMDPERDLFLTAWRGGA
                     LAGSVSMDVTGGGPDGAHLRWFVVSDTARGSGLGKQLMRRAIDHADRVAAGPVWLTTF
                     AGLEAARVLYERHGFVLSAQSEDDQWQGGVREQLFTRPAPIGGQTESPQA"
     gene            complement(1149..1961)
                     /locus_tag="HPDFL43_17957"
     CDS             complement(1149..1961)
                     /locus_tag="HPDFL43_17957"
                     /note="COG0834 ABC-type amino acid transport/signal
                     transduction systems, periplasmic component/domain"
                     /codon_start=1
                     /transl_table=11
                     /product="putative solute-binding component of ABC
                     transporter"
                     /protein_id="ZP_02164409.1"
                     /db_xref="GI:163757320"
                     /translation="MFYFKSAMMAAATMFGLSAALLPAAAQASDLPDLGGETVVVVTE
                     NAYPPLQFIDPKTGDQIGWEYDAMNEIAKRLNFTVEYQNTSWDAMIQAVSDGQYQIGM
                     TGITIKEERKEKVDFSDPYMRSEMFMLVRGDEDRFTDAASFAEFEDGLVGAQAGTTPF
                     YVAVYDMLDGDEQNPRIKLMETFGATVQALKTGDVDLVLTDGTAGKGYVEASDGGLKL
                     IGEAMGTEDFGFIFPKGSELVAPINAAIADMKADGTIDALNTKWFLDYKLGG"
     gene            2529..2762
                     /locus_tag="HPDFL43_17962"
     CDS             2529..2762
                     /locus_tag="HPDFL43_17962"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164410.1"
                     /db_xref="GI:163757321"
                     /translation="MGLFGIRRFTGGWLGPILPPEDAARKSGLASRLGRSRCQRSTAA
                     QSPPPSPAARYGPPERHPSHLARNVRETIRQQE"
     gene            complement(3215..3349)
                     /locus_tag="HPDFL43_17967"
     CDS             complement(3215..3349)
                     /locus_tag="HPDFL43_17967"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164411.1"
                     /db_xref="GI:163757322"
                     /translation="MREICLVLGPRVKPEDDDGENEPRMTMERVTEDDDGESEPGMKR"
     gene            3348..3632
                     /locus_tag="HPDFL43_17972"
     CDS             3348..3632
                     /locus_tag="HPDFL43_17972"
                     /note="COG2827 Predicted endonuclease containing a URI
                     domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164412.1"
                     /db_xref="GI:163757323"
                     /translation="MTGYVYIVTNHKHGTLYIGVTSDLARRIHEHREAGTPGFASKYG
                     CRQLVWYEEHFNIAGAIQREKSLKRWYRKWKIELIESVNPDWRDLYDELW"
     gene            complement(3809..4066)
                     /gene="rplS"
                     /locus_tag="HPDFL43_17977"
     CDS             complement(3809..4066)
                     /gene="rplS"
                     /locus_tag="HPDFL43_17977"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="ZP_02164413.1"
                     /db_xref="GI:163757324"
                     /translation="MSLPVLVNTGKHAVVPQIALPVRPDNGTASQRTNAKKTSAERSL
                     EAELKAMGDKAPASKAKSSPFEAGADMWDLLASAARNEAGR"
     gene            complement(4313..4879)
                     /locus_tag="HPDFL43_17982"
     CDS             complement(4313..4879)
                     /locus_tag="HPDFL43_17982"
                     /note="COG0335 Ribosomal protein L19"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="ZP_02164414.1"
                     /db_xref="GI:163757325"
                     /translation="MNIIAQLEAEQAAKIEASRKFPEFSAGDTLRVQVRVTEGKRTRL
                     QAFEGVCIARAGAGLNESFTVRKISYGEGVERVFPMYSPLVEAVEVVRRGKVRRAKLY
                     YMRDRRGKSARIVENTNTRARKLNDAERQALAEEKARIEAEKIAAAEALAAEKAAADA
                     AEAAAAKAAADEAAAAEAAAPAEEAKSE"
     gene            complement(5082..5786)
                     /locus_tag="HPDFL43_17987"
     CDS             complement(5082..5786)
                     /locus_tag="HPDFL43_17987"
                     /note="COG0336 tRNA-(guanine-N1)-methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N(1)-)-methyltransferase"
                     /protein_id="ZP_02164415.1"
                     /db_xref="GI:163757326"
                     /translation="MGFRATVLTLYPEMFPGHLGVSLAGRALERGDASLEPVNIRDYA
                     TGKHRNVDDTPAGGGAGMVLRSDVLARAIDAVSPEGDTRPRLLMSPRGRPLTQARVRA
                     LADGPGAMIVCGRFEGVDQRVIEARNLEEVSIGDYVLSGGEPAALILLDAVIRVLPGV
                     MGNAESGSHESFETGLLEHPHYTRPQLFEDREIPAVLTSGNHKAVEEWREAESLKLTR
                     ARRPDLLAQRKITDIG"
     gene            complement(5786..6394)
                     /gene="rimM"
                     /locus_tag="HPDFL43_17992"
     CDS             complement(5786..6394)
                     /gene="rimM"
                     /locus_tag="HPDFL43_17992"
                     /note="COG0806 RimM protein, required for 16S rRNA
                     processing"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA-processing protein"
                     /protein_id="ZP_02164416.1"
                     /db_xref="GI:163757327"
                     /translation="MPTLEMSMSKLENPILIGIIGAAQGIRGEVRVKPFTEDPMAIAE
                     YGALYSEDGRRFEILDHRLAKTVVVVRFRGINDRNAAEALKGLNLYIDRSSLDDEDLE
                     EGEYFHADLEGLEAWDAEGQFWGEVSGVLDFGGGDLLELREDGRKPVVIPFTLAAVPK
                     VDLEAGRILVDPIAAGLIDTGEDDEPGEGFDGKGEGPGGARD"
     gene            complement(6474..6887)
                     /locus_tag="HPDFL43_17997"
     CDS             complement(6474..6887)
                     /locus_tag="HPDFL43_17997"
                     /note="COG0228 Ribosomal protein S16"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="ZP_02164417.1"
                     /db_xref="GI:163757328"
                     /translation="MALKIRLARGGSKKRPYYHVVVADVRSPRDGRFIERLGYWNPML
                     AKDDAARVSLNQERIQHWLDNGALPTDRVARFMAEAGMMTREARNNPNKAQPGKKAQE
                     RAAEKKQKEEDAAAAAAEAAAAPAEEAPVEEAAAE"
     gene            complement(6969..7265)
                     /locus_tag="HPDFL43_18002"
     CDS             complement(6969..7265)
                     /locus_tag="HPDFL43_18002"
                     /EC_number="5.4.99.5"
                     /note="COG1605 Chorismate mutase"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="ZP_02164418.1"
                     /db_xref="GI:163757329"
                     /translation="MSTNTEAMAKLLEYRRSIDNFDAALIHILAERFRVTKAVGALKA
                     SAELPPSDPNREAEQVARLRDLAKSSDLDPDFAEKFLEFVIREVIQHHKQAASK"
     gene            complement(7276..8904)
                     /locus_tag="HPDFL43_18007"
     CDS             complement(7276..8904)
                     /locus_tag="HPDFL43_18007"
                     /note="COG0541 Signal recognition particle GTPase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164419.1"
                     /db_xref="GI:163757330"
                     /translation="MGWRPLQQKQDDVMFENLQDRLGSILNNLTGRGALSDKDVSEAM
                     REVRRALLEADVALEVVRGFTDRVREKAVGAEIVKSIKPGQMVVKLVHDELVALLGEE
                     GVAIDLNAAAPVVIMMVGLQGSGKTTTSAKIAARLEKRDRKKVLMASLDTRRPAAQEQ
                     LRQLGEQTGVATLPIIAGQSPTDIAARAVQAAKLGGHDVVILDTAGRTHIDEPLMAEM
                     AEIKRRANPHEILLVADALTGQDAVNLARNFDERVGISGLVLTRMDGDGRGGAALSMR
                     AVTGKPIKLIGTGEKMDALEEFHPRRVADRILGMGDIVSLVEKAAENFDAEKAQTMAA
                     RMKSGKFDLNDLADQLGQMQKLGGMGGIMGMMPGMGKMKDQMSAAGMDDKTFARQLAI
                     IGSMTKAERANPDILKHSRKKRIAAGSGTDAAAINKLLKMHRQMGDMMKAMGGKGKGG
                     GMMRAAMGGLAQKMGLPGGMGGMGGMPDLSKMDPKQLEALQKQAEAAGLGKGGLPGGL
                     PGGMPGGLPGGLPGLGGPKLPGLGGGLPGLPKKK"
     gene            complement(9193..9459)
                     /locus_tag="HPDFL43_18012"
     CDS             complement(9193..9459)
                     /locus_tag="HPDFL43_18012"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164420.1"
                     /db_xref="GI:163757331"
                     /translation="MTMSAVIVRVPDENADRLEQLAAKQDRSRAYMAAKAIEDFVARE
                     ERQLAEIEAGVGEGVNQAAIAVLAGSRPRANWCWRMRPKSSPIA"
     gene            complement(10051..10551)
                     /locus_tag="HPDFL43_18017"
     CDS             complement(10051..10551)
                     /locus_tag="HPDFL43_18017"
                     /note="COG3668 Plasmid stabilization system protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164421.1"
                     /db_xref="GI:163757332"
                     /translation="MVSRSERAKKLIQETADCLLPWLPHRWPFHANAAQVAAIHHPSP
                     QSAARSFKPPFGKFESEIKPDGNPECPQALVLAPKAQDDLTEIFIYLAHEDVGIATRF
                     VADLNAKIEWIAKTGFTGVPRDWIRPGLRALPYRERCIYFRIDGDAVIVLRVIHGRQD
                     VAAQEF"
     gene            complement(10545..10709)
                     /locus_tag="HPDFL43_18022"
     CDS             complement(10545..10709)
                     /locus_tag="HPDFL43_18022"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164422.1"
                     /db_xref="GI:163757333"
                     /translation="MNLNNGAVDERIFEVGVTAHGFEKTLEYSRLRPAAKPPKLTVPI
                     PESWRQVAPW"
     gene            10650..10775
                     /locus_tag="HPDFL43_18027"
     CDS             10650..10775
                     /locus_tag="HPDFL43_18027"
                     /codon_start=1
                     /transl_table=11
                     /product="Transposase and inactivated derivative"
                     /protein_id="ZP_02164423.1"
                     /db_xref="GI:163757334"
                     /translation="MSGDPDLEYALIDGTIVQVHQKAAGAKGGLRLRPSGAHAAA"
     gene            10814..11158
                     /locus_tag="HPDFL43_18032"
     CDS             10814..11158
                     /locus_tag="HPDFL43_18032"
                     /note="COG3293 Transposase and inactivated derivatives"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transposase"
                     /protein_id="ZP_02164424.1"
                     /db_xref="GI:163757335"
                     /translation="MVRFLLLPGHAHDMKGVAPLIRDVSFGALMADKAFDANWLLEEL
                     DERGASAVIPPKSNRKQQRDYDVEAYKWRHLVENYFAKIKEFRGIATRYDKTDCSYTA
                     SWNLAATLIASR"
     gene            complement(11172..11450)
                     /locus_tag="HPDFL43_18037"
     CDS             complement(11172..11450)
                     /locus_tag="HPDFL43_18037"
                     /note="COG3609 Predicted transcriptional regulators
                     containing the CopG/Arc/MetJ DNA-binding domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164425.1"
                     /db_xref="GI:163757336"
                     /translation="MANVKKSYVVGDRYEAFIAEKVASGRFNNASEVVRAGLRMLEDY
                     ETRLVETRALVDIADAEIAAGEGIEYAGGQDITDEIVKRGMVRLSQKD"
     gene            11756..12391
                     /locus_tag="HPDFL43_18042"
     CDS             11756..12391
                     /locus_tag="HPDFL43_18042"
                     /note="COG1272 Predicted membrane protein, hemolysin III
                     homolog"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164426.1"
                     /db_xref="GI:163757337"
                     /translation="MYPTYTRSERIADGSMHAIGVTGALLGAILLLVWAAPVASPLEI
                     TAISVYAITLIGTFSASAFYHMTPWESLRPVLRRIDHAAIYLKIAGTYTPLVVMIGSG
                     LAYVVLAVVWALALVGMVLKLVFWSKPGQFGPALYLIMGWMSVVLFWSAWSQLPIGYI
                     IAGGLLYTVGVVFYAAKKMKFSNAIWHGFVIAASACFFAAITVVTTQPAIA"
     gene            complement(12411..12986)
                     /locus_tag="HPDFL43_18047"
     CDS             complement(12411..12986)
                     /locus_tag="HPDFL43_18047"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164427.1"
                     /db_xref="GI:163757338"
                     /translation="MMWRRKFLRKLALIGAVGPSFLSTVTYAGVKLEGIDGMAGQALI
                     AALREIGKPVCSQMAAKLEADGFPASGFDLHLRRAGLSPQDALAIAQGLNALRLHDAR
                     AMRSFSISYNQEIGETGAVALVDALPASLPEIGMVGCDLGDESGEALMQFALDAPKLK
                     MMCIENNAFSPEMRRRLETLRTLRSDMFLVV"
     gene            complement(13176..14942)
                     /locus_tag="HPDFL43_18052"
     CDS             complement(13176..14942)
                     /locus_tag="HPDFL43_18052"
                     /note="COG0471 Di- and tricarboxylate transporters"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA-C"
                     /protein_id="ZP_02164428.1"
                     /db_xref="GI:163757339"
                     /translation="MTTEQIMLFGILIVLFGMLVWGRFRYDLVAFVALLATVLLGLIE
                     PGAAFGGFGHPAVVIIALVLIVSRGLMNSGAVELIARFVISSDRPLPVHIGVMAVAGA
                     ALSAVINNVAALALLMTLDIDAARKAKRAVSLSLMPLSFGTILGGMITLIGTPPNIVI
                     AQYREDALGAPFSMFDFAPVGIAVAVVGIAYVAFIGWRLLPARPDAVSLEGDAGLYVA
                     EARVKEGSRSIGQTVGDLYSLANDSDVTILGLVRQGKRLPGFSRARELRQGDFLALEG
                     DPKQIEAFMGAAELDTVGAEHHGGLLGKSLSLVEVIVPEDARIVGRTTAGLRLVQKHG
                     VTLLGVSRQGKRFRERVRNLPVKAGDVLLLIGPDDNIAAASAWLGVLPLENRRLEVLQ
                     RTKALAALAIFAASIALTVIGVAPLTISLGLCVVAYLALGVIGGRDFYALIEWKVIVL
                     LACLIPVGAALEQTGGSQLIAGLIVTQTVDLPPWAVLMVLMVITMTLSDFLNNVATAL
                     IAAPIGVSIANTLDVSPDPFLMGVAVAASCAFLTPIGHKNNTIIMGPGNYQFGDYWRM
                     GLILEVIVIAVSVPMIVWVWGF"
     gene            15129..15590
                     /locus_tag="HPDFL43_18057"
     CDS             15129..15590
                     /locus_tag="HPDFL43_18057"
                     /note="COG1846 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="Transcriptional regulator, marR family protein"
                     /protein_id="ZP_02164429.1"
                     /db_xref="GI:163757340"
                     /translation="MFNHEDIVLHWVNRIGFLSRSELAARFRAAGHSISAEEWALLLM
                     LWAKGPRTPGELAQETVKDRTTVTRLIDAMVRKDLVTRSEDLADRRRSIITLSRHGED
                     LKHLLIPIAQAFIAEAVAEIPVDDMETTLRTLRKITETLTARTGPDAPERS"
     gene            15593..16309
                     /locus_tag="HPDFL43_18062"
     CDS             15593..16309
                     /locus_tag="HPDFL43_18062"
                     /note="COG0526 Thiol-disulfide isomerase and thioredoxins"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase/ Thiol specific
                     antioxidant/ Mal allergen"
                     /protein_id="ZP_02164430.1"
                     /db_xref="GI:163757341"
                     /translation="MQDYNYDGFSTNDYEFDTQTGAALGHKALDFTLETVDGESRNLL
                     DFPGDFLVLELGSITCPLFQSRRTIMEPLQREFPNATSAVLYVREAHPGANIPAHKSF
                     VDKAHCARRLKQFDGETRTIFIDDLEGHAHKAYGSMPNAVFIINKHRCVVFHAEWNNP
                     TATRKALRQLTDNSPVTARSFFFPATPAVALRTLGHAGKGAAPDFFRGLPFLIWVNII
                     KRNLRLLFNRPAQYSAETRC"
     gene            complement(16330..17313)
                     /locus_tag="HPDFL43_18067"
     CDS             complement(16330..17313)
                     /locus_tag="HPDFL43_18067"
                     /note="COG0715 ABC-type nitrate/sulfonate/bicarbonate
                     transport systems, periplasmic components"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164431.1"
                     /db_xref="GI:163757342"
                     /translation="MKHILAALALLVALPVQAAEKLTVALDWTPNTNHVGLYVAQAKG
                     WFTDAGLDVEILPYTDTSSGTLVATGVAEFGILSAVGFHSQRSMGADMTAVMAVVQHE
                     TGRLVFNGEREDIQRPADLDGKIYAGFGSAWENALISSIIRHDGGEGRFETVTLGTSA
                     YEALANGSVDFTLEVRTWEGVNSVLLGRPQRAFNYADYGVPDQHTTFLGGNATWLAAN
                     PATAEAFVKAAQRGYEFAADNPDEAGDILIAETNGMLSNPDLVHASMQALVDGGFLRD
                     PGEPAGLIDPELISGITAFLFEAGILRDANGDVHKAMPDVSGWTTNQYLAQ"
     gene            complement(17316..18065)
                     /locus_tag="HPDFL43_18072"
     CDS             complement(17316..18065)
                     /locus_tag="HPDFL43_18072"
                     /note="COG1116 ABC-type nitrate/sulfonate/bicarbonate
                     transport system, ATPase component"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein of ABC transporter"
                     /protein_id="ZP_02164432.1"
                     /db_xref="GI:163757343"
                     /translation="MSALMLANLAVTLGGTPVLDNISLSVARGEFVSILGPSGAGKST
                     LFRLLTGAIRPDAGTILVDGAPLSQTQRIFAFMPQRDALMPWRRIIDNVTLGLEVQGV
                     DREAARRHVLPMFPAFGLEGFERHYPAQLSGGMRQRAALLRTIVQDRPIQLLDEPFGA
                     LDALTRAEMQRFIERSWSQARWTIVLVTHDVREAVALSDRIYVFSRRPARILTEFHVP
                     WPRPRLGGSLPPEASRLEAELLDTLLNQTGD"
     gene            complement(18062..18850)
                     /locus_tag="HPDFL43_18077"
     CDS             complement(18062..18850)
                     /locus_tag="HPDFL43_18077"
                     /note="COG0600 ABC-type nitrate/sulfonate/bicarbonate
                     transport system, permease component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane component of ABC
                     transporter"
                     /protein_id="ZP_02164433.1"
                     /db_xref="GI:163757344"
                     /translation="MARLLSRLPAARFRRVLPAILSVAALLAAWEVYVRASGILALVL
                     PAPSRVIGQIVANREILWANTLPTLTATLTGFACSLSVAFALSVLIDFIPRLRRALFP
                     VFVISQTLPLVAIAPLVVLWFGFGLTPKILLVALVTFFPMLIALVDGYHSTDRDISAL
                     LASMGASRATIFRRARLPSATPYFFAGLRISITYAVVAAIFAEYVGARAGLGIVILNA
                     KNSFRPDLMLAAVVISSALTLALFAATALAQRMVLGWRHAGAGQ"
     gene            complement(18855..19463)
                     /locus_tag="HPDFL43_18082"
     CDS             complement(18855..19463)
                     /locus_tag="HPDFL43_18082"
                     /note="COG1048 Aconitase A"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164434.1"
                     /db_xref="GI:163757345"
                     /translation="MFAGAQVSLYPMTDGFVDVIMSSLSALDPYRERLRIETDDISTL
                     IVGPPEVLFPALRDLYVAAAASRQHVVLRATLSRGCPGEPDDPICQTNALANPSEPLD
                     SRQAGALAALAETPQTGETARAQFSLYVMGAGDHMAEIMGCIDFLKRSGTFDRSKNFC
                     TRLIGDSGPVFATLQEAFCRFGPPQGHVTIDLTVSANSPSIA"
     gene            complement(19743..21389)
                     /locus_tag="HPDFL43_18087"
     CDS             complement(19743..21389)
                     /locus_tag="HPDFL43_18087"
                     /note="COG2199 FOG: GGDEF domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164435.1"
                     /db_xref="GI:163757346"
                     /translation="MSFSTPLLVVITVLVILLIVITVRSPQAPGRTAFGLAAVASLWW
                     TAMVVLRLNSDDLTDKIMFSRLAWFGIMATPLFWSAALLDHAGFSQVTKRLPITIMFI
                     VSALAGLGALTDGYHHGLYTGIINEERPSFTYGWLFYTLLLVAYLCMMLACAMSISQL
                     KRAARLHRNQMIALLIATCVPWACNAAFVLFGFRLFNDDPTPFAFGATVLSVLFAQHR
                     GKLFTAPPIARGIIFSVLPDPIVVLAPSGLVLEMNPAAEKLTGFSNETVGTTLPPFHP
                     LMGLVAADGGPGTKKPIVHFAAMGKIFEVSVQPLERWGRQGSIMFVLRDVTEREAAQQ
                     SLSDTGKALKLRLEENLRLQEKLERQAFEDHLTGLFNRRHASSTMPPVLASAREDAPV
                     SLIIVDLDYFKQVNDRHGHDVGDKVLQAFARILSDSLQAGEIAFRYGGEEFLIVLPGA
                     GRNQALERCSLWRQELAALTIVELKDDQLSFSAGIAFAPEAGASLTECTKAADIALYR
                     AKISGRNTDVVWGEHLGGMSRDGSTDNRNAVERRTHRAWV"
     gene            21601..22656
                     /locus_tag="HPDFL43_18092"
     CDS             21601..22656
                     /locus_tag="HPDFL43_18092"
                     /note="COG2220 Predicted Zn-dependent hydrolases of the
                     beta-lactamase fold"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164436.1"
                     /db_xref="GI:163757347"
                     /translation="MSALAGLFGLGASGTAMALIRANNPYHSGPVSDHFDGTRFFNPD
                     GSAPKGFSELLKWKLGETSETWPASASSPFAPAKPEARVEGDALRITMVGHATMLIQT
                     AGINILTDPVWSDRASPVSFAGPKRIIDPGVAFEDLPKIDLVLLSHNHYDHLDLTTLA
                     RLRQAHNPLVITPLGNDAIIKNHTPGMQIMTGDWGQAVKSGPATIHFEPCHHWSARGM
                     NDRSMALWAAFVIETSGGKILHIGDTGFDKGRPYTNARERHGKFRAAILPVGAYEPRW
                     FMKDQHQNPEEAIEGFVLSGADYALGHHWGTFQLTNEGRDAPKDVLNAALAQKGVAPE
                     RFRPLHVGEVWDLPQTA"
     gene            22738..23616
                     /gene="dapF"
                     /locus_tag="HPDFL43_18097"
     CDS             22738..23616
                     /gene="dapF"
                     /locus_tag="HPDFL43_18097"
                     /EC_number="5.1.1.7"
                     /note="COG0253 Diaminopimelate epimerase"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="ZP_02164437.1"
                     /db_xref="GI:163757348"
                     /translation="MESTVPFAKMNGLGNDIVVIDMRGRSDAVTSEAAIALASGDRTG
                     FDQIMAIHDIDLDGVDYRIDILNRDGSRSQACGNGTRCVVQALASETGRKSFTFKTLA
                     GILTAEEHEDGLISVDMGRPEFAWDKIPLAEEFHDTTRIELQIGPIDAPVLHSPSAVA
                     IGNPHAVFWVKDDVWSYDLERFGPLLENHPIFPERANISIARVIDDHTLDIRTWERGT
                     GLTRACGSAACAAGVSAARTGRTGRTVTVNVPGGPLEIEWRENNHVIMTGPAEWEFSG
                     RVDPLTGAWQADEVLA"
     gene            23622..24989
                     /locus_tag="HPDFL43_18102"
     CDS             23622..24989
                     /locus_tag="HPDFL43_18102"
                     /note="COG0621 2-methylthioadenine synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164438.1"
                     /db_xref="GI:163757349"
                     /translation="MKVVTFGCRLNTFESETMRKAAETAGLNNAVLVNTCAVTADAVR
                     QARQTIRRLRRDNPHARIVVSGCAAQTEPETFAGMDEVDAVIGNDAKGEAATYRKLPD
                     FGVSQSEKIRVNDIMAVRETAPQMIEAVAGHARAFVQVQNGCDHRCTFCVIPYGRGNS
                     RSVPMGAVVDQIRTLVENGYQEVVITGVDATSYGADLPGRPSLGTLARTILNQIPELQ
                     RLRLSSIDSIEVDDALMDLIADEPRFMPYLHLSLQHGDDMILKRMKRRHSRDDAVSFC
                     RTVRDLRPGFAFGADLIAGFPTETEEMFARSLEIIEACGISFLHVFPYSPREGTPAAR
                     MPQLDRGLIKTRAARLRDSGEKAYRAHLGEMARTGGIHSALVEFSGIARTENFTPVVA
                     PGAPKGQMALIRVTGQDGERLTGELAEGPVGGELGGKAGGQRVALSHDAAWQPGLSAL
                     PASSI"
     gene            25008..26597
                     /locus_tag="HPDFL43_18107"
     CDS             25008..26597
                     /locus_tag="HPDFL43_18107"
                     /note="COG0552 Signal recognition particle GTPase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative cell division protein"
                     /protein_id="ZP_02164439.1"
                     /db_xref="GI:163757350"
                     /translation="MAFNFIKKVFSFGKTKDEAPAPESEPQMETPAAPPETAPPESSP
                     AQTPQADTAQTEAAPGPEPVAPDVTPDPDVEEPAAAATAETEQSFPHNPGEMHFTPET
                     AGNGTLSAPEPQDEEHSGEPPLSGEEPDQGAVAETPDQVTLADIAADPAIEQIAATEA
                     FETADPEPAADTEPEPEPEPEPEPEPEPEPEPEPEPEPRKLIVRDEVSSVQTATEPAP
                     TEPEPQGGWWQRLRQGLSRTSGQLTGQITGIFTKRKLDEETLEELEDVLLQADLGVET
                     ALRITDALASGRYGKDISPAEVQKVMADEIARVLEPVAKPLELDLSHKPHVILVVGVN
                     GTGKTTTIGKLAAKLHSGGLKVTLAAGDTFRAAAIEQLKIWGDRTGSKVVSTKLGADA
                     AGLAYEAFETARADGADVLIIDTAGRLQNRTELMDELAKVVRVIGKLDPDAPHTVLQT
                     LDATTGQNALNQVEIFKNVAGVNGLVMTKLDGTARGGILVAIAAKHKLPVYFIGVGEG
                     VDDLEPFEAADFASAIAGEPT"
     gene            26594..27292
                     /locus_tag="HPDFL43_18112"
     CDS             26594..27292
                     /locus_tag="HPDFL43_18112"
                     /note="COG2917 Intracellular septation protein A"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular septation protein A"
                     /protein_id="ZP_02164440.1"
                     /db_xref="GI:163757351"
                     /translation="MNDKSPDKQVAGEDPAPLFERDPNDPKRKHINPALKMALELGPL
                     LVFFFANARGDWIAERVPFLADIGGPIFVGTACFMIATAISLSVSWSLTRTLPMMPLV
                     SGIIVLVFGALTLWLQDETFIKVKPTIINTLFGGILLGGLLFKKSLLGYVFDSAFRLD
                     AEGWRILTLRWGIFFLVMAVVNEVIWRNFSTDFWIAFKVWGNLPLSIVFTLLQLPLMQ
                     RHALPEEDEEETKS"
     gene            27427..28614
                     /locus_tag="HPDFL43_18117"
     CDS             27427..28614
                     /locus_tag="HPDFL43_18117"
                     /note="COG2124 Cytochrome P450"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450 family protein"
                     /protein_id="ZP_02164441.1"
                     /db_xref="GI:163757352"
                     /translation="MLDLQNLPGGFHDNPFPHYDRLLLHAPVCLQPDGSVLLSRHADL
                     ERIYKDTGLFTSDKRAAFKPKFGENSPLFEHHTTSLVFNDPPLHTRVRRIMSSALTPR
                     AISRLEPGLIGTVDALLDALPQKADLIEDFAAQIPIQIIGNLLDVPMADRAPLRDWSL
                     AILGALEPVLTPAQQAQGNQAVAEFKAYLQDLIAHRRQHPGDPETDVLTRLTAGDEGG
                     KLSEIELIQNCIFILNAGHETTTNLIGNALAMLNDHAEEQARLRANPELINSCVEEVL
                     RMASPNQFGNREAARDTEIDGVAIPAGTNLHLCIGAANRDPAVFGNPGSFNIARKPNR
                     HLAFAGGPHICVGLTLARLEGRVALTRFLNRFQSYRITSRQQGGRIRFRGFARLEAEL
                     SGG"
     gene            complement(28695..29915)
                     /locus_tag="HPDFL43_18122"
     CDS             complement(28695..29915)
                     /locus_tag="HPDFL43_18122"
                     /EC_number="2.7.1.11"
                     /note="COG0205 6-phosphofructokinase"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="ZP_02164442.1"
                     /db_xref="GI:163757353"
                     /translation="MFHGKVLVAQGGGPTAVINQSMVGAVLESRKFRAVELIYGAVHG
                     VSGILDEDFYDLTQETTHNLEMVANTPSSALGSTRDKPDLKYCQELFKVLRAHQIGYF
                     FYTGGNDSSDTVRIVNDEARKAGYDLRCIHIPKTIDNDLVENDHTPGFPSAARYVAQA
                     FMGINLDNAALPGVYIGVVMGRHAGFLTAASALGKKFSDDGPHLIYMPERTFEIDGFL
                     SDVKQVYERYGRCIVAVSEGIHDASGEPIITKLSRAIERDAHGNVQLSGSGALADLLT
                     QKVKDELGITRVRGDTLGYIQRSFVGCVSDVDQNEAREVGEKAVQYGMFGDRDGSVTI
                     KRTGHYSVDYELVPLELVAGKTRTMPDEFIAASGHDVTDAFRMYLRPLLGSGMPDAHR
                     LRPNKVPKILAVRS"
     gene            30028..30150
                     /locus_tag="HPDFL43_18127"
     CDS             30028..30150
                     /locus_tag="HPDFL43_18127"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164443.1"
                     /db_xref="GI:163757354"
                     /translation="MALAADSVMRLVAGMGNCGPNADVLLKGIEQQLSALRLSF"
     gene            complement(30182..31183)
                     /locus_tag="HPDFL43_18132"
     CDS             complement(30182..31183)
                     /locus_tag="HPDFL43_18132"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164444.1"
                     /db_xref="GI:163757355"
                     /translation="MYDLIQLIENSSRTINSDFCRWFKNVPPAAGWNVVSDYSLGDSN
                     KQNDAFSFVIFPNHDTLDNIASYIAAVAPRDIKASRKPSQGLLDYLCCPVTFSFSFLV
                     ERQSRYLRSVITLTEMKGLADVLQAIVREWAVEEPPNAAYYEAVGQRLRLLAAELAKK
                     DPSLKLLRQIFIVASFATIVLAMVNDAKSPLTIRWISDRDAMFDRHDGIAFDLAWVLF
                     QCMRRIKGGVVDLRRPQLAFATPGMDGVTEYAEFVRLADYLAGTLADIKLPQMMFTHP
                     KFPPVFNRLLVNSPNNAVIELVDAEIGIKSRRLVFGEPPIGATSARRRGEGDSSRGS"
     gene            31423..32409
                     /locus_tag="HPDFL43_18137"
     CDS             31423..32409
                     /locus_tag="HPDFL43_18137"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164445.1"
                     /db_xref="GI:163757356"
                     /translation="MKFKDRNLRVLAEAVIGDAPNFPYRSSSYITRFFEECDMDYAHD
                     GSTRWAWTSGVLAELLAEPSSGPYALPERFVHVFRVLMHKADAEEDDPNRALALEHIN
                     KPFSREGFEAYYGEDELLYIRHIGTNTISQAANPHRPFTPKELERRENLSGYLDKCSE
                     DELIEEVLLPLFRQLGFHRIQAAGHTDKALEYGKDIWMRYVLPTQHVLYFGIQAKKGK
                     IDAAGMSKGSNRNISEIYQQVLMMLGHEIFDPETSKKALVDHAFIVAGGEITKQAKNW
                     LGQKLDATKRSQIMFMDRDDILNLFTVTNQPLPSGALPEATHSFGLDDDIPF"
     gene            complement(32597..33124)
                     /locus_tag="HPDFL43_18142"
     CDS             complement(32597..33124)
                     /locus_tag="HPDFL43_18142"
                     /note="COG1051 ADP-ribose pyrophosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164446.1"
                     /db_xref="GI:163757357"
                     /translation="MNTQKSFQRIIPDGDTHERDVCATCGFVNYQNPRIVVGSVVRHE
                     GKVLLCRRAIEPRRGFWTVPAGYLELNETPEDGARREAREEALAHLKLGELLAVYSVP
                     HLSQVQLIWRAELMDPGAGAALFGIGEESLEVELFDWDNLPTGEIAFPTVHWMLGHER
                     EVMAKGYQGPFGNPG"
     gene            complement(33230..33853)
                     /locus_tag="HPDFL43_18147"
     CDS             complement(33230..33853)
                     /locus_tag="HPDFL43_18147"
                     /note="COG0526 Thiol-disulfide isomerase and thioredoxins"
                     /codon_start=1
                     /transl_table=11
                     /product="putative thiol:disulfide interchange protein
                     (cytochrome c biogenesis protein)"
                     /protein_id="ZP_02164447.1"
                     /db_xref="GI:163757358"
                     /translation="MADGASKDTATTPSGGSGAGKRWILAFLPLVLFMGLAGVFLYQL
                     GSGKNASEIPSVLIGSKAPSLNLPPLEGLVENGQAVPALTDAAIEGRLSLVNVWASWC
                     VPCRQEHPILLELANDPRVELVGINYKDKTPNALTFLGELGNPFTAVGVDPAGQAAID
                     WGVYGIPETYLVGPDGTILFKQIGPFTPESLRDKLLPAIEKAMSPGS"
     gene            complement(33853..34020)
                     /locus_tag="HPDFL43_18152"
     CDS             complement(33853..34020)
                     /locus_tag="HPDFL43_18152"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164448.1"
                     /db_xref="GI:163757359"
                     /translation="MSHEAFVFWSYAATAVTLGGLLIAILLDGRARRRELSELEAQGV
                     RRRSDAKRDAS"
     gene            complement(34034..34795)
                     /locus_tag="HPDFL43_18157"
     CDS             complement(34034..34795)
                     /locus_tag="HPDFL43_18157"
                     /note="COG0755 ABC-type transport system involved in
                     cytochrome c biogenesis, permease component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative heme exporter c (cytochrome c-type
                     biogenesis protein) transmembrane"
                     /protein_id="ZP_02164449.1"
                     /db_xref="GI:163757360"
                     /translation="MSDTIVSQGWFTSLANPTRFLSLSGKILPFLAAAAVLTLVTGLY
                     MSFAAPEDYQQGITVRIMFIHVPAAWLAMMCYTVMAISSIGTLVWRHPLADVAAKTAA
                     PIGAAFTFLSLLTGSLWGRPMWGTWWVWDARLTSVFVLFLMYLGLMALHRAMDDPARA
                     ARPAAVLTLVGFINIPIIKFSVDWWNTLHQPASVIRLDGPTIHPSMLYPLLVMAIAYT
                     LIFFTLHLMAMRNEIWRRRVQTMRRQAAQSIGQGA"
     gene            complement(34878..35540)
                     /locus_tag="HPDFL43_18162"
     CDS             complement(34878..35540)
                     /locus_tag="HPDFL43_18162"
                     /note="COG2386 ABC-type transport system involved in
                     cytochrome c biogenesis, permease component"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter, membrane spanning protein
                     (heme)"
                     /protein_id="ZP_02164450.1"
                     /db_xref="GI:163757361"
                     /translation="MMALLKRDLAIATRSGGAAMLGVLFFLAVVAVIPFGIGPDLNML
                     ARIGPAILWIGALLASLLGLDRLFQADREDGSLDMLVMQDWFGLILTVFIKSSAHWLA
                     TGLPLVLAAPLLGLLMNMEAMATGAVMLTLLVGTPAISFIGAVGAAVAVALPRGGLLV
                     SILVLPLAIPILIFGVSASYAAVTDPDPFWPPFMILSAIALFFAALGPVAAAAALRGA
                     SD"
     gene            complement(35537..36187)
                     /locus_tag="HPDFL43_18167"
     CDS             complement(35537..36187)
                     /locus_tag="HPDFL43_18167"
                     /note="COG4133 ABC-type transport system involved in
                     cytochrome c biogenesis, ATPase component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative cytochrome c biogenesis ATP-binding
                     export protein"
                     /protein_id="ZP_02164451.1"
                     /db_xref="GI:163757362"
                     /translation="MRAIATNLAGRRGASLLFSGIGFSLTQGEALVITGPNGAGKSTL
                     LRVIAGLLDADSGHFALHGEDELALPVSEHAHYLGHRNAMKRELKVSENLEFWQRFQA
                     SETAEGLSVDAAIEAVGLTGVAHLPFGYLSAGQQRRIALARLLVSARPLWLLDEPTAA
                     LDKASDKLFADLVRAHLVQGGMAIAATHQPLGLEQVQTLELSGVHSTVADGQEAWA"
     gene            36473..39163
                     /locus_tag="HPDFL43_18172"
     CDS             36473..39163
                     /locus_tag="HPDFL43_18172"
                     /note="COG1048 Aconitase A"
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="ZP_02164452.1"
                     /db_xref="GI:163757363"
                     /translation="MAKSLDSFNCRSTLSVDGTDYTYYSLIEAEKNGLTGVAALPFSM
                     KVILENLLRNEDGRTVKKDDILAVAAWLTNKGKTEAEIAYRPARVLMQDFTGVPAVVD
                     LAAMRDAMVSLGGDPQKINPLVPVDLVIDHSVIVDEFGTPQALANNVAHEYERNGERY
                     RFLKWGQQAFKNFRVVPPGTGICHQVNLEYLGQTVWTREENGEITAYPDTCVGTDSHT
                     TMINGLGVLGWGVGGIEAEAAMLGQPISMLLPEVIGFRLTGKIKEGVTATDLVLTVVQ
                     MLRKKGVVSKFVEFFGPGLDSMSLADRATIGNMGPEYGATCGFFPVDGETINYLTMSG
                     REEDRIKLVEAYSKAQGMWREAGAADPVFTDTLDLDLGTVVPSMAGPKRPEGRIPLEG
                     IASGFATALESEYKKPGQLTNRYQVEGEDYDLGHGDVAIAAITSCTNTSNPSVLIGAG
                     LLARNALAKGLKTKPWVKTSLAPGSQVVAEYLAASGLQTDLDALGFNLVGFGCTTCIG
                     NSGPLPAPVSKTINDKGLIAAGVLSGNRNFEGRVSPDVQANYLASPPLVVAYALAGSV
                     QKDLTTEPIGDDKDGNPVYLKDIWPSSQEIQEFIMKYVTRALYASKYADVFKGDENWQ
                     AVEAPESQTYAWDDNSTYVQNPPYFAGMGKTGAGISDIVGARVLGLFGDKITTDHISP
                     AGSIKAQSPAGSYLMDNGVGVADFNQYGTRRGNHEVMMRGTFANIRLRNHMLGPNGRE
                     GGYTFHYPSREEVSIYDAAMQYKAEGVPLVIFAGVEYGNGSSRDWAAKGTNLLGVRAV
                     IAQSFERIHRSNLVGMGVIPFVFEEGSSWESLGLKGDEMVSIEGLADIKPGERKTAKV
                     TYGDGLVKDIPIICRIDTLDEVDYVNNGGILQTVLRDLAA"
     gene            39335..40111
                     /locus_tag="HPDFL43_18177"
     CDS             39335..40111
                     /locus_tag="HPDFL43_18177"
                     /note="COG5429 Uncharacterized secreted protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164453.1"
                     /db_xref="GI:163757364"
                     /translation="MDPNPMTARTLFHALALPLIAAMALAGPLRATAEAGDFIGVVEL
                     FTSQGCSSCPPADAELAKMADKGNVLALSYHVDYWNYLGWVDTLASKASTERQYGYAH
                     TLKRKNVYTPQAVVNGRDHANGADPAAVNALINKLSAIDEGLNVTVDAAYDNDGLTIS
                     IGEGEGKADIVVVYFDDSNTVDITRGENAGSTITYRHSVRDIETVGMWNGTAKSLTLP
                     ASVLSAKAGTGCAILLQVVGRDGSPGAILGAAMITSDETG"
     gene            40702..41097
                     /locus_tag="HPDFL43_18182"
     CDS             40702..41097
                     /locus_tag="HPDFL43_18182"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164454.1"
                     /db_xref="GI:163757365"
                     /translation="MTDGGDSSARRYTTGTETATTVDLAEIRRRNTPEPVTFHRRELD
                     LILRIYGRMVADGHWRDYAIDHLRDRAVFSAFRRTSEVPLYRIEKDPSRARKQGAFAI
                     ISAAGLVLKRGHELETVLRYFDKSPRVVR"
     gene            complement(41165..41713)
                     /locus_tag="HPDFL43_18187"
     CDS             complement(41165..41713)
                     /locus_tag="HPDFL43_18187"
                     /note="COG1247 Sortase and related acyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative phosphinothricin N-acetyltransferase
                     (antibiotic resistance) protein"
                     /protein_id="ZP_02164455.1"
                     /db_xref="GI:163757366"
                     /translation="MQIRDATLADVPAITRIYTESVRNGVASYELTPPGEAEMTRRFS
                     TICGNGYPYLVAEADGKVMGYAYASAFRTRPAYRWSVEDSIYLDPEARGRGYGKALLH
                     ALIAGCETLGFRQMIAVIGGAHPASIAVHQKAGFVHSGMISGSGHKHGSWLDTVFMQR
                     QLGEGKATDPDPEIYPGTLFMG"
     gene            complement(41838..42569)
                     /locus_tag="HPDFL43_18192"
     CDS             complement(41838..42569)
                     /locus_tag="HPDFL43_18192"
                     /note="COG0670 Integral membrane protein, interacts with
                     FtsH"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164456.1"
                     /db_xref="GI:163757367"
                     /translation="MADFRNSNVRVASGAHADAAIDEGLRAYMLRVYNIMAMGLGITG
                     VAAYGTYMLASTNPAFAQLLYASPLKWVIMLAPLAMVFFLSFRIEKMSVSAAQTTFWV
                     YAAMMGLSLSSIFIVFTGASITQTFFVTAASFGALSLYGYTTKKDLSGMGSFLIMGVF
                     GIIIAMVVNIFLQSSALEFAISAIGVLVFAGLTAYDTQQIKEMYYEGDGAATAGRKAI
                     MGALRLYLDFINLFMFLLQFLGNRE"
     gene            complement(42752..45307)
                     /locus_tag="HPDFL43_18197"
     CDS             complement(42752..45307)
                     /locus_tag="HPDFL43_18197"
                     /note="COG3127 Predicted ABC-type transport system
                     involved in lysophospholipase L1 biosynthesis, permease
                     component"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164457.1"
                     /db_xref="GI:163757368"
                     /translation="MAAPNQFRLGLAVRLALRELRGGLSGFYIFLACVALGTAAIAGV
                     NSVSQMMTGSIASEGRTILGGDIRFESENQPFSEAESSFIEDLGDVSTGANLRTMART
                     QDGSDQSLVELRAVDGAYPLYGSFQASPDMPLETIFEERDGVFGAATAQILLDRLGLS
                     LGDEVLVGQARFELRAIIVTEPDSLSEGFGFAPRFLISRSSLDAAGLIRPGSLIEYSY
                     RVRVDGGASAGQLANIRADLREQFPETGLEVRTSRNAAPALTRNIERFSQFLTLVGLT
                     ALIVGGVGIANSVRAWLDGKRGVIATLKCVGAPSRLVVAIYLIQVMLIAGFGVFLGLL
                     LGLATPFFAAGALSGVIPVAVQASVYPASLIIAAGFGLMTAFAFAVLPLGRAGEVPAT
                     ALFRQQSFEGGGLPRWPYLLAAGVTLVALCAAAIWFADDRGIASVFVAAVVVAFGVLR
                     LVGFAVQAIARKVPAVRSTPLRLAIGNIHRPGALTPSVVLSLGLGLALLVTLALIDTN
                     LRRELSGNLPDRAPNFFFVDIQSSEIDGFENILSEVAPEGKVIKVPMLRGRILELKGE
                     PVNEDNVPAEARWVLRGDRGVTYTKNLPENSRLSAGEWWAPDHQGEPLVSFSSEEAGE
                     LGLSVGDTITVSVLGRSIVARIANLRDVEWESLSINFVMVFSPNTFAGAPHSWMATLQ
                     DPDATAAEEGEVLRAVTQAYPTITSVRVKDALELANRVVGQIGIAIRAAALVALIASV
                     LVLAGALAAGNRSRIHDAVVLKTLGATRVTLIRAYVYEYGLLGLATAVFALAFGAVAS
                     WFVVSRIMTLPSSFMPDIAAATLVGALVVTVGIGLLGTWRVLGQKAAPVLREL"
     gene            complement(45307..45948)
                     /locus_tag="HPDFL43_18202"
     CDS             complement(45307..45948)
                     /locus_tag="HPDFL43_18202"
                     /note="COG4181 Predicted ABC-type transport system
                     involved in lysophospholipase L1 biosynthesis, ATPase
                     component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative atp-binding abc transporter protein"
                     /protein_id="ZP_02164458.1"
                     /db_xref="GI:163757369"
                     /translation="MLKGIDLDIAKGQSVGIVGPSGSGKSTLLMVVAGLERLDSGEVH
                     IAGSALHTLSEDAVAAVRGRSVGIVFQSFHLIPNMTALENVAVPLELAGKSDAFDRAR
                     EELIAVGLGERLTHYPGQLSGGEQQRVAIARALAPDPALIVADEPTGNLDGDTGRQIA
                     ELLFAKQSERGATLLLVTHDPALASQCDRQVSVRSGLIVGDSAGADAAEKAIA"
     gene            46119..46760
                     /locus_tag="HPDFL43_18207"
     CDS             46119..46760
                     /locus_tag="HPDFL43_18207"
                     /note="COG2755 Lysophospholipase L1 and related esterases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-coa thioesterase i protein"
                     /protein_id="ZP_02164459.1"
                     /db_xref="GI:163757370"
                     /translation="MRFRNLIAAALATLSFIATPLSARADEVIRLVGFGDSLMAGYNL
                     DSAEGFPARLQAALVEKGYQVEITDAGVSGDTTSGGLARLDWSIPEGVDGVILELGAN
                     DALRGLPPETTRENLDAMITRLKERGIAVLLAGMLAPPNMGADYEAKFNTIYPDLAKK
                     HDVVFYPFFLDGVTGNPSLLLSDGMHPNANGINRMVEGILPYAETFLTGLKAL"
     gene            46857..47447
                     /locus_tag="HPDFL43_18212"
     CDS             46857..47447
                     /locus_tag="HPDFL43_18212"
                     /note="COG1514 2'-5' RNA ligase"
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase"
                     /protein_id="ZP_02164460.1"
                     /db_xref="GI:163757371"
                     /translation="MPRLFTALEIPRDAALSLSLLRGGLPGARWLDVENYHITLRFIG
                     DVDGPTADEVVNALDRVDRPSFSLSLSGIGSFGAKKPHSIWAGVSACSELMALQAEIE
                     RICQRIGLAPDTRRFSPHVTLARLRHARVSDVVSYLSGRGDFRTESFDVGRFVVMSAR
                     DSVGGGPYLVEEAYPLGWRNSVPSLSSSAWQPSRSN"
     gene            complement(47375..47833)
                     /locus_tag="HPDFL43_18217"
     CDS             complement(47375..47833)
                     /locus_tag="HPDFL43_18217"
                     /note="COG0394 Protein-tyrosine-phosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="probable tyrosine phosphatase protein"
                     /protein_id="ZP_02164461.1"
                     /db_xref="GI:163757372"
                     /translation="MGNICRSPLAEGIFRKGLADAGLDGFVMVDSAGTGNWHAGDPPD
                     IRSVETATENGIDISMQRARQVSDDDYDRFDLIFAMDRSNEATLKARAPSSQHDRIHL
                     FLDHTLGMRTDVPDPYYGGVDGFDAVYQLLREGCQALLDRLGTELRQPKG"
     gene            47928..48233
                     /locus_tag="HPDFL43_18222"
     CDS             47928..48233
                     /locus_tag="HPDFL43_18222"
                     /note="COG2154 Pterin-4a-carbinolamine dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional coactivator/pterin dehydratase"
                     /protein_id="ZP_02164462.1"
                     /db_xref="GI:163757373"
                     /translation="MSRPKLDSTTISQKLAAVSQWNIDAGETALTRSFKFKDFSEAFG
                     FMARAALVAEKLDHHPEWKNVYRTVEVRLTTHDAGGLTQLDFDLAGAMDTIAASTGQ"
     gene            48335..48733
                     /locus_tag="HPDFL43_18227"
     CDS             48335..48733
                     /locus_tag="HPDFL43_18227"
                     /note="COG3339 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164463.1"
                     /db_xref="GI:163757374"
                     /translation="MNALEGEILEPDEKIRNGENDRADEESVRTGFWKTFGKAARQLP
                     FAEDLVAAYFCALDPETPGKAKAVMLGALAYFIMPLDTIPDFLAVVGFSDDIAVLTLA
                     IATVRSNMTDAHRAAARKALADFSPDKTSD"
     gene            complement(48775..49350)
                     /locus_tag="HPDFL43_18232"
     CDS             complement(48775..49350)
                     /locus_tag="HPDFL43_18232"
                     /note="COG1595 DNA-directed RNA polymerase specialized
                     sigma subunit, sigma24 homolog"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ECF RNA polymerase sigma-70 family
                     protein"
                     /protein_id="ZP_02164464.1"
                     /db_xref="GI:163757375"
                     /translation="MSGDLKERFARLAEAVAVRRDQKAFGELFDYFAPRLKSYLQRLG
                     MESSQAEEMTQEVMIVLWHKASLFDSSKSSLGTWLFRIARNRRIDALRRDRSGLLDPE
                     DPALHPSQPEAADDIVEAEERDERVRQAMLDLPEEQATLVRQAFFLGRSHSQIAEDTG
                     LPLGTVKSRIRLAFARLRRTLESGDGDVTFH"
     gene            49646..50149
                     /locus_tag="HPDFL43_18237"
     CDS             49646..50149
                     /locus_tag="HPDFL43_18237"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164465.1"
                     /db_xref="GI:163757376"
                     /translation="MLGKTIATVLTGLFALTAAAWAQSPNRIEQFDAWGAYSYDSAGG
                     KVCYVLSVPISSAPTNVNHGDIFFLISQRPGQNVSYEPQAMMGYPLKEASKINVNIDG
                     RNFVLFSRGNSGWVENAAEEPQLVAAMKAGSDMTVKAVSRRGTDTSYSYSLRGVTAAL
                     NKIATCQ"
     gene            50314..50874
                     /locus_tag="HPDFL43_18242"
     CDS             50314..50874
                     /locus_tag="HPDFL43_18242"
                     /note="COG1309 Transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164466.1"
                     /db_xref="GI:163757377"
                     /translation="MAPKHSLTPDDWIKTAFRLLADAGPRAIRVDLMCKALGVTKGSF
                     YWHFDDLAALKAAMIERWRQAAARDLIASATQTELAPRDLIIGLFEEVQKRQAKGGAL
                     AETALRQWAGADPAVLKLVREADNERLAFLTTQMRAAGLTGGEARSRAAFVYAALIGM
                     EQLAGEPALTPSNMAGIIDAALTPGV"
     gene            complement(50934..51671)
                     /locus_tag="HPDFL43_18247"
     CDS             complement(50934..51671)
                     /locus_tag="HPDFL43_18247"
                     /note="COG2378 Predicted transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164467.1"
                     /db_xref="GI:163757378"
                     /translation="MSAALIPADDGILAMRRSDRLFEIIQILRSARQPVTAEVIARQL
                     EVSTRTIYRDISALQIMKTPIEGESGIGYIMRRGYDLPPLNFDLEEIEALRVGLALLS
                     RTGDSALQGAARRIHEKVDALHGPADWLQVAPWGAALDDPAKGCVSKATLRDAIRDER
                     KLELIYQDEKGCETVRTVRPLALVYHLECVMLAAWCELRGAFRHFRADRIYGCDVLEE
                     RFTGQAGALRMIWLEQNPLGTAEVEQV"
     gene            51722..52027
                     /locus_tag="HPDFL43_18252"
     CDS             51722..52027
                     /locus_tag="HPDFL43_18252"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164468.1"
                     /db_xref="GI:163757379"
                     /translation="METGDRTMSYYDHATMIAHRLGPWQQQPEPPFDVPARHRKRRPD
                     RLAKGERSPAACDPETGDHEDRGRQPPSNTGWRGMLASVAGLLPLAQCRGLSRRGKA"
     gene            52102..53334
                     /locus_tag="HPDFL43_18257"
     CDS             52102..53334
                     /locus_tag="HPDFL43_18257"
                     /note="COG0820 Predicted Fe-S-cluster redox enzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM enzyme, Cfr family protein"
                     /protein_id="ZP_02164469.1"
                     /db_xref="GI:163757380"
                     /translation="MPATLDLTDPSARPVRPAAIAADGKPVLVGMDRDELIAAMAEAG
                     VPERQRKMRVNQLWHWLYVRGSSDFADMHTISKDLRDKLDAHFSVARPEIVEEQISSD
                     GTRKWLMRFPPRGAGRPVEVETVYIPEEGRGTLCISSQVGCTLTCTFCHTGTQKLVRN
                     LTPEEILAQLLVARDRLGDFPHKDTPQGAIVPTEGRKVTNIVMMGMGEPLYNFENVKK
                     ALLIASDGDGLALSRRRITLSTSGVVPEITRTGTEIGVMLAISLHAVRDELRDELVPI
                     NKKYPLKQLLDACRAYPGLSNARRITFEYVMLKGVNDSLSDAKELVRLLKGIPAKINL
                     IPFNPWPGSAYECSDWDTIETFADFINANGYASPIRTPRGRDILAACGQLKSESERMR
                     KTERLALEAMMIAGHGAD"
     gene            53344..53835
                     /locus_tag="HPDFL43_18262"
     CDS             53344..53835
                     /locus_tag="HPDFL43_18262"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164470.1"
                     /db_xref="GI:163757381"
                     /translation="MADILRPIIRMFVITLGFFAAFLAAGTAFVFLARLVVPEDFGRI
                     DELELTVTLAVGILGVSSLFARALLLPAFAVIAGFEFFKLRDWLSHALAGGLLALAAA
                     SLPLAGTADAANAGNPAWDIAIRIACGIIGATLYWLIAGRNAGRWLPSERAKANETGD
                     IEA"
     gene            complement(53836..54483)
                     /locus_tag="HPDFL43_18267"
     CDS             complement(53836..54483)
                     /locus_tag="HPDFL43_18267"
                     /note="COG1280 Putative threonine efflux protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RhtB family transporter"
                     /protein_id="ZP_02164471.1"
                     /db_xref="GI:163757382"
                     /translation="MLSDFIPGLPVLAAFSLAVLLLAITPGPDMTLWMSRAIRDGKAI
                     GMMAMLGTNLGIVIHTLLVAFGISALVVASPVAFLVLKTGGAGYLLWLAIQAVRNRSV
                     LAVEATGKNDASYFKAFLNGFWVNLLNPKVIIFFMTFLPQFVSVNDPHVTGKLIFLGV
                     LSIIIALPVAIVVVLGANGLSAWLKRKPQVMRVVDYVFAAVFSVFAVRILLTQSR"
     gene            complement(54546..55358)
                     /locus_tag="HPDFL43_18272"
     CDS             complement(54546..55358)
                     /locus_tag="HPDFL43_18272"
                     /note="COG0366 Glycosidases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164472.1"
                     /db_xref="GI:163757383"
                     /translation="MSTLFAWVVPAYSSGSPVDHTWITTYDSRKHAYPDIAAVKKAKE
                     ANWYCWGSFHPKGGVPGNPPGFIGSKTGDRSIADCLVLPNASSKTNTAARGTIFSYGI
                     DGVCHQLANQVLYATKAAGSLPMTVKAARGYAISTFLYGTYGLQHAAWKAKLMACAGA
                     KPMTKLPSAMEERVEHLPDDFADHARQVLSDKPELLDQLLALRTEVNTFAAQKIPGFF
                     PPDAALLNARNQHLLDQAAALLSPDEFHQIFGMEPGARIDIVDPTIMEQLDE"
     gene            complement(55424..56278)
                     /locus_tag="HPDFL43_18277"
     CDS             complement(55424..56278)
                     /locus_tag="HPDFL43_18277"
                     /note="COG1028 Dehydrogenases with different specificities
                     (related to short-chain alcohol dehydrogenases)"
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase protein"
                     /protein_id="ZP_02164473.1"
                     /db_xref="GI:163757384"
                     /translation="MADLQSILGDGKVAVVTGAASGIGLAAATRFAARGMAVVLVDND
                     QGKLADAREIVAAQSKNADARIAAVATDVSDREAVAALEQTVAGQFGDVHVLMNNAGI
                     QPGSSLFGLEENWERVLNVNLMGIIHGTRLFGPKMIAHGEPAMIINTGSKQGITTPPG
                     DPAYNVAKAGVKAFTEALQHELRNTAGCQVNAHLLIPGFVYTPLTARGRTEKPGGAWT
                     PEQTVDFMMESLERGDFYILCPDNDVDRATDEKRIAWAAGDIIENRPPLSRWHPDCAA
                     DFDAYLKK"
     gene            56477..57706
                     /locus_tag="HPDFL43_18282"
     CDS             56477..57706
                     /locus_tag="HPDFL43_18282"
                     /EC_number="6.3.4.5"
                     /note="COG0137 Argininosuccinate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="ZP_02164474.1"
                     /db_xref="GI:163757385"
                     /translation="MATHKDVKKVVLAYSGGLDTSIILKWLQTELGAEVVTFTADLGQ
                     GDELGPARKKAELMGIPDKNIYIEDVREEFVRDFVFPMFRANAVYEGVYLLGTSIARP
                     LISKRLVEIAEETGADAIAHGATGKGNDQVRFELSAYALNPDIKVIAPWRDWTLKSRT
                     ELIAFAEAHQIPIPKDKRGEAPFSVDANLLHSSSEGKVLEDPNEEAPEYVYQRSVSPE
                     DAPDKATEIEIGFKAGDAVSINGETLSPATILARLNDLGRDNGIGRLDLVENRFVGMK
                     SRGVYETPGGTILLTAHRAMESITLDRGAAHLKDELMPRYAELIYNGFWFSPEREMLQ
                     AAIDHSQREVEGTVRLKLYKGNVIVTGRASPKSLYDDALVTFEDDRGAYDQKDAAGFI
                     RLNALRLRTLAARNRNS"
     gene            57861..59912
                     /locus_tag="HPDFL43_18287"
     CDS             57861..59912
                     /locus_tag="HPDFL43_18287"
                     /note="COG0339 Zn-dependent oligopeptidases"
                     /codon_start=1
                     /transl_table=11
                     /product="probable peptidyl-dipeptidase a protein"
                     /protein_id="ZP_02164475.1"
                     /db_xref="GI:163757386"
                     /translation="MTQSAAPIFDWTAPLGLPEFQAIADEDFKPAFELGFAEHDAEID
                     AIAKNPAAPDFDNTMVALELAGDKLSRVSSLFWNRAGTDTNDAIQALEREIAPQMSRH
                     YSKIAMNRDLFARVDELYRNRHDLGLTEEQDRLLERIWKSFIKSGAGLDPEGQARLAE
                     IGEKLAGLGARFGQNVLADEKDWLLLLDDGADLDGLSDDLRAAMAAVAEELGHKGKFA
                     VTLSRSIIEPFLTSSARRDLREQAFRAWTARGANGGETDNSALISEIIALRTEKAELL
                     GYESYAALKLDNTMAKTPDAVEALLGDVWTRAVERAEADKLDLAGLIGEEGGNHDVAA
                     WDWRYYAERLKARKFDFSEAELKPYLSLDKMIDACFDVAHRLFGITMIPRPDIKGPHP
                     DARVFEVKDRNGAPLATFVADYFARPSKRSGAWMSGMQSQHKLPMPDGSLGEKPIITN
                     VMNFAKPAAGQQALLSLDDARTLFHEFGHALHGMLSDVTYPSLSGTSVSRDFVELPSQ
                     LFEHWLTVPEILEKHARHCKTGEPIPRALLDKVLSAQTFDAGFGAVEFTASALVDMAW
                     HTGGAKADPATFEAETLKKLGLPVAIVMRHASPHFLHVFAGEGYSAGYYSYMWSEVLD
                     ADAFAAFEETGDPFNPEMAEKLRANIYSAGGSRDPAELYKAFRGRMPDPTAMLEKRGL
                     A"
     gene            complement(59962..60543)
                     /locus_tag="HPDFL43_18292"
     CDS             complement(59962..60543)
                     /locus_tag="HPDFL43_18292"
                     /note="COG0346 Lactoylglutathione lyase and related
                     lyases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164476.1"
                     /db_xref="GI:163757387"
                     /translation="MRKLQAQGIHHITLVGADRQTSIDFWEGVLGMPFVFEQPNLDSA
                     LESHLYFDPGDGRLITIFTSEDRKPDPERTSTEPGAVHHLAINVSKATFSQAVERLDE
                     RGIKHSGVKDRGFMDSIYFTDPLGFLIELAAYRFEPPAGSSHAEVLLEAHKIRVAKGD
                     YNIAEVHLADAIEAIILRSQQSLSDDRTPKQAY"
     gene            60737..61159
                     /locus_tag="HPDFL43_18297"
     CDS             60737..61159
                     /locus_tag="HPDFL43_18297"
                     /note="COG4319 Ketosteroid isomerase homolog"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164477.1"
                     /db_xref="GI:163757388"
                     /translation="MASALAAGAAAGEPEAGQKAILNTIATMTSSFAAGDLDGVLTTY
                     EEGAAVVSAPGQPVRGREELAVMFGQFIEAGIDFDYGTHDVVIAGDIGLHLMKWTSAT
                     PDGQQSALSVAVLRRQPDGNWRMVIDHPFGDHVMVDGN"
     gene            61445..63271
                     /locus_tag="HPDFL43_18302"
     CDS             61445..63271
                     /locus_tag="HPDFL43_18302"
                     /note="COG1217 Predicted membrane GTPase involved in
                     stress response"
                     /codon_start=1
                     /transl_table=11
                     /product="probable gtp-binding protein (tyrosine
                     phosphorylated protein a)"
                     /protein_id="ZP_02164478.1"
                     /db_xref="GI:163757389"
                     /translation="MSLRNIAIIAHVDHGKTTLVDELLKQSGVYRENERVQERAMDSG
                     DIEKERGITILAKATSVEWKGTRINIVDTPGHADFGGEVERILSMVDGAIVLVDAAEG
                     PMPQTKFVVGKALKVGLRPIVAINKIDRPDARVDEVINEVFDLFAALDATDEQLDFPI
                     MYGSGRNGWMDAGPDRPADGGSLTPLFDLVLEHCPEPTVAEGPFRMIGTILEANPFLG
                     RIITGRIHSGSIKPNQAVKVLNGEGKLVENGRISKILAFRGLERQPVEEAHAGDIVAI
                     AGLSKGTVADTFCDPSVAEALTAQPIDPPTVTMTFLVNDSPLAGTEGDKVTSRVIRDR
                     LLKEAEGNVALKIEESEGKDSFYVSGRGELQLAVLIETMRREGFELAVSRPRVVMHND
                     ESGTLMEPIEEVVIDVDEEHSGVVVQKMSERKAEMTELRPSGGNRVRLVFHAPTRGLI
                     GYQSELLTDTRGTAVMNRLFHDYQPYKGEIGGRTNGVLLANQPGEAVAYAMFNLEDRG
                     PMIIEPGDKVYMGMIIGIHTRDNDLEVNVLKGKQLTNIRSAGKDEAVKLTPPIRMTLD
                     RALSWIQDDELMEVTPKSIRLRKRYLDANDRKRFAKAGASAA"
     gene            63273..63932
                     /locus_tag="HPDFL43_18307"
     CDS             63273..63932
                     /locus_tag="HPDFL43_18307"
                     /note="COG4845 Chloramphenicol O-acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase"
                     /protein_id="ZP_02164479.1"
                     /db_xref="GI:163757390"
                     /translation="MAEAREVDLESWSRAGQFNLFRSYDRPHFATTARVDVTALMTKG
                     KSAGASPYRAFIHAIGAGVHAVPALKMRFIGDQVFEYGAIALSATVPRPGDTFGYAYI
                     PYIADWAEFDHSCKAIIEETARGTDFGANTGQRFDLAYLSCLPWIDFTALDNALPGPD
                     DCIPRFSWGKIVQGHDGRWSCPVAVQVHHALVDGLQVGQFFQAAQACLDQFADTNTDT
                     A"
     gene            64136..64645
                     /locus_tag="HPDFL43_18312"
     CDS             64136..64645
                     /locus_tag="HPDFL43_18312"
                     /note="COG0454 Histone acetyltransferase HPA2 and related
                     acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyltransferase"
                     /protein_id="ZP_02164480.1"
                     /db_xref="GI:163757391"
                     /translation="MSKTLTIDIRHAEPQDAEAIAEAHRAAWSHAYTGILPHKALRQM
                     LERRNVAWWRRAIRGSTSILVLDVGGTIAGYATLGLNRARSLPQEGEIYELYLRPEFQ
                     GVGLGKRLFNEARQLLTSLGCKGMAIWCLEENHQSVDFYRFQGGRDVAEGHETFDGKT
                     LKKIAFIWA"
     gene            64863..65396
                     /locus_tag="HPDFL43_18317"
     CDS             64863..65396
                     /locus_tag="HPDFL43_18317"
                     /EC_number="3.6.1.1"
                     /note="COG0221 Inorganic pyrophosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic pyrophosphatase"
                     /protein_id="ZP_02164481.1"
                     /db_xref="GI:163757392"
                     /translation="MRIDAITIGEKPPHDVNVIIEVPVGGHPIKYEMDKDAGTLVVDR
                     FLYTPMTYPGNYGFVPHTLSDDGDPIDVLVCNTRPLIPGCVINVRPIGVLIMEDNSGQ
                     DEKIIAVPSAHLTKRYEGVNDYTDMPEITLQQIEHFFEHYKDLEPGKWVKIGGWRDAE
                     VARKLIVEAIDRAKAKG"
     gene            complement(65447..65638)
                     /locus_tag="HPDFL43_18322"
     CDS             complement(65447..65638)
                     /locus_tag="HPDFL43_18322"
                     /note="COG1872 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164482.1"
                     /db_xref="GI:163757393"
                     /translation="MKIRVRAVAENNKANRALEAFLAKRLKLAKSRVRVISGANSRTK
                     TVRLEGDPQELAAKLDGLA"
     gene            complement(65752..66045)
                     /locus_tag="HPDFL43_18327"
     CDS             complement(65752..66045)
                     /locus_tag="HPDFL43_18327"
                     /note="COG0762 Predicted integral membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164483.1"
                     /db_xref="GI:163757394"
                     /translation="MIAVFQTIDLALGIYTWIIIGSAIFSWLYAFNVINANNRFVGMI
                     GEFLYKATEPALRPIRRILPDLGGLDISPIVLLIAIFFVRTFIATSIAPIFLR"
     gene            66325..67626
                     /locus_tag="HPDFL43_18332"
     CDS             66325..67626
                     /locus_tag="HPDFL43_18332"
                     /note="COG0477 Permeases of the major facilitator
                     superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transport transmembrane protein"
                     /protein_id="ZP_02164484.1"
                     /db_xref="GI:163757395"
                     /translation="MQIPLHAEDRFAAFRHRAFAFYFIARFLSTFGLQIISVSVGWQI
                     YDLTRDPFDLGLVGLIQFMPALVLILFTGSAADRYGRRTIMMICEVIIGLCALALVYF
                     AWKGLVSPLPIFAVLLVIGISRAFFAPASQSLAPNLVPARDLPNAIAWNSTSWQTATI
                     VGPVAGGLLYGLGPMTPYLTAVGFFALATVFITLVPPPSQRSRGQAQSWDTLMAGFSY
                     VRNQKIVLGAISLDMFAVLLGGAIALMPVFARDVLELGPTGLGWLRAAPGIGAIGMAI
                     YLASRPVKRHAGRAMFIAVGVFGAATMIFGLSTSPLLSIAALIVMGASDMISVYVRQS
                     LVQLWTPDELRGRVSAVNMVFIGASNELGEFRAGTMAALIGPVAAVVIGGAGTLAVAL
                     AWSFGFPALRQIQSLDKDAEESRATLRAELERQEKSGPGTA"
     gene            complement(67577..68314)
                     /locus_tag="HPDFL43_18337"
     CDS             complement(67577..68314)
                     /locus_tag="HPDFL43_18337"
                     /EC_number="6.3.5.2"
                     /note="COG0518 GMP synthase - Glutamine amidotransferase
                     domain"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="ZP_02164485.1"
                     /db_xref="GI:163757396"
                     /translation="MRVTGFELRAGSRSGRILIILHQETSSSGRVGQILDRMGYEADV
                     RRPVLGDPLPDHLDDHAGVVVFGGPMSANDDDEGVRRETRFMDVILKSDKPYLGICLG
                     AQILVNHLGGRVATRDDGQVEIGWYGLEATPAGQTMMDWPPMVYQFHREGFDLPRGAA
                     LLATAETYPNQAFRYGDNAWGIQFHAELTLAMMHRWAVRGAHRFDLPGAQQGRQHLDG
                     RLVHDAALLDWLKRFLDRIFPAVPTLP"
     gene            complement(68295..68783)
                     /locus_tag="HPDFL43_18342"
     CDS             complement(68295..68783)
                     /locus_tag="HPDFL43_18342"
                     /note="COG4103 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164486.1"
                     /db_xref="GI:163757397"
                     /translation="MLEQIRAFLSNLQGDNQRSGPDASDPDVAAVALFYHVIGADGVV
                     DEAEAEALKTMIAEEYADSGNSAKVLLEAGEAADRESVDLYSFTSVLNRSLDPEAKVH
                     FIELLWRLAYADGHRHELEDHVVWRISDLMGVSSRDRVLARQRALKDAGIHGGEHESD
                     GV"
     gene            complement(68805..70700)
                     /locus_tag="HPDFL43_18347"
     CDS             complement(68805..70700)
                     /locus_tag="HPDFL43_18347"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164487.1"
                     /db_xref="GI:163757398"
                     /translation="MMIRLLFFVALVLVLGFGFAWLADRPGDLSIVWQDRRIEMSLMT
                     AVTVMVSLVAAVMITWWLIRTIWLSPRLVSRYFRANKRDRGYQALSTGLLAAGAGDAM
                     TARKMNKRSRGLLSADQEPLIHLLDVQTALIEGRNDDARKQFEALAEDPETRLLGLRG
                     LYLEAQRQGATEAAHHYAEKAAELAPHLPWAGAAALSFRTQEGKWDEALRLLDTQRQA
                     GTLEALEADRKKAVLLTARARDRLDADPLRSRDDALAALKVAPGFAPAAVIATKALLR
                     NDNLRKAARILESAWKVNPHPEIADAYVRARIGDTAADRLKRAERLEKLKPLNAQAYD
                     TVARAALEARRFDLARQKAEASARLLPCEGIYLLLADIEEAETGDEGRVRHWLSQAVR
                     APRDPAWTADGYVSETWEPVSPVTGKLDAFEWKVPVEQLSGPRYDADMPEKSFDRAMA
                     SLPPVREVAEPAAPSGPVVNPEPEALVEVAAAEAVTVVAPEAPAGALADPVAGALAPV
                     AKIDDIPHPMPTPIADADPLLENEALKNAAKADDQPGGRVDAAADDKAGSTKSQDPAG
                     ESGNGGGNGKAAAATKPEPQSEPETKLDPEEEARAREAAFLTHRPDDPGVDENAEPEK
                     PGRFRLF"
     gene            complement(70708..72306)
                     /locus_tag="HPDFL43_18352"
     CDS             complement(70708..72306)
                     /locus_tag="HPDFL43_18352"
                     /note="COG0840 Methyl-accepting chemotaxis protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164488.1"
                     /db_xref="GI:163757399"
                     /translation="MRNTWPPPPDPSGDAMSKGPTPRHSKSPKPLTIDLDAKDVTPQS
                     ASSAETKPATDKAKPAGKPAEAALSTSSGSTPKVSAAGATKPATKTETATDKKPAGPG
                     AKPASADVGTSSTAKSGPSASVAQGNASKSTPDQAQTQGEPQAKAQAQAETKRSEPKP
                     AQTAPANRGGGLGLVASGLIGAIIALGGGYGLQTSGLLPVPVVSSDSADQVQSLASRV
                     DGLAGTVDQLSADLSALPSDDGSSLTTELQARLASLEAAIAGGAAAPGDGATVDLGLL
                     TARLDALEASIAALAESAGDASADPELAAAVTELKAGQSGVNAAVSELQSQSAALRES
                     VAGLEQRQATLEGQLDEPSRQIDLARAIAASGLKTAIDRGGPFMSELEAFASVAPDDP
                     AVSEFRDLAARGVPSRSDLMEAFPDAANRAIAAANPIDPDAGLVDRLMSSALSVVKVR
                     PVGEVEGDTADAIVARTEARLLDGNLDAALSEWNTLPQAALAATSDFGDSLAARARAE
                     KLIASSLTGGALPAAPASSQAPAN"
     gene            complement(72343..73074)
                     /locus_tag="HPDFL43_18357"
     CDS             complement(72343..73074)
                     /locus_tag="HPDFL43_18357"
                     /EC_number="4.2.1.75"
                     /note="COG1587 Uroporphyrinogen-III synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthetase"
                     /protein_id="ZP_02164489.1"
                     /db_xref="GI:163757400"
                     /translation="MRVLVTRPEPGASRTASRLRTLGHEPVILPLFEAQITARPDDLP
                     PVQQVGGLIATSARAFSIFGSNTAPAEYLHFPVYTVGPATAQAARDAGFHDVHEGAGS
                     ARDLAGALTAQSGTAVDGPGLLYLAGSPRKPFLEEALTAEGLPLKVLETYRMDQLSYP
                     TDSQILDLLSPAPDAALFYSSNAALGFCSLVSTKNLDKSLQSTFFMCLSPEISSAFPE
                     TWMARVISAGHPDEDSLLASLAGLG"
     gene            complement(73085..74023)
                     /gene="hemC"
                     /locus_tag="HPDFL43_18362"
     CDS             complement(73085..74023)
                     /gene="hemC"
                     /locus_tag="HPDFL43_18362"
                     /EC_number="2.5.1.61"
                     /note="COG0181 Porphobilinogen deaminase"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen deaminase"
                     /protein_id="ZP_02164490.1"
                     /db_xref="GI:163757401"
                     /translation="MDVSQMKPYRIGTRGSPLALAQAHETRERLMAAHDLPESAFEIV
                     VLSTKGDRITDRPLAEIGGKGLFTEELEEQLSDGRLDLAVHSSKDMPTALPEGLGIVT
                     YLEREDPRDAYISSAAPRLEDLPQKAVVGSSSLRRQALIRRLRPDISVITFRGLVDTR
                     LRKLADGEVHATMLAFAGLKRLGKSEVVTNLMDPESFPPAPGQGAICIEARLDDERIA
                     ELLAPIDHADTHAALNCERGFLGALDGSCRTPIAGHATLENGQVSFYGMILTPDGTTF
                     HDIRVQGPAADAAQLGADAGAEVRARAGSKFFESWS"
     gene            74199..75293
                     /locus_tag="HPDFL43_18367"
     CDS             74199..75293
                     /locus_tag="HPDFL43_18367"
                     /note="COG0533 Metal-dependent proteases with possible
                     chaperone activity"
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="ZP_02164491.1"
                     /db_xref="GI:163757402"
                     /translation="MNRSLNILGIETSCDETAASIVCRAPDGSGEILSDVVLSQLDVH
                     AAFGGVVPELAARSHVSTLDRLIKQALEQSKMTLDDIDAVAVTAGPGLIGGLMVGLMT
                     GKAIAMAAGKPFYGINHLEGHALTARLTDKIAFPYLLLLVSGGHTQIVLVEGVDHYER
                     WGTTIDDALGEAFDKTAKLLGLPYPGGPAVEQAAQSGEPGRFKLPVPMRRDPRLVFSF
                     SGLKTAVRQMAEHETPLSKQTIADLCLAFQTAVTASLDDRISMALERFKARFPECQDP
                     ALVVAGGVAANKAIRSSLLARTQSAGFHFIAPPLNLCTDNAAMIAWAGAERMAQGLPP
                     SPLDLAPRSRWPLDAEAIAAIGHGKRGAKA"
     gene            75422..75715
                     /locus_tag="HPDFL43_18372"
     CDS             75422..75715
                     /locus_tag="HPDFL43_18372"
                     /note="COG2350 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164492.1"
                     /db_xref="GI:163757403"
                     /translation="MLYALMCKDKPASLDKRMAERPAHVEFLKDLEAQGILKMAGPLL
                     GEDEKPIGSLVVIAADDMAAAEALAARDPYAIAGLFDTVEIRAFNWVFKNPEA"
     gene            75717..76145
                     /locus_tag="HPDFL43_18377"
     CDS             75717..76145
                     /locus_tag="HPDFL43_18377"
                     /note="COG2947 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164493.1"
                     /db_xref="GI:163757404"
                     /translation="MAYWLFKSEPFKWSWDMQKAKGSEGEQWDGIRNYQARNNMRAMK
                     LGEKGFFYHSNEGLEVVGIVEVSALIHPDTTTDDPRWECVDIRAVCDMPKPVTLKDVK
                     ANPKLAEMSLVTSMRLSVQPVTEAEYLEVCRMGGLDNPPR"
     gene            76177..76824
                     /locus_tag="HPDFL43_18382"
     CDS             76177..76824
                     /locus_tag="HPDFL43_18382"
                     /note="COG3897 Predicted methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164494.1"
                     /db_xref="GI:163757405"
                     /translation="MKTDPEHFILANTALGTPPHVPEIRLHLADEAHDLWLKTEDELE
                     EIGLPPPFWAFAWAGGQGLARHILDNPDLVAGKSVLDFATGSGLVAIAACLGGATPVN
                     AVDIDPWSATATRLNAEANKVGFKITQSNLVGTDAGWDVVLAGDVFYDQAMSALIQPW
                     FSDLAKRGALVLVGDPGRAYCPKDRLELLATYMVPVTRALEDNEIKRTSVFRFTG"
     gene            complement(76947..77456)
                     /locus_tag="HPDFL43_18387"
     CDS             complement(76947..77456)
                     /locus_tag="HPDFL43_18387"
                     /note="COG3786 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical Cytosolic Protein"
                     /protein_id="ZP_02164495.1"
                     /db_xref="GI:163757406"
                     /translation="MIVVRRSPLDPLQAIVRCGPLLFQAALGRGGTGSRKREGDGVTP
                     RAQMRVLAGFRRGGLLTPDHCGIGLLRAGSKDGWCDAPGHGAYNRHVRLPFRASHETL
                     IRDDVLYDFGFVLDWNIVSRRRGAGSAIFLHVAKPGFPPTQGCVALKRRDLLTLMPHI
                     RRGTSVRVL"
     gene            77659..78342
                     /locus_tag="HPDFL43_18392"
     CDS             77659..78342
                     /locus_tag="HPDFL43_18392"
                     /note="COG0745 Response regulators consisting of a
                     CheY-like receiver domain and a winged-helix DNA-binding
                     domain"
                     /codon_start=1
                     /transl_table=11
                     /product="putative two-component response regulator
                     protein"
                     /protein_id="ZP_02164496.1"
                     /db_xref="GI:163757407"
                     /translation="MTARSILLVDDDEDLRETLVEQLSLYEEFAILQEASATKGVQTA
                     RNNHIDLLIMDVGLPDMDGREAVKLLRKGGFKSPIIMLTGHDTDSDTILGLEAGANDY
                     VTKPFRFAVLLARIRAQLRQHEQSEDATFTVGPYTFKPSQKLLLDDKGGKIRLTEKEA
                     AIIRYLYRADQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIEADPSNAEILVT
                     ESGGYKIIP"
     gene            78385..78846
                     /locus_tag="HPDFL43_18397"
     CDS             78385..78846
                     /locus_tag="HPDFL43_18397"
                     /note="COG0664 cAMP-binding proteins - catabolite gene
                     activator and regulatory subunit of cAMP-dependent protein
                     kinases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164497.1"
                     /db_xref="GI:163757408"
                     /translation="MALNDDIDLLSTVSLFSDIGEDKLRLIAFGAERRKLQAGQMLFR
                     ENTAADCAFVVADGRIELSRTAHNGQSETSGTVGRGTLLGELAMVTAVDRSMTAIAVD
                     AAEVIRINRPLFRRMLEEYPEIADVVRQRISADLADLNKGLSKVADRFAGE"
     gene            complement(78892..79704)
                     /locus_tag="HPDFL43_18402"
     CDS             complement(78892..79704)
                     /locus_tag="HPDFL43_18402"
                     /note="COG0708 Exonuclease III"
                     /codon_start=1
                     /transl_table=11
                     /product="putative exodeoxyribonuclease iii protein"
                     /protein_id="ZP_02164498.1"
                     /db_xref="GI:163757409"
                     /translation="MAFSVTTWNINSVRLRLPLVQHLLETVQPDVLCLQETKCPNDAF
                     PSAAFRKIGYEHMAIHGQKGYHGVAILSRLPLSDDQRLSYCGIADARHVSAVVEAPGE
                     RRIRLHNFYVPAGGDEPNRDINPKFGHKLDFIEEMRGLHAESELKDGISSILVGDLNI
                     APLETDVWSHKQLLKVVSHTPVETENLTGMQQGGAWVDLIRTHIPPEEKVFTWWSYRA
                     KDWAAADRGRRLDHVWSSADLADGLSKIEVLREARGWERPSDHVPVTAHFDF"
     gene            complement(79848..80549)
                     /locus_tag="HPDFL43_18407"
     CDS             complement(79848..80549)
                     /locus_tag="HPDFL43_18407"
                     /note="COG2834 Outer membrane lipoprotein-sorting protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164499.1"
                     /db_xref="GI:163757410"
                     /translation="MEIDMAKQIRADVDRLSATPEMSRRKALGAGLGLGLSLMAGAAG
                     LLAFPGGARGADAAQRVADHFASVKTMTGEFIQFGPNGEQTGGKFFIDRPGKLRFNYE
                     APSSVRVIADGKAVVIGNRKLRTWDLYPLNKTPLKLLLADRIDLSADMVRSVTEDPDL
                     ITIVLGNKTIFGDSTISLMFDPKSFELRQWTIRDAQGKDTSVMIFNVRTGVTFASNVF
                     KVPYDQVHKRQRGGG"
     gene            complement(80646..83219)
                     /locus_tag="HPDFL43_18412"
     CDS             complement(80646..83219)
                     /locus_tag="HPDFL43_18412"
                     /note="COG1674 DNA segregation ATPase FtsK/SpoIIIE and
                     related proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane DNA translocase"
                     /protein_id="ZP_02164500.1"
                     /db_xref="GI:163757411"
                     /translation="MLAGLFQRQLRFAMGMAIIASLALAVAALATWNVSDPSFSNANG
                     ATPVNALGFSGAAFADLVMQFFGLAGVIGLLPALAWALQLMRNRPIDRLSKRAPAWFA
                     GAWLTAAFFGLMPHSQGWPLPNGLGGVLGDMALKIPATFIGGFPSGIIAVILGLLLVP
                     PALWLLGFGAALIGRSPDVETGAGELPDDCDHDEEPMSRGELLVGALAHGWYTLRGRM
                     RRLVGFAGLRNRRAMPDQPFDLNDDYDAPDLYSDPRMAGGRVEPGFSDNSRAVRSRML
                     DDAPPFDVDDGPLPEGLLSGDLDDDPAADWREHAAPAQPARPQQSSPRVSAPAARPKP
                     GERVHRDAQTSMLEDHGFSLPSVHLLNEAKNVVKDATLSPEALEQNARMLEGVLEDFG
                     VKGEIIHVRPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAIAARVAVVPGRNAIG
                     IELPNEKRETVYLRELIGSRDFDNSKAKLGLALGKTIGGEPVIADLAKMPHVLVAGTT
                     GSGKSVAINTMILSILYRMDPSKCRLIMIDPKMLELSVYDGIPHLLTPVVTDPKKAVV
                     ALKWTVREMEERYKKMSKIGVRNIDGFNARVEQAAKSGEPITRTVQTGFDRETGEAVY
                     ETEEFDLTPLPYIIVLIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSV
                     DVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLLGMGDMLYMAGGGRIQRVHGP
                     FVSDKEVEDIVSYLKTQGVPEYLDAITEDDDEDDGGGGGPAGTSNLAESDDPYDQAVA
                     VVLRDGKASTSYIQRRLGIGYNRAASLIERMENEGVISAANHAGKREILVPTEDDIEP
                     R"
     gene            complement(83628..84944)
                     /locus_tag="HPDFL43_18417"
     CDS             complement(83628..84944)
                     /locus_tag="HPDFL43_18417"
                     /note="COG0004 Ammonia permease"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="ZP_02164501.1"
                     /db_xref="GI:163757412"
                     /translation="MSLKSSLLTGLTAAGALAAFAVPAFAQDAAVEYATAAETAFIFN
                     TLLFLIGGFLVMFMAAGFAMLEVGMVRSKNVSMQCLKNVALYSIAGIMFWVIGYSLMY
                     TDVNGYFGTPVPYSWPEAGAANEGDYSVASDWFFQMVFCAATASIVSGTLAERIKLWP
                     FLIFTAILTGILYPISGSWQWGGGWLSEAGFSDFAGSTIVHSVGGWAALAGAIILGAR
                     KGKYGPDGKVNPIPGSSMALATLGTFILWLGWFGFNGASQLAMGSNADVSDISRIFAN
                     TNLAATGGVVAAIILTQVMYKKVDVTMALNGALAGLVSITAEPLMPSPLSAILIGAVG
                     GVIVVFAVPMLDKFKIDDVVGAIPVHLLAGIWGTMAVPLTNDGASFGTQLLGVVAYGV
                     FTFVLAGIVWYILKVTVGIRPTEEEEMVGLDMTEVGVEAYPEFTKA"
     gene            complement(84976..85314)
                     /locus_tag="HPDFL43_18422"
     CDS             complement(84976..85314)
                     /locus_tag="HPDFL43_18422"
                     /note="COG0347 Nitrogen regulatory protein PII"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein PII"
                     /protein_id="ZP_02164502.1"
                     /db_xref="GI:163757413"
                     /translation="MKIVMAIIKPFKLDEVREALTGIGIQGLTVSEVKGYGRQKGHTE
                     IYRGTEYAVSFLPKLKIEIAVASDQVDKAIEAISSAAKTGQIGDGKIFVYSIDQAMRI
                     RTGETDADAL"
     gene            complement(85544..86422)
                     /locus_tag="HPDFL43_18427"
     CDS             complement(85544..86422)
                     /locus_tag="HPDFL43_18427"
                     /note="COG1946 Acyl-CoA thioesterase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioesterase"
                     /protein_id="ZP_02164503.1"
                     /db_xref="GI:163757414"
                     /translation="MSRTAPSAMQQLVSSLDLEVLEQDLFRGTSPQVGWQRVFGGQVI
                     GQALVAAQRTVSADRPVHSLHAYFMRPGDPAAPIIYTVDRIRDGLSFATRRVVAIQHG
                     KAIFSLSASFQKEEEGLEYQASMPEVTPPEKLPGKEEMRAAFLTGAPDHIRSYWERER
                     PIEVRPLALDHYVSDRKLDAEQKVWVRTTGPVPDDRIIQAAILAYLSDMTLLDTALFA
                     HGRSVFDRDLQVASLDHAMWFHRPSRLDDWLLYSMDSPNTNGARGFTRGSLYQRDGRL
                     IASVAQEGLIRDRANA"
     gene            86617..87843
                     /locus_tag="HPDFL43_18432"
     CDS             86617..87843
                     /locus_tag="HPDFL43_18432"
                     /note="COG0654 2-polyprenyl-6-methoxyphenol hydroxylase
                     and related FAD-dependent oxidoreductases"
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="ZP_02164504.1"
                     /db_xref="GI:163757415"
                     /translation="MTKTTMDILVCGGGYVGLSAAVALKLAAPSLDIAVIDAAPEDVW
                     RKDQRASAVAAGARRLLSQLGVWDEIAAEAQPINDMVVTDSRSSDPIRPVFLTFGGAI
                     EAGEPFAHMMPNVAMVGALRRKAEEIGVPIHQSTAASGLEVDEQEARIETADGRTLTA
                     RLVVAADGVRSRLRDMAGIKTQHWDYGQSGIVTTVAHERPHNGRAEEHFMPSGPFAIL
                     PLTGNRSSLVWTERTADAERLINQDDFVFEAELERRFGHHLGELRIEGGRRAFPLGLT
                     LARDFVKPRLALAGDAAHGIHPIAGQGLNLGFRDVAALAETVVEANRLGLDIGSMAVL
                     ERYQTWRRFDTVRMGVTSDLLTRMFSNDITPLRMVRDFGLSLVDRMPAMKRYFIDQAA
                     GIPDASGPRLLRGEAI"
     gene            complement(88012..88584)
                     /locus_tag="HPDFL43_18437"
     CDS             complement(88012..88584)
                     /locus_tag="HPDFL43_18437"
                     /note="COG1309 Transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, TetR family protein"
                     /protein_id="ZP_02164505.1"
                     /db_xref="GI:163757416"
                     /translation="MSKKGDQRRDAIVAAAARMFWANGFAATSIAGIAGEAGVPQGNM
                     FYYYRTKADLALAVADVFVEETQSLITEAEAAAVEPRQRIRFLLNRLGQSNRSRVENG
                     CPISAAVRDFRRAAPEASTRAGQSFELIVSFIARELQKTGPRPSIALARARSMVVEWQ
                     GGIALAHAFDDMTVLVESLRRAEQSLQIGP"
     gene            complement(88722..88895)
                     /locus_tag="HPDFL43_18442"
     CDS             complement(88722..88895)
                     /locus_tag="HPDFL43_18442"
                     /note="COG2835 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164506.1"
                     /db_xref="GI:163757417"
                     /translation="MDVKMLELLVCPLTYGPLKYDSEQNELISERARLAYPVRDGIPI
                     MLVSEARQLPDED"
     gene            complement(88959..89636)
                     /locus_tag="HPDFL43_18447"
     CDS             complement(88959..89636)
                     /locus_tag="HPDFL43_18447"
                     /note="COG2802 Uncharacterized protein, similar to the
                     N-terminal domain of Lon protease"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164507.1"
                     /db_xref="GI:163757418"
                     /translation="MQVGNKSYRTVADVPEQVPVFPLSGALLLPGAQLPLNIFEPRYL
                     AMFDDALVSDRVIGIIQPALENGGNSPGPVKDLCSVGCLGRITSLGETGDGRYVITLG
                     GICRFRVLEELSQDGRPYRVCAIAPFGSDLDAADDGADVDRKALLDSFRAYLDANNLE
                     ADWSSVERASTVSLVNSLSMMSPYGPAEKQALLEAGDTKTRAETLVAITEIALARDGD
                     DYDRVLQ"
     gene            complement(89719..90720)
                     /locus_tag="HPDFL43_18452"
     CDS             complement(89719..90720)
                     /locus_tag="HPDFL43_18452"
                     /note="COG3118 Thioredoxin domain-containing protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative thioredoxin protein"
                     /protein_id="ZP_02164508.1"
                     /db_xref="GI:163757419"
                     /translation="MSDFENPYAPASGAQMSGNVTFGDKPQTAPAVSGQPGQAGGDLI
                     KDTTTADFTADVIQASQDVTVLVDFWAPWCGPCKQLTPVIEKAVQESGGRVKLVKLNI
                     DDHPAIPGQMGIQSIPAVVAFSGGKPVDGFMGALPDSQIREFIEKVAGPPGVSPAEAQ
                     IEAVLEQSRAAMADGNMEQAAQGFAAILQMQSGHAGAAAGLAACMMEMGDLDRAEQML
                     AVIDAEGRKDPEVASVIKRLEMAREVAQLGDPVELEARLAKNPDDHEARLQFAKILNA
                     KGHRDAAAEELFTIMRKDRKWEDEAARKALLEFFEAWGPVDPATLSARRQLSSLLFS"
     gene            complement(90771..91277)
                     /locus_tag="HPDFL43_18457"
     CDS             complement(90771..91277)
                     /locus_tag="HPDFL43_18457"
                     /note="COG3760 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164509.1"
                     /db_xref="GI:163757420"
                     /translation="MTSIPKTRKDLFDRLDALNITHSTMEHPPVFTVAESQGLRDQIP
                     GGHTKNLFLKDKKGRYFLVTLEENAEVNLRTIHTLIGASGRVSFGKHEALMEKLGVAP
                     GSVTIFSAINDPGHDVTIVIDAPLMEYDIINAHPLINEATTSIAREDLKRFLADTGHE
                     PMILKVST"
     gene            complement(91299..91502)
                     /locus_tag="HPDFL43_18462"
     CDS             complement(91299..91502)
                     /locus_tag="HPDFL43_18462"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164510.1"
                     /db_xref="GI:163757421"
                     /translation="MLQSGGPRADLAPDKGRADVRGREPSARPAIAKHGRVAYQGIKR
                     EGAVLPINAKPTIFAFEISKTAL"
     gene            91633..91704
                     /locus_tag="HPDFL43_t21169"
     tRNA            91633..91704
                     /locus_tag="HPDFL43_t21169"
                     /product="tRNA-Gly"
     gene            91915..92349
                     /locus_tag="HPDFL43_18467"
     CDS             91915..92349
                     /locus_tag="HPDFL43_18467"
                     /note="COG1226 Kef-type K+ transport systems, predicted
                     NAD-binding component"
                     /codon_start=1
                     /transl_table=11
                     /product="Ion transport 2"
                     /protein_id="ZP_02164511.1"
                     /db_xref="GI:163757422"
                     /translation="MIVELAIGTVTIITSMTVMIGFVLIALRLVRNAEDNYADHRPAL
                     WQFFLMLAVTVALVLGTNTVCVWLWAGLFRVLGVFATLEEAVYFSMVSFTTVGYGDVV
                     VDKGWRILSGFVAVNGLLAFGIFTAVLIEVIRSLSNRYMPRG"
     gene            92463..92885
                     /locus_tag="HPDFL43_18472"
     CDS             92463..92885
                     /locus_tag="HPDFL43_18472"
                     /note="COG3824 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164512.1"
                     /db_xref="GI:163757423"
                     /translation="MARSDQTGDWQGRHAPSLSVFESIAIDSYARLPDHFRALTGELS
                     IVVEDFPDDEIFEDMGLETPFDLLGLFEGRGLSERFTIETGELPNRIMLYRRPIIDYW
                     AENDETLGDIITHVLIHEIGHHFSMSDDDIERIEAAAE"
     gene            complement(92898..94073)
                     /locus_tag="HPDFL43_18477"
     CDS             complement(92898..94073)
                     /locus_tag="HPDFL43_18477"
                     /note="COG1473 Metal-dependent
                     amidase/aminoacylase/carboxypeptidase"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose synthesis protein"
                     /protein_id="ZP_02164513.1"
                     /db_xref="GI:163757424"
                     /translation="MTLTALLRRTAPAELVTLRHALHRRPELSGQESETAAHIVAELK
                     RHQPDEILTELGSHGVAAIYDSGADGPAVLFRCELDGLPITEISSFGWRSEIEGKGHL
                     CGHDGHMAILCGLAMQLAENRPTRGKVILLFQPAEETGAGAADVIADPRFKRIKPDFA
                     FALHNLPGLPLGAVGVRPGPFTFASEGLAVRLSGRTAHAAQPEAGLSPAAVMGRLMDA
                     LPALPETLGHIPGHSLVTLSHARLGEAAFGIAPGEADIWVTIRAIDDEMQAQLMDEAE
                     KLVHRLADAGGLGVSLDRHEGFAAGHNHEDAVASIEAAALALGAGRVEVGDPYRWSED
                     FGRFGSVAKAALFVLGSGEDHPRLHNPDFDFPDELIGPGVAIFEHIARDLCGEQTAD"
     gene            complement(94070..94276)
                     /locus_tag="HPDFL43_18482"
     CDS             complement(94070..94276)
                     /locus_tag="HPDFL43_18482"
                     /note="COG5515 Uncharacterized conserved small protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164514.1"
                     /db_xref="GI:163757425"
                     /translation="MKLYRLLTGPDDSAFCHKVSLALSKGWELHGSPAYAFNAETGLM
                     QCGQAVTKEVEGKDYSPDMELGEQ"
     gene            complement(94273..95202)
                     /locus_tag="HPDFL43_18487"
     CDS             complement(94273..95202)
                     /locus_tag="HPDFL43_18487"
                     /note="COG2301 Citrate lyase beta subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase, beta subunit protein"
                     /protein_id="ZP_02164515.1"
                     /db_xref="GI:163757426"
                     /translation="MTQTSPSRPARPRRSALYLPAGNSRALAKLPALGCDSVILDLED
                     SVAPGAKHDAREAVRAFFKDGRAAELPEGMEKIIRINTLSSPWGGEDLLAARGCRPDA
                     ILIPKVESPEDIVAVEDALEQTDAPASLRLWAMIETPLGVMNAGRIAQAARTDGARLD
                     CFVVGGNDLIKETGVADLPGRPWLGTWLMQIVLAARAYGLDVLDGVYNDFKDLDGLAA
                     EARDGQAMGFDGKTLIHPGQIGVVNAIFGVDAKRRAEAKAIIDAYAEAGNRDRGVISL
                     DGRMVERLHLEIAERVMEKARRIDLRDQGEGNT"
     gene            95302..95706
                     /gene="leuD"
                     /locus_tag="HPDFL43_18492"
     CDS             95302..95706
                     /gene="leuD"
                     /locus_tag="HPDFL43_18492"
                     /EC_number="4.2.1.33"
                     /codon_start=1
                     /transl_table=11
                     /product="isopropylmalate isomerase small subunit"
                     /protein_id="ZP_02164516.1"
                     /db_xref="GI:163757427"
                     /translation="MEIPPRCLPKPLYCPASITLQGPQEGGLRLQAIEQAISNPHIII
                     MNKGTIVMRKLVAVFAGLGLIIAAFAGLALAFVIGIAAAGAMLVGRLTGRLGPSAPGW
                     RAATQRAAPGGHKSHTRDYRVWNDGRGTIIDM"
     gene            95925..96530
                     /locus_tag="HPDFL43_18497"
     CDS             95925..96530
                     /locus_tag="HPDFL43_18497"
                     /note="COG0066 3-isopropylmalate dehydratase small
                     subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase, small subunit"
                     /protein_id="ZP_02164517.1"
                     /db_xref="GI:163757428"
                     /translation="MQKFDRLTGVAAPLPVVNIDTDMIIPKDYLKTIKRTGLGKGLFA
                     EARYNEDGTENPEFVLNKPAWRNASILVAGDNFGCGSSREHAPWALLDFGIRCVISTS
                     FADIFYNNCFKNGILPIVVSQENLDKLMDDARRGANATVSIDLEAQEIHGPDGGVIGF
                     DVDAFKKHCLLNGLDDIGLTLEKASAIDSYETKAGQNRPWL"
     gene            96599..96853
                     /locus_tag="HPDFL43_18502"
     CDS             96599..96853
                     /locus_tag="HPDFL43_18502"
                     /note="COG0236 Acyl carrier protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164518.1"
                     /db_xref="GI:163757429"
                     /translation="MSDTVETSTIALIATAGEVEPGEISRETELSELEIDSLALTEIV
                     MEIEDEHDIEIDLNTAEAWETLKTVGDLIDMVKKIIAAQH"
     gene            96856..98067
                     /locus_tag="HPDFL43_18507"
     CDS             96856..98067
                     /locus_tag="HPDFL43_18507"
                     /note="COG0304 3-oxoacyl-(acyl-carrier-protein) synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="NodE"
                     /protein_id="ZP_02164519.1"
                     /db_xref="GI:163757430"
                     /translation="MDHRRVVITGIGGICALGGNATDIWTGMKQGRDGCRPLTIEKRD
                     LKTNIGFNIIDYPEDDGIEKRQGMTMSWISRLAVIAAREAFAQSGLSMETTDPKRTGS
                     IVGVGTFGTDALDESYIDIFLEKKKRTQLFTVPKVMPSGPASHVSISLGLKGSVYGVS
                     SACASGNHAFASAVDQIRLGRADVMLAGGAELALVYGPLKAWESLRVLARSACRPFSA
                     DRDGLVLGDGAAIVVLESYEHAKARGADILAEIAGVGLSADASDIVNPSVEGPATAIR
                     NCLADGALSASQIGYINAHGTATQANDKTETQAIRDVLGADADAVSVSSTKSMHGHCL
                     GASSAIELIACINAVREGVVPPTINYTAPDPACDLDVTPNEARERKIDVAISNAFAFG
                     GTNAVVGVKRI"
     gene            98192..99295
                     /locus_tag="HPDFL43_18512"
     CDS             98192..99295
                     /locus_tag="HPDFL43_18512"
                     /note="COG0473 Isocitrate/isopropylmalate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="ZP_02164520.1"
                     /db_xref="GI:163757431"
                     /translation="MTTRSLFLLPGDGIGPEAMAEVRKIIAHMNDADSAGFVTDEGLV
                     GGSAYDAHGQAISDADMDKAMAADAVLFGAVGGPKWDAVPYEVRPEAGLLRLRKDMEL
                     FANLRPAICYPALANSSSLKQDVIEGLDILIVRELTGGVYFGEPKEIIDLGNGQKRGI
                     DTQVYDTYEIDRISAVAFELARTRRNEVCSMEKRNVMKSGVLWNEVVTATHKARFSDV
                     KLSHMLADAGGMQLVRWPKQFDVIVTDNLFGDMLSDIAAMLTGSLGMLPSASLGAPDA
                     KTGKRKALYEPVHGSAPDIAGQGIANPIAMIASFAMCLRYSFNMVAEADRLEAAIAAV
                     LDKGLRTGDIMSDGCQKITTAEMGDAILAAYAG"
     gene            complement(99363..99797)
                     /locus_tag="HPDFL43_18517"
     CDS             complement(99363..99797)
                     /locus_tag="HPDFL43_18517"
                     /note="COG1522 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="AsnC family regulatory protein"
                     /protein_id="ZP_02164521.1"
                     /db_xref="GI:163757432"
                     /translation="MNIDETDRLIVRLLCENARMPVSELARKVGLSGPSTSERIRRLE
                     NNGIIARFTAELDLEALGYPLQAIVRIKPRPGNMHIVEDMILNEPGFLDCDKVTGEDC
                     FVTRLALRSIADLDPVLLPFHDRAETNTAIIKSSPFRSRMPV"
     gene            99928..100782
                     /locus_tag="HPDFL43_18522"
     CDS             99928..100782
                     /locus_tag="HPDFL43_18522"
                     /note="COG0384 Predicted epimerase, PhzC/PhzF homolog"
                     /codon_start=1
                     /transl_table=11
                     /product="phenazine biosynthesis protein, PhzF family"
                     /protein_id="ZP_02164522.1"
                     /db_xref="GI:163757433"
                     /translation="MTVQRIAAFSDAGEGGNPAGIVIADHFPNEADMRRIAAEVGYSE
                     TAFAVPDGDPYRWRVRYFSPESEVPFCGHATIALGAALAGHSGKGRYSLRLNDAEIAV
                     EARATGSGYSATLQSPPTRSSAVRAELVDQALALFGYTAEQLDPALPPAEIHAGADHL
                     VLALKDRADLAAMSYDLDAGRALMRKYGLVTIMLVYVRGQTDFDVRNAFASGGVLEDP
                     ATGAAAAAFSGYLRDLGWPHQNRIRIIQGEDMGAKSVIEAEISDAAGSSIRVSGAARN
                     MAADLVTG"
     gene            100902..101399
                     /locus_tag="HPDFL43_18527"
     CDS             100902..101399
                     /locus_tag="HPDFL43_18527"
                     /note="COG4283 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164523.1"
                     /db_xref="GI:163757434"
                     /translation="MAATTRDELPATNLKEYRKLEALIADLSGEQATIKDDDDTSIKD
                     VIGHRAHWIDLFLGRYEDGQAGKEVSFPAPGYKWNQLKAYNAALREAQAGLSWDEARE
                     PLSANHARLVAFVTRHDDADLYGGPMQGASNDWTPGRWAQAAGPSHCRSAAKHIRQIL
                     KRRAR"
     gene            101606..102637
                     /locus_tag="HPDFL43_18532"
     CDS             101606..102637
                     /locus_tag="HPDFL43_18532"
                     /note="COG0136 Aspartate-semialdehyde dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="ZP_02164524.1"
                     /db_xref="GI:163757435"
                     /translation="MGFKIAIAGATGNVGREMLNILSERGFPVSEVVALASSRSVGTE
                     VSFGDKTLKVKNLETYDFSDTDLCLMSAGGTISKKWSPKIGAQGCIVIDNSSAWRYDA
                     DVPLIVPEVNPDAISGYTKRNIIANPNCSTAQLVVALKPLHDHAKIKRLVVSTYQSVS
                     GAGKDGMDELFNQTRAVFVADPITSQKFTKRIAFNVIPHIDDFMEDGYTKEEWKVLAE
                     TKKMLDPKIKVTCTAVRVPVFIGHSESVNIEFENEITADEARDILRDAPGCQVIDKHE
                     DGGYITPYECAGEDATFISRIREDATVENGLNMWVVSDNLRKGAALNTIQIAELLVNR
                     RLITPRLAA"
     gene            102786..103604
                     /locus_tag="HPDFL43_18537"
     CDS             102786..103604
                     /locus_tag="HPDFL43_18537"
                     /note="COG2951 Membrane-bound lytic murein
                     transglycosylase B"
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane-bound lytic murein
                     transglycosylase signal peptide protein"
                     /protein_id="ZP_02164525.1"
                     /db_xref="GI:163757436"
                     /translation="MTIKSGKLMLWSAATLLAMGLSTPAMSAQCGNNSAGFPAWIEQF
                     KKEAARAGISDRTISRAFANVRYASKTISLDRNQRSFKLSFEQFMQKRGANSIISQGK
                     KLKQRNARLFNALEQKYGVPAGPLIAIWGMESGFGRFSGNQHTMSAVATLAYDCRRSA
                     FFTEQLYAQLQLIQKGWLSPDFKGAAHGEIGQTQFLPANVVRFGVDGDRNGSINLGST
                     ADALASTANFLRGHGWKRGGGYQPGETNFRAIKGWNAAGVYQKAIAKIGAEIDR"
     gene            complement(103630..104052)
                     /locus_tag="HPDFL43_18542"
     CDS             complement(103630..104052)
                     /locus_tag="HPDFL43_18542"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164526.1"
                     /db_xref="GI:163757437"
                     /translation="MGAVRFLIVMLIYSLGAGVAPARADNALLDRWYWALFNVDRGVL
                     SELLSDNALIELEDLGVTQTKMEFIAALDEWEDVAETANFAWQIDAEATQDASQATAL
                     VCYQFPGNDLMVRDFFTFDEGIITGSVQSTVGDTCEDF"
     gene            complement(104120..104770)
                     /locus_tag="HPDFL43_18547"
     CDS             complement(104120..104770)
                     /locus_tag="HPDFL43_18547"
                     /note="COG0288 Carbonic anhydrase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative carbonic anhydrase protein"
                     /protein_id="ZP_02164527.1"
                     /db_xref="GI:163757438"
                     /translation="MSSFPTRLLEGYQSFMSGRYTAERNRYRDLAEAGQEPHTLVIAC
                     CDSRAAPETVFDCGPGELFVVRNVANLVPPYAPDGNFHSTSAALEFAVQSLKIRQIVV
                     LGHGRCGGIKAALDVDAAPLSPGDFIGQWMGLLKPAAQQIKDSVLLTSGERQFALEHI
                     SIRNSIANLRTFPCVKILEDRGKMALHGAWFDISTGELWVMNSQTGDFSRPETSLA"
     gene            complement(104856..105602)
                     /locus_tag="HPDFL43_18552"
     CDS             complement(104856..105602)
                     /locus_tag="HPDFL43_18552"
                     /note="COG4923 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164528.1"
                     /db_xref="GI:163757439"
                     /translation="MITDDAEIPDLAGVDGCRAGWIAWIRTAGSSAPDLRIYSRFADL
                     VEDLGSDAVIAVDMPIGLPERIEGPGRGPEQAIRPFLGARQSSVFSIPARAAVEARSY
                     GEACARALETSDPPKKVSKQAFYLFPRILEIDQVLQADEGLRPRVVECHPEFSFCRLN
                     NGLAMQTPKKIKGKVNPEGIAERVAVLARHRFDPRSFENDPPRGAGMDDVIDAAVNLV
                     MAGRHAAGLTSTFPAHPASDRHGIPIAIHG"
     gene            complement(105599..106492)
                     /locus_tag="HPDFL43_18557"
     CDS             complement(105599..106492)
                     /locus_tag="HPDFL43_18557"
                     /note="COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative pyridoxine kinase"
                     /protein_id="ZP_02164529.1"
                     /db_xref="GI:163757440"
                     /translation="MTTDTRNGTDVRPAVIVISSHVVRGSVGNRAAVFALETLGYPVW
                     ALPTVVLPWHPGHSRATRIVPGKEEFSALIDDLCGSPWLGEVGAVLSGYLGDAGQAQD
                     VARLVGAVREANPEALYMCDPVIGDAGGLYVPEALAGAILKNLIPIANIATPNIFELG
                     WLSGAELTNSTSAVSAAETLGPARVLVTSAPAMMAGSTGNLLISGGAARMAEHRLIPD
                     APNGLGDLMSASFLARLLEGLNEEKALQMATAAVFEILARTARRGADELMLETDAQSL
                     RTPMAMVNMRRMVSAAGRKKP"
     gene            complement(106489..106734)
                     /locus_tag="HPDFL43_18562"
     CDS             complement(106489..106734)
                     /locus_tag="HPDFL43_18562"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164530.1"
                     /db_xref="GI:163757441"
                     /translation="MKDDDEKVREARRTLDRIGQEGGLSATPAMKSAANSVRDHFSAA
                     DADKADPAELWGTRIARALALVALVGLVWFLFGQLSQ"
     gene            complement(106871..107446)
                     /locus_tag="HPDFL43_18567"
     CDS             complement(106871..107446)
                     /locus_tag="HPDFL43_18567"
                     /note="COG2128 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164531.1"
                     /db_xref="GI:163757442"
                     /translation="MTKGPEAVTALKLEQEMPLSEAMQAYFSKCDEKLGMVPNVLKAY
                     AFNTEKLEAFATLYNDLMLAGSGLSKLDRELIAVAVSSVNKCFYCLTAHGAAVRQLSG
                     NPELGEQMVMNYRTADLEPRQRAMLDFAVLMTEDSARIGEEDRQMLRDSGFSDRDIWD
                     IAAVASFFNMTNRMASATDMRPNPEYHGLAR"
     gene            107536..111105
                     /locus_tag="HPDFL43_18572"
     CDS             107536..111105
                     /locus_tag="HPDFL43_18572"
                     /note="COG2902 NAD-specific glutamate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164532.1"
                     /db_xref="GI:163757443"
                     /translation="MGVKNTRKSGSLLAEAESVAKRSKKPHINPEVLFSRVSEDDLEL
                     MVPESLAAATILAEAEIRAWDGNDARMSLVEVDAATSDGRDVSVLAITTRNKPFLYDS
                     VMGEVTSQVRDILMALHPILVVDGKAPATLFSHGDGSEYEHRISHIQIHIPRLGPAAG
                     KELTAQVRHVLDQVQAAVSDWKPMLAMIDHAAADLVALDVDKKTEPARQEALAFIAWL
                     RDNNFTFLGMREYVYSGEGEEAELSRSQTEGLGILADPDVRVLRLGKDQVTTTPEILD
                     FLHGPDFLIVTKANVRSVVHRRTYMDYVGIKRFDLKGRVIGELRIVGMFTSTAYTRSV
                     ANIPLLRSKVQAVTEEFGYDPESHSGKLLLNTLESYPRDDLFQIDVSLLVRFCMQINE
                     LSDRPRVRVLPRIDRFDRFVSLIVYVPRDQYDSIARERIGDYLKTIYNGRVSAYYPAF
                     PEGGVARVHFIIGRSEGRTPQIAQEQLERDVRSIVTRWEDQFQALGGDAAARMSVSQS
                     YKERFRPDEALADLDDILACGEAGTIRIAFYRSQETPDDHLALKIFHAGAPVALSRRV
                     PLLENLGFKVISEQTHEIFLDEQGGQSRAVIVHDMEIIHESNRIVDLDTDRARLEEAF
                     LSVWHGETDNDSYNRLVANTVLSVRQAMVLRAYARYLRQAGIAYSQEYMAQCLNRHPA
                     ISAQLFELFRIRFEIGTSDKDRTKQISDLIEAIESALAEVPSIDDDRILRRYMNAIQA
                     SLRTNFFQTGPDGAPRPALAFKLNPKALDGLPEPRPFREIFVYGAEVEGVHLRFGPIA
                     RGGLRWSDRAQDYRTEVLGLVKAQQVKNAVIVPVGAKGGFYPKQLPADGGRDAIFEAG
                     RNAYKLFIRTLLSVTDNIVGDDVVPPANTVRHDGDDPYFVVAADKGTATFSDTANALS
                     QEQDFWLDDAFASGGSAGYDHKKMGITARGAWEAVKRHFREMDIDIQTTPFTAAGVGD
                     MSGDVFGNGMLLSEKIRLVAAFDHRDIFIDPDPDCETGFAERKRLFELGRSSWQDYDT
                     SKLSKGGMIIPRTLKSVDLTPEAAAAIGLSGRKSTPQEIMIAVLSMEIDLLWFGGIGT
                     YIKDARENDADVGDRANDPIRIVARQVRAKVIGEGANLGVTQKGRIAYALAGGRCNSD
                     AIDNSAGVNSRRRGQHQDRTGKRHARGPFDPAQAEQTACLDDR"
     gene            111044..112324
                     /locus_tag="HPDFL43_18577"
     CDS             111044..112324
                     /locus_tag="HPDFL43_18577"
                     /note="COG2902 NAD-specific glutamate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164533.1"
                     /db_xref="GI:163757444"
                     /translation="MREDRLTRPKRNKLLASMTDEVAELVLRNNYLQTLAISLAEAQG
                     ASGVGELNRVMTNLEGRELLDRKVEDLPDDTLVAERLASGQALSRPEIGVLLSYAKLV
                     LFDEIVASSLPDDPYFSDTLKSYFPKKMLKSHETDIISHRLRREIISTLIGNDAINRG
                     GPAFVIGLGDKSGATAAEIVKAFVLARDGLSLDRLYGEIDGLDTRIPGPVQNRLYAHV
                     GDTVRTVSSWALKTGAAQGDLSKAVASMRDGAAKLGSRIQSAMPDFMREEAERIKAEL
                     IEHGVPEKLAGEIAALGGMSLTPDICHVADASGTDLKRAMDAFFSVTEAFRIGRIVAA
                     VDRIPVSDHFEGLALARSLDEISQARRIISSTALDSNPDDSDPAGAWLSGNKDRIGHV
                     AGQILSLTDSGELTLAKLTVAAGMMSDLARSLRP"
     gene            112353..113768
                     /locus_tag="HPDFL43_18582"
     CDS             112353..113768
                     /locus_tag="HPDFL43_18582"
                     /note="COG2270 Permeases of the major facilitator
                     superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164534.1"
                     /db_xref="GI:163757445"
                     /translation="MNDLMQNGAADSGAGAKKRGVFGWMMFDWAAQPFFTVVTTFIFG
                     PYFISRMASDAATGQAAWGYGIAAGGFLIAILSPILGSIADQTGPRKPWIAFFAAIKI
                     AALCGLWFAAPGSNLVLVVTVFTLAAVAAEFSIVFNDSMLLRIVPKADIGRVSNLAWG
                     LGYLGGMIVLIFIIAFLAASPETGRTLIGLEPLFGLDPLQGEDARASGPISALWYAVF
                     ILPMFLFTPDAGERRAMGGAVRDGLKELKSTLREVRQRAGIFRFLIARMIYQDGVNAL
                     LALGGGFAAAMFGWSITEIGVYGIMLNVVAIFSCLYASRLDTQLGSKLVVMIAIIMLL
                     VATIGIVSTGPGYTFFGALGFAGTDTGGLFGTQAEKAYIAFGLLIGIAFGPVQASSRA
                     YMARSVSKDEAGRYFGIYALAGRATSFLAPFMVASVTAASGSPRLGIATIAIFFAVGL
                     YVLWTTPYPADKPDGKPANVL"
     gene            complement(113817..115433)
                     /gene="purH"
                     /locus_tag="HPDFL43_18587"
     CDS             complement(113817..115433)
                     /gene="purH"
                     /locus_tag="HPDFL43_18587"
                     /EC_number="3.5.4.10"
                     /note="COG0138 AICAR transformylase/IMP cyclohydrolase
                     PurH (only IMP cyclohydrolase domain in Aful)"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="ZP_02164535.1"
                     /db_xref="GI:163757446"
                     /translation="MAVVSKHHPAPDMVRIRRALLSVSDKSGLVEFARGLVDAGVELV
                     STGGTRLALEKEGLAVRDVSELTDFPEIMDGRVKTLHPGVHGGLLAIRDDAEHQQAMQ
                     SHGIAEIDLAAINLYPFEETVARGADAATTVENIDIGGPAMIRASAKNHAYVTAVTDP
                     DDYGRVLEALKTNDGCIPLALRKELAALAFARTAAYDAAVSGWFAGELDLESPRHRAF
                     GGRLHAVMRYGENPHQQAAFYTNGNNRPGVAGAQLLQGKQLSYNNINDTDAAFELVSE
                     FDPAAGAACAIIKHANPCGVAVGESLVEAYGRALACDQTSAFGGILAFNQVLDGETAS
                     EIVKIFTEVIIAPDASEEAREILSAKKNLRLMITGGLADPRQPGIMVKSVSGGLLVQS
                     RDNGSRTADDFKIVTKRAPDARELDDMAFAFRVAKHVKSNAIVYALNGATVGIGAGQM
                     SRVDSARIAARKAVDAAEVLGLDTPLTKGSVVASDAFFPFADGLLSAIEAGATAVIQP
                     GGSMRDQDVIDAADEAGVAMVFTGMRHFRH"
     gene            complement(115541..117250)
                     /locus_tag="HPDFL43_18592"
     CDS             complement(115541..117250)
                     /locus_tag="HPDFL43_18592"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164536.1"
                     /db_xref="GI:163757447"
                     /translation="MAISILDSQRSASLYVAEIWRRLTRRAALGRISAMRFAGSTPDR
                     LVVAPIDLRIADAHIASEIYAGRFALAGRMIDTNGQSPFHMDMPDEAFLRSLHGFGWL
                     RHMRAADHELAFANARALVDDWITVEGRRFGGLPHEPDVVAARLIAWFSHSPIVLRGA
                     DHGFYRRFLKSIAQQTRYLRLVSASLPTGVTRFKARIALAMASLCLPASNGTIRAAAR
                     NLDHEFQSQVLPDGCHVSRNPMVLIELLMDLLPLRQTYVNVGQSPPHNMAAGMDRLFG
                     GLRFFRHSDGELALFNGASAVSADRLLAVLRYDETSGAPFREMPHGNYQRLAIGNVVL
                     IADTGVPPRSVASQAAHAGCLSFELSSGSNRYIVNAGAPVYAESDYVGFARMTAAHST
                     VTLNDSSSLRFSQSDFLGPIVTGGLHKVSVESLDESGKQVGFSATHNGYAGNLKLLHR
                     RKVRLLASGHEVQGRDQILGLDEASPKPENQTVAVARFHVHPSIRISQSEDGAVHLTA
                     GDGETWAFVARDLRPVIEEDVHFADLAGARASKQITLTIKVGETSQIDWKLVRIALPR
                     AAS"
     gene            complement(117392..118732)
                     /locus_tag="HPDFL43_18597"
     CDS             complement(117392..118732)
                     /locus_tag="HPDFL43_18597"
                     /note="COG0144 tRNA and rRNA cytosine-C5-methylases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ribosomal RNA small subunit
                     methyltransferase B"
                     /protein_id="ZP_02164537.1"
                     /db_xref="GI:163757448"
                     /translation="MPSRYDPVDLKPGLAARQAATRLLAAVTESRASLDGLLDPAGGN
                     PAFTGLGPQDRLLVRAILLSALRHLRVIDAYIDELVTSPLPEGAKALRQLLRVGAAQI
                     LFLDVPDRAAVDLAVSQANGDPRNRRFAGLVNALLRRMGREKESRLSELTATVPPFPD
                     WFVSRIQNAYSQEADSILSMLSVPPAIDLTVKTDPAGWAERLGGTVLPTGSVRIARPA
                     GPVTDLEGYDGGDWWVQDAAASIPAQMFSRLDGLEVADLCAAPGGKTAQLALAGARVT
                     ACDQSANRLERLKGNLSRLGLEVSTHLSRAQDFKAPEGFDGVLVDAPCSSTGTVRRHP
                     DIPYTKGPEDITRLTQVQRALLDHAAGLVRPKGELVFSNCSLDPEEGELMVQGFLADH
                     PSWRIKPVDASRWPGMEAAITELGEVRTHPAMLSDDDPAQAGLDGFYAVVLTQE"
     gene            complement(118774..119730)
                     /locus_tag="HPDFL43_18602"
     CDS             complement(118774..119730)
                     /locus_tag="HPDFL43_18602"
                     /EC_number="3.4.24.-"
                     /note="COG0501 Zn-dependent protease with chaperone
                     function"
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HtpX"
                     /protein_id="ZP_02164538.1"
                     /db_xref="GI:163757449"
                     /translation="MNLIRTAMLLALMTALFMGVGFLIGGTGGMMIALVIAAGMNLFS
                     YWNSDKMVLRMHNALEVDAKTAPEFYQMVSDLAQNAGLPMPRVYVIKNAQPNAFATGR
                     NPDNAAVAASTGLLESLTEEEIAAVMAHELAHVQHRDTLTMTITATLAGAISMLGNFA
                     LFFGGNRNSNPLGFIGVLVAMIVAPFAAMLVQMTISRTREYAADRRGAEICGNPLWLA
                     SALRKISAGAGRIVNEDAERNPATAHMFIINPLNGQRMDSLFSTHPATENRIAALESM
                     AGEMAAPSAHRPSDRPARPTSTSVPRTGPWGRDGSTRKGPWS"
     gene            119885..120124
                     /locus_tag="HPDFL43_18607"
     CDS             119885..120124
                     /locus_tag="HPDFL43_18607"
                     /note="COG5508 Uncharacterized conserved small protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164539.1"
                     /db_xref="GI:163757450"
                     /translation="MPMTQDDQQPKQSETDAVETDTPKRELSPAAKRALAEADERRKA
                     RDTAKISTEKEIGGRGGADPARFGDWEIDGRAIDF"
     gene            120199..120663
                     /locus_tag="HPDFL43_18612"
     CDS             120199..120663
                     /locus_tag="HPDFL43_18612"
                     /note="COG1525 Micrococcal nuclease (thermonuclease)
                     homologs"
                     /codon_start=1
                     /transl_table=11
                     /product="nuclease (SNase-like) protein"
                     /protein_id="ZP_02164540.1"
                     /db_xref="GI:163757451"
                     /translation="MVTTLVFVTILATELFTNAPAFAAESAWRTVAGPVLARIVRVID
                     GDTLLVDAHPWPGHAVRVSVRLRGIDTPERRSKCSRERLAADSARSELERLVAGYSTV
                     ELSNVSGGKYYGRVLADLKAGKRDVAAAMLESGLATPYEGGKRTKSKAPCNS"
     gene            complement(121101..123053)
                     /locus_tag="HPDFL43_18617"
     CDS             complement(121101..123053)
                     /locus_tag="HPDFL43_18617"
                     /note="COG0365 Acyl-coenzyme A synthetases/AMP-(fatty)
                     acid ligases"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-coenzyme A synthetase"
                     /protein_id="ZP_02164541.1"
                     /db_xref="GI:163757452"
                     /translation="MSQKSYKVLKDAKTRALIDDETYEKWYKQSVKDPEKFWAKHGKR
                     IDWFKPYTKVKNTNFNGKVSIKWFEDGVTNVSYNCIDRHLKKRGDQVAIIWEGDNPYD
                     DKKITYRELYDQVCRLANVMKSNGVKKGDRVTIYMPMIPEAAYAMLACTRIGAIHSIV
                     FGGFSPDALAGRISDCESTFVITADEGLRGGKKIPLKHNTDLAIEIAARDGVVVKNVL
                     VVQRTAGKVEWFENRDIWYHEAVAAAKPDCPPAKMKAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYASMTHEYVFDYHEGDIYWCTADVGWVTGHSYIVYGPLANGATTLMFEGVP
                     NYPSPSRFWDVVDKHQVNIFYTAPTAIRALMGAGDAHVKKSSRKSLRTLGSVGEPINP
                     EAWEWYYNVVGEKKCPIVDTWWQTETGGILITPLPGATKLKPGSATRPFFGVQPQLVD
                     NDGDVLEGTTEGNLCITDSWPGQMRTVYGDHERFIQTYFSTYKGKYFTGDGCRRDEDG
                     YYWITGRVDDVINVSGHRMGTAEVESALVSHDSVSEAAVVGYPHDVKGQGIYCYITLM
                     EGQEGSDELRKALVGHVRHEIGPIASPDKIQFSPGLPKTRSGKIMRRILRKIAEDDFG
                     ALGDTSTLADPGVVDDLIENRQNKKG"
     gene            123295..123993
                     /locus_tag="HPDFL43_18622"
     CDS             123295..123993
                     /locus_tag="HPDFL43_18622"
                     /note="COG3820 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164542.1"
                     /db_xref="GI:163757453"
                     /translation="MAQQLLMPKATAVWLVDNTALSFDQIAQFCKLHPLEVKAIADGE
                     SSQGIKGLDPVATGQLSREEISAAEGNPEHKLKLSEPKVRVPETKRKGPRYTPVSKRQ
                     DRPNAILWLVRNHPELKDAQISRLVGTTKSTIEQIRGRTHWNAANLTPMDPVTLGLCT
                     QIDLDLEVERAAKNRGPVTEDQQGSVLVSARETETAEPMEETGDKEIDADAVFAKLTS
                     MKRTETEDDDSNTN"
     gene            complement(124063..124854)
                     /locus_tag="HPDFL43_18627"
     CDS             complement(124063..124854)
                     /locus_tag="HPDFL43_18627"
                     /note="COG1028 Dehydrogenases with different specificities
                     (related to short-chain alcohol dehydrogenases)"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="ZP_02164543.1"
                     /db_xref="GI:163757454"
                     /translation="MIMRLDGRTAIVTGGAKGIGLAIVRRLASEGARVMIADIDEAAG
                     TAAVEAASGGGEVRFTATDVSERLDVHNLVAKTIDTFGSIDALVNNAGIVHAADFLDL
                     EEADFDRVLNVNLKSAFLCGQAVARHMVEQIAAGGEPGSIVNMSSINDTFAIANQVPY
                     SVSKGGVSQLTKVMALSLAPHGIRVNAVGPGSIMTDLLASVAENPEARSRILSRTPLG
                     RIGEPAEIAAVTAFLLSRDASYVTGQTIYADGGRMPLNYTVPVKE"
     gene            complement(124851..125003)
                     /locus_tag="HPDFL43_18632"
     CDS             complement(124851..125003)
                     /locus_tag="HPDFL43_18632"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164544.1"
                     /db_xref="GI:163757455"
                     /translation="MKLDRQIPFHLIKTRWTFALFDSTHRSDQMRTLACWFASTIQPG
                     RIIWKE"
     gene            complement(125043..126953)
                     /locus_tag="HPDFL43_18637"
     CDS             complement(125043..126953)
                     /locus_tag="HPDFL43_18637"
                     /note="COG0365 Acyl-coenzyme A synthetases/AMP-(fatty)
                     acid ligases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-coa synthetase protein"
                     /protein_id="ZP_02164545.1"
                     /db_xref="GI:163757456"
                     /translation="MTSSYDEVYGSWRKDPEGFWMDQASGIDWFEKPKIAFDPDQGVY
                     GRWFPDGVTNTCHNCLDRHVEGGRGDQAAIIYDSPITGAKRTISYSEMLADVEAFSGA
                     LSDRGIRKGDRVIIYMPMVPEALVAMLACARLGAVHSVVFGGFAASELATRIEDCEAK
                     LVVSASCGIEPGRIVAYKPLLDAAIEQSSHKPDVTIILQREEHRCELIKDRDFDFHAL
                     LQANAGRKVTCTPVASTDPLYVLYTSGTTGQPKGVVRDNGGHMAALHWSMHSIYGVKP
                     GEVFWAASDIGWVVGHSYIVYGPLLHGNTTILFEGKPVGTPDAGTFWRVIDEHNVVVL
                     FTAPTAFRAIRKEDPQGSLISDYDLSGFCALFLAGERADPDTIQWAERLLKVPVIDHW
                     WQTETGWTIAGNPMGLGLLPIKHGSPAVPMPGYDVQVIDDAGHPVAAGTLGNIVVKLP
                     LPPGCLPTLWNADDRFQDAYLAEFPGYYKTADAGFIDDNGYLFIMARTDDIINVAGHR
                     LSTGGMEEAVSGHPDVAECAVIGIADSMKGQIPAGFIVINSGVDRSDDEIEKEVVKLV
                     RDKIGPVAAFKTVMAVKRLPKTRSGKILRATMQKIADGESWKMPATIDDPAILDEVSE
                     VLAKRGLKSRDS"
     gene            complement(127215..127895)
                     /locus_tag="HPDFL43_18642"
     CDS             complement(127215..127895)
                     /locus_tag="HPDFL43_18642"
                     /note="COG0325 Predicted enzyme with a TIM-barrel fold"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164546.1"
                     /db_xref="GI:163757457"
                     /translation="MERQMDATKNLAKVLADIADAETSAGRPAGSVGLVAVSKTKPVE
                     EIRPVIAAGRRVFGENRVQEAQSKWPQLKAETPDLELHLIGPLQSNKTADAVALFDVI
                     QTVDREKIAREIAREIKKQGRAPGLFIQVNTGSEPQKAGIEPDAAAAFVDLCRSELGL
                     TIRGLMCIPPFDENPGPHFALLANIAREAGLEELSMGMSDDYPIAIAFGATQVRVGSA
                     IFGARNTH"
     gene            128161..130791
                     /gene="leuS"
                     /locus_tag="HPDFL43_18647"
     CDS             128161..130791
                     /gene="leuS"
                     /locus_tag="HPDFL43_18647"
                     /EC_number="6.1.1.4"
                     /note="COG0495 Leucyl-tRNA synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl-tRNA synthetase"
                     /protein_id="ZP_02164547.1"
                     /db_xref="GI:163757458"
                     /translation="MAIERYNPKQAEIRWQRQWDEAKIYETDNDSPDPKYYVLEMFPY
                     PSGRIHMGHVRNYALGDVVARYKRARGFNVLHPMGWDAFGMPAENAAMQNKVHPREWT
                     YANIDAMRKQLKSMGLSLDWSREFATCDVDYYKQQQALFLDFLAAGLIYRRNSKVNWD
                     PVDMTVLANEQVIDGRGWRSGALVEQRELTQWFFRISDFAEDLLQSLDGLDQWPEKVR
                     LMQKNWIGKSEGLSLRWQIADPETAGGASEIEVYTTRPDTLYGASFMAIAADHPIAKD
                     LATKDPAIAEFCDQCRRAGTSLAALETAEKIGYRTPVNVVHPLDPDWTVPVYIANFVL
                     MDYGTGAIFGCPSGDQRDLDFARKYNLPVTPVVMPADADAASFVITDEAYVGDGVMIN
                     SRDLDGLSPAEAFDRVASMLEARTLDDAPQAARKTNFRLRDWGLSRQRYWGAPIPVIH
                     CDICGVVPVPAKDLPVQLPDDVTLDTPGNPLDHHPTWRHIACPTCGQDARRETDTMDT
                     FVDSSWYFARFTAPRCDTPTEPAAANAWLPVDQYIGGIEHAILHLLYSRFFTRAMQKT
                     GHVDLKEPFRGLFTQGMVVHETYRAERDGKKEWIAPADVIIEEQNGKRQARHSQTGES
                     LSIGSIEKMSKSKKNVVDPDDIIDGYGADTARFFMLSDSPPDRDVIWSEAGVEGAHRF
                     VQKIWRLIGEASENLKSAEAAAGAESRALEVSRASHKTVKAVGEDIEKLAFNKAVARL
                     YELVNTLAGPLSDVAAGKADEVLTSACKQAASHLVQLFAPMMPHLAEECWILLGNDGM
                     VATSTWPAYDPALVIDDQITLPVQINGKKRGDLTIDADADQAAVEQAVLALDFVQAST
                     GGNPPRKLIIVPRRIVNVVI"
     gene            130796..131293
                     /locus_tag="HPDFL43_18652"
     CDS             130796..131293
                     /locus_tag="HPDFL43_18652"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164548.1"
                     /db_xref="GI:163757459"
                     /translation="MRPARSTRLSIRFAALTLGAALLAGCQAQPLYGNLSGQERSITV
                     SRVDSRIEQVVRNELVLGFGGEQSAGAYTLDLTASASISGILPGGVDNEFSAARATVT
                     ASYVLKATGTGETIKSGVRSAEAQLDLPSQSVAQQRAMLEAETRAARAVAALVRADVA
                     SVLPR"
     gene            131318..132346
                     /locus_tag="HPDFL43_18657"
     CDS             131318..132346
                     /locus_tag="HPDFL43_18657"
                     /note="COG1466 DNA polymerase III, delta subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164549.1"
                     /db_xref="GI:163757460"
                     /translation="MAQIKNHEFAGFVRRQGTPFRIVLVYGPDRGLVSERAAQVAAKT
                     GVDLSDDFSVLKLEASDLSGDPGRLADEFGAISLFGGDRLVWIKNAGNERGLVDAVAA
                     VSQSDPGTSHLLIEAGDLKKGAGLRKTIEAAKTALAIPCYADDARGVQALIDEELGGA
                     GLTIQGEARQRLSQLLGGDRLASRGELKKLALYCHGSGTVTDADVVEAIGDVAALSVD
                     DAIEAVFSGDPGRLEAALERILASKTSVFLVLRGCMVQLEQLDGMRSLVEGHSRQPAQ
                     VMADKGRGIHFKRKPIVERALRHWTLKAINAEMYRLAQAVLETRKRPQLEASIARQAL
                     LRTCLLSR"
     gene            complement(132367..133263)
                     /locus_tag="HPDFL43_18662"
     CDS             complement(132367..133263)
                     /locus_tag="HPDFL43_18662"
                     /note="COG1475 Predicted transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="putative chromosome partitioning protein"
                     /protein_id="ZP_02164550.1"
                     /db_xref="GI:163757461"
                     /translation="MAEDVSKKRLGRGLAALIGEIDQPVSPQAKPSVSADRMVPIEHV
                     TRNPRNPRRNFAPSDLEDLSRSIRQHGVVQPVVVRTAAEGRYEIIAGERRWRASQMAG
                     LVEIPVIVRDVDDKTALEIAIVENVQRADLNPLEEAQGYEQLIAQYGYTQNDLGEVIG
                     KSRSHVANSLRLLKLPEDVRTMLSDGVLSAGHARAIVSTSNPAALAKLIVDGGLSVRD
                     AERMAQKDSEEAAQTGGLETKSARQPDNKDADTVALEKSLTDVLGLKVQLAHKGQGGQ
                     LRIDYKTLEQLDELCRLLGDNR"
     gene            complement(133299..134093)
                     /locus_tag="HPDFL43_18667"
     CDS             complement(133299..134093)
                     /locus_tag="HPDFL43_18667"
                     /note="COG1192 ATPases involved in chromosome
                     partitioning"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein A"
                     /protein_id="ZP_02164551.1"
                     /db_xref="GI:163757462"
                     /translation="MPHAKNRIITIANQKGGVGKTTTAINLATALAAIGEEVLIVDID
                     PQGNASTGLGIDRRDRGVSAYDLLTQNASVSDTAIETAVPHLSIIPSTMDLLGVEMEI
                     AGTPDRVFRLRKALQADDAKSYSYVLIDCPPSLNLLTMNAMAAAHSILVPLQCEFFAL
                     EGLSQLLETVGQVRDTLNPTLDIQGIVMTMFDARNNLALQVVDDVRAHLGEKVYRTLI
                     PRNVRVSEAPSYGKPAILYDLKCAGSQAYLQLASEVIQRERNRKAA"
     gene            complement(134112..134738)
                     /gene="gidB"
                     /locus_tag="HPDFL43_18672"
     CDS             complement(134112..134738)
                     /gene="gidB"
                     /locus_tag="HPDFL43_18672"
                     /EC_number="2.1.-.-"
                     /note="COG0357 Predicted S-adenosylmethionine-dependent
                     methyltransferase involved in bacterial cell division"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-inhibited division protein B"
                     /protein_id="ZP_02164552.1"
                     /db_xref="GI:163757463"
                     /translation="MRQYPLDSGFVSRETRERLETYADLVRKWQSRINLISPKTLPDL
                     WNRHIIDSLQLFALKPQPVQWMDIGSGAGFPGLVTAICLTEIGEGWVHLVESNNKKAA
                     FLRQVIGQTGARASVLPIRIDAARAKVGSMDAISARALASLPDLLSHCAPFVEDNPKT
                     EMWFHKGLDYFDEVRSARDLWAFDLVEHRSQLQDGSVILQISNLSKPT"
     gene            complement(134761..136629)
                     /locus_tag="HPDFL43_18677"
     CDS             complement(134761..136629)
                     /locus_tag="HPDFL43_18677"
                     /note="COG0445 NAD/FAD-utilizing enzyme apparently
                     involved in cell division"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-carboxymethylaminomethyl
                     modification enzyme GidA"
                     /protein_id="ZP_02164553.1"
                     /db_xref="GI:163757464"
                     /translation="MDYDVIVIGGGHAGSEAAAASARMGVRTVLVTHKRKSIGVMSCN
                     PAIGGLGKGHLVREVDAMGGLMGLAADQSGIQFRMLNRRKGPAVWGPRTQADRKLYKA
                     SIQAQLSAIDNLDVIEAEADGLVQDGQGPTHVVLKDGRQIGCKAVVLTTGTFLRGLIH
                     IGDQRIPAGRMNEAPALGFSNVLENAGFELGRLKTGTPARLDGKTIDWDQVGWQEADA
                     EPIPFSFMTDHIEVPQIRCGITRTTAATHKIIQDNIHRSAMYSGQIEGVGPRYCPSIE
                     DKIVRFGERDGHQIFLEPEGLDDDTVYPNGVSTSLPEEVQEAFLRSIPGLQDVRIIQP
                     GYAIEYDHVDPRELSHTLETRRIPGLFLAGQINGTTGYEEAAAQGLVAGLNAALLVQG
                     RESCLFSRTNSYIGVMIDDLTTKGVSEPYRMFTSRAEYRLSLRADNAEQRLTPLAIEL
                     GCLSSERVEKSATYFDSLSKCLADLNARNLTPNQAASRGISLNQDGLRRSAFQLLSYP
                     EVSLEQILSVWPDLEVYGDKVLAAAAVDAAYAVYLDRQQQDIAQRQKEEARAIPADFD
                     YGVLNGLSNELKQKLERFRPPSIGHAERIEGMTPAAIALLLAHLRRTDTVGSARAS"
     gene            complement(136619..136822)
                     /locus_tag="HPDFL43_18682"
     CDS             complement(136619..136822)
                     /locus_tag="HPDFL43_18682"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164554.1"
                     /db_xref="GI:163757465"
                     /translation="MTSTMIHVKHRKPEMSCAAVVFITTILTPFARWEWINAQRLFHV
                     KRLSLDLSALMANNTALETCYGL"
     gene            complement(136847..138034)
                     /locus_tag="HPDFL43_18687"
     CDS             complement(136847..138034)
                     /locus_tag="HPDFL43_18687"
                     /note="COG0486 Predicted GTPase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative tRNA modification GTPase"
                     /protein_id="ZP_02164555.1"
                     /db_xref="GI:163757466"
                     /translation="MATFCDIKDKNQLRLDRGLVLFFPAPHSFTGEDVAELHIHGSRA
                     SVAAVLMALTDLDGFRLAEPGEFTRQAFENGKLDLTEVEGLSDLIRAETESQRRQALL
                     QADGVLRSLYEGWARRLTHARAMIEAELDFSDEDDIPGSVSDQIWKDMGLLLAEIRSH
                     LECASAAEVVRDGYRIALIGPPNAGKSSLLNYLSKRDVAIVSDIPGTTRDVVEVRLDI
                     AGYLVVLQDTAGLRESSDQIEIEGIRRSLIAAEDADLVLELHEFGVPGRVVPSGVNER
                     IEIVTKVDCLDEPFTADDAAFGISTLTGAGIDKLLEAISERLENLAPSGEMGLPTRAR
                     HVDLLQDCVTAIEVAMKSAEAPIEVRSEYLRHAANSMGRITGMVDVEDLLGVVFSEFC
                     VGK"
     gene            complement(138203..139468)
                     /locus_tag="HPDFL43_18692"
     CDS             complement(138203..139468)
                     /locus_tag="HPDFL43_18692"
                     /note="COG1158 Transcription termination factor"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="ZP_02164556.1"
                     /db_xref="GI:163757467"
                     /translation="MQEMKLQELKNKTPTDLLAFAESVEVENASVMRKQELMFAILKQ
                     LAAQDVEIIGEGVVEVLQDGFGFMRSANANYLPGPDDIYISPSQIRRFSLKTGDTVEG
                     PIRGPKEGERYFALLKVNTINFEDPEKIRHKVHFDNLTPLYPNERFKMEIDNPTSKDI
                     SSRVIDLVAPLGKGQRGLIVAPPRTGKTVLLQNIAHSITANHPDCYLIVLLIDERPEE
                     VTDMQRSVKGEVVSSTFDEPAVRHVQVAEMVIEKAKRLVEHGRDVIILLDSITRLGRA
                     YNTVVPSSGKVLTGGVDANALQRPKRFFGAARNIEEGGSLTIIATALIDTGSRMDEVI
                     FEEFKGTGNSEIVLDRKVADKRIFPSMDILKSGTRKEDLLVPRQDLQKIFVLRRILAP
                     MGTTDAIEFLIDKLKQTKTNGDFFDSMNT"
     gene            complement(139650..140195)
                     /locus_tag="HPDFL43_18697"
     CDS             complement(139650..140195)
                     /locus_tag="HPDFL43_18697"
                     /note="COG1981 Predicted membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164557.1"
                     /db_xref="GI:163757468"
                     /translation="MSTDVATSAGEGKRARGKAYLSIAGVVGLAALGLWYDPPWLYDW
                     LKVLHIVAVISWMVGLFYLPRLFVYHADAETGSEPSETFVVMERRLIKVIMNPAMMVS
                     WVVGLWLAWSGFAFLGVWLWVKIAAVIGLTVFHVFLSRAARRFASGSNHMSARQWRMA
                     NEIPTVLMILVIIMVIIKPFS"
     gene            complement(140192..141235)
                     /gene="hemE"
                     /locus_tag="HPDFL43_18702"
     CDS             complement(140192..141235)
                     /gene="hemE"
                     /locus_tag="HPDFL43_18702"
                     /EC_number="4.1.1.37"
                     /note="COG0407 Uroporphyrinogen-III decarboxylase"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="ZP_02164558.1"
                     /db_xref="GI:163757469"
                     /translation="MMTNVGDRKVMKVLAGETVFPPPVWLMRQAGRYLPEYRKTRATA
                     KGFLNLCYTPDLAVEVTLQPIRRYGFDAAILFSDILVIPDALDRNVHFVEGEGPKMDP
                     IAPEAIARLDASGMHDHLAPVYETVRRLRAELPQETTLLGFCGAPWTVATYMIAGHGT
                     PDQAPARLFAMQHAEEFKMLIDRLTEISTDYLIAQIDAGADAVQIFDSWAGVLSEVDF
                     QSYSVQPVKRMVERINRERPGVPVIGFAKGAGALLENYREETGVNCVGLDWTVPASLA
                     RRIQKGGAVQGNLDPLRVIAGGSALDEGVDLVLETLGEGPLIFNLGHGITPQADPENV
                     TRLMNRIRGAAKS"
     gene            141411..142430
                     /locus_tag="HPDFL43_18707"
     CDS             141411..142430
                     /locus_tag="HPDFL43_18707"
                     /note="COG1806 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164559.1"
                     /db_xref="GI:163757470"
                     /translation="MLKDHSDLKPAKIRFGKLIPKSPKPSPDSFPETTIVEKPSPCPL
                     LSQPLTPYLVPVPSYQQTAEISVEQVKNYFHLHLISDSTGETLMAAGRAAAAQFQGAQ
                     ALEHVYPLIRTRKQLFAVLDAIDGAPGIVLYTIVDSELAAIIELKCRDMGLPSVSVLE
                     PVINVFQSYLGAPSRRRVGAQHAMGEDYFKRIDALNFTLDHDDGQLPADFDEADLVII
                     GISRTSKTPTSIYLANRGIKTANIPIVHGVPLPEGLITAKKPLVVGLIASVDRIAQVR
                     QNRVLGSTAGYQGEHYTDRSLISEELKYARSLCERHNWPAIDVTRRSIEETAAAILAL
                     RPKWR"
     gene            142454..143059
                     /gene="maf"
                     /locus_tag="HPDFL43_18712"
     CDS             142454..143059
                     /gene="maf"
                     /locus_tag="HPDFL43_18712"
                     /note="COG0424 Nucleotide-binding protein implicated in
                     inhibition of septum formation"
                     /codon_start=1
                     /transl_table=11
                     /product="Maf-like protein"
                     /protein_id="ZP_02164560.1"
                     /db_xref="GI:163757471"
                     /translation="MGAFMSTKLVLASASPFRKALLQNAGLSFVAEAADIDERAIEDT
                     LGAMDPEDVAIILAEAKAQDVSARHPGCVVIGSDQTLALEGEVFHKPKDMEDARRRLL
                     KLSGRTHQLNSAVVLARDGETLWRHVSVARMTMRQLDPGFIGRHLASAGDRILSSVGA
                     YQYEGEGIQLFERIEGAYFTIIGLPMLPLLAELRSLEVIDG"
     gene            143052..143906
                     /locus_tag="HPDFL43_18717"
     CDS             143052..143906
                     /locus_tag="HPDFL43_18717"
                     /note="COG0169 Shikimate 5-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate 5-dehydrogenase protein"
                     /protein_id="ZP_02164561.1"
                     /db_xref="GI:163757472"
                     /translation="MADQNPLHPRAFVIGDPISHSRSPLIHRHWLETAGIKGSYDPVH
                     IRESDLKRFVAALKDGTSSYAGGNVTLPHKQAIADLVDNIDETAKQIGAVNTVWLEAG
                     RLCATNTDSHGFSANLDELEPGWDRGKTAVVFGAGGASRAILHALKARGFTSIRIVNR
                     TLARAQELSDRFGGGVSAHSIDELDDVSSGANLFVNTTSLGMGGTPVPDIDFSRLATG
                     ALVTDIVYVPLVTPIMAMAASQGLATVDGLGMLLHQAAPGFEKWFGRTPAVTKSLRDL
                     VIADIEAH"
     gene            143906..144499
                     /gene="coaE"
                     /locus_tag="HPDFL43_18722"
     CDS             143906..144499
                     /gene="coaE"
                     /locus_tag="HPDFL43_18722"
                     /EC_number="2.7.1.24"
                     /note="COG0237 Dephospho-CoA kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="ZP_02164562.1"
                     /db_xref="GI:163757473"
                     /translation="MIVIGLTGSIGMGKSTTAEMFKAAGVPVISADEIVHELYRGDAV
                     KLVEAAFPGSTSAGIVDRQALLEILLRDPAGFKRLEAIIHPLVREREHAFLNQARIDG
                     HAMALLDIPLLYETGGEKRVDTVVVVSCDPDIQRQRVLARPGMTEDKFDSIVARQLPD
                     AEKRARADFVIDTGKGLEPARWQVADIISQLGENHQD"
     gene            144509..145210
                     /locus_tag="HPDFL43_18727"
     CDS             144509..145210
                     /locus_tag="HPDFL43_18727"
                     /note="COG0847 DNA polymerase III, epsilon subunit and
                     related 3'-5' exonucleases"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="ZP_02164563.1"
                     /db_xref="GI:163757474"
                     /translation="MREIVFDTETTGLDNKVDRIIEIGCVELENQFPTGRSLHLFINP
                     DGRAVHPDALAVHGITDQFLADKPVFADLADEIAAFFDGAHYVAHNANFDMGFLNAEF
                     DRIGLPPVDPGLVIDTLALARRRHPMGPNSLDALCRRYGIDNAHRTKHGALLDAELLT
                     DVYIEMRGGRQAALGLSSAEAGNKTEESESVVIEIGERPGKLPERLTAGELEAHSTLV
                     NRIGADALWLKANRT"
     gene            complement(145302..145814)
                     /locus_tag="HPDFL43_18732"
     CDS             complement(145302..145814)
                     /locus_tag="HPDFL43_18732"
                     /note="COG1952 Preprotein translocase subunit SecB"
                     /codon_start=1
                     /transl_table=11
                     /product="export protein SecB"
                     /protein_id="ZP_02164564.1"
                     /db_xref="GI:163757475"
                     /translation="MAKDTTGAGAAAPADAKGNGAAPALNILAQYVKDLSFENPGAPK
                     SLGPRDKAPEININVNVNANPLGETEFDVVLTLNAEAKNGETVVFNVELVYGGVFRVA
                     NFPQEHMLPLLFIECPRLLFPFARQIVADATRNGGFPPLLIDPIDFAQMFQQRMAEEK
                     TKAQVENPVN"
     gene            complement(145911..146465)
                     /gene="fxsA"
                     /locus_tag="HPDFL43_18737"
     CDS             complement(145911..146465)
                     /gene="fxsA"
                     /locus_tag="HPDFL43_18737"
                     /note="COG3030 Protein affecting phage T7 exclusion by the
                     F plasmid"
                     /codon_start=1
                     /transl_table=11
                     /product="FxsA"
                     /protein_id="ZP_02164565.1"
                     /db_xref="GI:163757476"
                     /translation="MRFSFIPFLLLVIPLAEIAAFVVIGGQIGVWATLGMVLLTAAIG
                     SFLLRWQGVGLFNKINTELRANRVPGRELVHGVMILVAGVLLLTPGFVTDSLGFLLFV
                     PAFRDMVWRLVKDRIVVQTMSARHGGGPTGATRKSDDVVDLGEDEFERQGDPSSPWSE
                     DHGRGGGETGSQERLPGRDTKKRE"
     gene            146598..147302
                     /locus_tag="HPDFL43_18742"
     CDS             146598..147302
                     /locus_tag="HPDFL43_18742"
                     /note="COG4395 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164566.1"
                     /db_xref="GI:163757477"
                     /translation="MGSFDFVTFFFFVAAVIVFIQLRAVLGKRTGHERPPREQMERRD
                     QTDAQDGIDDPKVVTLPRRGREAAEPDAFAAVDAYAEPGSDLNKGLRELVKADPSFNP
                     KEFVGGATMAYEMIVSAYADGDRKTLKSLLSREVFDGFVSAIDEREARGETVRSNFVG
                     IEKANIIQAEMKGTEANVTLRIISQLISATLDKDGEVVEGDLVEVTDVNDVWTFTRDT
                     RSRDPNWRLIATEADQ"
     gene            147302..148426
                     /locus_tag="HPDFL43_18747"
     CDS             147302..148426
                     /locus_tag="HPDFL43_18747"
                     /note="COG2821 Membrane-bound lytic murein
                     transglycosylase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lytic murein transglycosylase a
                     protein"
                     /protein_id="ZP_02164567.1"
                     /db_xref="GI:163757478"
                     /translation="MPLSLRREGFSQLPGWAADSPATAFVAFCRSARYALEVTPYKSG
                     SLGLSAVEFEPVFQAALEVENRQSGRLSDQEARAFFEHWFQPLEILTDEAPGHVTGYY
                     EPEIEIRTEPDGIFRYPFLRRPVALSKVPDPEKPPIGIPQGYAFMLETEGGVRPCPDR
                     REIESGAFDGQNLEIAWATSRVDVFFAHVQGCARLTCPGQRTRRITYDGKSGHPFTGI
                     GRLLIERGEISRDAISMASIRHWLAQHPELADELMWQNRSFIFFREAEVTEERLGPVA
                     AAKVPLEPGRSLAVDRHVHSFGTPIFVVAPQLEDFDAARPFARLMIAQDTGTAIVGPA
                     RGDLFAGCGPQAGEKAGSINTGARFFILAPKESGCARRAH"
     gene            148386..149006
                     /locus_tag="HPDFL43_18752"
     CDS             148386..149006
                     /locus_tag="HPDFL43_18752"
                     /note="COG2840 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="putative Smr domain protein"
                     /protein_id="ZP_02164568.1"
                     /db_xref="GI:163757479"
                     /translation="MHPRNLAARGGPIDEWFVMSDDKRNLSHEDRIIWARIARTVEAY
                     PGKSVEEDDWFLKEDPASPAISAKSERPDLQPSSRPVPIPKPEVSQRPKHHPIEKPVV
                     RKLARGRLPIDGRIDLHGLTQSEAHNLLFDFIARAHERGLRHVLVITGKGSSRGSQGV
                     LKRLVPEWLAKPEFRFLISGHEDAARSHGGEGALYIRLRRERGGPR"
     gene            149003..149422
                     /locus_tag="HPDFL43_18757"
     CDS             149003..149422
                     /locus_tag="HPDFL43_18757"
                     /note="COG1396 Predicted transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, XRE family protein"
                     /protein_id="ZP_02164569.1"
                     /db_xref="GI:163757480"
                     /translation="MTPFGEAVRKLRAERGVTQRHMAEALGVSPAYLSALEHGKRSEP
                     SWEFIQRVIGYFNIIWDEAEELQMLAGLSRPKVTIDTAGLSSKATEIANRLAAVMARL
                     EPETLDDIAKLIEPIERNNSPAGSHPIRSGFGDKLPR"
     gene            complement(149448..150437)
                     /locus_tag="HPDFL43_18762"
     CDS             complement(149448..150437)
                     /locus_tag="HPDFL43_18762"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164570.1"
                     /db_xref="GI:163757481"
                     /translation="MIVARNMLKTVIAISAAFVVSIAPLSAAIAVEVVPAGNRNAKQP
                     EIPGASKRRTQATKSSFDEKYEKIRDLIAGDDKLKRKIRSVSKLYKIDPIHIVGALVG
                     EHTYNVDAYDRLQTYYIKAVSYAGERFRFEYDGETVVNFVERPQFESCDEDAGSAEVW
                     TCREEIWESKFRGKTVDGKKFPNDRFGAVFFQPFFAGQTFGLGQLNPLTALMHSDRVS
                     KVSRYRKLSAANAAQVYEAIMEPDSTLAFMAASIVESIENYHDIAGFDISRNPGVTAT
                     LYNVGNSAKRARDLAETNRKRANRGQKRILPAENYYGWLVNHHEDELRETISN"
     gene            complement(150552..151862)
                     /locus_tag="HPDFL43_18767"
     CDS             complement(150552..151862)
                     /locus_tag="HPDFL43_18767"
                     /note="COG1220 ATP-dependent protease HslVU (ClpYQ),
                     ATPase subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ATP-dependent heat shock protease
                     component"
                     /protein_id="ZP_02164571.1"
                     /db_xref="GI:163757482"
                     /translation="MTTFSPRETVTELDRFIIGQKDAKRAVAIALRNRWRRQQLTGPL
                     REEVMPKNILMIGPTGVGKTEISRRLARLAGAPFIKVEATKFTEVGYVGRDVEQIIRD
                     LVEAGIMLVRERKRGEVEAKARLNAEERVLDALVGATASPATRDSFRKKLRDGLLDDK
                     EIEIEVADNSAGGMPQFDLPGMPGGNIGVLNLNDLFGKAMGGRTRKIKTTVRDSYDTL
                     IGDESDKLLDMDQIHQEALKSAEDDGIVFIDEIDKIANREGGMGAGVSREGVQRDLLP
                     LVEGTTVATKYGPVKTDHILFIASGAFHVSKPSDLLPELQGRLPIRVELRALTKDDFR
                     RILTETEASLIKQYVALMGTEDMTLEFTEDAIDALAEVAVHLNGSIENIGARRLQTVM
                     ERVLDDISFTAPDQSGSTITIDSDYVRKNVGDLAQNTDLSRFIL"
     gene            complement(151870..153033)
                     /locus_tag="HPDFL43_18772"
     CDS             complement(151870..153033)
                     /locus_tag="HPDFL43_18772"
                     /note="COG0591 Na+/proline symporter"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164572.1"
                     /db_xref="GI:163757483"
                     /translation="MIDETTLDLAVTRGVLDADQRQALIALAKENRPAAEVDRGDADP
                     SVDDQMRLVGGGNDIFVTVGIILLFSGALFALQSVFAPGDNLIWVIMAISSWLVAEIV
                     TRQKRMRLSSTLLALVFVFAAASLLTELLAGRISIPSQINAFSLMALRSEAGQVALIL
                     GGGLIAAAAVYFFRFKVPVLAGVIAIAVTGLGFLGAIVFYHDQLISGAVAAPIPEQLA
                     DVVANALIIPLVCGLLIFAVAVAFDLRDRERQTVWSDCAFWLHVVSAPLLVHPLFILS
                     TGQEVLSGQIEPGISASILLGLMITTFVIVALAIDRRSLLAPTLAYFGSVGIYYLING
                     AANTTGIPPFALILIVIGAVVILFGAGWQRIRRLIIKPLVPTSILDRLPPIKA"
     gene            complement(153023..153568)
                     /locus_tag="HPDFL43_18777"
     CDS             complement(153023..153568)
                     /locus_tag="HPDFL43_18777"
                     /note="COG1670 Acetyltransferases, including N-acetylases
                     of ribosomal proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="GCN5-related N-acetyltransferase"
                     /protein_id="ZP_02164573.1"
                     /db_xref="GI:163757484"
                     /translation="MSAHDYELLENWMRRSHWQEWWGEAETELGYVRDMVEGRDTTRP
                     YLFALDGEPAGYIQAWMIGDHLTEPWLSETPWLRDVPSDSIGIDLAIGDVENLSRGLG
                     TAALKAFAKMLIEEGHRHILIDPDAANLRAIRAYQKAGFEQLLIAPDPEHEGQSTMIM
                     QLSIDGNQAQSGNQTGIQHDR"
     gene            complement(153594..154154)
                     /locus_tag="HPDFL43_18782"
     CDS             complement(153594..154154)
                     /locus_tag="HPDFL43_18782"
                     /EC_number="3.4.25.-"
                     /note="COG5405 ATP-dependent protease HslVU (ClpYQ),
                     peptidase subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease peptidase subunit"
                     /protein_id="ZP_02164574.1"
                     /db_xref="GI:163757485"
                     /translation="MSEHNPFGQMHATTIITVRKGNQVVMAGDGQVSLGQTVMKGNAR
                     KVRRIGKDNSVVAGFAGATADAFTLLERLEAKLEQYPDQLTRAAVELAKDWRTDRYLR
                     RLEAMMLVADKTVTLAITGNGDVLEPEHGTMAIGSGGNYAYAAARALMDGDKSAEEIA
                     RRAMEIAGDICVYTNTNIVIETLELD"
     gene            154366..154974
                     /locus_tag="HPDFL43_18787"
     CDS             154366..154974
                     /locus_tag="HPDFL43_18787"
                     /note="COG0131 Imidazoleglycerol-phosphate dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase"
                     /protein_id="ZP_02164575.1"
                     /db_xref="GI:163757486"
                     /translation="MATTESARAASIARKTNETDISVSLSVDGTGTGSISTGVGFFDH
                     MLEQLSRHSLIDLEIKAKGDLHIDDHHTVEDTGIAIGQALAKALGDRKGITRYASLDL
                     AMDETLTRAAVDISGRPFLVWDVNFSAPKIGTFDTELVREFFQALAQHGGITLHVTNL
                     YGANNHHIAETCFKAVARVLRTACEVDPRQKDRIPSTKGSLA"
     gene            155023..155505
                     /locus_tag="HPDFL43_18792"
     CDS             155023..155505
                     /locus_tag="HPDFL43_18792"
                     /note="COG0240 Glycerol-3-phosphate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164576.1"
                     /db_xref="GI:163757487"
                     /translation="MSCYLVFARPGAPVPDEGSVIVADRFAPWAFAFPMLWLLFNRLW
                     IEAAIAFALSLASTMMITNPALFWPGLALGVALSAVTAMEGRNWRAAALVRRGWQMID
                     LIEADDADAAFEIHALRASGGKTVVPGDRPTPPRNFPQPGRADESDAGTIGLVPVQRS"
     gene            155511..156161
                     /locus_tag="HPDFL43_18797"
     CDS             155511..156161
                     /locus_tag="HPDFL43_18797"
                     /note="COG0118 Glutamine amidotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol phosphate synthase subunit
                     (IGP synthase glutamine amidotransferase subunit) protein"
                     /protein_id="ZP_02164577.1"
                     /db_xref="GI:163757488"
                     /translation="MRVVVVDYGSGNLRSAVKAFERAARESGVSAEIILSAEADQVAN
                     ADRVVLPGVGAYADCRAGLNAIDGMADALRHAVEDKARPFLGICVGMQLMSTRGLEKT
                     TSEGFNWISGDVVEIAPSNPALKIPQIGWNTLDLQAQHPLFEGIPTGPDGLHAYFVHS
                     YHLAAKKSADVIATCDYGGTVTAAVAHENKAGTQFHPEKSQTLGLALIANFLKWKP"
     gene            156163..156933
                     /locus_tag="HPDFL43_18802"
     CDS             156163..156933
                     /locus_tag="HPDFL43_18802"
                     /EC_number="5.3.1.16"
                     /note="COG0106 Phosphoribosylformimino-5-aminoimidazole
                     carboxamide ribonucleotide (ProFAR) isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]
                     imidazole-4-carboxamide isomerase"
                     /protein_id="ZP_02164578.1"
                     /db_xref="GI:163757489"
                     /translation="MILFPAIDLKDGQCVRLKLGEMASATVYNEDPAAQARAFEDQGF
                     EWLHVVDLNGAFEGQSVNGAAVEAILKATKNPVQLGGGIRTLAHIESWLDKGLARVIL
                     GTIAVRDPDLVREACKRFPGRVAVGIDAKGGKVAVEGWAEASELGVIELAKRFEGAGV
                     AAIIYTDIDRDGVLAGINWESTIELAGAVSIPVIASGGLASIADIVRMKMPDAARLEG
                     AISGRALYDGRIDPAEALGVLNGTLTLEPAKFEQEDRS"
     gene            156930..157706
                     /locus_tag="HPDFL43_18807"
     CDS             156930..157706
                     /locus_tag="HPDFL43_18807"
                     /EC_number="4.1.3.-"
                     /note="COG0107 Imidazoleglycerol-phosphate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="ZP_02164579.1"
                     /db_xref="GI:163757490"
                     /translation="MTLKSRVIPCLDVKDGRVVKGVNFVDLIDAGDPVEAAKAYDAAG
                     ADELCFLDITASSDNRETIFDVVAQTAEHCFMPLTVGGGVRAVADIRKLLLAGADKVS
                     INTAAVNNPDFVAEAADKFGNQCIVVSVDAKKVSGPNETDRWEIFTHGGRTPTGIDAV
                     GFAERMVQLGAGELLLTSMDRDGTKSGFDIGLTRTIADAVRVPVIASGGVGTLDHLVE
                     GIRDGHATAVLAASIFHFGTYTIGEAKQHMAAAGLDMRLD"
     gene            157759..158082
                     /gene="hisE"
                     /locus_tag="HPDFL43_18812"
     CDS             157759..158082
                     /gene="hisE"
                     /locus_tag="HPDFL43_18812"
                     /EC_number="3.6.1.31"
                     /note="COG0140 Phosphoribosyl-ATP pyrophosphohydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-ATP pyrophosphatase"
                     /protein_id="ZP_02164580.1"
                     /db_xref="GI:163757491"
                     /translation="MTSFTLADLEKIVAVRAAADPAESWTAKLAAAGMPKAAKKLGEE
                     AVETVIAATSQGRGELVGESADLLYHLLVVLRIGNIPLNEVMAELQRRTAQSGLAEKA
                     GRPVE"
     gene            158085..159071
                     /locus_tag="HPDFL43_18817"
     CDS             158085..159071
                     /locus_tag="HPDFL43_18817"
                     /note="COG1072 Panthothenate kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="pantothenate kinase"
                     /protein_id="ZP_02164581.1"
                     /db_xref="GI:163757492"
                     /translation="MDQTDIQPRTLDHFTGDDFSPYRFFSAEKWAEFRADTPLTLSED
                     EVRKLRSLNDPVDLDEVRRIYLSLSRLLSAHVESSQLLFEQRKRFLNLSDVVKTPFII
                     GIAGSVAVGKSTTARVLAQLLSRWPSSPKVDLVTTDGFLYPNEVLRRENLMDRKGFPE
                     SYDVGAVLRFLSEIKAGQHNVHAPCYSHLTYDVLPGEHTVIDRPDILIFEGINVLQVR
                     DLPEDGKIVPFVSDFFDFSIYIDAEEADIHKWYVDRFMNLRQTAFRDPDSFFHRYATI
                     NEDAALAIAESLWENINLKNLRQNILPTRPRADLILRKAPNHLIEQVALRKL"
     gene            complement(159086..159694)
                     /locus_tag="HPDFL43_18822"
     CDS             complement(159086..159694)
                     /locus_tag="HPDFL43_18822"
                     /note="COG3145 Alkylated DNA repair protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alkylated DNA repair protein"
                     /protein_id="ZP_02164582.1"
                     /db_xref="GI:163757493"
                     /translation="MLVLPKGVRHIPGHLDRDEQTSLVEDIRAVVRQAPLYRPEMPRT
                     GKPLSVRMTNCGTLGWVSDKAGYRYQDSHPVSGAPWPPVPNRLKALWADLTGESRPPQ
                     ACLINYYDVSARMGLHQDRDESDFSAPVLSVSLGDACLFRIGGTERGQPTRSFRLESG
                     DVVILGGESRLAFHGVDRIYPMTSTLLKDGGRINLTLRRVDS"
     gene            complement(159722..160237)
                     /locus_tag="HPDFL43_18827"
     CDS             complement(159722..160237)
                     /locus_tag="HPDFL43_18827"
                     /note="COG1652 Uncharacterized protein containing LysM
                     domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164583.1"
                     /db_xref="GI:163757494"
                     /translation="MGIFDFIKSAGKKLGIGGDDDAPEADAVKKELDSFGLGTDKVDV
                     KVDGDKVVLSGVVEDQSIFEKAIVAVGNTLGISKVEASELKVVLPDSGLKLADVDMTA
                     LVAASTPANEPKFHTVQKGDSLWKVAEAAYGKGKGGKYKVIFEANKPMLSDPDKIYPG
                     QVLRIPDIETA"
     gene            complement(160317..160751)
                     /locus_tag="HPDFL43_18832"
     CDS             complement(160317..160751)
                     /locus_tag="HPDFL43_18832"
                     /note="COG1186 Protein chain release factor B"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164584.1"
                     /db_xref="GI:163757495"
                     /translation="MSTDALYAARGIVIAHWELSESFIRASGPGGQNVNKVATAVQLR
                     FDITNSPSLTDRVKANAIRLGGSRVSKEGVLILEANRFRTQERNRADARERLVELLDK
                     ASAPPPPPRRKTKPTRGSVERRLAAKSGRAVIKKARQKVRDD"
     gene            complement(160748..161425)
                     /locus_tag="HPDFL43_18837"
     CDS             complement(160748..161425)
                     /locus_tag="HPDFL43_18837"
                     /note="COG0778 Nitroreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="ZP_02164585.1"
                     /db_xref="GI:163757496"
                     /translation="MAKTAETIELSLPRLSEADMLAEARAFHDRLQSRRTVRDFSPEP
                     VDPELIRIAVRTAGTAPSGANQQPWSFVAIGDPDTKRAIRLAAEEEERTFYKSRAGDE
                     WLDALAPLGTDADKPFLETAPWLIAIFAQRWGVDAKGRKIKHYYVPESVSIAIGLLIA
                     SLHSAGLATLTHTPSPMGFLNQICGRPENEKPLVLLVVGHPAKGARVPAISRKDESQI
                     LFWKVDR"
     gene            complement(161526..163121)
                     /locus_tag="HPDFL43_18842"
     CDS             complement(161526..163121)
                     /locus_tag="HPDFL43_18842"
                     /note="COG1866 Phosphoenolpyruvate carboxykinase (ATP)"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase"
                     /protein_id="ZP_02164586.1"
                     /db_xref="GI:163757497"
                     /translation="MRNPSASLALCGLETTGVVRYNLGEAELVELAVANGEATLTAHG
                     ALRALTGQHTGRSAKDKFVVRDASTEDQIWWDNNKPMAPEAFETLHADMIAHARERDL
                     FVQDLVGGADSAHALLSRIVTEYAWHALFIRNLLIRPERAALAGFMPELTIINLPSFR
                     ANPERHGCRSETVIAVNLAKGLVLIGGTSYAGEMKKSVFTALNYLLPAKNVMPMHCSA
                     NAGPDGDTAVFFGLSGTGKTTLSADPARTLIGDDEHGWGEDGVFNFEGGCYAKTIRLS
                     REAEPEIFGTTERFGTVLENVVLDENRIPDFDDGSLTENTRCAYPLHFIPNASSTGRA
                     GHPRNIIMLTADAFGVMPPIAKLTPEQAMYHFLSGYTAKVAGTEKGVTEPEATFSTCF
                     GAPFMPRHPSEYGALLRKLINDHRVNCWLVNTGWTGGAYGQGQRMPIKATRTLLTAAL
                     NGSLETAEYRNDPNFGFAVPVTVSGVDSTILDPRSTWSDKHAYDAAADRLVGMFIDNF
                     EKFESHVDGSVLTAAPGFKAAAE"
     gene            163467..164198
                     /locus_tag="HPDFL43_18847"
     CDS             163467..164198
                     /locus_tag="HPDFL43_18847"
                     /note="COG0745 Response regulators consisting of a
                     CheY-like receiver domain and a winged-helix DNA-binding
                     domain"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator protein"
                     /protein_id="ZP_02164587.1"
                     /db_xref="GI:163757498"
                     /translation="MTETTIMQTIALVDDDRNILTSVSIALETEGYRVETYTDGASAL
                     DGLLARPPQLAIFDIKMPRMDGMELLRRLRQKSDIPVIFLTSKDEEIDELFGLKMGAD
                     DFITKPFSQRLLVERVKAVMRRAASRDAAAAPGRAAATPTKSLERGNLVMDQERHTCT
                     WKNEAVTLTVTEFLILQSLAQRPGVVKSRDALMDAAYDEQVYVDDRTIDSHIKRLRKK
                     FKMVDDDFDMIETLYGVGYRFREAA"
     gene            164258..166042
                     /locus_tag="HPDFL43_18852"
     CDS             164258..166042
                     /locus_tag="HPDFL43_18852"
                     /note="COG0642 Signal transduction histidine kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase sensory transmembrane protein"
                     /protein_id="ZP_02164588.1"
                     /db_xref="GI:163757499"
                     /translation="MAIETEDNLRSEADHSAAATRQKNWIHPVTLVRRIFGHLIFSSL
                     TRRILFLNLAALIVLVSGILYLNQFREGLIDARVESLLTQGEIIAGAVAASASVETNS
                     ITIDPEKLLELQAGQTISPTNSNENLDFPINPERVAPVLRRLISPTRTRARIYDDDAS
                     LILDSRYLYTSGQVLRYDLPANEVTQRSLTESLGAWFNRFFQRSDLPLYREPPGADGS
                     IYPEVMNALAGGRGAVVRVTEAGELIVSVAVPVQRFRAVLGVLLLSTQAGDIDKIVHA
                     ERMAIFRVSGVAFMVSSVLSLLLASTIATPLRRLSAAAVRVRRGVKAREEIPDFSDRQ
                     DEIGNLSVALRDMTNALYDRIDAIESFAADVSHELKNPLTSLRSAVETLPLARNEHSR
                     KRLLDVILHDVRRMDRLISDISDASRLDAELARQDGATVDMRTLLTDLVEIARQVRAG
                     SKKVAIDLKVDGKAGDKTKFIIVGHDLRLGQVVTNLIENARSFVPETDGRIVVRLARR
                     RGAVRVLIEDNGPGIRAEVIERVFERFYTDRPDGEDFGQNSGLGLSISRQIIEAHGGT
                     LTAENIAPQTDGKWAGARFIIELPAEQL"
     gene            166072..166509
                     /locus_tag="HPDFL43_18857"
     CDS             166072..166509
                     /locus_tag="HPDFL43_18857"
                     /note="COG1493 Serine kinase of the HPr protein, regulates
                     carbohydrate metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164589.1"
                     /db_xref="GI:163757500"
                     /translation="MHATAIVVGETGILFVGPSGAGKSTMAFACLAGAISRGWNAALV
                     ADDRTCLTVHSGRCIASCPEPIRGKLELRGGGIVDLPRIGRAVMHLAVAPGPPSVKSR
                     LPPDNEIFTCDGVELHLQRLWRDGATDPLTALCALRPDRFLSN"
     gene            166665..167066
                     /locus_tag="HPDFL43_18862"
     CDS             166665..167066
                     /locus_tag="HPDFL43_18862"
                     /note="COG2893 Phosphotransferase system,
                     mannose/fructose-specific component IIA"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system, IIA component"
                     /protein_id="ZP_02164590.1"
                     /db_xref="GI:163757501"
                     /translation="MIGLVLVTHGKLAEEFRHALEHVVGPQTALETVCIGPEDDMDQR
                     RMDIVGAVSRVESGKGVIILTDMFGGTPSNLSISVMDSGRIEVIAGVNLPMLIKLAGI
                     RGANDIDNALAQAQDAGRKYINVASRLLAGK"
     gene            167063..167350
                     /locus_tag="HPDFL43_18867"
     CDS             167063..167350
                     /locus_tag="HPDFL43_18867"
                     /note="COG1925 Phosphotransferase system, HPr-related
                     proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="ZP_02164591.1"
                     /db_xref="GI:163757502"
                     /translation="MTTQATVQSRTLKIINKRGLHARASARFVQTVEGYDATVRVTRE
                     GSTVGGTSIMGLMMLAASPGCSIEVEVEGRQATEVLDALEALVKDRFGEDE"
     gene            167469..168863
                     /locus_tag="HPDFL43_18872"
     CDS             167469..168863
                     /locus_tag="HPDFL43_18872"
                     /EC_number="3.3.1.1"
                     /note="COG0499 S-adenosylhomocysteine hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-L-homocysteine hydrolase"
                     /protein_id="ZP_02164592.1"
                     /db_xref="GI:163757503"
                     /translation="MTATNDYVVADIALADFGRKELDIAETEMPGLMALREEYGSSQP
                     LKGARIVGSLHMTIQTAVLIETLTSLGADVRWASCNIYSTQDHAAAAIAKSGVPVFAI
                     KGQTLEEHWDYLDKSFMFADGPNLILDDGGDATLYVLLGARAEAGEDIIPVPASEEEE
                     VIKAQIKKRMAASPGWFTKIRDQIVGVSEETTTGVHRLYELHKKGLLPFPAINVNDSV
                     TKSKFDNKYGCKESLVDGIRRATDTMMAGKVAVVCGYGDVGKGSAASLRGAGARVKVT
                     EVDPICALQAAMDGFEVVTLEDVASDADIFITTTGNKDVIRLEHMREMKDMAIVGNIG
                     HFDNEIQVAALKNHKWTNIKDQVDMVEMPSGNRMILLSQGRLLNLGNATGHPSFVMSA
                     SFTNQVLAQMELWTKGDEYKNEVYVLPKHLDEKVARLHLDKIGAKLTSLQPEQADYIG
                     VTVEGPFKPEHYRY"
     gene            168977..171586
                     /locus_tag="HPDFL43_18877"
     CDS             168977..171586
                     /locus_tag="HPDFL43_18877"
                     /note="COG0642 Signal transduction histidine kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sensor histidine kinase protein"
                     /protein_id="ZP_02164593.1"
                     /db_xref="GI:163757504"
                     /translation="MMIRFRVWRRGKWIGDVLSNRRRGDGDMPVKADSQQIDSKPGSE
                     GTWTGGLKRLYRRFLTGTALVGGGFLLPFSHAFAQSAGGFKISSLEVVNFAMVIGAIS
                     AAMISAIWLIRERAKIDAENVALRTALADSHAQLSRYQSLIVDRDRQIVVWDGVGVPA
                     EVLGNLSPATGAPQKPDDFLAFGRWLEPRSAASLNESIDLLRAQAERFDLIVETVRGH
                     VIEAQGRVSGGRAFVRFVALSNVRAELAELKTERDRLLASVDTFQTLLDVIDMPAWLR
                     GSDAKLLWVNNAYVRAVEGPDRSDTIERGMELLGTAAREKIRAAATPERPFLDRVSTV
                     IQGHRRFLEVADVKTPGGNAGLALDVSVEEDLREELRRTIQSHSETLDHLATPVAIFD
                     RDQRLQFHNQAFQQLWELDIPFLARRPDNGEFLERLRADGKLPEPHAWRDWKEQMLSV
                     YRSVETTPHLWHLPDGQTLNVFANAHPQGGVTWVFENLTEKVDLETKYNTLLQVQGET
                     IDHLAEGVGVFGPDGRIRLSNPSFRALWGLTEEQVKPGTHIRDITAACEPSYREPDGW
                     KLFAGEITSFNEERRSRDGRIELVTGLILDYAVVPLPNGQTMVAFVNVTDSVDAERML
                     TETNEALRKADALKNDFVNHVSYELRSPLTNIIGFTDLLKTPGVGDLTERQAEYLDHI
                     STSSSVLLTIVNDILDLATVDAGIMQLEIAEVNIDTLLSEAADQIADWFKENGLKLET
                     ESANAPATMMGDYQRLKQILFKLLMNAANFAPEGSVVRLGCAMEDESIVFSVADSGPG
                     IPESARKDVFARFETHGQGGRRRGAGLGLSIVQSFVSLHNGTVSVEDSEGSGTTILCR
                     FPTKAPQLRDAAE"
     gene            171608..173101
                     /locus_tag="HPDFL43_18882"
     CDS             171608..173101
                     /locus_tag="HPDFL43_18882"
                     /note="COG0802 Predicted ATPase or kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164594.1"
                     /db_xref="GI:163757505"
                     /translation="MIFSLADLAATTRFAEDMALSLKPGDCLCLSGDLGAGKTTFARA
                     LIRAVADDPDLEVPSPTFTLVQVYELRLPIAHFDLYRLGSAEELDELGLEDALSDGAA
                     LIEWPEQAAERLPQNLVEIRFAGLDATRTATVSANTDFLDRLKRSCAVRAFLEQAGLL
                     AAERRHLQGDASSRTYEMVRADGKDPVILMNAPHRPDGPPIRDGLPYSRIAHLAEDVV
                     PFVAIAQWLHEQGFAAPEILAEDLDQGFLLVEYLGSGGLLDEQGAPVAERYQLAVDCL
                     AALHGKTPPTTIPIAGAEHHVPAYDPRAMQIEIELLTDWYLPWRTGHPLPDSDRQEYL
                     AIWSGLFSSLEAAEKALVLRDYHSPNLIWRSERQGFDRLGIIDFQDAMIGPSAYDVAS
                     LCQDARVTIEPELAEKLLARYIAARHEVDPAFDEAAFREAYAIMAAQRAAKILGIFVR
                     LDQRDGKPAYLRHLPRIEAYIAQSLNHPALRPLRSWFTRVGIGETES"
     gene            173115..173873
                     /locus_tag="HPDFL43_18887"
     CDS             173115..173873
                     /locus_tag="HPDFL43_18887"
                     /note="COG1208 Nucleoside-diphosphate-sugar
                     pyrophosphorylase involved in lipopolysaccharide
                     biosynthesis/translation initiation factor 2B,
                     gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="ZP_02164595.1"
                     /db_xref="GI:163757506"
                     /translation="MRINSAMILAAGLGTRMRPITETLPKPLVEVAGKPLIAYSLEAL
                     DRIGVTSIVANVHYLAPMLTKWLKDWPGAEIAISDETETLLDSGGGIVKALPQLGPYP
                     FLVLNADTFWLEDPDAGSDNLARMADQFDPAIMDIMMMTARLDQATGHTGAGDFTIDP
                     EGRLARYRGSGDPVIYAGALVLSPHIFDAISEPKFSLNRCFDAAIESGRLFGAPMLGH
                     WLTVGTPAAIGEAEAAMSAYLNGSASSTGHRPNR"
     gene            173870..177076
                     /locus_tag="HPDFL43_18892"
     CDS             173870..177076
                     /locus_tag="HPDFL43_18892"
                     /note="COG3893 Inactivated superfamily I helicase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164596.1"
                     /db_xref="GI:163757507"
                     /translation="MTRSAPHIVTIPPGAPFLSVLVEKIHGGGLIDGLAYRPEDPLSL
                     ARATIFVPTRRAARALRSELTDRIGVGSAILPSIRPLGETDEDAGFFDSADPATLSLD
                     PAIPQTAATLRLADLVLAWKKALPRAVLDHLGGAPLVAPANPADAIWLGRSLFDLIQA
                     VETEECDFAGLDQVVSEDLQQWWQLTREFLAIAREYWPALLTEISRSSPAGHHNAMID
                     VFTRALTTDPEDRPVIVAGSTGTRPSTARLIAAIAHLPRGAVVLPGLDHAMGLSHWQD
                     LAKSVSVTAPPGTPVSFDPAARSHPQYGLLRLLESCGVDIASLGDIPEIAMLEGAMEV
                     RRAAVSAALLPAGTTEAWGEPGFLPDASALSQAFASVSLIEAANEREEAAALAAAMRQ
                     ALEPGSKSAEPVVALVTPDRNLARRVVVELQRYGIEANDSGGIPLMSSPQGGLVRLAV
                     QVAFAPGDAVAITALIKHPLARFGLDQQSAQQLAGIVERIALRGGSGEADVDQLETLV
                     AERSEARKKPHAARWLTRISDQDAEAARDFAARVADALSPLTSILVEAPGQRFSNAVD
                     IGGLAGLTAETLEKICSDETGSLEPLWGDEAGEVLSNILLETRDSGSTLTITGHEWIG
                     ALDALISGRMVKPRTGGHPRAFIWGALEARLQHVDTILLGALNEGVWPQAGQEDPFLS
                     RSMKAAMGLEPPERRIGQAAHDFQMAMGAPQVVLSRANRSGKAPTVASRWLQRLLAVA
                     GSDTATALRHRGDALLDHVRSLDQATPVSPAIRPEPKPPAQMQPQSYSFSEVATLRRD
                     PYAIYARRVLRLDPLEPFLTDPGPRERGTLYHAILEQFIASRAPGDRTLEALREIAAA
                     HFLDAELPDATALIWQSRFDKAAAAIAGWEAGIASGHGRSVVEARASLEMPLAGIRLT
                     GMADRIDLRADGTAWIIDYKTGGTPSRKQARTLLDPQLALEAHALRQGGFADLGALPA
                     SALLYLRLTGKDPFAERVDNDPEKPGRDEFLNPDELAQKAADELTWLVTLLRSGKRGF
                     LSRAIPKSVRDFAGDYDHLARVAEWQTVVDAEGGDGDD"
     gene            177063..180653
                     /locus_tag="HPDFL43_18897"
     CDS             177063..180653
                     /locus_tag="HPDFL43_18897"
                     /note="COG1074 ATP-dependent exoDNAse (exonuclease V) beta
                     subunit (contains helicase and exonuclease domains)"
                     /codon_start=1
                     /transl_table=11
                     /product="probable nuclease/helicase protein, ATP
                     dependent"
                     /protein_id="ZP_02164597.1"
                     /db_xref="GI:163757508"
                     /translation="MAMTETNGTDVISQTTLRQNRAATPQLSAWVSANAGSGKTHVLA
                     RRVIRLLLRGARPSAILCLTYTKAAAAEMSNRVFKTLADWVLLDDQALAEKLTELEGA
                     PTEPRTLILARRLFATALETPGGLKIQTIHAFCEAVLHRFPLEANIPGHFSVLDDQKA
                     AELLAEARRELMSAQAFEADPALADAVTQALDIGGESGFDKLLAGLYARRRDCLAFDA
                     AASKAGGADAMIRTALGLAEDEDETAIIAQAWPMEALPIDYVKDVFEFAGSAKSASKA
                     YDFTYGLVAAHSQTDPAERLDLLRQVFFTKSGPPSKLGSVASKSVAERFPDLADRAQA
                     AQAQIAGVFDRLARLKALDASLIAYHLARRYIGGFAAMKSRQALLDYDDLIAATASLL
                     EKSGASAWVHYKLDQGIDHILVDEAQDTAPLQWSVIGKLSEEFFAGEGARQARRTLFA
                     VGDEKQSIYSFQGARPERFAQERRSTQLKAEAAGVVFEHVPLRVSFRSSSEVLKLVDH
                     VFASADAMRGMGDPDEPVMHETARARAPGQAELWPMIAKQKSDDDDDWTAAFDDVPEA
                     APSAQLARRIATVLRDWIDNEMIEDQKTRKLRPITPGDVLVLVRKRDGFVPTLLRTLK
                     AMTGIPVAGADRLRLTDHIAVQDLMALGSFVLLDEDDLSLAALIKSPLLGLDEDALFR
                     LAAGRPDGLSVWNHLLELAKTEPLFASARNRLVRWRAMAHIQPPHDFYATVLGPDGGR
                     QAYLSRLGHEAGDVLDEFLGLTLDHEQAGLPGLQAFLAMLESDAPEIKREMEAGSGAV
                     RIMTVHAAKGLEAPIVFLVDSGGEAFQTSHQPNLWLIPQGPHQGSDGPSVPVWLPDKT
                     YNNGATNPLRELAKEQAEEEYRRLLYVGLTRAADRLVVCGYRGLKEAKSPTWHTLASA
                     GFERAAEAGDYAVGEIEREADNTTFPVLRLQRAAPAPVAPGEPAADSKERTAAPAPIP
                     SSPLPPPTRLPRPLAPSGVGAVLEDSANLANRSPFADKPAGSGAALERGSMIHRLLQV
                     LPSIPPEERDAALERYLERALPGADRSEAGLIAGQVRSVLDDARFAGVFAAQQGEAEV
                     SVMGTLRIAGEERAVSGRIDRIAVLADRVLIVDYKTGLAPGSGEPPPHSHVSQLAIYR
                     ALLAPLYPDRKIEAALIYVSGPVLVPIPETALDAAMMALEPRSRFEADAG"
     gene            180733..181056
                     /locus_tag="HPDFL43_18902"
     CDS             180733..181056
                     /locus_tag="HPDFL43_18902"
                     /note="COG0526 Thiol-disulfide isomerase and thioredoxins"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin C-1"
                     /protein_id="ZP_02164598.1"
                     /db_xref="GI:163757509"
                     /translation="MATVKVDSANFQSEVLDSSVPVVVDFWAEWCGPCKMIAPSLEEI
                     SNEMEGKVKVAKINIDENPEIASQFGVRSIPTLAMFKAGAVADIKVGASPKTALSSWI
                     SGAVA"
     gene            complement(181131..182477)
                     /locus_tag="HPDFL43_18907"
     CDS             complement(181131..182477)
                     /locus_tag="HPDFL43_18907"
                     /note="COG0285 Folylpolyglutamate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="probable folc bifunctional protein includes:
                     folylpolyglutamate synthase and dihydrofolate synthase"
                     /protein_id="ZP_02164599.1"
                     /db_xref="GI:163757510"
                     /translation="MTVEKSVVSATEQEINALMALHPKGFDLSLGRITRLLERLGNPH
                     QRLPPVIHIAGTNGKGSTGAFCRAILEAHGLTAHVHTSPHLVNWHERYRLGAEGGGQL
                     VSDDVLADAVRRVAEANQGETITVFEILTAVMFVLFSEHPADVAIIEVGLGGRFDATN
                     VISNPAVALIMSISLDHQAYLGDRVELIAAEKGGIIKADVPVVIGAQTEEAACDVLIS
                     IAERLRCPVSVYGQDYFAQEENGRLAYQDEEELIDLPLPRLAGRHQQSNAAAAIRALK
                     AAGFELDDTAIAKGLTQVSWPGRLERLPQGRLAEATMEGVELWIDGGHNPGAGKVIAE
                     AMANLEERDSRPLFLITGMINTKDPVGYFEAFVGMARHVFAVPVPASDASIDPELMAD
                     AADEAGLTAESAESVEAAIDAVTRNWNRLEPAPRILIGGSLYLLGDVLERNGTPPK"
     gene            complement(182528..183451)
                     /locus_tag="HPDFL43_18912"
     CDS             complement(182528..183451)
                     /locus_tag="HPDFL43_18912"
                     /note="COG0777 Acetyl-CoA carboxylase beta subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase beta subunit"
                     /protein_id="ZP_02164600.1"
                     /db_xref="GI:163757511"
                     /translation="MNWITNYVRPKINSMLGRREVPENLWIKCPETGEMVFHNDLEEN
                     HFVIPASGYHMKMSAEARLKHIFDDGKYELLPSPKVPQDPLKFRDSKKYTDRLRENRA
                     KTGLEDSVVAGHGAVRGVDIVACVHDFSFMGGSLGIGAGEAIIQAFEAAIERKCPLVM
                     FPASGGARMQEGILSLMQLPRTTVAVEMLKEAGLPYIVVLTNPTTGGVSASYAMLGDI
                     HLAEPGAEICFAGKRVIEQTIREKLPEGFQTSEYLLEHGMIDMVVHRHDLPETIARLL
                     RIFLKLDAPAPAALPAPVTEAAEEAPAEAAE"
     gene            complement(183539..184378)
                     /locus_tag="HPDFL43_18917"
     CDS             complement(183539..184378)
                     /locus_tag="HPDFL43_18917"
                     /note="COG0159 Tryptophan synthase alpha chain"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="ZP_02164601.1"
                     /db_xref="GI:163757512"
                     /translation="MTTRIDTRFEKLKAEGRPALVTYFMGGDPDYDTSLKIMQALPGA
                     GSDVIELGMPFSDPMADGPAIQMAGQRALKAGQTLSRTLDLARDFRKGDNETPIVLMG
                     YYNPIYIYGVERFLVDAREAGIDGLIVVDLPPEMDEELCLPALKAGLNFIRLATPTTD
                     DKRLPRVLSNTSGFVYYVSMTGITGSAIADTTKVNAAVDRIKSHTDLPICVGFGVKTA
                     EQARAIGKSADGVVVGTAIVNQIANTLDANNQATSDTVESVATMVRGLATGVREARLA
                     PAE"
     gene            complement(184381..185601)
                     /locus_tag="HPDFL43_18922"
     CDS             complement(184381..185601)
                     /locus_tag="HPDFL43_18922"
                     /note="COG0133 Tryptophan synthase beta chain"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase, beta subunit"
                     /protein_id="ZP_02164602.1"
                     /db_xref="GI:163757513"
                     /translation="MNQPSNPNSFRTGPDEQGMFGIFGGRFVAETLMPLILELEEEWT
                     KAKTDPAFQAELEHLNTHYTGRPSPMYFAERLTEHLGGAKIYFKRDELNHTGSHKINN
                     CVGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGYPCEVYMGATDVQRQAPNVFR
                     MKLLGAKVNPVSSGHGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPEMVRTFQS
                     VIGKETREQMLALEGRLPDMLIAAVGGGSNAIGLFHPFLDDKDVQIVGVEAGGKGLEG
                     EEHCASLTAGSPGVLHGNRTYLLQNGDGQIEEGHSISAGLDYPGIGPEHSWLKDSGRV
                     EYVPVMDDEALEAFQLLTRLEGIIPALEPSHALAEVIKRAPKMGKDQIIVMNLCGRGD
                     KDIFTVGKILGVEL"
     gene            complement(185622..186287)
                     /locus_tag="HPDFL43_18927"
     CDS             complement(185622..186287)
                     /locus_tag="HPDFL43_18927"
                     /EC_number="5.3.1.24"
                     /note="COG0135 Phosphoribosylanthranilate isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="N-(5'-phosphoribosyl)anthranilate isomerase"
                     /protein_id="ZP_02164603.1"
                     /db_xref="GI:163757514"
                     /translation="MTIPIKICGLSTPEAVDRAADLKADMAGFIFFPKSPRHVTVDDA
                     RQLAERARARELKTVAVTVDMDDAGLDEIVEQMKPDWLQLHGTETPERLSVLKVRYGL
                     PVMKALAVRDAGDLDRAAVYNGIADRMLFDAKPPKGSDLPGGNGVSFDWQLLAGRDLS
                     SLDGAASYMLSGGLTTDNVGEALRISGAPGVDVSSGVESAPGVKDLAMMGAFVQAVSN
                     APK"
     gene            complement(186397..187083)
                     /locus_tag="HPDFL43_18932"
     CDS             complement(186397..187083)
                     /locus_tag="HPDFL43_18932"
                     /note="COG1451 Predicted metal-dependent hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc metallopeptidase protein"
                     /protein_id="ZP_02164604.1"
                     /db_xref="GI:163757515"
                     /translation="MNGRELPLTIRENARATRMTLRIEPGGQALKLTIPRGLAVHEID
                     AFLTRHHGWLMTRLANASDTGPLIEIGKIVIRGVEHRIEMTGKLRGLAEETEIDGVPT
                     LMVSGSPEHTGRRVADHLKRVARRELEQLVAKHAATLGKPVRSISYKDTKSRWGSCTS
                     QGNLSFSWRIAMAPDFVIDYLAAHEVAHLKEMNHGPDFWATCKALCPRTNEAKRWLKQ
                     NGSRLFAVTF"
     gene            complement(187259..187693)
                     /locus_tag="HPDFL43_18937"
     CDS             complement(187259..187693)
                     /locus_tag="HPDFL43_18937"
                     /note="COG5444 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane protein"
                     /protein_id="ZP_02164605.1"
                     /db_xref="GI:163757516"
                     /translation="MTQTALIRPAWTPATIALMVLGFMVFWPLGLAMLAYIIWGDRLD
                     TFKADVNRATDDLASSFRKKSGHGTYASSGNAAFDDWRDNELSRLDEERKKLDEMRTE
                     FDQHMRDLRMARDRQEFEQFMADRQARQSKTKKGRSVPEIDG"
     gene            complement(187856..189139)
                     /locus_tag="HPDFL43_18942"
     CDS             complement(187856..189139)
                     /locus_tag="HPDFL43_18942"
                     /note="COG4553 Poly-beta-hydroxyalkanoate depolymerase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164606.1"
                     /db_xref="GI:163757517"
                     /translation="MFYQMYELNHAAVAPMRAYADAMRLAFRNPINPLSHTPFGRAMG
                     AGFELFERTTRRYSKPEFGLNETSLNSGKVSVHEKVVWSRPFCDLIHFERTLPANHRP
                     DPKILIVAPMSGHYATLLRGTVETLLPKAEVYITDWTDARMVPLSEGRFDLDDYIDYV
                     ISMLHALGPDTHVLAVCQPSVPVLAAVAIMEESGDKFAPSSMTLMGGPIDTRINPTGV
                     NELAQTKPIEWFEENVIMQVPWPLPGFTRAVYPGFLQLSGFMTMNLDRHMIAQKDFFL
                     HLVKDDGDSAERHRDFYDEYLAVMDMTAEFYLQTVDTVFIKHSLPKGEMMHRGRKVDT
                     TAIRNVALLTVEGENDDISGLGQTEAAQTICPNIPDEMRYHYVQPKVGHYGVFNGSRF
                     RAEIAPRILDFMRSHGKANRAKRGAPKLIKGGKSA"
     gene            complement(189364..190365)
                     /locus_tag="HPDFL43_18947"
     CDS             complement(189364..190365)
                     /locus_tag="HPDFL43_18947"
                     /note="COG0451 Nucleoside-diphosphate-sugar epimerases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164607.1"
                     /db_xref="GI:163757518"
                     /translation="MNEDGIIHSTQEMMMKTIAVLGARGRVSRVVARTFLDRNWRVIA
                     VTRDGKLPQGLARAEGRSADAMDQAALIAACRGADVIFNGLNPVYTDWAEIVPVFTAN
                     VIAAAKATGALHLLAGNVYNYGRSIPAIADETTPMPGDTGKGMIRNAMEKTFERAAGD
                     GVKTTIVRAGDFYGGDGRGAWFDLGITVKLDKGIFTWPGAMDIDHAWAYLPDLAETFV
                     KIAETGGDGSGFATYTFEGHTLSGTQMKKLIEKALGGKSLKRSSIPWLLLRAAGLVVP
                     KWREVVEVSYLWFTPHRLSGKRLEAAIGPLAKTSPDTAIAEALAELGFATTKSNLVA"
     gene            190441..191322
                     /locus_tag="HPDFL43_18952"
     CDS             190441..191322
                     /locus_tag="HPDFL43_18952"
                     /note="COG0583 Transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="ZP_02164608.1"
                     /db_xref="GI:163757519"
                     /translation="MDWNLLRSFLAVAETGSLTAAAVRLGMSQPSIGRHIAELERLLD
                     MQLFRRGPRGQELNERGLDLLNEVRRMGDAADALSRIALGHSQSLTGTVRVTASEVIG
                     ALVLPRLVAELRQQEPLIEIEIVASNSLGNLLKRDADIAIRMTRPQQLDLVIRHIGDI
                     PLVPCASSDYFARAGKPQRLEDLAAHELIGYDRSDGIIAGLARAGIKINRSSFKVRSD
                     NHLVLWEALRAGAGISFAQAPLVAGDPDLETCLEDMELPRLETYLTMHSDLRHSPRIR
                     YVADYLFKAMRNYASAG"
     gene            191475..192677
                     /locus_tag="HPDFL43_18957"
     CDS             191475..192677
                     /locus_tag="HPDFL43_18957"
                     /note="COG0399 Predicted pyridoxal phosphate-dependent
                     enzyme apparently involved in regulation of cell wall
                     biogenesis"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase, DegT/DnrJ/EryC1/StrS family
                     protein"
                     /protein_id="ZP_02164609.1"
                     /db_xref="GI:163757520"
                     /translation="MQPFTGSFTQQEALDDEAILAATEVLRSGRLHRYNTVADELSQA
                     SQLEQAFAAYQGSRYCLACASGGYAMAIALRAAGLQQGEAVLTNGFTLAPVPGAITAA
                     GGKPLLVEITEDMVIDLADLERKALESQARFLLLSNMRGHLADMDHLSEIVRKHGLIL
                     IEDCAHTMGAAWNGIKSGNFGLAGCFSTQTYKHLNSGEGGLLTSDDPEFMARAIILSG
                     SYMLYERHGAAPPPQVFEQVRLETPNMSGRMDNLRAAILLPQLARLDESIERWNQRYR
                     EVEQGLAGVYGLLLRHRPDQESFVGSSIQFRLPGIDAAAARTFVADAKALGVELKWFG
                     NDDPVGFTSNHHSWRYVEAQPLPGTDRVLAGLFDMRLPLTFSLEDCRHVAAIIAHCAA
                     PWAMAQAS"
     gene            192807..194582
                     /locus_tag="HPDFL43_18962"
     CDS             192807..194582
                     /locus_tag="HPDFL43_18962"
                     /note="COG0028 Thiamine pyrophosphate-requiring enzymes
                     [acetolactate synthase, pyruvate dehydrogenase
                     (cytochrome), glyoxylate carboligase, phosphonopyruvate
                     decarboxylase]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164610.1"
                     /db_xref="GI:163757521"
                     /translation="MTTEEAFVKVLQMHGIEHAFGIIGSAMMPVSDLFPSAGIAFWDC
                     AHETNAGLMCDGFIRSTGKMAMAIAQNGPGVTGFVTPVKTAYWNHTPMLLITPQAANK
                     TIGQGGFQEMEQMRLFADCVCYQEEVRDASRIPEVLNRVIMKAWRGSAPAQMNIPRDM
                     WTQVIDVELPQVVRFERPAGGDQAISDAAALLSKAQFPVILSGAGVVLSGAIPDLVKL
                     AERLDAPVCSNYQHNDSFPGSHRLAVGPLGYNGSKAAMELIAKADVVLALGTRLNPFS
                     TLPGYGIDYWPKDAEVIQVDINADRIGLTKKVTVGIEGDATKVARAILAQLSDDAGDA
                     GREDRRNLVSLTKSRWAQELSSLDHEEDDPGTSWNEESRKRDADLMSPRQAWRAIQSS
                     LPKDAIISSDIGNNCAIGNAYPSFEQGRKYLAPGLFGPCGYGFPSILGAKIGQPDVPV
                     IGFSGDGAFGISMNEMTACGRDEWPAITMVIFRNYQWGAEKRNTTLWYDNNFVGTELD
                     RDTSYAAIAEACGAKGVVVNSQQSLTEELAKAVERQMKDGETTFIEVILNQELGEPFR
                     RDAMKKPVVVAGISRDDMRPQQGAV"
     gene            complement(194655..196157)
                     /locus_tag="HPDFL43_18967"
     CDS             complement(194655..196157)
                     /locus_tag="HPDFL43_18967"
                     /note="COG1167 Transcriptional regulators containing a
                     DNA-binding HTH domain and an aminotransferase domain
                     (MocR family) and their eukaryotic orthologs"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, gntR family,
                     putative"
                     /protein_id="ZP_02164611.1"
                     /db_xref="GI:163757522"
                     /translation="MAGYAGQNRLDVCMSIPIDTFFLDPKFEGTLQQKIQRMISEGVL
                     SGRFNPGSKLPSSRKLAAHLGISRITVTLAYSELVSDDYLIAKGRSGYYVSPTAPQRT
                     RFESLTGVTSDSVDWGRAIAQRYSGQVLVEKPVDWRSYPYPFIYGQADEKIFDHSNWR
                     QCALQALGKREFETVTADSYERDDPELVKYIALNTLPRRGIQAKPEQILITMGGQNAL
                     WMAAKVLLNQRRTAVMENPGYPGLRAALNLARCNVVNVPVDHAGMCLDSVPPETDVVF
                     TTPSHHCPTSVTMPLERRQALLEMAARNDFIVVEDDYEFEMSFLNPPAPALKSLDEEG
                     RVIYVGSFSKSLFPGLRLGYIVGSETFIREARALRMVVVRHPPGHLQRTVANFLSLGH
                     FDALVARMGQTYRRRRDVMQEAIDRRGLQIAGADVSGGSSFWMKTPDRIDARALAEAV
                     KQRGVLIEPGHFFFANPEDGNRFYRIAYSSIDSARIPGGIDIIADTIASL"
     gene            complement(196247..197641)
                     /locus_tag="HPDFL43_18972"
     CDS             complement(196247..197641)
                     /locus_tag="HPDFL43_18972"
                     /note="COG0161 Adenosylmethionine-8-amino-7-oxononanoate
                     aminotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="probable
                     adenosylmethionine-8-amino-7-oxononanoate
                     aminotransferase"
                     /protein_id="ZP_02164612.1"
                     /db_xref="GI:163757523"
                     /translation="MNMPIQSGIQPNDIQAVIDADKNHVWHHLIQHKPFETVDPRIMV
                     EGRGMRVWDATGKEHLDAVSGGVWTVNVGYGRESIANAVRDQLVKMNYFANSAGSIPG
                     ALFAQKLIEKMPGMSRVYYSNSGSEANEKAFKMIRQISHRHHGGRKYKILYRDRDYHG
                     TTLATLSAGGQPQRAEQYGPMAPGFVKVPHCLEYRNQFPDAESYGEAAANAIEEVILR
                     EGPDTVGGLCLEPITAGGGVITPPEGYWPRVQEICRKYDILLHIDEVVCGVGRTGEWF
                     GYQHYGVKPDFVTMAKGVASGYAAISCTVTTEAVFEQFKDDPSDPMSYFRDISTFGGC
                     AAGPAAALENMRIIEDENLIENTQAMGARMLDNLRALQDKHAVIGDVRGKGLFLGAEL
                     VSDRTSREPAEEKKVQAVVADCMGQGIIIGATNRSLPGFNNTLCFSPALIATADDIDR
                     ITDSVDQALTRVFG"
     gene            197827..197991
                     /locus_tag="HPDFL43_18977"
     CDS             197827..197991
                     /locus_tag="HPDFL43_18977"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164613.1"
                     /db_xref="GI:163757524"
                     /translation="MAFVLWLIDFELLTPKTKSKIVKENGNSAGRASDDGVHVQSPSG
                     WSGDDKGVSL"
     gene            197988..198980
                     /locus_tag="HPDFL43_18982"
     CDS             197988..198980
                     /locus_tag="HPDFL43_18982"
                     /note="COG4521 ABC-type taurine transport system,
                     periplasmic component"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter, periplasmic
                     taurine-binding protein"
                     /protein_id="ZP_02164614.1"
                     /db_xref="GI:163757525"
                     /translation="MKIASRMSSLLAGIAMVAVASAAKAEEITVGYFLEWPMPFQFAK
                     ATGLYDEALGMKVNWKSFDAGTAMSAAMASGDVQISVSQGVPPFVVATSAGQDLQIAD
                     IAVVYNDNDNCVVKEELEITKENAKELEGKKAGVPIGTAAHYGFLKQMEYFGVDVSTM
                     EVVDMAPPDGAAAFAQGSLDMVCGWGGSLRRMVEHGNVLLTGAEKDEIGISVYDVTSV
                     PASFAAENSDVLAKFLKVTADMNAKWLTDSAEMLPVIAKDAGMSEEDTAATLAGFQFP
                     TVEDQLSDKWLGGATQTFLKGVGDFFKAQGNIPASRDTYDGAVTTDALSSASQM"
     gene            199001..199873
                     /locus_tag="HPDFL43_18987"
     CDS             199001..199873
                     /locus_tag="HPDFL43_18987"
                     /note="COG4525 ABC-type taurine transport system, ATPase
                     component"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter related protein"
                     /protein_id="ZP_02164615.1"
                     /db_xref="GI:163757526"
                     /translation="MSRPIGRDIRPRQFLFRAIGATMGDLVIDKLSMRFDLPDGGSVQ
                     ALQDVSLKLAKGELLSVLGPSGCGKTTLLNIVAGFLAPTDGTVSLNGATVTGPGPERG
                     MVFQQGALFEWMNVRRNISFGPDMAGKPDSETQPVVDHLLRTVGLQDFGNKMIYELSG
                     GMQQRVALARCLANDPDVILMDEPLGALDALTREKMQGLVLKLWKETGKTIILITHSV
                     EEALLLGERLLVMAPRPGRIHKEYRLPFAEMGVGQDLRMVKKDPAFGERREEILGMIW
                     DMEEEIMGRQEEPA"
     gene            199870..201138
                     /locus_tag="HPDFL43_18992"
     CDS             199870..201138
                     /locus_tag="HPDFL43_18992"
                     /note="COG0600 ABC-type nitrate/sulfonate/bicarbonate
                     transport system, permease component"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter, permease protein"
                     /protein_id="ZP_02164616.1"
                     /db_xref="GI:163757527"
                     /translation="MIVLFIYVALFALAYIAYRAWDRSQEHRHDFVSLKTVTFGDESA
                     VSANRFASVVSIVALFAIWGAFTGSVITPLHVPGPFVGDTSFTYTARNAQGETDDGVV
                     AVRVHKVGEEVPLPEVATSSDGFAVDDAVKIGAWRSSLSRPFDNDIGGEEDGYAVIAI
                     DGQPIAPGDTVRFSDGEITMTAKGSLSVKPDKGWQMEPIWLPSPEAVVYRLGEIATEG
                     YKNVSLWEHLGYSLGRVIAGFLLGSIIGIPLGYAMGLSNWFRGWFDPIVEFMRPVPPL
                     ALIPLIIIWFGIGEEGKVILLFLAALWIMTIAARAGVSGVRISKVHAAYSLGASKWQI
                     LRHVILPNSLPEIFTGARVAMGVCWGTVVAAELVAADRGAGMMIVNASKFQLTDIVIL
                     GIILIGIIGYGIDILMRMAEKWLVPWKGRG"
     gene            complement(201342..203777)
                     /gene="gyrB"
                     /locus_tag="HPDFL43_18997"
     CDS             complement(201342..203777)
                     /gene="gyrB"
                     /locus_tag="HPDFL43_18997"
                     /note="COG0187 Type IIA topoisomerase (DNA gyrase/topo II,
                     topoisomerase IV), B subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit B"
                     /protein_id="ZP_02164617.1"
                     /db_xref="GI:163757528"
                     /translation="MTDTPETDPTVEAEYGADSIKVLKGLDAVRKRPGMYIGDTDDGS
                     GLHHMVYEVVDNAIDEALAGHADRVTVTLNPDGSVTVTDNGRGIPTDMHQGEGISAAE
                     VIMTQLHAGGKFDQNSYKVSGGLHGVGVSVVNALSVWLKLVVRRKGKIHEIRFTHGVA
                     DAPLQVLGDCGDETGTEVTFMPSSETFTMIDFDFGTLEHRLRELAFLNSGVRILLADR
                     RHSDAKELELYYEGGLEAFVRYLDRSKKPLVNDPVTLIGEKDGITVELAMWWNDSYHE
                     NVLCFTNNIPQRDGGTHMAGFRAALTRQMVSYADVSGMTKKEKVSLTGDDCREGLTAV
                     LSVKVPDPKFSSQTKDKLVSSEVRPVVENLVNSTLSSWLEEHPTEAKTLVGKVIEAAA
                     AREAARKARELTRRKGALDIASLPGKLADCSERDPAKSELFLVEGDSAGGSAKQGRSR
                     ENQAILPLRGKILNVERARFDKMLSSQEIGTLITALGTGIGKDEFNADKLRYHKIIIM
                     TDADVDGAHIRTLLLTFFFRQMPVLIERGHLYIAQPPLYKVSRGKSSQYLKDEKAMEE
                     YLVSSGLEEAALELSTGEVRTGADLKDTITDALRMRMLLESLHSRYDHTVVEQAAIAG
                     ALNPERTTDPASSDDMAAEVARRLDMVSEESERGWTGAATENGGLRFERMVRGVKESV
                     HLDAGLIGSQDARMIDQMNAKLRDVYTEPPVLRRKEGGLQISGPRELLDAVFSVGRKG
                     LALQRYKGLGEMNAEQLWETTLDPNARSLLQVRVNDAVDADSLFSRLMGDEVEPRREF
                     IQDNALSVANLDI"
     gene            complement(203806..204072)
                     /locus_tag="HPDFL43_19002"
     CDS             complement(203806..204072)
                     /locus_tag="HPDFL43_19002"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164618.1"
                     /db_xref="GI:163757529"
                     /translation="MTVRMISNREGGLVRGTGAGGTNGLADASMVIPSEDDHLEGDLF
                     IPIYALKYPQFHGCGDLVFTGQTPIVQHSNCGDSPPCFPDFPPG"
     gene            204071..205408
                     /locus_tag="HPDFL43_19007"
     CDS             204071..205408
                     /locus_tag="HPDFL43_19007"
                     /note="COG2124 Cytochrome P450"
                     /codon_start=1
                     /transl_table=11
                     /product="probable cytochrome p450 protein"
                     /protein_id="ZP_02164619.1"
                     /db_xref="GI:163757530"
                     /translation="MRNPLELWGEPSFRLKWMKTKFFNERTLIANHPGLVRHVLVDNA
                     QNYRMATIRQLILRPILRDGLLTAEGETWKRSRKAMAPVFTPRHARGFAEQMLAQSQA
                     FKDRYVAAVDSNSGTGDVRDIAVDMTELTFDILSATLFSGHVAGSEEEFAGDIERLLS
                     TMGQVDPMDLLKAPRWIPRIRRMFGQKVLDKFRAIVKQTMDDRQKMMRDEPDAVPEDF
                     LTLLIRLHHPAGLTLDEIEDNIITFIGAGHETTARALGWTLYCLANSPADREKVEAEI
                     DEVIAREPDPVKWLDQMPWTRAVFEEAMRLYPPAPSINRAAITDDSWQDEKGETVTIE
                     AGTTVLVMPWTLHRHTLLWDRPEAFIPSRFLPENRGSIDRYQYLPFGVGPRICIGATF
                     ALQEAVIALGALLSEFRFDCVAETKPWPVQKLTTQPEGGLPMRVSRRQGNASR"
     gene            205483..207486
                     /locus_tag="HPDFL43_19012"
     CDS             205483..207486
                     /locus_tag="HPDFL43_19012"
                     /note="COG0145 N-methylhydantoinase A/acetone carboxylase,
                     beta subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164620.1"
                     /db_xref="GI:163757531"
                     /translation="MTLPLFLGIDTGGTYTDAVLYSESEGILASAKALTTRHDLAVGV
                     AGAVETVLSDLSGAAARISLVSLSTTLATNALVEGQGGRAALVMIGFSPEDLGRDGLA
                     DALGNDPVIQLPGGHDVHGRETPLDLTLLEERLASLPDEVSAVAIAGYFAVRNPAHEI
                     AARDLIRARTALPVTCSHDLSSKLGGPRRALTTLLNARLISMVARLIDATSGYLEKRG
                     IDAPLMVVRGDGALISAQEALLRPIETILSGPAASLVGARHLTGLSDAVVSDIGGTTT
                     DVAVLENGRPRLDTEGATVGRYRTMVEAVAMHTFGLGGDSEVRTEEAGLEAGLILGPR
                     RLMPLSLAGQLWPDTVVPALERQLRASFPGRLDGRFALRTGLPDALAAGLAAQESALY
                     SRIEAEPQPLETVLTGTSQRATLDRLVARGLVMIAGFTPSDAMHVLGRQDQWNAEAAR
                     LGAELFTRRKAGSGKALAQSPAELANMVSERLTRQSAEAILTALFADQGVHGIDPNRS
                     VLIDRALNRAPGFVRFGLGLDRPLVALGASAPVHYPAIAAMLDAESFVPVHAGVANAV
                     GAVVGQVRETVIAFVTEPEEGRFAVNGAGDARIVKNLDEAFALARELARNQACDAAIR
                     SGAENPVIESFEHIDMPLIEGLEKLVEARFTAIASGRPRIAGK"
     gene            207622..209778
                     /locus_tag="HPDFL43_19017"
     CDS             207622..209778
                     /locus_tag="HPDFL43_19017"
                     /EC_number="2.3.3.9"
                     /note="COG2225 Malate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase"
                     /protein_id="ZP_02164621.1"
                     /db_xref="GI:163757532"
                     /translation="MNRIETNGLKISADLHEFIVNEALPGTGVEAARFFEALGTAIAE
                     LAPKNRALLAKRDELQEKIDAWHREHGAPVDLDVYKDFLTSIGYLLPEGGEVRVSTEN
                     VDPEIASIAGPQLVVPVMNARFALNAANARWGSLYDALYGTDALGDLPQAGGYDQARG
                     ARVIAWSKSFLDDSVPLGNAKWADVTGFDFESGELKIKTAAGETALADPAQYTGFKRE
                     SDNAYRLYFLKNGLHAVVFVDPGSVIGKTDPAGIGDISLESAVTAIMDCEDSIAAVDA
                     EDKVLVYRNWLGLMKGDLEEEVHKGGKSFVRRLNGDIDFTARDGKPATLKGRSLMLIR
                     NVGHLMTNPAIHDADGNEVPEGIMDAFMTGLIALHDIGPNGRRANSATGSMYVVKPKM
                     HGPEEVAFAVEIFGRVEAALGMKPNTIKMGIMDEERRTTVNLKECIRAASQRVVFINT
                     GFLDRTGDEIHTSMEAGPMIRKGDMKQAAWIAAYENWNVDIGLECGLAGHAQIGKGMW
                     AMPDMMEAMLEQKIGHPKAGANTAWVPSPTAATLHATHYHKVNVADVQAGLRSRKRAS
                     LDDILSIPVARKPNWTQEEIQLEIDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLME
                     DRATLRISAQHMANWMHHGIVSREQIVETMKRMAEVVDGQNVGDPAYRPMAADFDGSV
                     AFQAALELVLAGREQPNGYTEPVLHRRRLEFKANIA"
     gene            complement(209863..210516)
                     /locus_tag="HPDFL43_19022"
     CDS             complement(209863..210516)
                     /locus_tag="HPDFL43_19022"
                     /note="COG1376 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164622.1"
                     /db_xref="GI:163757533"
                     /translation="MTPRFLLTLVGMIAALALAGCSSSQDGVSGTTTQIFTSEYGSVK
                     DAGYRIPAVPISKVKDRYHRQIVSYRTLEKPGTIIVDTPNRYLYFVLPGRKAVRYGIG
                     VGKAGFAWEGEAYIAWKQAWPKWTPPKEMIERKPELARYGKDGMKPGLSNPLGARALY
                     LFNEDGEDTLFRLHGTPEWNSIGTAASSGCIRLMNQDIIDLYDRVRPGRGAKVVVKQ"
     gene            210723..211199
                     /locus_tag="HPDFL43_19027"
     CDS             210723..211199
                     /locus_tag="HPDFL43_19027"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164623.1"
                     /db_xref="GI:163757534"
                     /translation="MPIVSPHNDNPLIDGRQSDRAMMVRRGVQRFFSDLRLSMVPEIA
                     LASGRRADLMALNDKGEIWIVEIKSSVEDFRSDRKWPDYRAHCDRLFFATHSGVPPEL
                     FPEDCGLIVSDGWSADLLREAPEHRLAAASRKAVLLRFARAAADRLLQAELSANPI"
     gene            complement(211250..211819)
                     /locus_tag="HPDFL43_19032"
     CDS             complement(211250..211819)
                     /locus_tag="HPDFL43_19032"
                     /note="COG4567 Response regulator consisting of a
                     CheY-like receiver domain and a Fis-type HTH domain"
                     /codon_start=1
                     /transl_table=11
                     /product="putative two-component response regulator
                     transcriptional regulatory protein"
                     /protein_id="ZP_02164624.1"
                     /db_xref="GI:163757535"
                     /translation="MTSDTANLTETQSIGPDASLLLVDDDGPFLRRLARAMEARGFAV
                     DIAETVAEGLAKARHHPPKYAVVDMRLQDGNGLDVIEAIRERRDDTRIIVLTGYGNIA
                     TAVTAVKLGAIDYLAKPADADEVFAALTRKPGERAEVPENPMSADRVRWEHIQRVYEM
                     CERNVSETARRLNMHRRTLQRILAKRAPR"
     gene            complement(211881..213221)
                     /locus_tag="HPDFL43_19037"
     CDS             complement(211881..213221)
                     /locus_tag="HPDFL43_19037"
                     /note="COG0642 Signal transduction histidine kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component, sensor histidine protein kinase"
                     /protein_id="ZP_02164625.1"
                     /db_xref="GI:163757536"
                     /translation="MTVFPPFLEDQSLRHRLRLQTLTRLRWLAVAGQSLAVVIIAHGY
                     GFEFPEALCFALIACSAWLNVFLSVRFPAAHRLPPLGAMAVLSFDVLQLSGLLFMTGG
                     LANPFSVLLCVPVIISSASQPVRHTVGLGALSVAAVTLLAFYSLPLPWYPDSDFEVPF
                     LLIVGAWIAIVSTTVFAAVYAYQVSAEATQLADALVATELVLQREQHLSALDGLAAAA
                     AHELGTPLATISVVAREMEKALASDPRFADDIMLLRSQSERCRDILRRLTTLSTQDEV
                     HMARLPLGSLIEEIIAPHREFGIAIEVVSGDSDLKEPVGRRNPGIIFGLGNLIENAVD
                     FADSQVTVTVSHDADRVSITIDDDGPGFAPDVLTQIGVPFMNRRSRLDREKAGGLGLG
                     LFIAKTLLERSGATLSFANRPLPATGAHVQVRWPREKMDVLGADSSRIAPTGTG"
     gene            complement(213265..215730)
                     /locus_tag="HPDFL43_19042"
     CDS             complement(213265..215730)
                     /locus_tag="HPDFL43_19042"
                     /note="COG1643 HrpA-like helicases"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase protein"
                     /protein_id="ZP_02164626.1"
                     /db_xref="GI:163757537"
                     /translation="MNGIAARFASLPVCDVLPALCEALTHHSRAVLAAPPGAGKTTLA
                     PLVFREQGWLEGKIILIEPRRLAARAAARRMAAMLGEEVGATVGYRMRLDTRVSRNTR
                     IEVVTEGVFTRMALESPDLEGIGCVIFDEFHERALEADFGLALALDIQSGLREDLRIV
                     VMSATLDTTRVATLLENCPVIESQGRSHPVEIRHLDRTAGERIELSMTRAIETLHRAE
                     SGSILAFLPGQGEIKRVEQALESRLGPETDVQPLYGGLGSGEQDAAIRPAPKGRRKVV
                     LATTVAESSITIDGVRIVIDSGLVRQPVYEPSTGITRLETVRASRASADQRAGRAGRT
                     EPGIAVRLWREEQGKALPAFATPQILASDLASMVLDCIAWGVSDPRELRFIDGPPGPA
                     IEEARSLLTGLGAIDAKGVLTPRGQQMRALALPPRLAAMVVAGREQGVGQAAAELAVL
                     LTEQGLGGTATDLDVRWQRFRSDRSPRASAARSLAGRLAGAGRKAERSEMPGAAGLLA
                     TAFPDRVAKQRGGRGQFVLANGRGAVIDETDRLAGAGYIVVADLSGKAQAARVLAAAE
                     LAGSELDELLADRAETKQECVFDEASGAVRARRVTRLGAITLAEAPLPKPETSEAMAA
                     LCAGIRKLGLRCLPFSAAGQQLRDRIGFLHQSLGDPWPDVSDAALLDSLETWFAPFQP
                     GITALKTIDRDGLHQGLLSLCAPGAQTEINRLAPTHYEAPTGSRLPVRYGEEGPVVAI
                     RVQELFGLSGHPSIGGGRLPLTLELLSPAQRPIQTTRDLPGFWKGSWADVRSEMRGRY
                     PRHPWPENPGEAEPTRRAKPRTR"
     gene            complement(215727..216386)
                     /locus_tag="HPDFL43_19047"
     CDS             complement(215727..216386)
                     /locus_tag="HPDFL43_19047"
                     /note="COG4136 ABC-type uncharacterized transport system,
                     ATPase component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative atp-binding abc transporter protein"
                     /protein_id="ZP_02164627.1"
                     /db_xref="GI:163757538"
                     /translation="MMNSMTDNQGLVLDHVRIALEGRELVSISARIRCGETLTVMGPS
                     GSGKSTLLAYLGGFLDPAFTASGGVYVDGIDLIALEAEKRHAGILFQDPLLFPHLSVA
                     DNIAIAIPDTVRGRKQRRAMAEAALEDAGLAGFGNSDPDTLSGGQKARVALQRVLLSQ
                     PRLLLLDEPFSKLDAHLRDQTRQMVFSKARCAGLPVVLVTHDEADAGAAGGEVHRVGQ
                     S"
     gene            complement(216386..218077)
                     /locus_tag="HPDFL43_19052"
     CDS             complement(216386..218077)
                     /locus_tag="HPDFL43_19052"
                     /note="COG4135 ABC-type uncharacterized transport system,
                     permease component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative permease ABC transporter protein"
                     /protein_id="ZP_02164628.1"
                     /db_xref="GI:163757539"
                     /translation="MKVGGVRLARVAPPLTLAVLLGPLVFGLAGTALPAFGYLPELGG
                     EHFTTEHFGVLGAQPGIARSALLSILIGLVTTLISLGTVAAFVASDLGTTTFSRVRRL
                     ISPLLSVPHAAAAFGLAFMIAPSGMIMRLISPWATGLDRPPDLLIVNDPMALSMMAGL
                     IVKEIPFLFLVTLAALPQTRHSETMRLGRSLGYGRIASFTFLLWPPLYRQIRLAVFAV
                     VAYATSVVDVALILGPHLPPTLPVRLIDWMNDPNLETRFLASAGAVMQLSVTLAALLI
                     WVVIERIGALAVCLVRDRGARMRRDLIVRILARLMMSSSALVVFGGIAILALWSVSGL
                     WQFPDALPANFSMRSWMQAMPRMSGPLATTLAVAGLSTLIALVLTILCLEREYETGRG
                     RDALLLIYLPLIVPQISFMFGLQVLSIWLGVDASFGALVLAHLVFVLPYVFLSLSDPW
                     RAHDRRHDQIAAGLGISRGRALLHIRLPMLTRAILTAAAVGFSVSVGQYLPTLLIGAG
                     RLTTVTTEAVALAAGGNRRVIGVYAFMQTLLPFIAFAIAMGLPGLIFRNRRGLRV"
     gene            complement(218224..219456)
                     /locus_tag="HPDFL43_19057"
     CDS             complement(218224..219456)
                     /locus_tag="HPDFL43_19057"
                     /note="COG4134 ABC-type uncharacterized transport system,
                     periplasmic component"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164629.1"
                     /db_xref="GI:163757540"
                     /translation="MIKISTFFAGVLTAAMALSQPALAADPDPRNWDAVLEEARGQTV
                     YFNAWGGSENINSYIDWAGSTLKERYGVNVVHVKLDDTANAVAKVLAEKATGKNEGGS
                     VDLIWINGENFASMKRQELLMSPDWTTGLPNWAYVDHENKPTILTDFTIPTDGLESPW
                     GGAKLVFFHDTARTPADSVPQSSADLLKWAQENPGRFSYPQPPDFIGSSFLKQVLSEV
                     IVDKSKLSKPVDDASFAEDAAPLFAYLDALHPNLWRSGKAYPQNYPDMKQKLADGELD
                     IIFAFNPSEASAGIAAGELPDTVRSFTYPAGTLGNTHFVAIPYNAAAKAGALVLADFL
                     ISPEAQARKQDPAIWGDPTVLSMDKLSDEDRAAFDALDLGIATLKPDELGPALDEPHP
                     DWMERIEGEWVRRYGAAN"
     gene            complement(219667..222609)
                     /locus_tag="HPDFL43_19062"
     CDS             complement(219667..222609)
                     /locus_tag="HPDFL43_19062"
                     /note="COG0258 5'-3' exonuclease (including N-terminal
                     domain of PolI)"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="ZP_02164630.1"
                     /db_xref="GI:163757541"
                     /translation="MKKGDHLFLVDGSGYIFRAYHALPPLTRKSDGLPVGAVSGFCNM
                     LWKLVSEARDTSVGVTPTHFAVIFDHSSKTFRNELYPEYKANRSAPPEDLVPQFAVIR
                     EATRAFDLPCIEMEGFEADDLIATYARLAREAGADVTVISSDKDLMQLVGPQVSMYDS
                     MKDRQIGVPEVIEKWGVPPEKMIDLQALTGDSVDNVPGIPGIGPKTAAQLIEQFGDLD
                     TLLERAGEIKQNKRRENIVEFADKARISRELVRLRDDVEVSEKLGELVLNPLNGPKLV
                     AFLKGMEFTSLTRRVADATDTDASAVDAADVAVDAAAEMRGPDLDPGDAANAAVTATG
                     QNDDTPQGLAKRRAAEAGSAKIDTTAYETLSDIEQLKAWCAMARETGVVAFDTETTSL
                     DAMQAELVGFSLAVPEAAPDTGELKVRACYAPLAHSNGVGDLLGGGGLQPGQMPVRAA
                     LDELKALLEEPAVLKIGQNLKYDMLVMAQHNIEIKSFDDTMLLSYVLDAGQGGHGMDA
                     LSERWLGHKTIGYKDVTGSGKSAIPFAQVAIDKATAYAAEDAEVTLRLWHALKVRLVS
                     EGMTSVYERLERPLAPVLMRMEQRGIRVDRQILSRLSGELAQGAAALEAEIQELAGEN
                     FNVGSPKQLGEILFDKMSLPGGSKTKTGQWSTSAQALEDLAAAGHELPRKIVDWRQLT
                     KLKSTYTDALPGFINPETKRVHTSFAMAATTTGRLSSSDPNIQNIPVRTAEGRKIRTA
                     FVAEPGNVLISADYSQIELRVLAHVANIPQLTQAFADGVDIHAMTASEMFGVPIEGMP
                     SEVRRRAKAINFGIIYGISAFGLANQLSIERSEAGDYIRKYFERFPGIKDYMDATKAE
                     AKENGYVTTIFGRRAHYPEIRSSNPQVRAFNERAAINAPIQGSAADIIRRAMVRMEPA
                     LEAAGMQARMLLQVHDELIFETAEADADKIIPVIVEVMENAAMPAIDMAVPLQVDARA
                     AKNWDQAH"
     gene            222985..224376
                     /locus_tag="HPDFL43_19067"
     CDS             222985..224376
                     /locus_tag="HPDFL43_19067"
                     /note="COG0624 Acetylornithine
                     deacetylase/Succinyl-diaminopimelate desuccinylase and
                     related deacylases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative peptidase"
                     /protein_id="ZP_02164631.1"
                     /db_xref="GI:163757542"
                     /translation="MTDLNAVLSAADANLDASLERLFGLLRIQSISTDPAYAPECRRA
                     GQWLVDELNGLGFDASLRDTPGHPMVVAHHDGATPDAPHYLFYGHYDVQPVDPLDLWT
                     DPPFEPAIKQIEPGRKAITGRGAADDKGQLMTFVEACRAWKAVSGALPCRITILFEGE
                     EESGSPSLRPFLKANAEELKAECALVCDTGMWDAKTPAISVGLRGLVGEQVTIHAADR
                     DLHSGLFGGAAANPLHILSKILADLHGETGRVTLEGFYDGVTDTPAQILASWESLGKT
                     AESFLGEVGLSVPAGETGRSVLEQTWARPTAEVNGMWGGYTGEGFKTVIAAEASAKVS
                     FRLVGKQDPDQIRAAFRAHVEARLPADCSASFAPHGGSPAIQLPFDSPVVTKARNALT
                     DEWPNPAVMIGMGGSIPIVGDFQNILGLQSMLCGFGLTDDRIHSPNEKYDLTSFAGGI
                     RSWVRILDALSRK"
     gene            224533..226791
                     /locus_tag="HPDFL43_19072"
     CDS             224533..226791
                     /locus_tag="HPDFL43_19072"
                     /note="COG0744 Membrane carboxypeptidase
                     (penicillin-binding protein)"
                     /codon_start=1
                     /transl_table=11
                     /product="putative penicillin-binding protein"
                     /protein_id="ZP_02164632.1"
                     /db_xref="GI:163757543"
                     /translation="MLRAVATCCANDPGRDPPETEPGPFMPRKITPQSRIEPSFEKTR
                     SKSAKRTVADERVAGKSAPAKRRKKPASKARKPKARNGRSRLGRAFRSLIYWSFVLAI
                     WGGIAIAGVVAYYGARMPSAATWSIPDRPPNVKIVSVRGEVMANRGATGGEAVLLGDM
                     SPYIPQAVIAIEDRRFYSHFGVDPIGLARAMVANVSAGRMVQGGSTLTQQLAKNLFLS
                     PERTIERKVQEVLLSLWLEHKFAKDQILEMYLNRVFFGSGAYGVEAASRRYFRKPARD
                     VTLAEAALLAGLLKAPSRLSPARNPKGAEERAQVVLAAMREHGVVSDREIATALTSPQ
                     IRAKSYWTGSENYVADMVMKRLPDLVGPVTEDLVVDTTIDFHLQREAEKALRASLEAN
                     GAKLAVSQGALVSVDGTGAVRALIGGREYATSQFDRATEAKRQPGSAFKPFVYAAALE
                     QGRTPLSVRNDAPVRIGKWTPENYDGKYRGAVTLSDALTFSLNTVAAQLAMEVGPKTV
                     VQTARRLGIEADMKANASIALGTSEVTLMELTAAYAPFMNGGYKATPHVIRRVSTQDG
                     KVLYENTYDNPPRVIDPLVAAMMNQMLVRVVSEGTGKKAGLDGWMAAGKTGTSQSFRD
                     ALFVGYTANLATGVWFGNDNGAPMKKVTGGALPAQTWKTFMQAAHKGLPAVRLPLAGP
                     VPPVSIGGSSIAEDDPVAGLMRDLIPIPLSRDSTGATGDSPLVPPADVGVSPQPGGNA
                     PRTTLLDILMGN"
     gene            227109..229028
                     /gene="dnaK"
                     /locus_tag="HPDFL43_19077"
     CDS             227109..229028
                     /gene="dnaK"
                     /locus_tag="HPDFL43_19077"
                     /note="COG0443 Molecular chaperone"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="ZP_02164633.1"
                     /db_xref="GI:163757544"
                     /translation="MAKVIGIDLGTTNSCVAVMDGKDARVIENAEGSRTTPSMVAFSE
                     DGERLVGQPAKRQAVTNPENTLFAVKRLIGRRYEDKAVTKDKELVPFKISRGDNGDAW
                     VEANGESYSPAQISAMILQKMKETAESYLGESVDKAVITVPAYFNDAQRQATKDAGKI
                     AGLEVLRIINEPTAAALAYGLDKTEGKTIAVYDLGGGTFDVSILEIGDGVFEVKSTNG
                     DTFLGGEDFDMRLVGYLADEFKKDQGIDLKKDKLALQRLKEAAEKAKIELSSASQTEI
                     NLPFITADASGPKHLTLKLTRSKFESLVDDFVQRTIAPCKAALKDAGLQAAEIDEVVL
                     VGGMTRMPKIQEVVKQFFGKDPHKGVNPDEVVAMGAAIQAGVLQGDVKDVLLLDVTPL
                     SLGIETLGGVFTRLIDRNTTIPTKKSQVFSTAEDNQNAVTIRVFQGEREMAADNKMLG
                     QFDLVGIPPAPRGVPQIEVTFDIDANGIVNVSAKDKGTGKEHQIRIQASGGLSDSDIE
                     AMIKEAETNAEADKKRRAVVEAKNQGESLVHSSEQSLKDYGDKVSEEDRTAIANAIAA
                     LKAAVEAEEPDAEDIQAKSQTLMEVSMKLGQAMYEQNQAEAEAEDGAEGGSDDKVVDA
                     DFEEVKDDDDQKKSA"
     gene            229166..230284
                     /locus_tag="HPDFL43_19082"
     CDS             229166..230284
                     /locus_tag="HPDFL43_19082"
                     /note="COG1835 Predicted acyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164634.1"
                     /db_xref="GI:163757545"
                     /translation="MIGEAGGMKQNYRLFGAWRLLAALLVMAYHFAHHAPNPDPITDW
                     FEHMLPLLDMFFIMSGFLIFEHYGAMRNDRDHYVRFLIKRLARLYPLHLATLSVFVLF
                     AIAIHAGLLSSQGADSRYNLMALPSNLLLLQAWGVNSELTFNYVSWSLSGEWFAYLLF
                     PLVLFAFSSGRVWGLALLLAFFVAILEFLDRGATEKYDFWFNTKLWAAYRIAADFVFG
                     AMLCAIARQLDVPRHSQLLAWSILGLVFVAMFSDANIYLILGLFGVAIVLAALADKTG
                     GDETAWLNPAASVMAVSFGIYLWHPVIELFAYSLIWNRILGIDDPLLFWLFMPIPALA
                     TIMVALYSARYLERPAGKWIERSLTKAWSERVLERKTA"
     gene            230469..231614
                     /locus_tag="HPDFL43_19087"
     CDS             230469..231614
                     /locus_tag="HPDFL43_19087"
                     /note="COG0484 DnaJ-class molecular chaperone with
                     C-terminal Zn finger domain"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone, DnaJ family protein"
                     /protein_id="ZP_02164635.1"
                     /db_xref="GI:163757546"
                     /translation="MAKPDFYETLGVARGADEKELKSAFRKLAMKYHPDKNPDDADAE
                     RKFKEINEAYEFLKDPQKRAAYDRFGHAAFEQGGPGGMGGGGFGAGGGGGFSDIFEDI
                     FGEMMGGGRGRRSSGGRERGADLRYNMEISLEEAYAGKTAQIRVPTSITCDTCTGSGA
                     KPGTQPSTCSTCGGSGRVRAAQGFFSIERTCPTCHGRGQTITDPCTKCSGQGRVTEER
                     SLSVNIPAGIEDGTRIRLAGEGEAGMRGGPTGDLYIFLSVRPHAVFQREGADLFCTVP
                     ISMTTAALGGKFDITTMDGARSRVTVPEGTQPGKELRLRGKGMPVLRSAQFGDLYIRI
                     TIETPQKLSKRQRELLEEFQELSSKENSPESAGFFSRMKGFFDTLTD"
     gene            231720..232310
                     /locus_tag="HPDFL43_19092"
     CDS             231720..232310
                     /locus_tag="HPDFL43_19092"
                     /note="COG3963 Phospholipid N-methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="probable phosphatidylethanolamine
                     N-methyltransferase/phosphatidyl-N-methylethanolamine"
                     /protein_id="ZP_02164636.1"
                     /db_xref="GI:163757547"
                     /translation="MNFPRRFAEHFDEEIRFFRTWMNGPRNTGAILPTSTIAARSMAS
                     LVEPASGLPVLELGPGTGVITRAILDRGVEPSNLMSVEFCAEFHARLMLDLPRVNFIH
                     GNAFDLDTTLGENRKLEFDCVISGIPLLNFPVSDRLMLLEDLLDRLPAGRPVVQFSYG
                     LASPVPAQSGSFEVIHHDFVMRNVPPARIWLYRRGA"
     gene            232463..233044
                     /locus_tag="HPDFL43_19097"
     CDS             232463..233044
                     /locus_tag="HPDFL43_19097"
                     /note="COG0431 Predicted flavoprotein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164637.1"
                     /db_xref="GI:163757548"
                     /translation="MTSRILVLPGSNRSGSFNAALAAAASVELARQGADVTRISLIDY
                     PLPLVDEDLKNESGVPENAMKLGRLIAAHDGVFLCCPEYNSSIPPLLKNMIDWVSMIS
                     KDGDKPLKPWAGRYVALGSASNGKFAGIRGLYHVRSVMMNVGAQVITQQCSVGGAASA
                     FDESGSLIDERTNTMLVGACRSLITHCALASTA"
     gene            233131..233871
                     /locus_tag="HPDFL43_19102"
     CDS             233131..233871
                     /locus_tag="HPDFL43_19102"
                     /note="COG0284 Orotidine-5'-phosphate decarboxylase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative orotidine 5'-phosphate decarboxylase"
                     /protein_id="ZP_02164638.1"
                     /db_xref="GI:163757549"
                     /translation="MPDAMLDLNASAPQTADPRLIVGLDVPTVAEAVAKVEQIGDEAV
                     FFKIGYQLAFAGGLSLARDLKASGRKVFLDMKLLDIDNTVAKGVENIVKMGVDMLTLH
                     AYPKAMRAAVEAAKGSDLCLLGVTVLTSMDAADLKEAGYALSPEELVLRRVAQARTAG
                     MGGIVCAATEARAVREVVGPDMAIVTPGIRPAGADHGDQKRVMTPADALMAGATHLVV
                     ARPIVAAEDPAAAARAIRMEMSQYQEKV"
     gene            233874..234167
                     /locus_tag="HPDFL43_19107"
     CDS             233874..234167
                     /locus_tag="HPDFL43_19107"
                     /note="COG5470 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164639.1"
                     /db_xref="GI:163757550"
                     /translation="MAKAYWIARVDVHDAEGYKAYVETAKPAFVEFGAQFLVRGGACD
                     AVEGQGRARNVVIEFPSVEAAKSCYHSETYQKARAIRQKVSEGEIIIVEGYEG"
     gene            234321..235301
                     /locus_tag="HPDFL43_19112"
     CDS             234321..235301
                     /locus_tag="HPDFL43_19112"
                     /note="COG0702 Predicted nucleoside-diphosphate-sugar
                     epimerases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase protein"
                     /protein_id="ZP_02164640.1"
                     /db_xref="GI:163757551"
                     /translation="MSTLNQPKLVTVFGGSGFVGRHVVRALARRGYSIRVAVRRPDLA
                     GHLQPLGGVGQIVAVQANLRNRDSVDRAVRGADHVINCVGILFESGRNKFDSVQAFGA
                     RAVAEAARAQGAGLTHISAIGADPDSDSDYARTKGYAELAVAEVMPDARIMRPSIIFG
                     PEDGFFNKFAGMARLAPALPLVGGGETKFQPVYVGDVAEAVARSVDGTLVPGAIYELG
                     GPRVMTFRQCLEEMLETIHRKRPLVTLPWGVASLMGKITSLIPFIDPPLTADQVKLLK
                     SDNVVSDEAARENRTLAGIGIRQTTVEAILPTYLGRFRPHGQYSGTGSEA"
     gene            235346..236083
                     /locus_tag="HPDFL43_19117"
     CDS             235346..236083
                     /locus_tag="HPDFL43_19117"
                     /note="COG0730 Predicted permeases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164641.1"
                     /db_xref="GI:163757552"
                     /translation="MESWSALALIFASFFTSALTASAGIGGGLALLALMGYLVPVAAI
                     IPIHGVVQLGSNVGRSVVLRHHIAWGCLAAFLAGAIPGGWIGGQAVGALPDTVLKAAL
                     GGFILVLTWVSLPRLAAISLPGFTLTGMITTFLTMLFGATGPLNAVVLSKTFPERLGF
                     QATTAAVMSLQHLVKTLAFGLAGFAFAPWAPLIALMVLTGLAGTWVGTNVLRRTPEKR
                     FRLIFRICLTLLALDLFRQGVAGMAHG"
     gene            236242..236388
                     /gene="uppP"
                     /locus_tag="HPDFL43_19122"
     CDS             236242..236388
                     /gene="uppP"
                     /locus_tag="HPDFL43_19122"
                     /EC_number="3.6.1.27"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl pyrophosphate phosphatase"
                     /protein_id="ZP_02164642.1"
                     /db_xref="GI:163757553"
                     /translation="MAKTVVTAFAFAAVLILSAAAFSPGSVAGSKGCAPAYGVDPCTL
                     QVGK"
     gene            complement(236394..237197)
                     /locus_tag="HPDFL43_19127"
     CDS             complement(236394..237197)
                     /locus_tag="HPDFL43_19127"
                     /note="COG1968 Uncharacterized bacitracin resistance
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl pyrophosphate phosphatase"
                     /protein_id="ZP_02164643.1"
                     /db_xref="GI:163757554"
                     /translation="MDGTTLVGAALLGLLEGLTEFIPVSSTAHLLLAGHFLGFNSPGN
                     SFEVLIQLGAILAILSVYFARLWKLAMDLPTSAEARRFVGAILLAFLPAAVIGVMAHG
                     FIKTVLFESTALICWVLIGGGIVLLIIDRMPLRPKYTNVMDYPLSLAFKIGLVQCLAM
                     IPGTSRSGATIAGALLLGADKRSAAEFSFFLAMPTMAGAFAYDLYKNYDKLGMDDVTA
                     IIIGFVMAFIAGVIVVRSLLDFVSKHGFAPFAWWRIAVGTLGLIGLWLF"
     gene            237388..238080
                     /locus_tag="HPDFL43_19132"
     CDS             237388..238080
                     /locus_tag="HPDFL43_19132"
                     /note="COG0625 Glutathione S-transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glutathione s-transferase protein"
                     /protein_id="ZP_02164644.1"
                     /db_xref="GI:163757555"
                     /translation="MPVLYHHTVSSASRFIRLCFGEVDYAADLVEELPWEKRPEFIKI
                     NPAGTLPVCVCDNDYALCGPHIIAEWLDESFGVFKRDRRLLAEDPFQRAETRRLMEWF
                     LIKFEQDVVRPLVRERIFKVQLSAKDGGGSPDPKMLRAGRANIRQHMKYLSWLAGSRA
                     WLAGDRLSYADLAAAAALSVMDYLGEIDWNESPQAKDWYQRVKSRPSFRPLLGDRVRN
                     IPPVSHYADLDF"
     gene            238085..239296
                     /locus_tag="HPDFL43_19137"
     CDS             238085..239296
                     /locus_tag="HPDFL43_19137"
                     /note="COG1600 Uncharacterized Fe-S protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164645.1"
                     /db_xref="GI:163757556"
                     /translation="MASDGSPAQDSEGRSARTDAADHLKSFLKKEAAALGFSDLAIAP
                     SDIGAEASDRLARFVELGRHGSMEWLADTRDRRANPKSLWPEVRSVIMLAMNYGPATS
                     PLEGLAQKSRASISVYARNRDYHDIIKGRLKQLAGKFAARAGGDVKVFVDTAPVMEKP
                     LAEAAGLGWIGKHTNLVSRSHGSWLFLGSIFTTVELMPDVAETDHCGSCRACLSACPT
                     DAFPAPYQIDARRCISYLTIENKGPIPHEFRAPMGNRIYGCDDCLAVCPWNKYAQSAS
                     EMKLIAREDLQSPRLAEFLALDDAGFRAFFSGSPIKRIGRNRFLRNVLVAAGNSGDQT
                     LVPACETLLSDPSPLVRGASVWALSQLTLPTRMRELAQSRIGVQDGVVLGETDPEVRA
                     EWDLALNRPNA"
     gene            239312..240184
                     /locus_tag="HPDFL43_19142"
     CDS             239312..240184
                     /locus_tag="HPDFL43_19142"
                     /note="COG0451 Nucleoside-diphosphate-sugar epimerases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164646.1"
                     /db_xref="GI:163757557"
                     /translation="MRLMIFGAGFSGLAIARALAGDCDFAGGTTRSMERFAKLEAAGL
                     TPLIYQGGAPDGDLRTHMAGITHLVMSIAPDAEGDPLLAAFADGLKNHLPALEWAGYL
                     STVGVYGDHGGDWVDEETICKPVSKRSIARVEAEQGWQELALAADVPLAVLRLSGIYG
                     PGRNALKTLDAGKARRLIKPGQVFNRIHVADIGGATTLLARNNLGGVFNVTDDMPAPP
                     QDVVAHAADLMGVAPPPETDFETADLTPMARSFYGENKRVANSRIKAAGYRFTYPDYM
                     EGLGALWRDGGWKG"
     gene            240248..240649
                     /locus_tag="HPDFL43_19147"
     CDS             240248..240649
                     /locus_tag="HPDFL43_19147"
                     /note="COG0797 Lipoproteins"
                     /codon_start=1
                     /transl_table=11
                     /product="rare lipoprotein A"
                     /protein_id="ZP_02164647.1"
                     /db_xref="GI:163757558"
                     /translation="MFEQGVQLIKDQDMTLITSSKPLGALLLATALVALSVAPASAAC
                     GRASWYALTSKTASGERMDPAKFTAAHPRLRFGTMVEVVNPRNGKSVVVRINDRGPFI
                     KGRIIDVSKAAARELGMIRSGVAKVCYKVVS"
     gene            240806..242113
                     /locus_tag="HPDFL43_19152"
     CDS             240806..242113
                     /locus_tag="HPDFL43_19152"
                     /note="COG0624 Acetylornithine
                     deacetylase/Succinyl-diaminopimelate desuccinylase and
                     related deacylases"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase or
                     succinyl-diaminopimelate desuccinylase"
                     /protein_id="ZP_02164648.1"
                     /db_xref="GI:163757559"
                     /translation="MIEGQDIETRQNALAREIAARRDDLVALTQDLIRIPTLNPPGEC
                     YRDICDYLARRLKPSGFEIKLLRAEGTPGDSARYPRWNVVARREGGRVGPCVHFNSHI
                     DVVEAGAGWTFDPFGGTVSDGKIYGRGACDMKGGLAASIIAAEAFIALWPEYPGAIEI
                     SGTADEETGGYGGVAWLAEQGYFSPERVQHVIIPEPLNKDRICLGHRGVMWAQIKTHG
                     RIAHGSMPFLGDCAVRHMGAVISEMESSLFPALAQKHTSMPVVPDGARQSTMNINSLH
                     GGQAEPAPDFTGFPSACVPDEARMVIDRRYLIEEQADEVREEIITLLERVKAERAGFR
                     YDFEELWQVSPTMTSVDAPVVKAVERGIRSALSCEPVHVVSPGTYDQKHIDRIGRLKY
                     CIAYGPGILDLAHQPDEYVGIDDMVDSAKVMAFALDDLLYGRT"
     gene            242158..243648
                     /locus_tag="HPDFL43_19157"
     CDS             242158..243648
                     /locus_tag="HPDFL43_19157"
                     /note="COG0747 ABC-type dipeptide transport system,
                     periplasmic component"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein, family 5"
                     /protein_id="ZP_02164649.1"
                     /db_xref="GI:163757560"
                     /translation="MTNNPIMAAAVSILALSLGLGVAPAMAAKMDATIGMQLEPPNLD
                     PTGGAAAAIDEVVYANVFEGLTRFGADGSILPALAESWEISDDGLTYTFNLREGVKFH
                     DGSDFNADDVKFSLDRARADDSTNAQKALFADIASVDVVDPATVKVTLSKPNGSFLFN
                     TAWGDAVIVAPETAADNAAKPVGTGPFSFGEWVKGDRVDLVRNPDYWGEAVRLDKVTF
                     KFISDPTAAFAAMMAGDLDAFPVFPAPENLVQFEADPRFSVIIGSTEGETILAMNNKK
                     APLDNIKVRQAITHAIDRQAIIDGAMFGYGTPIGTHFAPHNPAYVDLTAQSAYDPEQA
                     KALLAEAGVSDLTLTLKLPPPSYARRGGEIIAAQLREVGIATEITNVEWAQWLEDVFK
                     AKNFDLTIVSHTEPMDIGIYGREDYYFQYGDADFKAIMADLANATDPAKRTELMQAAQ
                     KKIADDYVNGYLFQLARTGVADAKLKGLWPNSPTQANDMTGVYWEE"
     gene            243719..244669
                     /locus_tag="HPDFL43_19162"
     CDS             243719..244669
                     /locus_tag="HPDFL43_19162"
                     /note="COG0601 ABC-type dipeptide/oligopeptide/nickel
                     transport systems, permease components"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide/opine/nickel uptake family ABC
                     transporter, permease protein"
                     /protein_id="ZP_02164650.1"
                     /db_xref="GI:163757561"
                     /translation="MTAYLLRRFLSLSLSLVAASLVIFLVMEVVPGDPASFMMGINAD
                     PAAVVALRTQLGLDDPLPLRYLSWVAGLLQGDFGVSYTYRVPVSELISERVAISLPLT
                     LYALALSTLIAFPAGILAAAKRNSAADVSVMGATQLGVAIPNFWFAMILVLVFAINLR
                     WFSAGGFPGWEAGFWPAIKALTLPAIALALPQASILARVMRSSLIDTLDEDFMRTARA
                     KGLSRGQALRRHALRNALIPVLTIIGLQFSFLLAGGIIIENVFYLPGLGRLVFQAITQ
                     RDLIVVRSVVILLVFAVIVVTFLVDLAYAAADPRLRRRRA"
     gene            244666..245526
                     /locus_tag="HPDFL43_19167"
     CDS             244666..245526
                     /locus_tag="HPDFL43_19167"
                     /note="COG1173 ABC-type dipeptide/oligopeptide/nickel
                     transport systems, permease components"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide/opine/nickel uptake family ABC
                     transporter, permease protein"
                     /protein_id="ZP_02164651.1"
                     /db_xref="GI:163757562"
                     /translation="MSANPTDRSFLRMALGHPAFVTGFVLSAFFVILALVSFAWTPFD
                     PTKLDIASKLKTPSLDHWFGKDHFGRDMFSMIMVGARVSIAVAFVAVGVGMLLGVPLG
                     LYAAAHRGSLIDEFIMRGNDLVFAFPSLLLAIMITAVFGPGAVNAIIAIGIFNIPVFA
                     RLARGAALSLWTRDYILAARVAGKGRARISAEHILPNIANLLIVQGTIQFSLAILAEA
                     ALAYVGLGAQPPLPSWGRMLADAQTLISLAPHMALFPGFAIIITVLGLNLMGDGLRDL
                     FDPKLRRGRG"
     gene            245523..247133
                     /locus_tag="HPDFL43_19172"
     CDS             245523..247133
                     /locus_tag="HPDFL43_19172"
                     /note="COG4172 ABC-type uncharacterized transport system,
                     duplicated ATPase component"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide/opine/nickel uptake family ABC
                     transporter, ATP-binding protein"
                     /protein_id="ZP_02164652.1"
                     /db_xref="GI:163757563"
                     /translation="MNGLSISNLRVDIHGKTVLHDIDLELEPGKILGVVGESGSGKSM
                     TALSVMQLLPRGSQWTGRLEVAGNDLATMDEPALCQMRGRDVGMIFQEPMTALNPVRT
                     IGDQVAETVMVHTAAGRREALAIARTMLDRVGLPEDRFPLDRFPHDLSGGQRQRVVIA
                     QAIALRPKILIADEPTTALDVTTQAQILDLLRELVHEQDMGLMLITHDLAVVAGLADR
                     IAIMKDGAVVEAGPTRKIFEGMQHPYTRALLEASAHAPERRRRAEPQQVPVLSVSDVV
                     RDYQQPRRNLFVRPPPFRAVDHVGFEIFHGENVGLVGESGCGKSTLARAILALDPLQG
                     GEIKLNGHVFSSAGDGPHPELRARMQVVFQDPYGSFNPRHRVKRLVTEPFHLMKDRPQ
                     GIDLERRIDRALTEVGLSSADADKYIHEFSGGQRQRIAIARALIIEPALIVLDEAVSA
                     LDVSIRAQVLDLLADLSDRLDLSYLFISHDLSVVRAITDRVLVMKDGRIVEEGDTETV
                     FHNPQHPYTQTLVAATPSLEAALAESAG"
     gene            247182..248648
                     /locus_tag="HPDFL43_19177"
     CDS             247182..248648
                     /locus_tag="HPDFL43_19177"
                     /note="COG1012 NAD-dependent aldehyde dehydrogenases"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="ZP_02164653.1"
                     /db_xref="GI:163757564"
                     /translation="MPATLDAGFDTRQCLIGGRWINTRSGLTLPVEDPSTGQEIGRIA
                     RGAADDIEAAVIAARMSLSGDWGLMTAAERGRLLAKIGRAVEEHIEWLANLEAHDVGK
                     PLTQARADARALARYLEFYGGACDKIHGETIPYLTDYTVYTLREPHGVTGHIIPWNYP
                     MQILGRSVGAALAMGNAAVLKPAEEASLTALAFARIATDCGLPDGALNVVPGLGEEAG
                     AALCAHHDVNHLSFTGSLETGRKVQQAAAQNVVPVTLELGGKSPQIVFADADLDRALP
                     FLVNAGIQNCGQTCSASSRILVEASRHVEVVRLMSERYRSLTVGAAIEDQSVGPLISA
                     RQKTIVQGFLARADEDGLAPVAEGQMPKSAPMGGHYVRPTLYGDVDPSHALARDEIFG
                     PVQVIIPFRDEDEAVAIANGTDYGLVAGVWTQDGGRQMRLARAIRSGQVFVNNYGAGG
                     GVELPFGGVGKSGHGREKGFEALYGFSALKTVAVWHGK"
     gene            248667..249413
                     /locus_tag="HPDFL43_19182"
     CDS             248667..249413
                     /locus_tag="HPDFL43_19182"
                     /EC_number="1.1.1.100"
                     /note="COG1028 Dehydrogenases with different specificities
                     (related to short-chain alcohol dehydrogenases)"
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-(acyl-carrier-protein) reductase"
                     /protein_id="ZP_02164654.1"
                     /db_xref="GI:163757565"
                     /translation="MRLQGKTALVTGGASGFGAGIVRKFVTEGARVAIADINAQSAEA
                     FASELGDQVFAVGVDVSKNDSVVAMSELVLERFGGLDILINNAGVTHLPTALEEVSEE
                     EFDRVLAINVKSVYLTARHFVPVMKQNGSGAILNVASTAGVSPRPRLNWYNCSKGWMI
                     TATKTMAVELAPAGIRVNAINPVAGETPLLKSFMGEDTPEIRTKFLSTIPLGRFSTPE
                     DMGNAACFLCSDEAAMITGVAMEVDGGRCI"
     gene            249483..250775
                     /locus_tag="HPDFL43_19187"
     CDS             249483..250775
                     /locus_tag="HPDFL43_19187"
                     /note="COG0144 tRNA and rRNA cytosine-C5-methylases"
                     /codon_start=1
                     /transl_table=11
                     /product="Sun protein"
                     /protein_id="ZP_02164655.1"
                     /db_xref="GI:163757566"
                     /translation="MRLGGRLQAAIEVLTEIETRHRPVPDGLKDWGLSHRFAGSGDRA
                     AISNLVHDALRMKLSHGFMMNGDAPADLAVATLLRQWRISPEELTATLEGDRFAPEIP
                     SAESLADCLARDLAQAPAHVRADIPEWLAGSFERAFGPEWELEAQALTSRPPLDLRVN
                     TLLSNRDQVLEAFSDRDPKPTRLAPFGVRFEAGEGPQRQIAAASEVSFARGWFEIQDE
                     GSQLAAGLVDAQPGEDVLDYCAGGGGKSLAFAAMMNNEGRIFAYDADRRRLAPMVERM
                     RRAGADIIDIRERAADLNGLESKMDRVLIDAPCTGTGTWRRRPDAKWRISEKNITDRM
                     ADQDKVLDAACAYVRPGGELAYVTCSLLPEENTDRVKAFLQRHPEFETISLKQRWRSV
                     AADSEAPVPYADQNLGLLLSPRRTGTDGFYFAGFRRKS"
     gene            250841..251305
                     /locus_tag="HPDFL43_19192"
     CDS             250841..251305
                     /locus_tag="HPDFL43_19192"
                     /note="COG3476 Tryptophan-rich sensory protein
                     (mitochondrial benzodiazepine receptor homolog)"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="ZP_02164656.1"
                     /db_xref="GI:163757567"
                     /translation="MSKSNALILLAFVVFTVAGGSFIGYFSIPGAWYAALNKPVFNPP
                     NWIFGPVWTVLYILIGIAGARVWLNHRQSPLPKLWFAQMALNFAWPLVFFTAQRPDLA
                     LPVLIAMLIAILAFIALAWRRDRPAALMFIPYAAWVSFAGLLNGAIWWLNRG"
     gene            251400..251849
                     /locus_tag="HPDFL43_19197"
     CDS             251400..251849
                     /locus_tag="HPDFL43_19197"
                     /note="COG2050 Uncharacterized protein, possibly involved
                     in aromatic compounds catabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164657.1"
                     /db_xref="GI:163757568"
                     /translation="MMDKPDENFRNRVASSFARQEVMRTIGAELTKVDYGVIEIEMPF
                     RADLTQQHGFLHAGILSTALDSACGYAALSVMPHDAAVLTIEFKINLLSPGRGDRFLF
                     RGEVTKPGSTIIVTDGRAYAVADGPAKLIASMTGSMMVVRGREGIEG"
     gene            251846..252478
                     /locus_tag="HPDFL43_19202"
     CDS             251846..252478
                     /locus_tag="HPDFL43_19202"
                     /EC_number="3.2.2.9"
                     /note="COG0775 Nucleoside phosphorylase"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="ZP_02164658.1"
                     /db_xref="GI:163757569"
                     /translation="MTGEIKPAGDRRILYVMAAEAEYGQHLRARFAPLITGVGPVEAA
                     VAVSARLAQCGPDLPDCIVSLGSAGSNVLEQAGIYQVSSVSYRDMDARPLGFEKGRTP
                     FLDLPAVLPLPVIADDIASASLSTGANIVSGAAYDRIDAEMVDMETFAVLRAASRFAV
                     PVLGLRGISDGKSELNHIDDWTEYLHIIDEKLAQAVDRVEAAIASGAALA"
     gene            252488..254059
                     /gene="guaA"
                     /locus_tag="HPDFL43_19207"
     CDS             252488..254059
                     /gene="guaA"
                     /locus_tag="HPDFL43_19207"
                     /EC_number="6.3.5.2"
                     /note="COG0518 GMP synthase - Glutamine amidotransferase
                     domain"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GMP synthase/glutamine
                     amidotransferase protein"
                     /protein_id="ZP_02164659.1"
                     /db_xref="GI:163757570"
                     /translation="MNEILHTTHPDSILIIDFGSQVTQLIARRVREAGVYCEIVPFQL
                     ADDGFARMKPKGVIFSGGPDSVTREGSPRAPQAVFESGVPILAICYGQQTLCLQIGGQ
                     VEGGHHREFGRADVEILKSSPLFEGIWEVGKKYPVWMSHGDRVTVAPEGFEVIGTSPN
                     APFAICVNEAKRYYTTMFHPEVVHTPDGAKLLSNFVHKIVGLKSDWSMAAYRAEMVQK
                     IRDQVGSGKVICALSGGVDSSVAALLIHEAIGDQLSCILVDHGLMRMNEAADVVAMFR
                     EHYNLSLKLVDASDRFISQLEGEADPETKRKTIGRLFIEVFEEEAKKIGGADFLAQGT
                     LYPDVIESVSFSGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRVLGRELGLP
                     DSFIGRHPFPGPGLAIRCPGGITREKLDILRQADAIYLDEIRKAGLYDTIWQAFAVLL
                     PVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYPYDMDFLGKTATRIINEVKGINRV
                     VYDVTSKPPGTIEWE"
     gene            complement(254138..255403)
                     /locus_tag="HPDFL43_19212"
     CDS             complement(254138..255403)
                     /locus_tag="HPDFL43_19212"
                     /note="COG1850 Ribulose 1,5-bisphosphate carboxylase,
                     large subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="Ribulose-bisphosphate carboxylase"
                     /protein_id="ZP_02164660.1"
                     /db_xref="GI:163757571"
                     /translation="MNRITATYDIESPLGVDHAATVLAGEQSTGTFTRLAAETDELRE
                     RSAARIESLTITGSSPNPSLPSRKSGPAYERGTVTISWSLDNFGVSLPSLFSTLAGNL
                     FELAELSAIRLLDIGLPKEFALAHPGPQFGADGTRELMGGHEGPVIGTIIKPSVGLSP
                     SETAELVQTLIEAGIDFIKDDELQANGPHCPFEERLKLVSRVINLHAEKTGKRVMYAF
                     NITDEIDQMWRNLDLLQEHDGICAMVCMNSVGLTGLRAVRDRSPMIVHGHRAGWGLFS
                     RSPDIGISFTAFQKLWRLAGADHLHVNGLASKFTESDEVVAQSARSVQQPVCEGDGPQ
                     HLAMPVYSSGQTVWQIDPARRLLGNDDFIFCAGGGIMSHPSGIGAGVIALRQAAAAAK
                     EGVDIEMYAANAPELKSALETFKKPSIDL"
     gene            complement(255400..256785)
                     /locus_tag="HPDFL43_19217"
     CDS             complement(255400..256785)
                     /locus_tag="HPDFL43_19217"
                     /note="COG3395 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="type III effector Hrp-dependent outer"
                     /protein_id="ZP_02164661.1"
                     /db_xref="GI:163757572"
                     /translation="MDAPSKTLPDGPLIAWYGDDFTGASAVMEVLAFAGLPSMLFLEA
                     PTEEQLARFPDLKGIGVASTARAQSPGWMATELPAVFAKLSRLKPLLVHYKVCSTLDS
                     SPEVGSIGRAIEIGHDLFSPTTVPLLVAAPQMRRYQAFGHLFAGMGDEIYRLDRHPVM
                     SRHPVTPMNESDVARHVAKQSERLDVHCLSLEALAKRPGTYPSLPSDGDDRITLITLD
                     CMDASSESAAGHLIWNERHTNPFVVGSQGVTYALVRHWQESGLIPVAEAPEGIGEAEP
                     MVVVSGSVSPTTAEQIAWSKSNGFASIEFDAAAACGGTEAVEREIDRAVAAALNAIAA
                     NKDPLIHTAEGPDDPAVDAFKSAVAHSAHDMSSANQMIGEALGRVLHTVLLRTGTRRA
                     VVSGGDTSGHATRQLGIFALTALAPTIPGASIFRAHANGPMDGLELALKGGQMGSKDY
                     FGWIRSGGGRR"
     gene            256902..257732
                     /locus_tag="HPDFL43_19222"
     CDS             256902..257732
                     /locus_tag="HPDFL43_19222"
                     /note="COG2084 3-hydroxyisobutyrate dehydrogenase and
                     related beta-hydroxyacid dehydrogenases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164662.1"
                     /db_xref="GI:163757573"
                     /translation="MTKLALFGAGGKMGMRLGANLAKAPDFETLHVEVSDEGRARVRE
                     AYGVDCVDTDVALDGADIIVLAVPDTAIGKVSHAIIDRVKPGAMVFVLDGAAPFAGHL
                     PERADITYFVSHPCHPPIWNDETEMEAKRDYFGGIAAAQGIVNVLVQGPEEDYELGER
                     VGKTIYAPVVRSHRVTLQQFALLEPGLSETVNGSLMKVLRMAMDEVVRKGVPYDCARD
                     FLLGHMNIMGAVMFDQHQGVFSDAANKAIEFGIPVLMKDDWIRCFDDDEIAASVDRIT"
     gene            258192..258371
                     /locus_tag="HPDFL43_19227"
     CDS             258192..258371
                     /locus_tag="HPDFL43_19227"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164663.1"
                     /db_xref="GI:163757574"
                     /translation="MVGTLKQLALAAGEPVLSIRQENGLARLHVGEAEFVVNLTGVER
                     SGLGPYEWQAKIKQA"
     gene            complement(258368..259093)
                     /locus_tag="HPDFL43_19232"
     CDS             complement(258368..259093)
                     /locus_tag="HPDFL43_19232"
                     /note="COG2186 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="putative GntR family transcriptional regulator"
                     /protein_id="ZP_02164664.1"
                     /db_xref="GI:163757575"
                     /translation="MNKTNAADSKIVRLKLSDQVFERLREMLASGELAAGDTVPSERD
                     LMELFGVGRPAVREALQSMQSKGLITITHGGRSRVNALTAGLAFNQLDDIAKLLLSSE
                     PANIDYLKQVRHILELGTIKIAAQKCTSKDAAELAKLIEDQRSQIKSPEAFMKADIAF
                     HTRIASITTNPLIYSITEMMLTWLFEYHSSLLIWPGREETTLGEHATILSFLKSNDSE
                     GAVRAMEAHLNRSQSSFISAGKR"
     gene            complement(259239..260690)
                     /locus_tag="HPDFL43_19237"
     CDS             complement(259239..260690)
                     /locus_tag="HPDFL43_19237"
                     /note="COG0554 Glycerol kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase, putative"
                     /protein_id="ZP_02164665.1"
                     /db_xref="GI:163757576"
                     /translation="MFVLAIDQGTTNTKALVFAQDGEVVRSASASCHTDYPHPGWAEQ
                     SASEIWATTRQVIGDACAGIETEIAAIGISNQRETLVVWDATTGEPVGPAPIWQCRRT
                     ADECAALIEAGHSDEVSTLTGLGINPLFPASKLAWVLKNRPEPEDLHRVGRLRAGTVD
                     SWLLWNLTGRAVFATDHSNASRTLLFDTERLAWSPRLGEIFGAPIDCLATPMASDARF
                     GETAQGATTLPAGVPIHAMMGDSHAALFGHGVRGPGKVKATYGTGSSLMTLTRQRTLS
                     SHGLSGTIAWTQDGNTAHALEGNITVSAQAAAFMAEMLGLNGPAELSDLALQVSDNGG
                     VCFVPALAGLGAPHWQDDARGLVSGLSLGSRPAHLARATFEAIAHQVTDVLEAMEQDL
                     GHPLNGLSADGGASANSFLMQLQADFIGKPVERREIAEIGAFGVASMAAEALGMPIVA
                     GAKEIRIFDPATDATARRGARNEWKIAIARACR"
     gene            complement(260693..261661)
                     /locus_tag="HPDFL43_19242"
     CDS             complement(260693..261661)
                     /locus_tag="HPDFL43_19242"
                     /note="COG3958 Transketolase, C-terminal subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transketolase"
                     /protein_id="ZP_02164666.1"
                     /db_xref="GI:163757577"
                     /translation="MNAVEKVEGLFDCRKAWATTLETLAADDERIVAVVNDSVGSSNL
                     GGFQNAFADRLVNVGIAEQNMVGVSAGLANGGRIPFVSAASCFLTGRALEQIKADIAY
                     SGYNVKLVGQSSGIAYGELGATHHSIEDFAWLRALEPLTVIAPADPWETEMAVRWAAE
                     HEGPVYLRLSRMQVPDLGPDAHGRRDFTPGTARLMRKGDDVTILASGTIVHIALAAAD
                     ALASDGISARVFSVHTLNPLDEAAVLAAAEETGAIVTCEEALVRGGFGGAVAELTSSN
                     RPVPVERVGFKTFQTTGSVDWLFEQNGLTPIGIADASRRALARKTG"
     gene            complement(261658..262494)
                     /locus_tag="HPDFL43_19247"
     CDS             complement(261658..262494)
                     /locus_tag="HPDFL43_19247"
                     /note="COG3959 Transketolase, N-terminal subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase, N-terminal subunit"
                     /protein_id="ZP_02164667.1"
                     /db_xref="GI:163757578"
                     /translation="MAMPLEDEDTRLPQIRQKANWMRRRALEMVHGKKLGHIGGDFSA
                     TDILATLYFGVLRYDPVKPDWPERDRFVMSKGHATGALYTVLCAAGYFPEDWLKTYMG
                     PGSRLNGHPNRNYLPGVEANTGPLGHGFPIALGMAIAGQMSGSAHRTFVLTGDGEQQE
                     GSNWEAAMTAGHKQLQDLTLIIDRNRLQQGARTEDTVSLDPLGEKYRSFGWDVIEVDG
                     HDHAKLLNTLDAAPAQGRPRCIIANTIKGKGVSFMEDKAKWHHGVPNDDEFELAMKEL
                     SR"
     gene            complement(262504..263970)
                     /locus_tag="HPDFL43_19252"
     CDS             complement(262504..263970)
                     /locus_tag="HPDFL43_19252"
                     /note="COG2407 L-fucose isomerase and related proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164668.1"
                     /db_xref="GI:163757579"
                     /translation="MDRTVNRPVSLGVVIGSRAFFSPAPCKQARDAVLAQMERLGINA
                     VTLPFEATDNGAVQSISDAKLYADHFAANRDKIDGIVICLPNFGDEIAVAELVGRAKL
                     DVPILLQACNDEIDKVDVHSRRDAFCGKISISNNFWQYGVPFTETTNHTVDIESDEFA
                     ADLDRFARICRTVGGLKGARIGAIGARTGPFQTMRYSEKLLQTSGVTVVTVDLSEMMH
                     AAGQIADDAPELLEKLRKIEAYGTIPTYIKSEQVLTQAKWTLAVNRWIDENECDASAI
                     QCWRSLQDNFGCATCLTMSMMGEELMPSACEVDVMGAVSMYALTLASGAPAAILDWNN
                     NYGNSPDMCVCTHCGNYPKSFIGDTPEISELDVLGETIGRGKCFGAVKGKVKAGDMTY
                     FRLSSDDNAGRLKCYVGEGEFTDDPFGMDGGIAVTRVKDLRRLMRFVTQNGFEHHVAM
                     VRGQHADVVNEAVTRYLGWATYHHGGDPEPQLFIPNRF"
     gene            264228..265178
                     /locus_tag="HPDFL43_19257"
     CDS             264228..265178
                     /locus_tag="HPDFL43_19257"
                     /note="COG1879 ABC-type sugar transport system,
                     periplasmic component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative substrate-binding periplasmic protein
                     component of ABC transporter"
                     /protein_id="ZP_02164669.1"
                     /db_xref="GI:163757580"
                     /translation="MSKLTLKRRTFLGSVAVAAVVAAKPAWAQSKGTIAIITPSHDNP
                     FFKAEADGADAKAKELGYDTVILVHDDDPNKQSQQFDTVIAQGVVAIILDNAGADASV
                     AAVQRAKDAGIPSFLIDREITATGVAVSQIVSNNYQGAQLGAEEFVVQMGESGKYAEL
                     LGKESDTNAGIRSQGYHDVIDQFTDLEMVAQQTANWSQTEAFSVMESMLQANPDIKGV
                     ISGNDTMAMGAMAALEAAGRSDVIVVGFDGSNDVRDSILAGGIKATVLQPAYQQAQLA
                     VEQADKFLTAGSTGLDEKQLMDCVLITADNAGQLDNFQLS"
     gene            265241..265882
                     /locus_tag="HPDFL43_19262"
     CDS             265241..265882
                     /locus_tag="HPDFL43_19262"
                     /note="COG5618 Predicted periplasmic lipoprotein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164670.1"
                     /db_xref="GI:163757581"
                     /translation="MKQAIPVILILCLAALPGCKIIHESEKTEVVSVGPEGDAARNQA
                     RLEETFDSQLLPLITTGPLDVAGLRAALASDGLEAAGSAHGNQGSGRGAAWNFPVQGD
                     GIIVAAKLDTSARTVSVDVDKDGVGDVTVQLGPVIRGTALRDVAPFYNFDDFRDQIEF
                     AKLARAINDRIKPLLKVPDGDLVGMTMSFVGVTPLKSPQETMVVTPVEMSFAK"
     gene            265879..267408
                     /locus_tag="HPDFL43_19267"
     CDS             265879..267408
                     /locus_tag="HPDFL43_19267"
                     /note="COG1129 ABC-type sugar transport system, ATPase
                     component"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter, ATP-binding protein"
                     /protein_id="ZP_02164671.1"
                     /db_xref="GI:163757582"
                     /translation="MSEDHPIGLSIRGAVKVYPGTRALKGVDFDIRMGAVNVLVGENG
                     AGKSTLMKIIAGVEELNEGEILLNGEAVTFRSKDDAVRAGIGIVFQELNLFAEMTVAE
                     NVFIGRERARMGIDIDGDAETEQTSLLMKRLEQTIAPDTVLGHLRIGQQQIVEIAKAL
                     AQDVNILILDEPTSALSAHEVDVLFRVIEDLKRQGVGIVYISHRLEELIRVGDYITVL
                     RDGEITGARSMQGVDIPWIVHAMIGDKSKDFASATNHEFGVEAFRAEDVCLPRPGGGF
                     IVDHLSLSVRAGEVLGLYGLMGAGRTEFLECVMAQHHGSTGRYYVYAEELRSHSVAGR
                     ISKGIALVPEDRKRDGLVQIMSIRENLTLSSIRRIARLFHLDPVREVKKAAEYIKRLT
                     IKVSNPENPVSSLSGGNQQKVVIGKALMTEPRVLLMDEPSRGIDIGAKAEIYRLIRKL
                     ASEGLAILFVTSDLEEVMALADRIAVMADGRKTGEFPNTARAADIIAAATPRKQKDTA
                     A"
     gene            267405..268469
                     /locus_tag="HPDFL43_19272"
     CDS             267405..268469
                     /locus_tag="HPDFL43_19272"
                     /note="COG1172 Ribose/xylose/arabinose/galactoside
                     ABC-type transport systems, permease components"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter, permease protein"
                     /protein_id="ZP_02164672.1"
                     /db_xref="GI:163757583"
                     /translation="MSEMITAAPRPAARPNFLLLVLEMRTYLALLLVFAYFAIMAPNF
                     LSVDNAVLISKHVAINAFLAIGMTFVIITGGIDLSVGSVVGLTGMVAGYLVLNGIYIG
                     GGYTVYFNTIEIVAIVCCVGIFVGWINGILITRLKVAPFIATLGTLYVARGVSLLLSD
                     GRTFPNLNGNPEYGSDTFPMIGSGTVFGLPVMIWALIGVTLLAIYISRRTPLGRHIYA
                     TGGNERSAALSGVNVDRTKLFVYMFSGLMAAIVGIIIASQLKASHPATGEFFELNAIA
                     AAVLGGTSMAGGRGRIWGTIVGAFVIGILADGLIMMGVSSFWQMVIKGLVIIAAVVID
                     QFQSRLQSRIALAQETEGGR"
     gene            268555..269319
                     /locus_tag="HPDFL43_19277"
     CDS             268555..269319
                     /locus_tag="HPDFL43_19277"
                     /note="COG1349 Transcriptional regulators of sugar
                     metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR-family transcriptional regulator"
                     /protein_id="ZP_02164673.1"
                     /db_xref="GI:163757584"
                     /translation="MLSTVRRKRIIDWIEEEGSARVRDLAAAFEVTEATIRQDLERLE
                     KAGQVTREHGGAFLNSVPSQVASHALHHRIEMDRKQKIGALAASLVADNETIILDAGT
                     TTTEVATRLTVRKNLTVITNALNIAMVLGSVPGFSVHMPGGEFKPPTLSLTGDKSVDY
                     FRDILAGKLFLATAGVDVELGLTYPSFADLQLKQAMIRAAQHVYLVADASKINKPSFT
                     RLGDLDLVQTFITDDGISDKDAKSIEARGIELLIAR"
     gene            269353..269700
                     /locus_tag="HPDFL43_19282"
     CDS             269353..269700
                     /locus_tag="HPDFL43_19282"
                     /note="COG1393 Arsenate reductase and related proteins,
                     glutaredoxin family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164674.1"
                     /db_xref="GI:163757585"
                     /translation="MTVTIYGIKNCDTMKKARKWLADQGIEAVFHDYKSAGIDAAHLE
                     RWCVEAGWETVLNRAGTTFRKLDEAEKQDLDQTKAIRLMLAQPSMIKRPVIEAGDRVL
                     VGFKPELYAQFFG"
     gene            269815..271122
                     /locus_tag="HPDFL43_19287"
     CDS             269815..271122
                     /locus_tag="HPDFL43_19287"
                     /note="COG1231 Monoamine oxidase"
                     /codon_start=1
                     /transl_table=11
                     /product="amine oxidase, flavin-containing"
                     /protein_id="ZP_02164675.1"
                     /db_xref="GI:163757586"
                     /translation="MTAAAPRLARGNRNPDVVVIGAGMAGLAAARDLMARGMSVHILE
                     ARDRIGGRVFTNRDVPGWPVDMGASWIHGIDGNPLTRLADQGGLARIETSWEPRPTFG
                     PGGVRIDLDDASELAGKLLEAGRDRVEDRDYDVSLADAVQGTAGWRGLKPGDRRLMRH
                     FANSDIEHEFAADWNDLSAWYYDDSGAYDGPDVIFPDGYGDLATYLAKGPSITTGEIV
                     TGLQRRGDTVKIITQSDTTYQASHVILTVPLGVFKAGRIAFSHPLERSRTKAIDSIGM
                     GLLNKCWLRFERTFWPHNTDAFGFVGELDGHWAEWFSLSRATGEPTLLGFNAGTAARE
                     IEKLDDLETVERAMEVLRSIFGSGIPDPVTWKISRWNSDPFALGSYSFTAVGSDRGSR
                     RALAGADWDGRLLFAGEATHEEHPATVHGAYLSGQEAARLIAG"
     gene            complement(271199..272791)
                     /locus_tag="HPDFL43_19292"
     CDS             complement(271199..272791)
                     /locus_tag="HPDFL43_19292"
                     /note="COG1570 Exonuclease VII, large subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="putative exodeoxyribonuclease VII large subunit"
                     /protein_id="ZP_02164676.1"
                     /db_xref="GI:163757587"
                     /translation="MSSLLDDSPTNAAEFTVSELSGSIRRTVEDAFGNVRVRGEISGY
                     RGPHSSGHAYFSLKDDRARIEAVIWKGVFSRLKHRPEEGLEVIATGKITTYAGSSKYQ
                     IVIESIEPAGAGALMALIEERRCKLAAEGLFDEARKQLLPYMPLVIGVVTSPTGAVIR
                     DILHRIEDRFPVHVIVWPVRVQGDTSGNEVANAITGFNALAPGGRIKRPDLIIVARGG
                     GSLEDLWGFNDEAVVRAAAESDIPLISAVGHETDWTLIDHASDRRAPTPTGAAEMAVP
                     VKADLEAHLAGLAARLKSAQSRMLDRRREAVRGLTRALPTLDSVLALPRQRLDRSGQG
                     LGQALQLNTANRRRGFERQAARITPIALVSAIREKRQVLRDRATRADRSLERRVEVLR
                     TGLERHALVLSAVPRRITETQTHARERLTGLGRRGETALTQLIGQHKRALGAQARMLK
                     SLSYQSVLGRGYAVVRNQDRKLLSRAEQVQSGEMIGVEFADGEVSALVNGTGAEAPSS
                     KPKKQTRTKANKTPEPGQGSLF"
     gene            272987..274042
                     /locus_tag="HPDFL43_19297"
     CDS             272987..274042
                     /locus_tag="HPDFL43_19297"
                     /note="COG3608 Predicted deacylase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164677.1"
                     /db_xref="GI:163757588"
                     /translation="MKTEIETIPGETPGIAYELIVHHLSGSDPAAPRVYIQSALHADE
                     RPGVAVMHYLIPMLEHAEAEGRLLGSLTLVPHANPIGAAQHLFSNHMGRFSGATRVNF
                     NRDFPVPGKDGVRHLDNASSATFAERRLKSRLLELADGCPIVLDLHCDDEGVQYLYVP
                     EILWPEMSDLAACLDAEAALLWDKGSDRAFEEAAFEQMRASAADGDLSGHCVTTVELR
                     GQIDVDAQTGLKDAEGIYRFLQARGVVAGDAAAPDLRGGFVGKPIRHVDMIEAPAGGT
                     ILFHAKPGDRVEAGQLIAEIVVNPGFKDGCVEVRAPQGGFVLTRRARRFIRMGDNLFK
                     IIGDEALVAGYEGALED"
     gene            complement(274087..274998)
                     /locus_tag="HPDFL43_19302"
     CDS             complement(274087..274998)
                     /locus_tag="HPDFL43_19302"
                     /note="COG3302 DMSO reductase anchor subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase, C subunit,
                     putative"
                     /protein_id="ZP_02164678.1"
                     /db_xref="GI:163757589"
                     /translation="MHPAVSVIFFTVASGAGFGLIFLLGLGFPVSGGAGRAFLISLAG
                     GGLAVAGLLSSTFHLGHPERAWRALSQWRSSWLSREGICAIATLVLFGIYALYWMVIG
                     VRLDVLGLVIAVGAAATVFTTSMIYAQLKTVPQWQSALTPLVYLAFALGSGWLLASAF
                     GSFQSPEPWGILLVGLAWGAKWLWWTRAARTRLADTGSTPETATGLGFIGKVRLLEKP
                     HSGDNYLTREMVHKIGRKHARSLRRVALVLGGVVPVAILALVALSGAPAILNILAALS
                     MLAGLLAERWLFFAEAEHSVSLYYGHR"
     gene            complement(275003..275749)
                     /locus_tag="HPDFL43_19307"
     CDS             complement(275003..275749)
                     /locus_tag="HPDFL43_19307"
                     /note="COG0437 Fe-S-cluster-containing hydrogenase
                     components 1"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster-binding protein"
                     /protein_id="ZP_02164679.1"
                     /db_xref="GI:163757590"
                     /translation="MTTLPQTTEKRLGLVIDLDTCVGCHACAVNCKEWNTGAGASPLG
                     DVDAYGADPSGAWLNRIHTFEVTPADAPAQIVHFPKSCLHCDDAPCVTVCPTGASHKR
                     SEDGIVLVTEDMCIGCGLCAWACPYGAREMDPVENVMKKCTLCVDRIYSDTLAEEDRI
                     PACVRTCPSNARHFGDFNDPQSDVSLLVVERGGVELMPEMGTSPVNRYLPPRPKTRSQ
                     TAPLAAVAADLPKAEGGFLGWLDAALEKLG"
     gene            complement(275746..278646)
                     /locus_tag="HPDFL43_19312"
     CDS             complement(275746..278646)
                     /locus_tag="HPDFL43_19312"
                     /note="COG0243 Anaerobic dehydrogenases, typically
                     selenocysteine-containing"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase, molybdopterin-binding protein"
                     /protein_id="ZP_02164680.1"
                     /db_xref="GI:163757591"
                     /translation="MAHKGRGTTVKTGVAEAGERMNHISRAEDAGDGKTEIRKTTCYM
                     CACRCGINVHMKGEKVHYIEGNRDHPINKGVLCAKGSAGIMQHYSPARLKKPLLRTGK
                     RGEGKFKEIEWDEALGLATQWLGKVRSTDPRKLAFFTGRDQSQSMTGWWAQQYGTPNY
                     AAHGGFCSVNMAAAGIYTMGGAFWEFGAPDWERTELFMIFGVAEDHDSNPIKMGLGRL
                     KARGVKVIGVNPVRTGYNAIADEWLGITPGTDGLLILALVHELMRTGQIDVDYLIRYT
                     NAPWLVIDDPDASDHGLFARDEQGVALVADRKTGAIVTSSEAGIKPAMKGQFTLPDGR
                     KATPVFELLAKAYLDPKYAPAAVAEQTGIDADTVTRIASEIADAAFKREIVIERPWTD
                     MKGERHERMIGRPVAFHAMRGISAHSNGFQTCRALHLLQILLGSVDCPGGFRFKPPYP
                     RPVAGQPRPHGGACADAALAGPHLGYPRGPEDLLLEADGETAQRIDKAFSWDAPLSAH
                     GLMHMVISNAHARDPYGIDVLFLYMANMAWNSSMNTTSVMDMLTDTDENGDYVIPKII
                     YSDAYSSEMVAFADLILPDTTYLERHDCISLLDRPISEPEALCDSIRWPVVEPDRDVR
                     GFQSVLLDLGARLKLPGMVNEAGEAIYKDYADYIVNHQRKPGVGPLSGWRGENGDKTG
                     RGEPNPDQLKRYIENGGFSMVHVPEEAQFFKHANRAWSDWAIANGLQDGPVENIFQLY
                     LEPLRKFQLAAEGKIKPSPPEHHRARIQRCFDPLPCWYPPFYEDGLEPDAYPLHAITQ
                     RPAAMYHSWGSQNAWLRQIHGENALYVPGDVCDREKLTDGDWALVNSPSGEIRVQVRR
                     MDAVNGSTLWTWNAIGKRAGAWALGKDAPETTRGFLLNHLIDELLPPKGDGRRWANSD
                     PITGQAAWFDLRVSIRRDPDQSGIHSQPSHGAQGSPVGSGPGQVAFGRETAE"
     gene            complement(278907..279233)
                     /locus_tag="HPDFL43_19317"
     CDS             complement(278907..279233)
                     /locus_tag="HPDFL43_19317"
                     /note="COG0640 Predicted transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="Predicted transcriptional regulator"
                     /protein_id="ZP_02164681.1"
                     /db_xref="GI:163757592"
                     /translation="MPDALDMLEMEPRMNEAAKLMEMLSQPVRLRILCILLDGEQSVL
                     KLADMAGLSQPAMSHHLRKLRDADLVNTRRDAQTIYYSLKGQEVSAVLDVLHGLYCRP
                     RVADAD"
     gene            complement(279295..280320)
                     /locus_tag="HPDFL43_19322"
     CDS             complement(279295..280320)
                     /locus_tag="HPDFL43_19322"
                     /note="COG1609 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, LacI family protein"
                     /protein_id="ZP_02164682.1"
                     /db_xref="GI:163757593"
                     /translation="MQKRAPRITDVAKLAGVSTATVSRALSKPDTVAESTRNAVLAAA
                     QESGYRVNLSARNLRRQRTGAIVVMVPDLGNPFFSRILSGIEEGLSKSDLNMLVVDTR
                     QAHLKPQLLLNYLHATRADGIIALDGSLPDTVLSATLSGPDAPPIIFACEWTPADRFP
                     SVRVNNERGARLAIAHLTDLGHRSIGMISGPRDNVLTGTRSQGVAAEMAARNLALDPA
                     HVFDGDFSIEAGAKAAAAWLGLPNRPSAMFCQSDQMAFGFISELTRLGISTPEDVSVV
                     GFDDIDIARRFIPALTTVHQPRTALGLAAAEIIIRHIGAPDDRSSKPNILDVELIARD
                     STRRVID"
     gene            280575..281804
                     /locus_tag="HPDFL43_19327"
     CDS             280575..281804
                     /locus_tag="HPDFL43_19327"
                     /note="COG1653 ABC-type sugar transport system,
                     periplasmic component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative solute-binding component of ABC
                     transporter"
                     /protein_id="ZP_02164683.1"
                     /db_xref="GI:163757594"
                     /translation="MDIYNTILAGASVLALTASAQATELEVTHWWTSGGEAAAVAEFA
                     KAFDATGNKWVDGAIAGGGGTARPIMISRITGGDPMAATQFNHGQQALELVEAGLMLD
                     LTDVAEAEGWKDVIFPQSLLDSCTVDGRIYCAPVNIHSPEWLWLSNKAFEEAGVPVPT
                     NWGEFVAAAPALEAAGKIPLALGNQPWQSNLAFGAMQIAVAGLDTWKAVNVDKNMDVA
                     AGPEYAKVFEAAANARKLAAKSTVQDWNQATNLVITDQAGGQIMGDWAQGEFAVAGKV
                     AGQDYTCLPGLGVNAYLSTGGDAFYFPKIDDPEIEKAQKELAAMMVSKQVQVAFNLKK
                     GSLPIRGDVDLAAANDCMKKGLEILASGNLVPTGDMVWSPDIVKQNEDLMVEFWKTDM
                     APEDAHAQWVNNLKSGS"
     gene            281857..282774
                     /locus_tag="HPDFL43_19332"
     CDS             281857..282774
                     /locus_tag="HPDFL43_19332"
                     /note="COG1175 ABC-type sugar transport systems, permease
                     components"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter, membrane spanning protein
                     (sugar)"
                     /protein_id="ZP_02164684.1"
                     /db_xref="GI:163757595"
                     /translation="MTLGEAIFMSQVQRPTQLFRNLSSKIAALPMIFTALVVFVGGTL
                     WTVFYSFTNSKLLPREKFVGFDQYERLWSTSRWVISIENLMLYGVFSLIFSLVIGFCL
                     AALLDQKIRFEDTFRTILLYPFALSFIVTGLVWQWLLNPQFGVQAIVRGWGWESFTFD
                     PLYNPDIVMFGLLIAGLWQGTGFIMCLMLAGLRGIDEDIWKAARVDGIPMWKTYLFII
                     IPMMRPVFITTLVIIASGIVKLYDLVVAQTSGGPGNASEVPAKYVYDYMFQAQNLGQG
                     FAASTMMLLTVLIVLIPWAYLEFGGKKHG"
     gene            282767..283681
                     /locus_tag="HPDFL43_19337"
     CDS             282767..283681
                     /locus_tag="HPDFL43_19337"
                     /note="COG0395 ABC-type sugar transport system, permease
                     component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transport system permease abc
                     transporter protein"
                     /protein_id="ZP_02164685.1"
                     /db_xref="GI:163757596"
                     /translation="MVDAVAVSPVLEPGPSGRKPRKTLSRRNIFLYGTLIMVAMYYLL
                     PLYIMVVTSLKGMPEIRLGNIFAPPVEITFEPWVKAWSEACTGLNCDGLSRGFWNSVQ
                     ITVPSVIVSIAIASVNGYALANWRFKGADVFFTILIFGAFIPYQVMLYPIVILLREMG
                     IYGTLWGLVVVHTIFGMPILTLLFRNYFTSLPEELFKAARVDGAGFWGIFFKIMLPMS
                     LPIFVVAIILQVTGIWNDFLFGVVYTKPDIYPMTVQLNNIVNSVQGVKEYNVNMAATI
                     LTGLVPLTVYFISGKLFVRGIAAGAVKG"
     gene            283685..284770
                     /locus_tag="HPDFL43_19342"
     CDS             283685..284770
                     /locus_tag="HPDFL43_19342"
                     /note="COG3839 ABC-type sugar transport systems, ATPase
                     components"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ATP-binding component of ABC
                     transporter"
                     /protein_id="ZP_02164686.1"
                     /db_xref="GI:163757597"
                     /translation="MTSVAIKDLCLNFGSVKVLKNLNIDIDEGEFLVLLGPSGCGKST
                     LLNCIAGLLDASEGQIFIKGKNVTWEEPKDRGIGMVFQSYALYPQMSVEGNLAFGLKN
                     ARMPKDEIAKRIARAAEILQIEPLLQRKPAQLSGGQRQRVAIGRALVRDVDVFLFDEP
                     LSNLDAKLRAELRVEIKRLHQRLKNTMIYVTHDQIEALTLADRIAIMRNGIIQQLAGP
                     HEIYNRPVNLYVAGFMGSPSMNFLHGELAEQSGETVFLSNGVTFSLRGYETETALEPG
                     RKVVLGVRPEHIRVDEDANGGETHEAVFDIEEPMGSDNLLWLKYAGQTLSVRTAATGR
                     YSHGGSVRLGFDMSVASLFDATSELRI"
     gene            284838..287306
                     /locus_tag="HPDFL43_19347"
     CDS             284838..287306
                     /locus_tag="HPDFL43_19347"
                     /note="COG3250 Beta-galactosidase/beta-glucuronidase"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-mannosidase precursor"
                     /protein_id="ZP_02164687.1"
                     /db_xref="GI:163757598"
                     /translation="MNTMYEYEAAMGVDLAGEWSLHSADGEHRAVITLPGDVHSALEH
                     AGVIPDPYFGRNEELVQWVVERDWVVERTFMLPDPSGSWYLDIDHLDTVAVVFVNDVP
                     VLSADNCFRRFRPDVIHALRQGENTIRIIFHSSLSAGADRQARQPFYVPYHKGNSPLP
                     NGNMLRKPQCHFGWDWNIAIGPLGLYGTIALRRLDPARIEHVETEQTHHGDGLVDLKV
                     TVTVYSADPAAIQMHLDLDGERIRLDIGTRAGETRVTHVFEIEQPRLWWPSGSGEQAL
                     YTLKVEIAGESVTRQIGLRTVELITDKDETGSRFALKLNGREIFCRGANWIPADALFS
                     RTSPEKTEDLLTSAVAANMNMIRVWGGGFYEADWFYDLCDRLGLMVWQDFMFACNLYP
                     CTDEFLENVAAEVDYQVRRLASHASIVLWCGDNELVGALTWFEESVNNRDRYLVAYDR
                     LNREIEQGVRKASPQAIWWPSSPASGYLDYGDAWHADGSGDMHYWSVWHENKSFDNYR
                     AVKPRFCSEFGFQSYTSLPVIESFAGKADMNISSPVIELHQKNAGGNERIAGTMFRYF
                     RFPKDFASFVYLSQIQQGLAIGTAVDHWRSLKPHCMGTLFWQLNDTWPVASWSSLDYG
                     GSWKALHYMARRFFQPVAVAAIPSEDATNIILSMVNDTAETVTIDVNLFALSTAGDRV
                     PIKTVQGDCPPDRAEVLLHLDSLEIPAGGLLAWSFVASNGMKGEGHFINGAYKSLELF
                     PSGIETEISALPDGTFELTVTASGLALFIMIESEMPGRYSDNAFDLARGESRRIIFTP
                     GTPVSSDQPPAFRLHDLYSSQSAD"
     gene            287362..288141
                     /locus_tag="HPDFL43_19352"
     CDS             287362..288141
                     /locus_tag="HPDFL43_19352"
                     /note="COG1082 Sugar phosphate isomerases/epimerases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164688.1"
                     /db_xref="GI:163757599"
                     /translation="MNKLAFQLYSARNFQPFSAFYPVLAAAGYDSVEGYGGIYADLDD
                     AAVEALKIDLDANGLIMQTAHFGLDMLESDPAKVIRIAKALGMERVYCPHIAADLRPT
                     NRIGWQAFAARLEAVGEKISAAGLGFGWHNHDFEFQALDDGTVPMQILLDTAPKIEWE
                     ADIAWIIRGGADPFDWINRYGDRITAVHVKDIAPQGEAMDEDGWADVGHGTVDWARLF
                     TELRAKTPARLFIMEHDNPADATRFATRSIEWVRNTLEQQA"
     gene            288138..289274
                     /locus_tag="HPDFL43_19357"
     CDS             288138..289274
                     /locus_tag="HPDFL43_19357"
                     /note="COG0673 Predicted dehydrogenases and related
                     proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164689.1"
                     /db_xref="GI:163757600"
                     /translation="MTGKLGVGIIGCGNISTSYLGLAPMFRGFEIRACADINAQAAQA
                     RADEYGIRAETVDGLLAADDIDIIVNLTVPAVHYEVSAKALDAGKHVYSEKPFVLSVE
                     EGRDLAARAEKHGLRVGSAPDTFLGGAHQLARHLVDHGDVGRIIGGTCHVLSPGMEHW
                     HPNPDFFFKPGGGPVLDLGPYYISNLVQLIGRVRRVVAMSSIPTPERKITSKPRHGEM
                     ISVETPTTIHAVLEFANGALVTLGASWDVKAHGHRPMELYGTEASLIVPDPNFFGGEV
                     QLIAQGGATKDLPDWSHPLGVPNQQHGQGMMANYRTVGLADMAIAIMENRAHRCSLDF
                     ALHVVDVMTAILHSGADGQFKTLTTSCAQPDPLGVVEAAALLQN"
     gene            289332..290342
                     /locus_tag="HPDFL43_19362"
     CDS             289332..290342
                     /locus_tag="HPDFL43_19362"
                     /note="COG0667 Predicted oxidoreductases (related to
                     aryl-alcohol dehydrogenases)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164690.1"
                     /db_xref="GI:163757601"
                     /translation="MVYRRTGRSGLKLPALSLGLWHNFGGDTHHEIKREMCRTAFDLG
                     ITHFDLANNYGPPPGSAESAFGEILKTDFHGLRDEMIISSKAGYGMWPGPYGEWGSRK
                     YLIASCDQSLKRMGLDYVDIFYSHRFDPDTPLEETMQALDYIVRSGRALYAGISSYNS
                     KRTKEAAAILKDLGTPCLIHQPSYSMINRWVEDDGLLDTLDEEGIGSIVFSPLAQGML
                     TSKYLGGIPEDSRAAQEKSLNADFLNERNLANIRGLDAIAKRRGQTLAQMAIAWVLRG
                     GRVTTALIGASRPQQIIDCVGALDNLDFTEAELSEIDTFARDADINLWAASSERKGPK
                     RK"
     gene            290339..291949
                     /locus_tag="HPDFL43_19367"
     CDS             290339..291949
                     /locus_tag="HPDFL43_19367"
                     /note="COG3507 Beta-xylosidase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative beta-xylosidase protein"
                     /protein_id="ZP_02164691.1"
                     /db_xref="GI:163757602"
                     /translation="MITNPILPGFNPDPSICRAGADYYIATSTFEWYPGVQIHHSTDL
                     VNWRLVCRPLDRESQLDMRGNPDSCGVWAPCLSYADGLFWLVYTDVKRLDGNFKDAHN
                     YIVTAPSITGPWSDPVYVNSSGFDPSLFHDDDGRKWFLNMVWNHRTDSVGGSPKHPAF
                     AGILLQEYDADAGKLIGKPQNVFAGSDHGLVEGSHVFKRDGWYYLTVAEGGTGYEHAV
                     TMARSRALAGPYELHPDTFLMTSKDAPEAPLQRAGHGQMIETPDGEVYHTHLCSRPLP
                     GLRRSPLGRETALQKCTWGEDGWLRLAQRGLVPDVTVESPDPESRRTPPVAVRRTFAG
                     ERLPDEFQWLRTPHPDRLFTLTGSALRLHARESIGSWFEQALVARRQEHLKFRAETTL
                     RFEPGNFQQAAGLVHYYNRHKFHFLAVTWHEQLGRSLSILSCPGDWPDSRMEFPLKTP
                     VALPGDGPVDLAMDVDGAEIVFSHRIPGGEWQRIGPMLDASVISDEGGRGEHASFTGA
                     FVGMAAFDTSGSAIAADFEQFAYMPEEG"
     gene            291946..292782
                     /locus_tag="HPDFL43_19372"
     CDS             291946..292782
                     /locus_tag="HPDFL43_19372"
                     /note="COG0823 Periplasmic component of the Tol biopolymer
                     transport system"
                     /codon_start=1
                     /transl_table=11
                     /product="putative TolB-like protein"
                     /protein_id="ZP_02164692.1"
                     /db_xref="GI:163757603"
                     /translation="MMRSALCIYEIATGTVEEVLATPRLIEAPNWTPDGVALIVNGDG
                     RMFRVPLEAPDLVPIDTSHAINCNNDHGVSPDGERLVISDSTDTGQSCIWVLPIAGGI
                     PERITGQVPSWWHGWSPDGSTLAYVGRRDDGFGIYTISLAGGDEEHLISGGGHYDGPD
                     YSPDGAFIWFNSDRTGSMDLWRIPAAGGEPQQMTRDDRANWFPHPAPDGRSVLYLSYA
                     PRTEGHPRDRDVELRLLDLADQSVRTLLSLFGGQGTINVPCWSPDGSRFAFVRYQPAE
                     AN"
     gene            complement(292826..293038)
                     /locus_tag="HPDFL43_19377"
     CDS             complement(292826..293038)
                     /locus_tag="HPDFL43_19377"
                     /note="COG2900 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164693.1"
                     /db_xref="GI:163757604"
                     /translation="MNADDEARLMRLEELVAHQQAAIEDLSRQLTEGWKENEKLRRDL
                     ARLADRFEELEDGAEAPAANQKPPHW"
     gene            complement(293035..293424)
                     /locus_tag="HPDFL43_19382"
     CDS             complement(293035..293424)
                     /locus_tag="HPDFL43_19382"
                     /note="COG0824 Predicted thioesterase"
                     /codon_start=1
                     /transl_table=11
                     /product="Putative thioesterase"
                     /protein_id="ZP_02164694.1"
                     /db_xref="GI:163757605"
                     /translation="MELQTRWEDNDIYGHMNNVVHYKLFDTAVNQWLIEAGLLDPLNG
                     SMIGLVVETGCRYHAEAAFPDRISAGIAVERLGGSSVTYEIGLYRNEAQKAFADGRFV
                     HVYVDKATRRPVALPELWREKLAEICR"
     gene            293765..295300
                     /locus_tag="HPDFL43_19387"
     CDS             293765..295300
                     /locus_tag="HPDFL43_19387"
                     /note="COG3845 ABC-type uncharacterized transport systems,
                     ATPase components"
                     /codon_start=1
                     /transl_table=11
                     /product="putative atp-binding abc transporter protein"
                     /protein_id="ZP_02164695.1"
                     /db_xref="GI:163757606"
                     /translation="MNDIAIELKGIDKSFGLVQANKNINLTVRKGTIHGIIGENGAGK
                     STLMSILYGFYQADKGDIFIDGRKTVIKDPNAAIASGIGMVHQHFMLVENFTVLENVM
                     LGAEESQILTAGISKARDELRRLEEEYELEVDPDAIIEELPVGIQQRVEILKALYRGA
                     EILILDEPTGVLTPAEADHLFRILEQLKAEGKTIMLITHKLREIMAVTDEVSVMRRGE
                     MVATRTTADTSVEELAELMVGRRVLLQVDKGPASPGEVALSVEGLTVRDSRGVDMVKD
                     VSLQVRAGEIVGVAGVAGNGQSELLEAITGIRRGVSGRVLLQGQPIHVTGEADPAELR
                     HRGLAHVPEDRQHMGLVLKFDESENSILGYHDDGKYLNGVFLNTDAIREDAVAKIEKY
                     DIRPPNPRLKTANFSGGNQQKIVLAREMERDPPVLVIGQPTRGVDVGAIEFIHKRIIE
                     MRDAGKAVLLVSVELDEIRSLADRILVMFDGRIVGERSPETSEGELGLLMAGVEDTKE
                     AAE"
     gene            295297..296430
                     /locus_tag="HPDFL43_19392"
     CDS             295297..296430
                     /locus_tag="HPDFL43_19392"
                     /note="COG4603 ABC-type uncharacterized transport system,
                     permease component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transport system permease abc
                     transporter protein"
                     /protein_id="ZP_02164696.1"
                     /db_xref="GI:163757607"
                     /translation="MSAPYAKLPAWVDYGLIPLINLVVAFMVAGLVVLAVGESPLRAA
                     SLLIQGAFGYGEGIGFTLYYATNFIFTGLAVAVAFHCGLFNIGGEGQAYVAGLGVALP
                     ILWLDQIMPWYVVFPAAILGSALVGAAWAFIPGWLQAKRGSHVVITTIMFNFIASSLM
                     VYVLVDVLKPAGSMAPQTRTFEEGGQLPRLDWLLSPFGLDIGGAPFNLSFLLALVAAF
                     VVWVVIWRTRLGYEIRTMGHSPKAARYAGIKESRIIIITMMMSGALAGMMALNPIMGD
                     QHRMQLDFVTGAGFVGIAVALMGRSHPVGIVPAAILFGVLYQGGAEISFEMPQISRDM
                     ITIIQGLVILFAGALENMFRPAITTFFATLGSAGETKTAPAAE"
     gene            296438..297409
                     /locus_tag="HPDFL43_19397"
     CDS             296438..297409
                     /locus_tag="HPDFL43_19397"
                     /note="COG1079 Uncharacterized ABC-type transport system,
                     permease component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transport system permease abc
                     transporter protein"
                     /protein_id="ZP_02164697.1"
                     /db_xref="GI:163757608"
                     /translation="METFDTLIVILQSTVRVSVPLILAALAGLYSERAGIFDIGLEGK
                     MLAAAFAGGAAAAVTASALMGLAAAIFVSVCLALVHAFASITQRGNQIVSGVAINFIA
                     LGATVILGQAWFQQGGRTPQLVEGARFSTVELPFAAEIANVPILGSIYSNLLSGHFLL
                     TYLAFALVPFTWWVLYRTRFGLRLRAVGENPGAVDTAGISVTWMRYRAVICCGILCGI
                     AGAYLSMAMTAGFVKGMTAGKGFIALAALIFAKWKPVNVMFACLLFGFLDAMSIRMQG
                     NALPLIGEVPVQLMQALPYILTVVLLAGFIGKAIPPKAGGVPYVKER"
     gene            297411..297803
                     /locus_tag="HPDFL43_19402"
     CDS             297411..297803
                     /locus_tag="HPDFL43_19402"
                     /note="COG0295 Cytidine deaminase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative cytidine deaminase (cytidine
                     aminohydrolase)"
                     /protein_id="ZP_02164698.1"
                     /db_xref="GI:163757609"
                     /translation="MSQDLFEAARDAMALCHAPYSKFPVGAAIRAEDGAIYAGANIEV
                     LSFPEGWCAETTAIGHMIMAGARRIREVAVIAEKLELCPPCGGCRQRLAEFADPDTLI
                     HLCDAQGVKQTLRMDELLPFGFKTEVIG"
     gene            297800..298597
                     /locus_tag="HPDFL43_19407"
     CDS             297800..298597
                     /locus_tag="HPDFL43_19407"
                     /EC_number="2.4.2.1"
                     /note="COG0005 Purine nucleoside phosphorylase"
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphorylase"
                     /protein_id="ZP_02164699.1"
                     /db_xref="GI:163757610"
                     /translation="MKSVTDILTDRLRGLLPRHAMILGSGLGSLVETVTDPVRIPYGD
                     LPGFPVSGVSGHAGEVVAGLIGNTPVMMLSGRAHYYEHARADAMRPPLEALQGIGVTN
                     LILTNAAGSLREDMPPGSVMRITDHINFSGSNPLFGEPSDRRFVGLTNAYDVDFGARM
                     KAAAEATGTPLHEGVYMWFSGPSFETPAEIRMARIIGADAVGMSTVPEVILARFLGMK
                     VAAASVITNYAAGMTGGELSHQETKDMAPVGGKRLAAILTHALGGEA"
     gene            298594..299619
                     /locus_tag="HPDFL43_19412"
     CDS             298594..299619
                     /locus_tag="HPDFL43_19412"
                     /note="COG0274 Deoxyribose-phosphate aldolase"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose phosphate aldolase"
                     /protein_id="ZP_02164700.1"
                     /db_xref="GI:163757611"
                     /translation="MTNKTAALAATGRQETGSQLVSLAPAHKRNMGTEFLPAMFENMS
                     VNLSATERRIATLGARRTVKKNWQAAWLIRAIECIDLTTLAGDDTPGKVERLCAKARN
                     PLRADLRKALGLDDYALTTGAVCVYPMMVSTAVRALEGSGVPVASVATGFPAGLTPMK
                     DRLAEITYAVGEGAEEIDIVISRRHVLTGNWSALYDEVRRMREACGEAHMKAILSTGE
                     LKTLSNVYKASMVSMMAGADFVKTSTGMEAVNATLPVSLTMVRSVRDYFEFTGQICGF
                     KPAGGIRTSKDAIAWLVLMKEELGNDWIKPDLFRFGASALLGDIERQIEHHVTGRYAS
                     SDRHGMA"
     gene            299630..302020
                     /locus_tag="HPDFL43_19417"
     CDS             299630..302020
                     /locus_tag="HPDFL43_19417"
                     /note="COG1012 NAD-dependent aldehyde dehydrogenases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164701.1"
                     /db_xref="GI:163757612"
                     /translation="MNEIRDILNTMDYGPAPEDDKEVRAWLANHKDGFGHFIGGSFTK
                     LGGNTFEVHNPANGETLARVAIANAEDVDRAVGEAAKAQKKWQALSGNKRARHVYALA
                     RHIQKHARFLAVLETLDNGKTIRETRDIDIPLVARHFYHHAGWAELCETEFPGYEAAG
                     VCGQIIPWNFPLLMLAWKVAPALAAGCTVVLKSAEHTPLTAIAFAEICTEAGLPAGVF
                     NLVNGAGETGAALAGHDGIAKLAFTGSTEVGRVLRRQTAGSGKKLSLELGGKSPFIVF
                     ENADIDAAVEGVVDAIWFNQGEVCCAGSRAIVQEGIADRFHDKLRARMEKLRVGNPLD
                     KSMDMGAVVAPVQIREITAKVEAGIAEGGSMWQPSWARTVSNADGCFFPPTLFTGVAP
                     SSTLAQEEIFGPVLASMTFRTPGEAVQLANNSRYGLAASVWSQNLDEAFDAARQIKSG
                     IVWINATNLFDASAGFGGYKESGFGREGGREGMREYLVPSWQKKAKLLPESEPLAAPV
                     PVPGGDAPGLDRTVKMYIAGKQARPDSGYSYPVTGKNGRHLAEVGLGSRKDIRNAVEA
                     AHKASAWSAMTGHQRAQVLYFLAENLELRSAEFAARLADAGASASAAKREVEASVARI
                     MHYAAWADKYDGAVRAPDKRMLTLALNEPWDVMGISCPDEAPLLAFVSLVLPAIAMGN
                     RVVVTPSPRQPLPALDFYQVLDTSDVPGGVVNIVTGDRDTLADTMAKHDDIAALWYFG
                     GQAGTALVERESAGNLKPVWASNGKARNWSDPVQGQGEEFLFRAVRIKTIWTPFGV"
     gene            302030..303340
                     /locus_tag="HPDFL43_19422"
     CDS             302030..303340
                     /locus_tag="HPDFL43_19422"
                     /note="COG0213 Thymidine phosphorylase"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="ZP_02164702.1"
                     /db_xref="GI:163757613"
                     /translation="MLPQEIVRTKRDGGELDREQIAAFITGLTDGSVSEGQVAALAMA
                     VFFNGMTRAEAVALTLAMRDSGEVLSWPELDRPVVDKHSTGGVGDNVSLMLAPIAAAC
                     GLAVPMISGRGLGHTGGTLDKMEAIPGYQAMPDNALFRKVVASAGCAIIGQTGNLAPA
                     DKRFYGIRDVTATVESVPLITASILSKKLAAGLGALVLDVKCGNGAFMDNPVRAAELA
                     RSLVEVATGAGMPTTALITDMNQPLASAAGNAVEVQNAADFLTGDARDPRLEAVTVAL
                     AAEMLVSGGLASDPEAGAVQARRALEQGYAAEHFNRMVAALGGPTDFLADPARHLAKA
                     PIVADCLAEAEGFVTGYDTRGIGLAVVELGGGRVRPSDPVDHAVGLTDLLPVGTRLEK
                     NRPIARIHARTPDQVEQVQAQLKRAIRIGADLPQLDPVIVGREV"
     gene            complement(303353..303949)
                     /locus_tag="HPDFL43_19427"
     CDS             complement(303353..303949)
                     /locus_tag="HPDFL43_19427"
                     /note="COG3577 Predicted aspartyl protease"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164703.1"
                     /db_xref="GI:163757614"
                     /translation="MNVFNGTEISELCMFKKIFLISCAVLGIASLPHYAQDVSVFTGT
                     MSDKESSGVPVPEVKTASAHPAQPLAHYATGVRAATIPMDRSGHFSADFRVNGRNLKG
                     LIDTGATYVALNVSTARSLGLGLVGSDFKHQVNTANGKTSAALVMLDQMNVGSITVRN
                     VEAFVLEDKALSSTLIGMSFMSKLKSYQVKGNRLELVN"
     gene            complement(304063..304692)
                     /locus_tag="HPDFL43_19432"
     CDS             complement(304063..304692)
                     /locus_tag="HPDFL43_19432"
                     /note="COG0035 Uracil phosphoribosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative uracil phosphoribosyltransferase (UMP
                     pyrophosphorylase)"
                     /protein_id="ZP_02164704.1"
                     /db_xref="GI:163757615"
                     /translation="MDGVTVIDHPLVQHKLTIMRKKETSTAGFRRLLREISTLLCYEV
                     TRDLELTMERIETPLTEIEAPVLEGKKLVFASILRAGNGLLEGMLDLVPSARVAHVGV
                     YRDHETLEAIEYYFKAPEDVSNRLVIVVDPMLATGNSSIASIDKLKERGAHNIRFLCL
                     LAAPEGIRNFQAAHPDVPIFTASIDSHLNEKGYIVPGLGDAGDRMYGTK"
     gene            complement(304877..305848)
                     /locus_tag="HPDFL43_19437"
     CDS             complement(304877..305848)
                     /locus_tag="HPDFL43_19437"
                     /EC_number="3.5.4.4"
                     /note="COG1816 Adenosine deaminase"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="ZP_02164705.1"
                     /db_xref="GI:163757616"
                     /translation="MTLNVKKAELHCHIEGAASPALVKAQARKYGADVSTFIADDHYV
                     WSDFTEFLAAYDGAAALFRSEEDYALLARTYLEGIAAQNAIYAEIFVSPDHAAAAGLT
                     AEAYLNGLGEGIEAARSATGIECRMIIVGVRHLGAEKVEAAARLAATRPHSLITGFGM
                     AGEERFGRVADFTRAFDIARDAGLGITIHAGELAGPESVRDALDHVRPSRIGHGVRAS
                     EDPDLVRRLADEGVVLEVCPGSNLALNVYPDITSHPFDALRREGVKVTLSSDDPPHFH
                     SSIGHEYQLVADAWGYSSAEMTGFTKTSIEAAFVDEPTREILLGQLG"
     gene            complement(305845..307065)
                     /locus_tag="HPDFL43_19442"
     CDS             complement(305845..307065)
                     /locus_tag="HPDFL43_19442"
                     /note="COG1015 Phosphopentomutase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="ZP_02164706.1"
                     /db_xref="GI:163757617"
                     /translation="MARAFLFVLDSFGIGGAPDAEAYGDLGANTLGHIAEQCAAGLAD
                     RADLRKGPLALPHMQSLGLAEAALAASGELPAGWELAVRPRGLHGAAAEVSHGKDTPS
                     GHWEIAGQPVMFDWGYFPDDGAAFSDELIAAIASQGDVPGILGNCHASGTEIIASLGA
                     EHMRTGKPICYTSSDSVFQIAAHEESFGLDRLIKLCQTVRSLVDPLNIGRVIARPFVG
                     TPETGFDRTGNRRDFSVPPPGPTLLDQISDNGNRVFAVGKISDIFAHQGVTDLRKANG
                     NAALFEATLKAAKDAKDGDLVFTNFVDFDMLYGHRRDVPGYAAALEALDAKLPRFAKL
                     LKPGDLVLMTADHGCDPTWRGTDHTRERVPILGFGPGIAARSIGIRRSFSDIGATVAA
                     HLGLPPLANGRSFL"
     gene            307198..308127
                     /locus_tag="HPDFL43_19447"
     CDS             307198..308127
                     /locus_tag="HPDFL43_19447"
                     /note="COG3221 ABC-type phosphate/phosphonate transport
                     system, periplasmic component"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164707.1"
                     /db_xref="GI:163757618"
                     /translation="MIVTKPAAAMAVSFFATCRAGVAVLALGACAAFADYRDTVPVLR
                     IGVVENHVALTNPLKLEAVQQAFSKTLGIPIEIIRMRSYAALVDAHASGRVGYAIHSA
                     RSYAATDAACGCVIPFRTPVAADGSSGFRSVLAVGDSVTRPISELRIAYSNEDSVSGW
                     QIPHQAMQAGSLETPQLVRAGTVAATITLYGAGEADGFFGWVPDIATAAGSDPSLLFG
                     GWNRQMVLESDPVRVIWSSQRIPYGPHALHRSLPDDLLAALGAFLDQMPENEPGLLDI
                     FEPFFAGGYVTPGLKDYENLQGLVVAPPDGGDG"
     gene            complement(308136..308708)
                     /locus_tag="HPDFL43_19452"
     CDS             complement(308136..308708)
                     /locus_tag="HPDFL43_19452"
                     /note="COG4961 Flp pilus assembly protein TadG"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane protein"
                     /protein_id="ZP_02164708.1"
                     /db_xref="GI:163757619"
                     /translation="MTGALIGLMQTARRLRGNKDGVGAVEFALIAPVLIILYMGSLEI
                     SVAMSVNKKLARASSTVADLITQEESVDKVYLTSMVNVVESVMTPFRSEGVRVKVTGI
                     AINGAGNATASWSWQDNGSRPYSAGSTQTLPADLAIPNTFLVRTEVEFDHKLLLVLPG
                     VSDIDIRTLKMAKTYHLRQRMGNSVTCSNC"
     gene            complement(308705..309223)
                     /locus_tag="HPDFL43_19457"
     CDS             complement(308705..309223)
                     /locus_tag="HPDFL43_19457"
                     /note="COG1239 Mg-chelatase subunit ChlI"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane protein"
                     /protein_id="ZP_02164709.1"
                     /db_xref="GI:163757620"
                     /translation="MLSLPFFMLVFATIEVFVAFAGEQLLENAVDTMSRQVRTGQITF
                     QMGRATDKTEAEFRAQLCEEISLMITCPENEDPNDQKLYLDVREFASFAAIPNDIPRV
                     GEAKHSDIDPSSFDYDPGGPGTINIVRAYYRWEVMTDLVRPFITNIRKDGEMPRDYLM
                     VATSAFRNEEYP"
     gene            complement(309465..309875)
                     /locus_tag="HPDFL43_19462"
     CDS             complement(309465..309875)
                     /locus_tag="HPDFL43_19462"
                     /note="COG4964 Flp pilus assembly protein, secretin CpaC"
                     /codon_start=1
                     /transl_table=11
                     /product="putative pilus subunit transmembrane protein"
                     /protein_id="ZP_02164710.1"
                     /db_xref="GI:163757621"
                     /translation="MTHSTPVRRRLAIAAFGMAIAVLSPLTAVADEDLIRVFMDHARI
                     LKLDRTVSKVIIGNAAVADVTVSDPRTIVLTGKSYGTTNLVILDQEGEAIVDERILVS
                     VDEANTLRVFKQTARSVYSCSPSCEEHKPGAVSP"
     gene            310210..310401
                     /locus_tag="HPDFL43_19467"
     CDS             310210..310401
                     /locus_tag="HPDFL43_19467"
                     /note="COG3847 Flp pilus assembly protein, pilin Flp"
                     /codon_start=1
                     /transl_table=11
                     /product="component of type IV pilus, pilin subunit
                     protein"
                     /protein_id="ZP_02164711.1"
                     /db_xref="GI:163757622"
                     /translation="MKEYPMKTIFDRFVKDESGATAIEYGLIAALISVALITGATTLG
                     NSLNNQFSGLATKLDNAGK"
     gene            310520..310882
                     /locus_tag="HPDFL43_19472"
     CDS             310520..310882
                     /locus_tag="HPDFL43_19472"
                     /note="COG3847 Flp pilus assembly protein, pilin Flp"
                     /codon_start=1
                     /transl_table=11
                     /product="component of type IV pilus, pilin subunit
                     protein"
                     /protein_id="ZP_02164712.1"
                     /db_xref="GI:163757623"
                     /translation="MDQAELRINVNESLIYFGHDEIGFSVAPIVCFSETASFIATSYK
                     FEGLASLFIWIKERSVLKFFECFAKDKTGTTAIEYGLIGTLISVSIIAGAMTLGNTVG
                     NQFQGLADKMNNAQNAHK"
     gene            complement(310980..311135)
                     /locus_tag="HPDFL43_19477"
     CDS             complement(310980..311135)
                     /locus_tag="HPDFL43_19477"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164713.1"
                     /db_xref="GI:163757624"
                     /translation="MKIAASTIEKLQDSLSTVMTATRVGFPGLRQPRAKGQVPLSEEV
                     SSAGVLI"
     gene            311185..311628
                     /locus_tag="HPDFL43_19482"
     CDS             311185..311628
                     /locus_tag="HPDFL43_19482"
                     /note="COG4960 Flp pilus assembly protein, protease CpaA"
                     /codon_start=1
                     /transl_table=11
                     /product="putative pilus assembly transmembrane protein"
                     /protein_id="ZP_02164714.1"
                     /db_xref="GI:163757625"
                     /translation="MKIPNRVSIVLGLSFFVVAPLSGMDLATFGWSIVAALIVFAVCF
                     ALFAVNVMGGGDAKILSAAALWYGFSSDLVVFLGFTGIYGGLLALVVLMLRANQNILL
                     VSPVPIPMHFFKDRAGIPYGVAIGAAAFSTYPDSRIFIEAIGRLH"
     gene            311829..312638
                     /locus_tag="HPDFL43_19487"
     CDS             311829..312638
                     /locus_tag="HPDFL43_19487"
                     /note="COG3745 Flp pilus assembly protein CpaB"
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein"
                     /protein_id="ZP_02164715.1"
                     /db_xref="GI:163757626"
                     /translation="MKPARVVIMAVAVLAAGLAGYLAMNLTAPTVQVNEISATPVIEK
                     MPTLDVLVVSASLPVGARLNEETMEWKGWPEDAVTEGLIRRESRPDAITELTGSIVRL
                     PLFTGEPLRPEKIVDSSSRIMSSLLPAGKRAIATEISVATSAGGFILPNDRVDVIMVR
                     RKTEQEGFLTEVILSNIRVLAIDQRIEEDAQGNRTAVGTTATLELTPDQSKIITVAQQ
                     MADRLTLALRSVADVQEPDTDGAKHLLSGEDGTSAIQLIRSGAITNVGATN"
     gene            312647..314137
                     /locus_tag="HPDFL43_19492"
     CDS             312647..314137
                     /locus_tag="HPDFL43_19492"
                     /note="COG4964 Flp pilus assembly protein, secretin CpaC"
                     /codon_start=1
                     /transl_table=11
                     /product="putative pilus assembly transmembrane protein"
                     /protein_id="ZP_02164716.1"
                     /db_xref="GI:163757627"
                     /translation="MNVRHIAKSLLSSIAGIALVGSVLVTGVLVDPTTGRLATPAQAS
                     QNIIKIKKSGPGVSKRVKLGLNKAIVVDLPTDAHDILVADPALADAVTRTSRRLYLFG
                     KTVGQTNIFVFGPNGEEIIAIELEIERDVAGLEVHLARFLPDSNIQVEIISDNIVLTG
                     SVRTPQDASQAARLAEIFLTGGEATTRVTTATSEGGDAAINAEDRQKSKIVNLLKIDG
                     EDQVTLKVTIAEVSRQVLKQLGFNTTISGDGSSSFGNSPSPWLSVPGLASVGSVAGTI
                     SGARISADISALERAGVIRTLAEPSLTAISGEVARFSVGGSFEIESERDEDGTIFEEK
                     EYGIKLEFTPVVLAPGRISLRIKTEVSEPTFEGQSPLPSIQKREAETSVELPSGGSMV
                     LAGLVRDSYRQTISGMPGASKIPVLGSLFRSKEFLRNETELVIIATPYLVKPVARNEL
                     SRPDDNFNAPSDGAGFFLGRVNRVYGQMETGLPAGRYHGAVGFIYK"
     gene            314152..314853
                     /locus_tag="HPDFL43_19497"
     CDS             314152..314853
                     /locus_tag="HPDFL43_19497"
                     /codon_start=1
                     /transl_table=11
                     /product="components of type IV pilus"
                     /protein_id="ZP_02164717.1"
                     /db_xref="GI:163757628"
                     /translation="MLSKISVPATPDLPRVRYLAISMLAAASVLTGCAGWGGKSVVVG
                     AVPDDYRTNHPIIVAEQERTVDIPVGTGDRELTTSMREIVRGAAHSYRSSASGAVRIM
                     VPVGSANAGAASILSGQVAKILQKEGVPRDRILSSPYSVSSPDDAAPIRIAYLAITAS
                     TEKCGRWPEDLAADTTENKHWANFGCASQSNLAAQIANPGDLIAPRGMSPIDAERRST
                     IIETYRESGAGLGAL"
     gene            314897..316183
                     /locus_tag="HPDFL43_19502"
     CDS             314897..316183
                     /locus_tag="HPDFL43_19502"
                     /note="COG0784 FOG: CheY-like receiver"
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein, response regulator
                     protein"
                     /protein_id="ZP_02164718.1"
                     /db_xref="GI:163757629"
                     /translation="MTELDYSLEQSEPAETVEVETARGDFDRIRPLPRISVHAFYETE
                     GLAKTMERCGEDRRMAKVNLRVNSGGVSAATNMFASSPTPNLLILETNADGATLIAEL
                     GELANYCDPDTRVVVIGHVNDVSLYRELVRNGVSEYIVAPVSMADVIGVVSSIFVDPE
                     AAPLGKSIAFVGAKGGVGSSTLAHNCAWSISSLFSSEVILADLDLAFGTANLNFDNDP
                     TQGIAEAVFSPDRLDEVFLDRLLAKCSEHLSMLAAPSMLDRTYDFSGDAFLPILEIVQ
                     RNAPVSVLDVPHIWSDWSRKILSAADEVVITATPDLANLRNTKNLFDTLRKLRPNDHP
                     PFLILNQVGMAKRPEIAPEVFCDPLEIEPLAIIPFDAPLFGEAANSGLMISESAAKSP
                     VAESFSQIAHVVTGRAEMKKRKKAGLASLMGMLGRK"
     gene            316209..317714
                     /locus_tag="HPDFL43_19507"
     CDS             316209..317714
                     /locus_tag="HPDFL43_19507"
                     /note="COG4962 Flp pilus assembly protein, ATPase CpaF"
                     /codon_start=1
                     /transl_table=11
                     /product="putative pilus assembly protein"
                     /protein_id="ZP_02164719.1"
                     /db_xref="GI:163757630"
                     /translation="MFGKRSNDGSVKAPMAPVPKPSVAAEAMATQPAAEAAPVAPIPA
                     TAQAPAAAPQPEPVASVRREEPPAKRKSARNEAYYDTKSQVFSALIDTIDLSQLAKLD
                     AESAREEIRDIVNDIITIKNFALSIAEQEELLDDICNDVLGYGPLEPLLARDDIADIM
                     VNGAGKTYIEVSGKVQETDVRFRDNGQLLSICQRIVSQVGRRVDESSPICDARLPDGS
                     RVNVIAPPLAIDGAALTIRKFKKDKLTLDQLVKFGAITPEGAVLLQIIGRVRCNVVIS
                     GGTGSGKTTLLNCLTAYIDTDERVITCEDSAELQLQQPHVVRLETRPPNIEGEGEITM
                     RDLVKNCLRMRPERIVVGEVRGPEVFDLLQAMNTGHDGSMGTIHANSPRECLSRMESM
                     IAMGGFTLPAKTVREIISGSVDVVIQATRLRDGSRRITHITEVVGMEGDVIITQDLMK
                     YEMVGEDANGKIIGEHRSTGIGRPHFWDRARYYGEDKRLAAALDAMEKMTS"
     gene            317727..318737
                     /locus_tag="HPDFL43_19512"
     CDS             317727..318737
                     /locus_tag="HPDFL43_19512"
                     /note="COG4965 Flp pilus assembly protein TadB"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164720.1"
                     /db_xref="GI:163757631"
                     /translation="MFGLDTVVVAIIGLAALSAGALGYGVLYSRIEGDRKAENRVKRV
                     KAAETDRSKASAARDRLAEANKRRKSVQDSLKTLDEKNKENDKKTSPPLKDKIGQAGL
                     PFSLGQFYMISLVLGLVAGLVGFVAYGSPLVAAGIAIIFGAGVPRWIVGYLRNRRLKA
                     FLSEFPNALDIMVRSIKSGLPLNDAIRMISAEGQEPVRTEFKRIVDSQQMGMNIPEAC
                     ARLYSRIPLSEANFFSIVIAIQAQAGGNLSEALGNLSRVLRDRKKMKAKINALSMEAK
                     ASAAIIGALPFIVALLVYLTSPDYIMILFTDTRGHLILGASAIWMSIGILVMRNMINF
                     DI"
     gene            318750..319745
                     /locus_tag="HPDFL43_19517"
     CDS             318750..319745
                     /locus_tag="HPDFL43_19517"
                     /note="COG2064 Flp pilus assembly protein TadC"
                     /codon_start=1
                     /transl_table=11
                     /product="putative component of pilus protein"
                     /protein_id="ZP_02164721.1"
                     /db_xref="GI:163757632"
                     /translation="MLSDIASSLTDPAYLVPILVSVAVFATLFTIMAPYFERGDLDKR
                     MKSAALERDEIRARERARLHAEQSRGGSKSAGLRAHNNASVRGIVEQLNLRKALADDA
                     TVAKLRAAGYRTQNALNMFLLARFVLPFFFFVAAVVYVFVLENMTDKPTTVRLLACIV
                     AAYAGFYAPNIFISNQSKKRQQSIKMAWPDALDLLLICVESGVSIEAAMKRVAEEIAI
                     QSTALAEEFLLTTAELSYLQDRRVAFENLGNRTGLEAVKSVTQALIQSERYGTPIAQA
                     LRVLAQESRDARMTEAEKKAAALPPKLTVPMILFFLPVLIGVILGPAAIQVMDRF"
     gene            complement(320068..320883)
                     /locus_tag="HPDFL43_19522"
     CDS             complement(320068..320883)
                     /locus_tag="HPDFL43_19522"
                     /note="COG5010 Flp pilus assembly protein TadD, contains
                     TPR repeats"
                     /codon_start=1
                     /transl_table=11
                     /product="putative pilus assembly protein (contains TPR
                     repeats)"
                     /protein_id="ZP_02164722.1"
                     /db_xref="GI:163757633"
                     /translation="MLKPGIRSNFSRRLFTAVCVAAIGISLAGCASKGKLTTGSIPSM
                     NKPLESMNAAELHSAAEQVGRAYDRNPKDPAIGMHYASVLTMGGRSSQALAVMQQVAI
                     HNPTDRTVLAAYGKALAGGGQFDKALDAIRRAQTPDRPDWQLLSAEGAILDQMGDPAG
                     ARNRYRKALDIKPNEPSILSNLGMSYLLQGDLRTAETYLASAVQQPGADSRVRQNLAL
                     VVGLQGRFGEAEKIASAELSPEQAQANVTYLRSMLSQQNAWNKLKDNDRKNTN"
     gene            321044..322438
                     /locus_tag="HPDFL43_19527"
     CDS             321044..322438
                     /locus_tag="HPDFL43_19527"
                     /note="COG0260 Leucyl aminopeptidase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminopeptidase protein"
                     /protein_id="ZP_02164723.1"
                     /db_xref="GI:163757634"
                     /translation="MPPYQFIERPSPFAPMSSASLPVWAISRADLERGQFDKTALAWA
                     TSAGFNAAEGSLLLAPSRHGKLAGALFGLGDETECNPFIGGKLARALPAGDWHIETSP
                     ISGAVMALAFGMGAYRYESYRKPAPAGPRLVIPADADADTITRTVAAVSLARDLVNTP
                     ANDMGPDALETVFLALAKRYKAKTKVVTGDALLSANFPMIHAVGRAAEQAPRLLEMRW
                     GKKGAPKLTLVGKGVCFDTGGLDIKPASSMLLMKKDMGGAANVLALAMMIMDAGLAVD
                     LRVLIPAVENSISASAFRPGDVLTSRKGLTVQIDNTDAEGRLVLADALSYACEDKPAL
                     IVDMATLTGAARVALGPDLPPFYTDDETLAGSLSESSRAVADPMWRMPLYKPYEADVK
                     ARIADLTNAPSGGFAGSITAALFLKRFIEPEVSWVHFDIFAWSPKERPHGPVGGEAQA
                     IRALFDVVSQRYPA"
     gene            322514..322882
                     /locus_tag="HPDFL43_19532"
     CDS             322514..322882
                     /locus_tag="HPDFL43_19532"
                     /note="COG1846 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcription regulator protein"
                     /protein_id="ZP_02164724.1"
                     /db_xref="GI:163757635"
                     /translation="MSVDLRPSEALGLWHAATLEHVRLIGPDLTIRQLAILLHIYLAA
                     PPHTVRGLAAMLGVTKPVITRALDTMGHMGLVRRVRDERDRRNVVIKRTVEGSLFVER
                     LGDIIITEGRKLTAAEPKTP"
     gene            322879..323739
                     /locus_tag="HPDFL43_19537"
     CDS             322879..323739
                     /locus_tag="HPDFL43_19537"
                     /note="COG0791 Cell wall-associated hydrolases
                     (invasion-associated proteins)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164725.1"
                     /db_xref="GI:163757636"
                     /translation="MTETLDRRLHAYRPDLADIRLREKVSAGRYTQGMAAEVAVPLAK
                     LHPKPDPDCAIDTEALFGETLQVFDRRDGWAWVQLDADGYVGYLREEALGDRSSEATH
                     LVCVPRTFVYSGADLRFPVVHALSMASRVRVTGMTETRGTIYALMGDGPAMIAEHLRP
                     LAEAASHDAVAVAAMFLQTPYLWGGRSGFGIDCSGLVQMALAMTGKPAPRDSDQQASG
                     LGQAIDPVQHGLRRGDLVFWKGHVGFLEDPHTLLHASGGTMSVTREPLKAAIERIAKL
                     YGHPTGYRRP"
     gene            complement(323769..324734)
                     /locus_tag="HPDFL43_19542"
     CDS             complement(323769..324734)
                     /locus_tag="HPDFL43_19542"
                     /note="COG0111 Phosphoglycerate dehydrogenase and related
                     dehydrogenases"
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="ZP_02164726.1"
                     /db_xref="GI:163757637"
                     /translation="MNTTAAKGHILLSLTGWDPSIWVKELSQAAPERPVKLAPDGETD
                     PDIEYAVVWKPEASALAKLPRLKAIFSLGAGVDHVFATPGLPDVPIVRVVSPDLTTRM
                     SEYVVWQVLDHQRLGPKYRAQQAARIWEEDRGQCAAGDITVGIMGIGELGMDAAHKLR
                     CLGFDVSGWSRTPKQVEGIICYAGREGLGEFLASADIFVVLLPLTPDTRNILDKDLFA
                     RMTKRGPLGAPVLINAGRGGLQNEADILSALDQGLLSAVTLDVFHEEPLPPESPFWGH
                     PKVTLTPHAAAASVPSSLIRPMVAQMNAYDRGEPLINLVDRKAGY"
     gene            complement(324742..326409)
                     /locus_tag="HPDFL43_19547"
     CDS             complement(324742..326409)
                     /locus_tag="HPDFL43_19547"
                     /note="COG4172 ABC-type uncharacterized transport system,
                     duplicated ATPase component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative atp-binding abc transporter protein"
                     /protein_id="ZP_02164727.1"
                     /db_xref="GI:163757638"
                     /translation="MNRMAQPAKAADNTSEPLLSVRDLSVAFHQGGDSQMAVDRISFD
                     IKRGETVALVGESGSGKSVSALSVLKLLPYPAASHPSGKILFKGEDLLSAPEAAIRDV
                     RGNAITMIFQEPMTSLNPLQTVEKQISEILHLHQPISADEARKQVLELLDQVGIRDPR
                     QRLNSYPHQLSGGQRQRVMIAMALANRPELLIADEPTTALDVTVQAQILELLRDLKTS
                     HGMAMLFITHDLGIVRKFADRVCVMTKGEIVESGPTSEIFANPQHAYTKHLLAAEPKG
                     EPPYRAENAPQVMRADDIKVWFPVKQGFLRRTVDHIKAVDGLSLTLKAGQTLGVVGES
                     GSGKTTLGLALMRLIRSEGQIFFEDKPLHELSFKQMKPLRSAMQVVFQDPFGSLSPRM
                     SIADIVGEGLAIHAKGLSAKERDRQVANALEEVGLDAATRWRYPHEFSGGQRQRIAIA
                     RAMVLKPRFVMLDEPTSALDMSVQAQVVDLLRDLQARHDLAYLFISHDLKVVRALAND
                     VIVMRAGKVVEQGIADQIFDQPKTDYTKALMAAAFNLETADSGVVSE"
     gene            complement(326406..327557)
                     /locus_tag="HPDFL43_19552"
     CDS             complement(326406..327557)
                     /locus_tag="HPDFL43_19552"
                     /note="COG4239 ABC-type uncharacterized transport system,
                     permease component"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter, membrane spanning protein
                     (peptide)"
                     /protein_id="ZP_02164728.1"
                     /db_xref="GI:163757639"
                     /translation="MNAPASATSQSYDAKGRPKGWLSPTNRRRWANFKANRRGYWSLW
                     IFMILFIASLLGEFIANDRPILASYKGEILYPVLIDYPEEKFGGFLARTDYRDPFIQE
                     EIEANGWMIWPPIRYSYTTANSYIPHSAPTAPFWLMDKETRCQAYPLKHEDPGCRLGN
                     MNWLGTDDQARDVTARMIYGFRISVLFGLTLTILSALIGVAAGAVQGYFGGWTDLLMQ
                     RFIEIWSSMPVLYILLIIAAVLPPGFWILLGIMLLFSWVSFVGIVRAEFLRARNFEYV
                     NAARALGVGNGTIMFRHLLPNAMVATLTFLPFILSGSITTLTSLDFLGFGLPPGSASL
                     GEMIAQGKRNLDAPWLGLTAFFTISIMLSLLIFIGEATRDAFDPRKTFR"
     gene            complement(327554..328657)
                     /locus_tag="HPDFL43_19557"
     CDS             complement(327554..328657)
                     /locus_tag="HPDFL43_19557"
                     /note="COG4174 ABC-type uncharacterized transport system,
                     permease component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative permease abc transporter protein"
                     /protein_id="ZP_02164729.1"
                     /db_xref="GI:163757640"
                     /translation="MGVYILRRLLLMVPTIIGIMAISFAVIQFAPGGPVEQVIAQLTG
                     QGDSAADRISGGGGDQGFETQQFGDDVTSQYRGAQGLDPEFIAKLEAQFGFDKPPLER
                     FGLMMWNYIRFDFGESYFRSIDVIDLIAEKLPVSISLGVWILLLSYIISIPLGIKKAV
                     SDGSRFDVWTSGVIIVAYAVPGFLFGILLIVLFAGGSFYDLFPLRGLTSDNFSELSLF
                     GKIVDYFWHLTLPLIALSLSAFATTTLLTKNSFIDEIRKQYVTTARAKGLTERQVLYR
                     HVFRNAMLIIIAGFPGAFITAFFSGSLLIEYIFTLDGLGRLGFDSITKRDYPVVFATL
                     FIFSLMGLVVGLISDLIYTWVDPRIDFEKRDVG"
     gene            complement(328826..330679)
                     /locus_tag="HPDFL43_19562"
     CDS             complement(328826..330679)
                     /locus_tag="HPDFL43_19562"
                     /note="COG4166 ABC-type oligopeptide transport system,
                     periplasmic component"
                     /codon_start=1
                     /transl_table=11
                     /product="putative periplasmic binding protein"
                     /protein_id="ZP_02164730.1"
                     /db_xref="GI:163757641"
                     /translation="MEMVSRGYASMINRFSPLLATLAALMMTMPPGLSAEPVWRHATA
                     LVGEAKYPERFERFDYVNPEAPKGGTLKLSSSGSFDTLNPIPAKGDLAVGLDLVFETL
                     MTSSEDEISSNYGLLAEAVRYPDDYSWVSYRLREGARWHDGEPVTVEDVVWSFEQTVA
                     NNPQREFYYRHVTKAEATGPREITFTFDEKNNKELPKIVGELIILPKHWWESESGEPR
                     SIDETTLQPVLGSGPYRIANVRPGDIMTFERVEDYWGADLNVNVGQNNFDQIEYTYFG
                     DRNVEFEAFKSGNVDFWQENEAKRWANAYNFPAMEEGRITREEPENLYRSSGILVGFI
                     PNLRREKFSDPRVRQALNLAYDFEEQNRTLFFGQYERINSFYYGTELASSGLPQGQEL
                     EILERLRDKIPESVFTTPYENPVAGDPTKLRANFRKAVSLFQEAGYTLRGNQMVNAET
                     GEPFTFEIILNGPIIEKVALPYAQNLKRIGVAVSVRVLDSSQYTNRLRARDFDMIYFG
                     WGQTLAPGNEQAEFWGSKAAAREGSANYAGIADPAVDELVREVAFAKDRTTLIDTVRA
                     LDRVLLANHFVIPTYTLRKSRLAYWNRITRPEELPYYGLGFPAVWWFEGDE"
     gene            complement(330810..331364)
                     /locus_tag="HPDFL43_19567"
     CDS             complement(330810..331364)
                     /locus_tag="HPDFL43_19567"
                     /note="COG3474 Cytochrome c2"
                     /codon_start=1
                     /transl_table=11
                     /product="putative cytochrome c transmembrane protein"
                     /protein_id="ZP_02164731.1"
                     /db_xref="GI:163757642"
                     /translation="MNSSYFNSGAGAFLGIVFVLMTLSIVSDGIYHAAKPETEGFAIE
                     VAEASTDTSEPAEEAAPELVEPLLASADPAKGEGVFKKCAACHTNDAGNGNKVGPGLW
                     NIINRPVAQHADFKYSTALVDYSEGGAVAWTYERLSNFLAAPKKYISGTTMGFAGLKK
                     IDDRANLLAYLRTVADTPPPLPGE"
     gene            331536..332282
                     /locus_tag="HPDFL43_19572"
     CDS             331536..332282
                     /locus_tag="HPDFL43_19572"
                     /note="COG1212 CMP-2-keto-3-deoxyoctulosonic acid
                     synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase
                     (CMP-KDO synthetase) (CMP-2-keto-3-deoxyoctulosonic acid"
                     /protein_id="ZP_02164732.1"
                     /db_xref="GI:163757643"
                     /translation="MKQDQEPMLVIIPARMAASRLPGKPLADINGVPMIVRVARQAER
                     AGVGPVAVATDAREIADVVEAAGLVAVMTRDDHQSGSDRVFEAAMKLDPEGKSDVILN
                     IQGDIPAIEPETIRRSALPLTLSSAELATIAVQITDEDEKTNPSIVKVIGTPVGNDIL
                     RALYFTRATAPYGDGPLYHHIGLYAWRRSALKRFVSLKQSTLEKRESLEQLRALEDGM
                     RIDVAIVDSVPLGVDTPADLERARQIIAAG"
     gene            332311..333195
                     /locus_tag="HPDFL43_19577"
     CDS             332311..333195
                     /locus_tag="HPDFL43_19577"
                     /EC_number="4.2.1.51"
                     /note="COG0077 Prephenate dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="ZP_02164733.1"
                     /db_xref="GI:163757644"
                     /translation="MTYSTNRIAIQGEFGANSDMACRDMFPALEPLPCPTFEDAFNAL
                     AQGEADLAMIPIENTIAGRVADIHHLLPESQLHIIGEYFMPIHFQLMVLPGTKLSDIK
                     TVHSHVHALGQCRKIVRANGWKAIVAGDTAGAAKLVSNSGDKTMAAFAPKLAADLYGL
                     DILAENVEDTETNVTRFVVLSRDAKTPPRPVADEVVVTTFVFRVRNIPAALYKAMGGF
                     ATNGINMTKLESYQIGGKFFATQFYADIQGHPDEAPVARAMEELGFFSKELRILGVYP
                     AHPFRLAQNGSHAEDAEG"
     gene            complement(333204..334166)
                     /locus_tag="HPDFL43_19582"
     CDS             complement(333204..334166)
                     /locus_tag="HPDFL43_19582"
                     /note="COG2816 NTP pyrophosphohydrolases containing a
                     Zn-finger, probably nucleic-acid-binding"
                     /codon_start=1
                     /transl_table=11
                     /product="putative MutT/nudix family protein"
                     /protein_id="ZP_02164734.1"
                     /db_xref="GI:163757645"
                     /translation="MSVSLFEHNAPHGEASRLVAFSTNRLDRRSEHRNESELGEALSD
                     PRTRYFGITQGRLAMRVNGDTPEGLLSAGDLSTLKPEHKNAILIGWDADNAAHIAVPL
                     EMAADDLPDPFKAIDTRSVYRQALLNEETLGAYAQGNSLVAWALANRFCGCCGSAMTP
                     ESGGYRRKCQACGHTVFPRTDPVAIMLAVDETRDRCLLGRSPHFPPGMYSCLAGFIEP
                     GETMEDAVRRETLEESGIQIGRVRYHASQPWPMPHSLMIGVYAEAKSLDITRDTNELE
                     DCRWFDRSETEAMLADVLGETDASAPPPGAIAHRLMRDWLDWGR"
     gene            complement(334227..334631)
                     /locus_tag="HPDFL43_19587"
     CDS             complement(334227..334631)
                     /locus_tag="HPDFL43_19587"
                     /note="COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase
                     and other HIT family hydrolases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164735.1"
                     /db_xref="GI:163757646"
                     /translation="MAGFSLDERLAKDTTLLMKLGLCQLRLMHDSRWPWVLLVPQRAG
                     ISEIFDLTPLDQTMLTFETSIAAKAVKQATDCHKINVGALGNQVRQFHLHIIARNETD
                     PAWPWPVWGHGTALPWEAGAQAEFTNRLLQAL"
     gene            334931..336850
                     /locus_tag="HPDFL43_19592"
     CDS             334931..336850
                     /locus_tag="HPDFL43_19592"
                     /EC_number="2.7.7.7"
                     /note="COG2812 DNA polymerase III, gamma/tau subunits"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunits gamma and tau"
                     /protein_id="ZP_02164736.1"
                     /db_xref="GI:163757647"
                     /translation="MDGTDRLGQHEGGTKIMDDTTSANPAGPAASQATPGAEQTPYRV
                     LARKYRPKDFTDLIGQEPMVRTLTNAFSTGRIAQAWMLTGVRGVGKTTTARILARALN
                     YKTAEIDQPSIDLTTPGEHCPAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVS
                     ARYKVYIIDEVHMLSTQAFNGLLKTLEEPPAHVKFIFATTEIRKVPITVLSRCQRFDL
                     RRIETGALASHFSSVAAQEGIGIDDESLSMIARAAEGSVRDGLSLLDQAIAHGGGQVD
                     AQAVRAMLGLADRSRVVELFGNLMAGDVAAALTGFRDQYDSGAGPSVILTDLADFTHL
                     VTRLKFVPEAADDPSLTETERERGADYAGKLSTAILSRVWQMLLKGISETEGSSRPAA
                     AAEMALIRIAHAASLPSPEEALKAFQNGGGSSGAGVAQTTAGGSHGGSAGSSSGGDAM
                     ARAVGERHMPQTGNGQPSMRLAHSAEPSVAPPAAEPVEQVAVASLEDMVVLAEKHRDI
                     AMKVQIRTGVRLVRIEQTRLEISLAPDASPSLPGELVKKLKDWTGANWSVALSREEGA
                     PTITEREAAKRDALVSDARQDPDVAAILSKFPGSKITDVRIAATEEELAGAALSPSED
                     GDILPAETEPDDNSD"
     gene            336905..337228
                     /locus_tag="HPDFL43_19597"
     CDS             336905..337228
                     /locus_tag="HPDFL43_19597"
                     /note="COG0718 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164737.1"
                     /db_xref="GI:163757648"
                     /translation="MKDIMGMMGKIKDMQAKMESMQEEIATMECEGVSGGGMVTVKLS
                     GKGQMLGLKIDPSMFKEDDVEILEDLIIAAHNDAKVKAETMMAERTKELTAGLPIPPG
                     MKLPF"
     gene            337255..337860
                     /locus_tag="HPDFL43_19602"
     CDS             337255..337860
                     /locus_tag="HPDFL43_19602"
                     /note="COG0353 Recombinational DNA repair protein (RecF
                     pathway)"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein"
                     /protein_id="ZP_02164738.1"
                     /db_xref="GI:163757649"
                     /translation="MQKRVTGPEIERLIQLLARVPGLGPRSARRAALHLIKKKDQLMG
                     PLALAMNEAHDKVQICSTCGNADTVDPCTVCTDPARDQSVIIVVEDVADLWALERAAA
                     MNAGYHVLGGTLSPLDGVGPDDLSIAGLVDRVARGGVREILIAVNATVEGQTTAHYIT
                     EQLSGFDLKVTRLAHGVPVGGELDYLDEGTLAAAIRARTAF"
     gene            337869..338258
                     /locus_tag="HPDFL43_19607"
     CDS             337869..338258
                     /locus_tag="HPDFL43_19607"
                     /note="COG0251 Putative translation initiation inhibitor,
                     yjgF family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164739.1"
                     /db_xref="GI:163757650"
                     /translation="MTKFSNPGTMPMPASNYVQMVETTGPGRRLIISGQIGVAANGEV
                     SQGYEAQAEQAWRNALAGLEAAGMGLSDIIAIRVYDVAPGNVAAYRQIRDRMLQGHAP
                     ASTYVIVAGLASPDFLTEIEVEAFAVD"
     gene            338320..339567
                     /locus_tag="HPDFL43_19612"
     CDS             338320..339567
                     /locus_tag="HPDFL43_19612"
                     /note="COG2951 Membrane-bound lytic murein
                     transglycosylase B"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transglycosylase transmembrane protein"
                     /protein_id="ZP_02164740.1"
                     /db_xref="GI:163757651"
                     /translation="MIRTAVFAVLSLLVALCGVSPAWAATKAQVESQFARWLEADLWP
                     EARAKGVTKQVFDRAFNGVQLDWDLPDLAPPGFPKPKKRTQSQAEFRSPGAYFSEKRL
                     QSLAASGRSLMQKHQAVLRRIEDKYGVPASIIVAVWGRESGFGRAKIPHSAVGVLVTK
                     AFMSTRPDLFRTEILAALQILQRGDVSASAMRSSWAGAMGQPQFLPSSYLKFAVDFDG
                     DGKRDIWNSIPDSLASIGNYLAQSGWVRGRDWGFEAVIPQGTTCALEGPDRAMPIRDL
                     TAMGIIRISGRPFPEHERTAPGMVLVPAGIYGPEFVVTPNFYVIKEYNNSDLYALFIG
                     NLADRMAYGGGAFITPWGNVGGMLRSDIAKLQTVLERQGYDVGGADGLPGYKTRRSIG
                     EWQAKNGAQPTCFPTPQLLKGLN"
     gene            complement(339617..340603)
                     /locus_tag="HPDFL43_19617"
     CDS             complement(339617..340603)
                     /locus_tag="HPDFL43_19617"
                     /note="COG0500 SAM-dependent methyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164741.1"
                     /db_xref="GI:163757652"
                     /translation="MGRHLSASTSGAYGIEHRADFMNYSILSFFLPFTGYPYQGHEVA
                     CPGCGHENHTRIAGIDRRLKRLPTVACDFCGLIFTNPMPTDAELSTYYSDFYRFDYQA
                     ADTAPKEKHLRKRRLEAAGRVSQLEGLLPGTGRTLDFGCGSGEFVGAMLALGHDAHGF
                     EPGDTYGSHAKSLYGDRITVNGWQDVTYSDQFDLVTCFHVLEHLSNPVDALRQMAAWA
                     KPDGFVFIEVPDLGKTHPNKGFGALHFAHLLGFNQHNLIVAAAQAGLAPERIVAPTGI
                     IFRKGTTEAGSVEAEAAKGRALSEHLYAGGKMISSYFRYQVGKLTGSNKRPG"
     gene            340822..342267
                     /locus_tag="HPDFL43_19622"
     CDS             340822..342267
                     /locus_tag="HPDFL43_19622"
                     /note="COG1012 NAD-dependent aldehyde dehydrogenases"
                     /codon_start=1
                     /transl_table=11
                     /product="Aldehyde dehydrogenase"
                     /protein_id="ZP_02164742.1"
                     /db_xref="GI:163757653"
                     /translation="MIEKREFYINGEWVGPRAGRDCEVIDPSTEEACAVISLGGTEDT
                     NAAVAAAKAAFDEWSQTDPETRLGYVKKIREIYLERAEDMSKAISLEMGAPIEMSRAS
                     QTTSGTWHIDNFITAFKDFKFLRPLGPHAPNDRIAMEPIGVAGLITPWNWPMNQVALK
                     VIPALLTGCTMVLKPSEVAPLSSIVFAEIVHAAGVPAGVFNMVNGDGMGVGTDLSTHP
                     DVDMISFTGSARAGAAISKAAADTFKRVCLELGGKGANLVFADADEKAVTRGVRHCFN
                     NTGQSCNAPTRMLVERPVYEQAIETAIKIAESTKVASAHQDGNHIGPVVSAAQYEKIQ
                     GYIQKGIDEGARLVAGGVGRPEGLNRGYFVRPTVFADVSNDMTIAREEIFGPVLSIMP
                     FDTEEEAVAIANDTIYGLTNYVQSQDGAKRNRLARRLRSGMVEMNGQSRGAGSPFGGT
                     KTSGRAREGGVWGLDEFLEVKAISGWDPAAE"
     gene            complement(342341..343339)
                     /locus_tag="HPDFL43_19627"
     CDS             complement(342341..343339)
                     /locus_tag="HPDFL43_19627"
                     /note="COG0604 NADPH:quinone reductase and related
                     Zn-dependent oxidoreductases"
                     /codon_start=1
                     /transl_table=11
                     /product="Alcohol dehydrogenase, zinc-binding protein"
                     /protein_id="ZP_02164743.1"
                     /db_xref="GI:163757654"
                     /translation="MKAMFCVARGAAGETLELHDVDTPAPGPGEVRVRMHTSGVNPSD
                     VKLRSGVQGPMVADRVVIHNDGAGVIDAVGEGVEPSRVGERVWLYNVNRSADGLGQGV
                     SGTAAELTCVPAALAAPLPDVASFEAGACLGVPAMTAHRAVTWAGPISGKTVLVTGGA
                     GAVGHSAIQIAKAMGARVIATISSQAKDAIARDAGADVVINYRSEDLEARITQEAGRN
                     GVEHVVEVDLAAHVTLYPKILAFDATVGAYASSSDMTPKLPFYPLAFRNICLQPVFVY
                     SMSDKAKGLAIADINALLTSGALTPRIDARFELADAVSAHQAVEGGQLTGNAILTI"
     gene            343563..343889
                     /locus_tag="HPDFL43_19632"
     CDS             343563..343889
                     /locus_tag="HPDFL43_19632"
                     /note="COG2076 Membrane transporters of cations and
                     cationic drugs"
                     /codon_start=1
                     /transl_table=11
                     /product="Small multidrug resistance protein"
                     /protein_id="ZP_02164744.1"
                     /db_xref="GI:163757655"
                     /translation="MVWFYLLIAIAGEVVGTTALKASNGFTHWGYAGFSFASYAFAFY
                     FLAIVLKTMPVGVAYAIWSGTGVAMVTMIGVFVFGQKLDLYAYLGIALIVAGVLVLNI
                     LSDTTA"
     gene            complement(343940..345493)
                     /locus_tag="HPDFL43_19637"
     CDS             complement(343940..345493)
                     /locus_tag="HPDFL43_19637"
                     /note="COG4262 Predicted spermidine synthase with an
                     N-terminal membrane domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164745.1"
                     /db_xref="GI:163757656"
                     /translation="MARPDCGDLPMTLSQARAPLALLVAIQAVVSGSSLVVEIVAGRM
                     LAPYVGMSLYTWTSIIAVVLAGFSVGHWWGGHVAERTARQALVYTGWVLLAAAFATGC
                     ALVLLRFTGGPVLESVGHPVVSIVILTICVFFLPSVFAGVPAPVLTQIAVTTRADKSG
                     RALGAMFAAGAVGAIAGTVLAGFLFIPWLGTAITLSIVTLVYLASAGLLFFMARPVQR
                     PGLPVLVAGLAIAMSAVTLTRLSYCSLESRYFCIKVLDVSADPASPVRRLVLDHLSHG
                     TSSREQPRLMFSEFTAMIDEIGRGRMGSEAFSTFFIGGGTYSVPRAWADRNTGPVTVA
                     EIDPDVTAIAVRDFWVAASQFEILHEDARRALLTRSERRYDVIVGDAFGDIAVPSHLV
                     THEFFTLVRDRLSDDGVFLMNVVDFPERLEALGAITATLQSVFPSVEVWTAQQPPVAG
                     EQRVFVLAAGSQPTPFSTIVTGASDPTRFAALADSFVQRLTERGGSIVLSDDYAPIDR
                     LLAGSLWGG"
     gene            complement(345752..346525)
                     /locus_tag="HPDFL43_19642"
     CDS             complement(345752..346525)
                     /locus_tag="HPDFL43_19642"
                     /note="COG0410 ABC-type branched-chain amino acid
                     transport systems, ATPase component"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter related protein"
                     /protein_id="ZP_02164746.1"
                     /db_xref="GI:163757657"
                     /translation="MNAVVAETGTTDFSKHRNHAATAPAFLSVHDIHAYYGESYIVQG
                     ISFNVHEGEILALLGRNGAGKTSTLRTLARLSNPTLTHGEIWLDHKPLHTMPSHEAAR
                     GGLILVPEDRRIIPGLTVEENLQLAQIVEPIGWSIERLYELFPRLGERRQQEGVTLSG
                     GEQQMLSIARALARDIKVLLLDEPYEGLAPVIVDEIEKTLAIIKAQGITTILVEQNAV
                     RALNLADRAVILDTGTVVFDGTAKEVLDNKELREEYLAI"
     gene            complement(346522..347277)
                     /locus_tag="HPDFL43_19647"
     CDS             complement(346522..347277)
                     /locus_tag="HPDFL43_19647"
                     /note="COG0411 ABC-type branched-chain amino acid
                     transport systems, ATPase component"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter,
                     ATP-binding protein"
                     /protein_id="ZP_02164747.1"
                     /db_xref="GI:163757658"
                     /translation="MGILEVKNVNKRFGGLQALGDVNLSVAENSVHAIIGPNGAGKST
                     LLNVLVGKLVPDTGTVTFDGNSVLGRTPFQINQMGISRVFQTPEIFGDLTVMENMLIP
                     CFAKRDGSFRMHAIESIASEHAIIERAEEMLTEVNMIDKREMHGASLSRGDKRRLEMA
                     MCLVQEPRLLLLDEPTAGMSRADTNNTIELLKEIHTKRNITMAIIEHDMHVVFSLAQR
                     ITVLAQGTPLVEDIPENIKGHPKVKEAYLGEAA"
     gene            complement(347295..348509)
                     /locus_tag="HPDFL43_19652"
     CDS             complement(347295..348509)
                     /locus_tag="HPDFL43_19652"
                     /note="COG4177 ABC-type branched-chain amino acid
                     transport system, permease component"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter,
                     permease protein, putative"
                     /protein_id="ZP_02164748.1"
                     /db_xref="GI:163757659"
                     /translation="MLGLQKKDFALLMFVAALTAFAPFLLNPFPVDSALAQFNAGYPD
                     LMQRFVIFGIFAVGFNILFGLTGYLSFGHAAFLGVGSYAAIWSMKLMTMNVIPAIILA
                     VIVAGLFSLFVGWISLRRSGIYFSILTLAFAQMSFALAYSVLTPITGGETGLQPKVAD
                     PRIFDAALGDGELPAANLFGLTMKSSYELNIGGWLFTFNAGYYVAAIVMLLAFYMAIR
                     IFRSPFGMMLRAIKTNQTRMNYTGLNPKPYTLAAFVISGMYAGLAGGLMVAMDTQVGP
                     ERMFWTASGEVVLMTILGGAGTLIGPVLGAGMIKYMENIISKINEGVLYEWFAFLPES
                     LQDLLVTIIYPFIGKGWHLTLGIVFMLVVIFLPGGLLEGGERIRNMLSRKKKADPGKD
                     PEHHPKPSPHVA"
     gene            complement(348514..349551)
                     /locus_tag="HPDFL43_19657"
     CDS             complement(348514..349551)
                     /locus_tag="HPDFL43_19657"
                     /note="COG0559 Branched-chain amino acid ABC-type
                     transport system, permease components"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="ZP_02164749.1"
                     /db_xref="GI:163757660"
                     /translation="MAMEAILLQILNGLDKGSAYALIALGLTLIFGTLGVVNFAHGAL
                     FMIGAFCAVIFSRILSLSTVTEDPTRKDFLGNPLKIETPYVESWFGPELGSVLINWSV
                     PLSIILAIPVMILVGLAMERGLIKYFYKRPHADQILVTFGLAIVLQEIIKYFFGANPI
                     PTPAPDVFAGSFDFGALIGLEAGQIIYPYWRLVYFAFAAAIIAAVFSFLQFTTFGMVV
                     RAGMADRETVGLLGINIDKRFTIMFAIAAVVAGLAGVMYTPINSPNYHMGMDFLVLSF
                     VVVVVGGMGSLPGAVLAGFLLGILESFASMAQVLSVVPGINQIIIYLVAIVILLTRPR
                     GLMGRKGVMEE"
     gene            complement(349674..351035)
                     /locus_tag="HPDFL43_19662"
     CDS             complement(349674..351035)
                     /locus_tag="HPDFL43_19662"
                     /note="COG0683 ABC-type branched-chain amino acid
                     transport systems, periplasmic component"
                     /codon_start=1
                     /transl_table=11
                     /product="Twin-arginine translocation pathway signal"
                     /protein_id="ZP_02164750.1"
                     /db_xref="GI:163757661"
                     /translation="MSKFSISRRGLIKTGAYVGAGLAMPTIFTSSANAFTNEPTGSTV
                     TLGFNVPQSGPYADEGADELRAFQLAVEHLNGGGDGGMLNTFSSKALQGSGIMGKKVE
                     FVSGDTQTKSDAARASARSMIEKDGAVMISGGSSSGVAVAVQALCQEAGVIFMAGLTH
                     ANDTTGKDRKANGFRHFFNSYMSGAALAPVLKNAYGADRKAYYLTADYNWGYTTEQAV
                     RESTEAVGWETVNNVLTPLTQTDFSSYIAPVLQSDADVLVLVHYGGNMVNSLTNAVQF
                     GLRDRMVNGKQFEIVVPLYSELMARGAGENVKGIFGSQNWDWKLENQLGSRYIGTNAF
                     VRSFGEKYGFPPSQAAHTCYVQTLLYADAVERAGSFNPCAVVEALEGFEFDGLGNGPT
                     LYRADDHQCFKDVVVVKGKENPESEFDLVEIVEVTPAEQVTYAPDHPQFAGGDLGTCN
                     PGA"
     gene            complement(351292..351540)
                     /locus_tag="HPDFL43_19667"
     CDS             complement(351292..351540)
                     /locus_tag="HPDFL43_19667"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164751.1"
                     /db_xref="GI:163757662"
                     /translation="MTVDAYILKSPEKSGSPATLLRAEFPLQENSEPDLATLVLKTPA
                     RRLKHIQHMLIYIFDLPKSIFVDFAQHGQIRGKIDRIL"
     gene            complement(351717..352142)
                     /locus_tag="HPDFL43_19672"
     CDS             complement(351717..352142)
                     /locus_tag="HPDFL43_19672"
                     /note="COG2010 Cytochrome c, mono- and diheme variants"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c family protein"
                     /protein_id="ZP_02164752.1"
                     /db_xref="GI:163757663"
                     /translation="MKKQSLLIGAALLIGAFFIYRGFGGPDHSPSAAQPGAAMANVLV
                     PELSAATRDGEALFVRSCADCHGTNAAGRDGIAPPLVHKIYEPNHHGDASFYLAARNG
                     VRAHHWRFGDMPPVEGLADTDIAKIVFYVRELQRANGIH"
     gene            352257..352355
                     /locus_tag="HPDFL43_19677"
     CDS             352257..352355
                     /locus_tag="HPDFL43_19677"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164753.1"
                     /db_xref="GI:163757664"
                     /translation="MVARFKLLNLTQATSALPEDLCAQITASLHKA"
     gene            complement(352360..354228)
                     /locus_tag="HPDFL43_19682"
     CDS             complement(352360..354228)
                     /locus_tag="HPDFL43_19682"
                     /note="COG2217 Cation transport ATPase"
                     /codon_start=1
                     /transl_table=11
                     /product="Heavy metal translocating P-type ATPase"
                     /protein_id="ZP_02164754.1"
                     /db_xref="GI:163757665"
                     /translation="MYQMSVLFHDRLNLALLGLSLFGLIGGLFLLLTGQPDFAKIVWT
                     TGVLPVLAALCLEIVRSLIKGEVGLDVVAALSMSAALLFGETLAAAVVALMYSGGTFL
                     ESFAQGRARREMSDLLARVPRTATRHCNGALDEVPLDDIVAGDLLLIRQGDVAPVDGT
                     VDSPSALLDQSALTGESMPVRLAKGQDVMSGSTNAGEAFDLRATRRAADSTYAGIVRL
                     VEAAQESKAPMARLADRYSLVFLIVTVVLATAAWWLTGDPIRAVAVLVVATPCPLILA
                     VPVALVAGLSRAAHYGVLIKGAKPLEALARINTLILDKTGTLTDGRPQIVSIDTRGGM
                     SEDEVLYFAAALDQASKHPIAQAIIAAAHARGSTLPVPQNLVETPGEGVTGTVDGLKV
                     VVGGTGFVGAQTGVAEAQSSIVEAGSVVVAVAVDGQLVGHLVMADALRRGTAGLLAGL
                     RRLRVRRILLATGDRRAVAEAVTKGLDLDAVRSELTPDQKVLLVLTERKNGPVMMVGD
                     GVNDAPALAAADIGVAMGARGAAASAEAADVVLLVDHLNRLLPGIEIAQRSRRIAIES
                     VVAGIGLSIVGMFAAAFGYLTPVQGALLQEVIDVAVILNALRALRIVPGQLDGQEE"
     gene            354292..354588
                     /locus_tag="HPDFL43_19687"
     CDS             354292..354588
                     /locus_tag="HPDFL43_19687"
                     /note="COG0129 Dihydroxyacid dehydratase/phosphogluconate
                     dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164755.1"
                     /db_xref="GI:163757666"
                     /translation="MADGRPVVIEGCQSSKDDTMNGNVPRLAGLQTSPSERCLGIGSA
                     LACSNPSAGSYAIWFCESFYGKNDVSALPVRIANDIKRRTAFQPGGPAQSRPDI"
     gene            354590..355132
                     /locus_tag="HPDFL43_19692"
     CDS             354590..355132
                     /locus_tag="HPDFL43_19692"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164756.1"
                     /db_xref="GI:163757667"
                     /translation="MLLDILPETGTVLEIASGSGEHIIHFASLFPALDWQPSDPSPEA
                     RASILAWSKAEQPVNVLPPLDIDAAGDQWPVQRADAMIAINMVHISPWPATQGLLKAA
                     GRLLPAGGVLFLYGPYRRDGHPLVQSNVDFDADLRARNPAWGIRRLEDLEETGGQSGL
                     SIASVAEMPANNLGVTFRRS"
     gene            complement(355162..355764)
                     /locus_tag="HPDFL43_19697"
     CDS             complement(355162..355764)
                     /locus_tag="HPDFL43_19697"
                     /note="COG0607 Rhodanese-related sulfurtransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Rhodanese-like protein"
                     /protein_id="ZP_02164757.1"
                     /db_xref="GI:163757668"
                     /translation="MIRYLNAVAIALMVLAGTAAADDLKVGITPQMQAVTVETPEGPM
                     EIRRIQDQNHEITGEFAKTSRACPPFCIQPVSPAQGVTTIGEVELIEMLKNPEAVVVD
                     SRTVDWFRGGSIPGAINLPYSEMGDRLNRLGCEPDFDGWDCANARPVALFCNGLWCGQ
                     SPTAIRAMIAAGYPAERIFYYRGGMQSWRVLGLSVTGDGK"
     gene            complement(355965..356051)
                     /locus_tag="HPDFL43_t21177"
     tRNA            complement(355965..356051)
                     /locus_tag="HPDFL43_t21177"
                     /product="tRNA-Ser"
     gene            356089..356277
                     /locus_tag="HPDFL43_19702"
     CDS             356089..356277
                     /locus_tag="HPDFL43_19702"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164758.1"
                     /db_xref="GI:163757669"
                     /translation="MAIFGPRPIPLTRSQSSCISPVRIGRHYSQDAPLGNRYLAALAH
                     NVLARAEQALGEAIAGTF"
     gene            356372..356668
                     /locus_tag="HPDFL43_19707"
     CDS             356372..356668
                     /locus_tag="HPDFL43_19707"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane protein"
                     /protein_id="ZP_02164759.1"
                     /db_xref="GI:163757670"
                     /translation="MSLIFLVVAVIAGLVDAIQSVAAHKPIFTPLIQSWNEASPATLE
                     LVADLFAGHLPLWVWDPAAIWVMAQPSFAVFLGLSLLFYLIGYRRKKPAGRFAA"
     gene            356764..357489
                     /locus_tag="HPDFL43_19712"
     CDS             356764..357489
                     /locus_tag="HPDFL43_19712"
                     /EC_number="1.8.4.11"
                     /note="COG0225 Peptide methionine sulfoxide reductase"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine sulfoxide reductase A"
                     /protein_id="ZP_02164760.1"
                     /db_xref="GI:163757671"
                     /translation="MGAPDPDKAKPDQAKPGKEGVALFLIDMFNRKTTMPTPAEILPG
                     RAEAMDVAQPHAVSGMALTPPYPDGFETACFAMGKFWGAEKRFWSLEGVYVTAVGYSG
                     GTTPNPTYQEVVTGLTGHAQSVMVVFDPARLAYADLLAMFFENHDPTQGMRQGSDIGT
                     FFRSVIFARDDVQVSAAEAAVVTYQQALAAAGLTAKLTTQIVPVGEFFFAEAHHQQYL
                     ARNPGGQSGLKPSGVLFPRGASS"
     gene            357691..358683
                     /locus_tag="HPDFL43_19717"
     CDS             357691..358683
                     /locus_tag="HPDFL43_19717"
                     /note="COG1744 Uncharacterized ABC-type transport system,
                     periplasmic component/surface lipoprotein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein precursor"
                     /protein_id="ZP_02164761.1"
                     /db_xref="GI:163757672"
                     /translation="MKRTLLSIVALAAMSASALAADIKPAIIYDLGGKFDKSFNEAAY
                     TGAEKFKTETGIEYREFEISNDAQREQALRRFARDGNNPIVMAGFSWGSALEKVAGEY
                     PDIDFAIIDMVVDKPNVRSVVYKEQEGSFLVGVMAAKASESGTVSFVGGMDIPLIRKF
                     ACGYKGGVMATNPDATVLEAMTGTTPEAWNDPVKGGEITKSQIDQGSDVVYAAAGGTG
                     IGVLQAAADAGKLAIGVDSNQNGLQPGKVLTSMLKRVDVAVYNAFSDAKNDSFSYGFS
                     VLGLAEGGVDYAMDENNAPLVTDDMKAAVEAAKADIIAGTITVHDYMSDNNCPY"
     gene            358823..359446
                     /locus_tag="HPDFL43_19722"
     CDS             358823..359446
                     /locus_tag="HPDFL43_19722"
                     /note="COG0349 Ribonuclease D"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ribonuclease"
                     /protein_id="ZP_02164762.1"
                     /db_xref="GI:163757673"
                     /translation="MADIRAHKGDISDQAMARYTGDIAVDTETLGLVPRRDRLCVVQL
                     SPGDGSADVIQIAKGQKRAPNLVALLTDRKRRKLFHYGRFDIAVLYNAFGVTTEPVFC
                     TKIASRLTRTYTDRHGLKDVTRELLEVDLSKQQQSSDWAAETLTPAQLEYAASDVLHL
                     HALTAKLTERLQRDDREAHAKACFEFLPTRAKLDLMGWEETDIFAHS"
     gene            complement(360184..360432)
                     /locus_tag="HPDFL43_19727"
     CDS             complement(360184..360432)
                     /locus_tag="HPDFL43_19727"
                     /note="COG3093 Plasmid maintenance system antidote
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164763.1"
                     /db_xref="GI:163757674"
                     /translation="MLLEEFMKPYGLSARKVAAMIGVPANRISEIVAGNRSVTADTAH
                     RLDRLFGMGVETWLSLQAHYDAALALQQHDYSEIRLYA"
     gene            complement(360487..360768)
                     /locus_tag="HPDFL43_19732"
     CDS             complement(360487..360768)
                     /locus_tag="HPDFL43_19732"
                     /note="COG3549 Plasmid maintenance system killer protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164764.1"
                     /db_xref="GI:163757675"
                     /translation="MIVSFANAETEAVFNGDPVKGLQPGICKTARRKLDQINSVSSVE
                     QLRSPPGNKLHPLTKDRSGQWAIRINDQYRICFRFENGSASLVEIVDYH"
     gene            complement(361061..362767)
                     /gene="rpsA"
                     /locus_tag="HPDFL43_19737"
     CDS             complement(361061..362767)
                     /gene="rpsA"
                     /locus_tag="HPDFL43_19737"
                     /note="COG0539 Ribosomal protein S1"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="ZP_02164765.1"
                     /db_xref="GI:163757676"
                     /translation="MSQTETMTEDFASLFAESLATQDLSEGYVAKGTVMAIEKDVAII
                     DVGLKVEGRVPLKEFGAKAKDGTLKVGDEVEVYVERIENALGEAMLSREKARREESWV
                     RLEEKFTAQERVEGVIFNQVKGGFTVDLDGAVAFLPRSQVDIRPIRDVSPLMHIPQPF
                     EILKMDKRRGNIVVSRRTVLEESRAEQRSEIVQNLEEGQTVEGMVKNITDYGAFVDLG
                     GIDGLLHVTDMAWRRVNHPSEILSIGQTVKVQIIRINQDTHRISLGMKQLESDPWDGI
                     GVKYPAGKRITGTVTNITDYGAFVELEPGIEGLIHVSEMSWTKKNVHPGKILSTSQEV
                     DVVVLEVDPNKRRISLGLKQTLENPWDVFAQSHPAGTEVEGEVKNKTEFGLFIGLEGD
                     VDGMVHLSDLDWNRPGEQVIEEYNKGDMVKAVVLDVDVDKERISLGIKQLGKDSIGEA
                     AASGELRKNAVVSAKVTGVTDGGLEVVLVDHEDLSSFIRRSDLSRDRDEQRPERFSVG
                     QTVDARVTSFSKKDRKVGLSIKALEIAEEKEAVAQFGSSDSGASLGDILGAALKKQNS
                     DD"
     gene            complement(362905..363546)
                     /locus_tag="HPDFL43_19742"
     CDS             complement(362905..363546)
                     /locus_tag="HPDFL43_19742"
                     /note="COG0283 Cytidylate kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase"
                     /protein_id="ZP_02164766.1"
                     /db_xref="GI:163757677"
                     /translation="MKDTHIIIAIDGPAAAGKGTLSRRLAARYGLHHLDTGLTYRATA
                     KALLDRGLPLDDEGLAADVARNLDLSSLDRSVLAVHEVGEAASKVAVMPKVRRALVEA
                     QRDFAATAPGTVLDGRDIGTVVCPDALIKFYVTASPEVRAQRRYEEIIGQGGSADLAG
                     ILADLKKRDARDSERTDSPLKPAPDAHLLDTSEMGIEAAFEAARVLVDAALQT"
     gene            complement(363571..364197)
                     /locus_tag="HPDFL43_19747"
     CDS             complement(363571..364197)
                     /locus_tag="HPDFL43_19747"
                     /note="COG2808 Transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="ZP_02164767.1"
                     /db_xref="GI:163757678"
                     /translation="MYLPPQFAETDEDVMRALIAAHPLGLLISASETGVQANPVPFLV
                     SSEDGATRLRAHLSRANPQWRHLQDGASVLVVFQGDDTYVTPSWYQSKAEHGKVVPTW
                     NYAMVQARGSASVEEGPDWLAQQVGALTDRHEAGRNAPWKVEDAPDKFVKAQLRGIVG
                     IEIAVRELTGKWKVSQNRQEADRQGVHAGLTKDGAVEMAELVRRYGGL"
     gene            complement(364233..364892)
                     /locus_tag="HPDFL43_19752"
     CDS             complement(364233..364892)
                     /locus_tag="HPDFL43_19752"
                     /note="COG3917 2-hydroxychromene-2-carboxylate isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="DSBA oxidoreductase"
                     /protein_id="ZP_02164768.1"
                     /db_xref="GI:163757679"
                     /translation="MSGRTIDFCYDLISPFAHVALKRLDELPADVTVRPVPVLLGAIL
                     THWGQRGPAEISAKRLHTYRLSVFLGQQHGLEIRFPPRHPFNPLKALRLLAGREADLT
                     KVQAAFDFVFEQGRAPDTEEELAALAAAIGVPVSLAEDDAAKSALRANTDQAIARGVF
                     GVPSFVVPAVSGHPTSSGQEVFWGVDAFDMLLAWLDDPGLFEQHRYSHLDDVSIGIAR
                     K"
     gene            complement(364889..366151)
                     /locus_tag="HPDFL43_19757"
     CDS             complement(364889..366151)
                     /locus_tag="HPDFL43_19757"
                     /note="COG0128 5-enolpyruvylshikimate-3-phosphate
                     synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="ZP_02164769.1"
                     /db_xref="GI:163757680"
                     /translation="MFGGLANGETRITGLLEGEDVINTGKAMQAMGASIRKEGDAWVI
                     NGVGNGCLLAPEKPLDFGNAGTGCRLTMGLVGPYDFDTTFVGDASLSRRPMGRVLDPL
                     RLMGVQVRSEDGDRLPVTLHGPLAPAPISYRVPMASAQVKSAVLLAGLNVPGVTTVIE
                     PVMTRDHTEKMLAGFGAQLEVETGADGVRTIRLEGRGTLTAQIIDVPGDPSSTAFPLV
                     AALLVPDSDVTIRNVLMNETRTGLILTLQEMGANIEIIDPRQAGGEDVADLRVRSSEL
                     TGVNVPADRAPSMIDEYPVLAVAASFAEGETVMTGLDELRVKESDRLSAVARGLEING
                     VDCTEGDDWLSVRGRPDGKGLGARSEKAVVKTWLDHRIAMSFLVMGLASEHPVHVDDS
                     AIIATSFPEFMDMMTGLGARIDIGSARG"
     gene            366150..366320
                     /locus_tag="HPDFL43_19762"
     CDS             366150..366320
                     /locus_tag="HPDFL43_19762"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164770.1"
                     /db_xref="GI:163757681"
                     /translation="MKDLWEIDLSPGIRISPLSDRLFDALAGRRGISAWPIVDFQAVE
                     VGSAAKLTVALG"
     gene            366483..366896
                     /locus_tag="HPDFL43_19767"
     CDS             366483..366896
                     /locus_tag="HPDFL43_19767"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164771.1"
                     /db_xref="GI:163757682"
                     /translation="MAKPELGTKRVCPETGRKFYDLNKDPIVSPYTGTSYPLSFFEET
                     SKAVVLEKEQEKEEQEEVAELDDETADVEIVSLEEADEDTTKTGKSDDIPDIDDDADV
                     DLEDDEDDTFLADDDDDDDDDVSDIIGVNDDDDDH"
     gene            367067..367139
                     /locus_tag="HPDFL43_t21171"
     tRNA            367067..367139
                     /locus_tag="HPDFL43_t21171"
                     /product="tRNA-Ala"
     gene            367438..368880
                     /locus_tag="HPDFL43_19772"
     CDS             367438..368880
                     /locus_tag="HPDFL43_19772"
                     /note="COG0382 4-hydroxybenzoate polyprenyltransferase and
                     related prenyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164772.1"
                     /db_xref="GI:163757683"
                     /translation="MDALSDNRHVPLCIDLDGTLIATDSLWEGLVSVLIRRPWLFFAA
                     IFWALSGKAVLKREIAARLAHKGADWPYRDEVIARIKQAREAGQPVWLVTGAAESTAK
                     AVADHLGLFDRVLHSTDAENLTSSRKRERLVSICGDGGFDYAGNSRDDLAVFDAARRA
                     IIVAPDSAARKWGAKNRAEFLPLAQISPLAILKSIRVHQWLKNVLIAVPLVLNHEFAD
                     TNLVLAAIAAFFSFSFLASAVYIVNDISDLANDRQHPRKRLRPLASGAVSVPVISVAA
                     VALLAASVALASLLPPLFWAVLAMYATITTAYTFVLKRKLLVDVFTLAALYTLRIVAG
                     AAATGTDLSFWLLAFSIFFFLSLALVKRYVELDELANSDDAQLKGRGYAGSDKDMIGQ
                     AGVASAFSAAMVLALYVHSDEVTSMYAQPWLLWPLCPLILYMLLRIWILARRSQMHDD
                     PVVFIMRDWRSQVTTFVGAALVILATLNVW"
     gene            368874..370229
                     /locus_tag="HPDFL43_19777"
     CDS             368874..370229
                     /locus_tag="HPDFL43_19777"
                     /note="COG0277 FAD/FMN-containing dehydrogenases"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD linked oxidase, N-terminal"
                     /protein_id="ZP_02164773.1"
                     /db_xref="GI:163757684"
                     /translation="MVNMQSELNSWGRVVRCPRATTGLASLTGSAAGAMLPYGNGRSY
                     GDSCHNDSGRLVPMRPGSAIRAFDPDTGLLTADAGVLLSEILTLVMPHGYFLEVTPGT
                     AQVTLGGAIANDVHGKNHHRRGTFGRSVISFELFMSDDRRVTCSPDQNRQLFEATIGG
                     MGLTGVIEAATIRLMKVPSANVRQTAFRFGSIDDYFDAIDAIDAKHEYSVAWIDQLAR
                     GANLGRGVLMAGDHAEDGGPAKPPAPPRLAIPFSPPVNLLNRLTLKAFNALYFGRAPK
                     SAATAIVPWGSYFHPLDAIRDWNRLYGPGGLFQHQSVYPAETARETTIRLIECAQSRG
                     AASFLTVLKRFGDVPSPGLLSFPRPGFTLTLDFANSGPATLKMLDALDEIVLSAGGAL
                     NPYKDQRMSAEMFETSFPNWRELEAIRDPALMSDFWRRTAMQLKPVEDAEAQAQAAKS
                     A"
     gene            370340..371317
                     /locus_tag="HPDFL43_19782"
     CDS             370340..371317
                     /locus_tag="HPDFL43_19782"
                     /note="COG0240 Glycerol-3-phosphate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Adrenodoxin reductase:NAD-dependent
                     glycerol-3-phosphate dehydrogenase"
                     /protein_id="ZP_02164774.1"
                     /db_xref="GI:163757685"
                     /translation="MSRISILGAGAWGTALAAAFTLQGHTVRLWGRSSEICDEINRHH
                     TNRAYLDTASLPEGLSASTDMSAVLSDAETVLFVSPAQTTAEIAARAVQSLPPGATVV
                     ACAKGIDNQTGRMQSELIADHLPGHPIGVLSGPSFAADVVRGLPTAVTLAMADLDLAQ
                     ALAQSLSGGAVRIYASDDVIGVQIGGSLKNVMAIAVGICRGGRMGASAEAALVTRGYA
                     ELVRLGVAMGARPETLMGLSGLGDLVLTCSSELSRNFAYGVAVGSGRDVTGLKLAEGV
                     HTVAIANTLAAQHQIVCPVMQTAGEVLAGRMSADEARIALMSRPLRVED"
     gene            371432..373741
                     /locus_tag="HPDFL43_19787"
     CDS             371432..373741
                     /locus_tag="HPDFL43_19787"
                     /note="COG0836 Mannose-1-phosphate guanylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannose isomerase"
                     /protein_id="ZP_02164775.1"
                     /db_xref="GI:163757686"
                     /translation="MPIECGQSQGRSSGEAFPEHFMGSRHTITPVVLCGGAGSRLWPM
                     SRDSKPKQFHKLVNDKTLLTNTLERVDHKGEGLRYLPTRIVGGVAFESLLVEQGETGS
                     VEVERYILEPLIRDTAAAIAAAIADLAESDPQRMVLVLPSDHQISGTSAFFEVIRTGA
                     DALAERGGIMTIGITPTRPETQYGYIERGEGNGPVYDVTRFREKPDLETAETFLRSGR
                     FFWNGGIFMFRAGEMAAELARQQPEVWAQAKRAVENAVIDGKCCRLDAEAFAASPKIS
                     IDYAVMENAPVIGVVAASFDWNDLGSWNQLHDGSPLDEAGNARFGDVLTIDVRNSYLR
                     SEDRLLTVAGLENIIVVSQPDALLIVHRDKSHLVKDIANEVKQSGEWPPLAVAHSGRP
                     VPSPRVIRKWLFDTALPLWAGAGIDRQYGGVHEALNHDGTPADHGYKRLRVLARQIYC
                     FAYARLLGWEGGPPDLLEHCFKTLVETGWHESGGWIHLWNPDGTVKDAQRDTYDQCFV
                     LLALAWLWRATKWPEARVWAERTIAYMDENLVDRANGGFYESSLRLDYRRANPHMHYL
                     EAMQAWYEVTGERAFLDRAQTSVDLFTNVFFDPESWSVTEHFNRDWSVRADKPTRIEP
                     GHHYEWVWLLLRQARFTDHPQLKEYCRKLYATSHAFGHARGTDAVCDSMAPDGSDMIG
                     TARLWCQTEALKAGLLARADGLPGDETLFIRMLDVIFNRYLTAPTPGGWYDQIDPNGR
                     VISKDMPTSSFYHVFCALVEYLRHEELLP"
     gene            373773..375203
                     /locus_tag="HPDFL43_19792"
     CDS             373773..375203
                     /locus_tag="HPDFL43_19792"
                     /note="COG1109 Phosphomannomutase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="ZP_02164776.1"
                     /db_xref="GI:163757687"
                     /translation="MMAAKFGTSGLRGLVGDLTDGTASAHARAFARHLGSHAMAQPGS
                     PIFIGRDMRASSPEIARQCAAAVRAEGYVPVDCGVVPTPALALHAMGRGAAALMITGS
                     HIPDDRNGVKFYRPDGEIDKTDETAISALAPEFLGQTLPDAAPMQSEHDKVLDAFVAR
                     YRGFVAGEGLHGLRIGLYEHSSAASEALARILTEAGAAVIRLGHSHRFIPVDTEAVSD
                     ETRRLTAGWVQSESLDGLVSADGDGDRPLVVDETGSVLRGDALGLIVARHLGADAVVT
                     PVTSNSGIEDHCDARVWRTRVGSPFVIAGMNAALEEDMRRVIGFEANGGVLTGNVIES
                     SQARLAPLPTRDSVLPILCAFAAARQAGQSLSAHVASLALPVAASDRIENFPTAQSQQ
                     LVVRLSGDAAVCAGFFATLGTVGHIDRTDGLRVTLEDGRIVHLRPSGNAPEMRVYSEA
                     GSLADAQAVIAATMALVKQSAGDQIR"
     gene            375292..376230
                     /locus_tag="HPDFL43_19797"
     CDS             375292..376230
                     /locus_tag="HPDFL43_19797"
                     /note="COG0329 Dihydrodipicolinate
                     synthase/N-acetylneuraminate lyase"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthetase"
                     /protein_id="ZP_02164777.1"
                     /db_xref="GI:163757688"
                     /translation="MDNSIFTGCMPALMTPCKADRTPDFDALVRKGQELIAAGMSAVV
                     YCGSMGDWPLLTDAQRMAGVERLVAAGIPTVVGTGAINSAAAVAHAAHAAKIGAQGLM
                     VIPRVLSRGASAAAQAAHFKAILSAAPDLPAVIYNSPYYGFATRADLFFALRKDHPNL
                     IGFKEFGGAEDLRYAAENITSADDSVTLMVGVDTNVYHGFVNCGATGAITGIGNALPR
                     EVLHLVALCQKAAGGDAEARVQAKELEEALGVLSSFDEGADLVLYYKHLMVLNGDEEY
                     TLHFNETDALTDSQRNYAESQYHLFKSWYADWKAKT"
     gene            376482..377093
                     /locus_tag="HPDFL43_19802"
     CDS             376482..377093
                     /locus_tag="HPDFL43_19802"
                     /note="COG1198 Primosomal protein N' (replication factor
                     Y) - superfamily II helicase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164778.1"
                     /db_xref="GI:163757689"
                     /translation="MSKFRYYTAKSPKKGLDLKKAVHTNFLRTGRIARDAEDWLEEER
                     RFLTYQEVAERTGVRLENAGKKTHQRLNTFHYDIQFPKIIFHKTLATAPHLGYVHVTA
                     SKTDFAEYKGVTWGFYIANFTAEITADEQFFNRINPNYSRMYFAVAMKTEENAAQRRQ
                     IINRDFRENGVLFRTTDPKTALKNVLLLGAKSAELRKIVEAIG"
     gene            complement(377360..377443)
                     /locus_tag="HPDFL43_t21175"
     tRNA            complement(377360..377443)
                     /locus_tag="HPDFL43_t21175"
                     /product="tRNA-Leu"
     gene            377721..378659
                     /locus_tag="HPDFL43_19807"
     CDS             377721..378659
                     /locus_tag="HPDFL43_19807"
                     /note="COG0697 Permeases of the drug/metabolite
                     transporter (DMT) superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164779.1"
                     /db_xref="GI:163757690"
                     /translation="MAQDLAPPPSIKTPAPDPVENRRGVLLVLGAAIIWSFGGAIARG
                     LETGDPWAIVAWRSIFAALFLLAFMLWRDGPTGTIRLFRTMGLPGVGVGLCFATASMS
                     FVVALGYTSVANILLMQAGAPLIAALLGVIFLREAVDRVTWAAILAVIAGVGVMVSDS
                     FAANVSFIGDGLALLIAVVFAAATVITRRYSDVRMTPAVCLGVIIGAAFGISLAQTLV
                     VSIRDLGLLVLFGAFNLGLGLAMFVTGARLIPSALAALISTMEPVFGPIWVWILHSEV
                     PASRTLVGGVMVFLALIGHILWQWHKSRRTALPLPN"
     gene            complement(378727..380535)
                     /locus_tag="HPDFL43_19812"
     CDS             complement(378727..380535)
                     /locus_tag="HPDFL43_19812"
                     /note="COG0481 Membrane GTPase LepA"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding elongation factor protein"
                     /protein_id="ZP_02164780.1"
                     /db_xref="GI:163757691"
                     /translation="MTNTPLSHIRNFSIVAHIDHGKSTLADRLIQTCGGLAEREMSQQ
                     VLDSMDIEKERGITIKAQTVRLHYKAKDGEMYVLNLIDTPGHVDFAYEVSRSLRACEG
                     SLLVVDASQGVEAQTLANVYAALDADHEIVPVLNKIDLPAAEPDRIKEQIEEVIGLDA
                     SDAVMISAKTGIGIPEVLEAIVTRLPAPKGGTTKDALKAMLVDSWYDTYLGVIVLVRV
                     IDGEMKKGQQIRLMGTGARYTVERIGIITPKLVATDTLGPGEIGFITASIKEVADTRV
                     GDTITEEKHPTAEALPGFKPAQPVVFCGLFPVDAADFEDLRAAMGKLRLNDASFSFEM
                     ETSAALGFGFRCGFLGLLHLEIIQERLEREFNLDLIATAPSVVYRMNMTNGDVIELHN
                     PADMPDVVKIASIEEPWIKATILTPDDYLGPILKLCQERRGIQTDLSYVGKRAMVTYQ
                     LPLNEVVFDFYDRLKSITKGYASFDYQITGHEAGDLVRMSILVNEEPVDALSMLVHRS
                     AAEKRGRVMCEKLKDLIPRHMFKIPIQAAIGGRVVARETISAMRKDVTAKCYGGDATR
                     KRKLLDKQKAGKKRMRQFGKVEIPQEAFIEALKIGD"
     gene            complement(380733..381959)
                     /locus_tag="HPDFL43_19817"
     CDS             complement(380733..381959)
                     /locus_tag="HPDFL43_19817"
                     /note="COG0451 Nucleoside-diphosphate-sugar epimerases"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="ZP_02164781.1"
                     /db_xref="GI:163757692"
                     /translation="MGRTNTCCQEWGSMKIVVTGASGYVGRHLVPLLADRGADLLLAG
                     RDPDKLGEMFPGQAVCGYSELAEAAQGYTMLLHLAVLNTGSDASLEAFIKVNVEQMME
                     MAALAQSAGIETFVNASSIHALDPSNKAPYAISKKMAAKKLASFDGLNTVNLYLPYVY
                     DPDFKTRFRFAAKLPKPLGRLAFQAATCLKSSVNVSRIADFMISLSGQGPTDLPQPLI
                     LSEGQSGNPVFQITKRTIDLGFAICILVLLWWLLIAIFVLIRLDSKGPGLFLQERVGK
                     DGKVFSCYKFRTMKTGTAHVGTHEVSTSAITRQGQWLRKSKLDELPQIINIFRNEMSL
                     VGPRPCLPSQSELIAERDQRGVLAVKPGITGLAQVNGVDMRFPAKLAQWDARYLALQS
                     LLLDLRILLATAFRRG"
     gene            complement(382029..382127)
                     /locus_tag="HPDFL43_19822"
     CDS             complement(382029..382127)
                     /locus_tag="HPDFL43_19822"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164782.1"
                     /db_xref="GI:163757693"
                     /translation="MQPFAIGLMLRLHNRDAPESEWQAPDRSIGKT"
     gene            complement(382313..383275)
                     /locus_tag="HPDFL43_19827"
     CDS             complement(382313..383275)
                     /locus_tag="HPDFL43_19827"
                     /note="COG0464 ATPases of the AAA+ class"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164783.1"
                     /db_xref="GI:163757694"
                     /translation="MPLLFSSAANAKLKESGLILSDSTAKCSTMTEARETTETLLDRL
                     GRFLARRLNSPNTDYEPYTPSDPETLSRTLEPGDILLIEGNQKVSAAIKYLTQSTWSH
                     AALYVGDALQTDPAARAGENESADRLAAAAEKPQLVEVNLGEGCVAVPLSKYARFNTR
                     ICRPVGLTPEDRKAIVTYMVERLGVRYDMKNIFDLMRYFLPTPPVPVRWRRRMLAFGS
                     GDPTRAICSSMIAQAYQSVKYPILPETTRIPGRQCADSDYSRREILHIRHHSLFAPRD
                     FDLSPYFRVVKPTLEYGFDYKQLHWSKKTDASSDHSGHIPQSTN"
     gene            383312..384295
                     /locus_tag="HPDFL43_19832"
     CDS             383312..384295
                     /locus_tag="HPDFL43_19832"
                     /note="COG1633 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164784.1"
                     /db_xref="GI:163757695"
                     /translation="MLTRLIGFNRRPFSSLSEQEVLALAISSEEDDSRIYLAYADHLR
                     EDYPQSAKVFDEMAQEEGAHRARLIDRHKARFGDRIPLIRREHVRGFYERKPDWLIKS
                     QPLDKIRQTAEDMEAQAHNFYLAAAQRTGDADTRQLLGDLAIAEKGHGSLARRLGLEH
                     TPEDIKSEEDQTARRKFILTYVQPGLAGLMDGSVSTLAPIFATAFATGDTWTTFLVGL
                     SASVGAGISMGFTEAAHDDGVISGRGSPLKRGLASGIMTAVGGLGHALPYLIPDFTIA
                     TTVAVAIVFIELWAIAWIQNHWMETPWSRAIFQVVLGGALVFAAGILIGNA"
     gene            384395..386341
                     /locus_tag="HPDFL43_19837"
     CDS             384395..386341
                     /locus_tag="HPDFL43_19837"
                     /note="COG1086 Predicted nucleoside-diphosphate sugar
                     epimerases"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein CapD"
                     /protein_id="ZP_02164785.1"
                     /db_xref="GI:163757696"
                     /translation="MLQNFVVWLLARDRRVKQLVLVAADTFIVVFGAWLAYCIRLDAI
                     YVPNQSQLVMILSAPLIAIPIFFGFGMYRSLIRYVGQEAIWSAFKAVGLTALLWGLLA
                     FMTRAYGIQGVPRSVLVLTWLFVLVMVISLRFWARWFLVTQSSGSVPRRYFLIYGAGE
                     AARQIASTLQSQNPRLSVIHATDDPSLYGRLIGGNAVFPSKDVPDLVRRYEIKDAIIT
                     LRYTSNAKRMDVVESLRKQGVRVRILPPFADIVDGKHMVNMVREVEIGDLLGREMATP
                     DKKLMEINTSGKVVLITGAGGSIGSELCRQAISLRTSKLVLLENSEVALYQIMRELSQ
                     KGDLEIVPILGSVMDQPLVKRLFDEHGVNTVFHAAAYKHVPLVEDNPFQGVINNSLGT
                     LSVATAAFESNVEVMVLVSTDKAVWPSSVMGASKRIAELIIQDFAAKSKRDKLSKTFC
                     AVRFGNVIGSSGSVIPLFREQIRSGGPLTLTDTGATRYFMTVSEAAQLVIQAGSIARP
                     DSKQSESEGDIYLLDMGDPVLIRDLAVKMIQLSNLTVCDETNPQGDIAMQIIGLRPGE
                     KLHEVLRYSVKEPNPTAHPKISVASEPPAEALDFDQLYADLRQIAAAHDHDRLMELLS
                     RVTGLSRPEDGDESNPDSSCPRTV"
     gene            386573..387910
                     /locus_tag="HPDFL43_19842"
     CDS             386573..387910
                     /locus_tag="HPDFL43_19842"
                     /note="COG0477 Permeases of the major facilitator
                     superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164786.1"
                     /db_xref="GI:163757697"
                     /translation="MVLLTGADHQDDRADCEEQIPIVSAKPRRIEPLTLLIGVSMTIG
                     YGTLYYPFAILGPEIARAQGWSNSFVFGVFSVALLTSAATASVVGHAMDRFGARPVMV
                     VGSFFATCVLVNLSFVETMVGFAVAMLLIEFAARMVQYETGFAALTALHGRNARRPIA
                     HVTLVAGFASTVFWPLIHWLLGFMDWRGVFLVLAAINFLVALPIHMLVPNRPELRAAD
                     RNDEPEPQTASAAGLVAQPLRDPGLLQPGRRMPAFLLLSLAFAGGSFLMSAVHTSFFL
                     ILDQMGRAAALAALAGAVIGPMQVAARLIEMVTGERVASSMVGLISTGTLFLGIVILA
                     AGLWFDADLVIIAFAVSFGIGQGLNFIARAILPARLFGTDGYGAMTGKLATIRLFAMA
                     GAPFCTALALTHAGIGITFAMLIGIAAVSVAASWALWGIERRCGSAQALASAQ"
     gene            complement(387948..388526)
                     /locus_tag="HPDFL43_19847"
     CDS             complement(387948..388526)
                     /locus_tag="HPDFL43_19847"
                     /note="COG3672 Predicted periplasmic protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164787.1"
                     /db_xref="GI:163757698"
                     /translation="MMVASAAFFAFTGVSGSTGLSMQTGRITSQPIGHYEFCKQFSSE
                     CEPVKGSGAAPKVTDYGWEVIREINRAVNFSVMPKTDLELFGKEEVWAYPQIAGDCED
                     YVLLKRHMLMERGFSAADVLITVVRKPDGEGHAVLTLRTSEGDFVLDNLEDDVKLWRD
                     TPYSYLKRQASNNSGRWVTIENSTEVMVGALR"
     gene            complement(388738..389538)
                     /locus_tag="HPDFL43_19852"
     CDS             complement(388738..389538)
                     /locus_tag="HPDFL43_19852"
                     /note="COG0596 Predicted hydrolases or acyltransferases
                     (alpha/beta hydrolase superfamily)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164788.1"
                     /db_xref="GI:163757699"
                     /translation="MTMNPIAKELTVGDGNAARPIAALMRAATGIGRDLPGVVWLGGY
                     RSDMSGSKAVALCDKAGEEGRAALRFDYSGHGASGGEFREGTISRWLEESLAAFDTFT
                     SGPQILVGSSMGGWVALRMVQELRKRGEGERIAGLVLIAPAPDFTLELMEPELTEAQR
                     EALERDGYYEEPTPYGPDPNVFTRALFEDGRKNRVLEGLIETGAPVHIIQGMADPDVP
                     WQHALKLMEHLPSENVTLTLIRDGDHRLSRDEDIARILAAVESIPAGS"
     gene            complement(389620..389832)
                     /gene="infC"
                     /locus_tag="HPDFL43_19857"
     CDS             complement(389620..389832)
                     /gene="infC"
                     /locus_tag="HPDFL43_19857"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="ZP_02164789.1"
                     /db_xref="GI:163757700"
                     /translation="MVLAFSIDELDLCGPDVLVRAGAFIGGRRRSERSANGFGLLNNW
                     SGSADCEARAQMFSRNVLISGRLSIA"
     gene            389839..390261
                     /locus_tag="HPDFL43_19862"
     CDS             389839..390261
                     /locus_tag="HPDFL43_19862"
                     /note="COG0290 Translation initiation factor 3 (IF-3)"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3 protein"
                     /protein_id="ZP_02164790.1"
                     /db_xref="GI:163757701"
                     /translation="MATDQALAMAEEAGLDLVEINSNGDVPVCKIVDLGKLKYQSQKK
                     ASEARKKQKTVEVKEIKMRPNIDTHDYDVKMRAMNRFFDEGDKVKVTLRFRGREMAHM
                     ELGMKLLQKVKDDTVEIAKVEAEPKLEGRQMMMVLAPK"
     gene            390525..390725
                     /gene="rpmI"
                     /locus_tag="HPDFL43_19867"
     CDS             390525..390725
                     /gene="rpmI"
                     /locus_tag="HPDFL43_19867"
                     /note="COG0291 Ribosomal protein L35"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="ZP_02164791.1"
                     /db_xref="GI:163757702"
                     /translation="MPKMKTKSSAKKRFKITATGKVKSAAAGKRHGMIKRSNKFIRDA
                     RGTMVLSEPDAKIVKKFLPNGL"
     gene            390763..391164
                     /locus_tag="HPDFL43_19872"
     CDS             390763..391164
                     /locus_tag="HPDFL43_19872"
                     /note="COG0292 Ribosomal protein L20"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="ZP_02164792.1"
                     /db_xref="GI:163757703"
                     /translation="MARVKRGVTAHAKHKKVLKKAKGFYGRRKNTIRAAKAAVDKSMQ
                     YAYRDRKVRKRNFRALWIQRINAAVREHGLTYGRFIDGLTKAGIEVDRKVLSDMAIHD
                     AEAFGVLVAAAKKELEYLKDKTPNEFESAVA"
     gene            391256..392119
                     /locus_tag="HPDFL43_19877"
     CDS             391256..392119
                     /locus_tag="HPDFL43_19877"
                     /note="COG3642 Mn2+-dependent serine/threonine protein
                     kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="Mn2+-dependent serine/threonine protein kinase"
                     /protein_id="ZP_02164793.1"
                     /db_xref="GI:163757704"
                     /translation="MGDDTNKDEVLSADELSQVLHALAGSPDRRITPINISGRRVWIK
                     RYDIEPRALAKRLHWLISPILFPVFLRGSEPALGEAGVERECSKLAAFRAAGFQTPDV
                     VYRSGATLVLSDVSPILTEQLAGATELERRELLPILFAVLGRIHSMGLVHGRPHLRDM
                     SMRNGDICFFDFEEAPETTMPLADAQARDLWLMMLPVVAAESDTGQCRLLLQAWLNRA
                     PVASIAALLRFLKFCRPLLGLARLVPVSLQGSDLKRFLGTARFLVASISDMDSAIATN
                     GHRAGSQQVKS"
     gene            392116..393201
                     /locus_tag="HPDFL43_19882"
     CDS             392116..393201
                     /locus_tag="HPDFL43_19882"
                     /note="COG0016 Phenylalanyl-tRNA synthetase alpha subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase alpha subunit"
                     /protein_id="ZP_02164794.1"
                     /db_xref="GI:163757705"
                     /translation="MSQYQTLESSIMAEISGASDEAAIEAVRVAALGKKGSVSELLKG
                     LGKMSAEERQEAGPAINGLKTRVADAISARKTELRDAAITERLAHESVDISLPARTSP
                     VERGRIHPISQIVDEITAIFADMGFSIAEGPDIETDYYNFTALNFPDGHPAREMHDTF
                     FLEPDANGERKVLRTHTSPVQIRTMEAQTPPIRIVIPGKTYRQDSDATHSPMFHQVEG
                     LVIDKQANVGHLRWVLEEFCKAFFEVDNVTMRFRPSFFPFTEPSFEVDIQCDRTSGPI
                     VKFGEGSDWMEILGCGMVHPNVLRAGGLDPDEYQGFAWGMGLDRIAMLKYGMPDLRDF
                     FNADVRWTSHYGFRPLDVPTLFGGLSA"
     gene            393228..395639
                     /locus_tag="HPDFL43_19887"
     CDS             393228..395639
                     /locus_tag="HPDFL43_19887"
                     /note="COG0073 EMAP domain"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase beta subunit"
                     /protein_id="ZP_02164795.1"
                     /db_xref="GI:163757706"
                     /translation="MKFTLSWLKDHLETDATLDQICERLTAIGLEVEDVDDKKAYQPF
                     VIAKVLSAEKHPEADRLKVLSVDAGDGNPVQIVCGAPNARAGLVGALARPGTYVPGID
                     VTLSVGKIRGVESHGMMCSERELDMSDEHDGIIDLPDDAPVGTPFAAYAGLDDPVIEI
                     NLTPNRPDCTSIFGIARDLAASGLGTLKAPKAPEFAVEGETTQNVKLILDDESLCPGF
                     AWRLVRGVKNGPSPKWMQKRLLAIGLRPISALVDVTNYMTFDQGRPMHVFDADKVKGD
                     LVVRRAQEGEEILALDTRTYKLNPSNVVIADDNGPESIGGIMGGEHSGCDENTTNVLI
                     ESALWDPINIAKTGRSHSIITDARYRFERGVDPEYMVPGLERTTELVLEMCGGKAAAA
                     RVEGYKGHQKKIVDFPFSEVRRLTGLSVSNEEARAILNGLGFEVSGSGETVQVAVPSW
                     RPDVDGKADLVEEVMRVHGVDNIKPEPLPTMGAVNEKILTTLQIRTRLAKRALASRGM
                     LEAVTWSFISEEQAKLFGGGDRSLKLANPIAADMSDMRPSLLPGLISAAGRNGARGYG
                     DVALFEVSGTYENDTPKGQRRVAGGVRRGTAGLNGGGRHWDGAAKPVGVFDAKADAIA
                     VLEACGAPVDRLSFERGAADWYHPGRSGLIKLGPKTVLGHFGEFHPNTLDALDVSGPL
                     CGFEVFIDAIPEPKRKVTRTKPVLELSAFQAVRRDFAFVVDADVASATLVRAAQGADK
                     QLVTGVTVFDLFEGPSLGEGKKSVAIEITIQPRERTLTDEDLDKIAKSVIANVEKSSG
                     GVLRG"
     gene            complement(395749..396420)
                     /locus_tag="HPDFL43_19892"
     CDS             complement(395749..396420)
                     /locus_tag="HPDFL43_19892"
                     /note="COG3443 Predicted periplasmic or secreted protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164796.1"
                     /db_xref="GI:163757707"
                     /translation="MQNIFIFRYGRALGIACAVLMATMSLAHSPAAAASDKGHTHEAH
                     KSDDIYRGYFEDSQIEDRTLSDWQGDWQSVYPYLLDGSLEPVMAHKAAHGEKSAEEYR
                     AYYQTGYKTDVERITIGGDIFTFYREGKPVAAQYAPDGREVLTYKKGNRGVRYIFRKT
                     AGDDAAPMFVQFSDHAIAPGKAGHYHLYSGNDRAALLEEVTNWPTYYPSGLTADEIVK
                     EMLAH"
     gene            396650..398035
                     /locus_tag="HPDFL43_19897"
     CDS             396650..398035
                     /locus_tag="HPDFL43_19897"
                     /note="COG1488 Nicotinic acid phosphoribosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164797.1"
                     /db_xref="GI:163757708"
                     /translation="MNLILNSDSYKYSHFAQYPPETAAISAYVEARPGGKHDHVLFFG
                     LQMFLKDYLSRRITMNDVDEAEAMITAHGLPFHREGFEKIVTRHNGHLPLLIEALPEG
                     MIAPVGTPLVQVRNTDPDFFWLPTFIETALLRAVWYPSTVATVSHGARQIISASLERT
                     CDTPDEVLPFRLHDFGARGATSAEQAGIGGVAHLVSFMGTDTVSALVYARRFYHEQMA
                     GFSIPAAEHSTMTSWGEDRETEAYRNMLKQFAGPGKLVAVVSDSYDLYRAVKNIWGEE
                     LKAEVEASGGTLVVRPDSGDASRVPVDTVEMLGEIFGFSLNAKGYKVLNPAVRVIQGD
                     GITPETIRVILGRLEDRGWSAENIAFGMGAGLLQKVNRDTLRFAMKANARQDDDGVWH
                     GINKNPKTDPGKASKRYRQAVVVEKGCPLGVALKDIGDRENLMQPVWRDGELLVDWTL
                     TQIRERAASSD"
     gene            complement(398058..398444)
                     /locus_tag="HPDFL43_19902"
     CDS             complement(398058..398444)
                     /locus_tag="HPDFL43_19902"
                     /note="COG2246 Predicted membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical conserved membrane protein"
                     /protein_id="ZP_02164798.1"
                     /db_xref="GI:163757709"
                     /translation="MKRLSFFLFAGAVGFVVDMGVLWLLLELKMLDPFTARAPAIGAA
                     LVCSYIINRTFTFGASHRNVAVEGVRYGGVGLVSTLINYSVYSGLLLLLPGLSPYLAL
                     IFGSGSATLFAYLGYSRFVFGPGPDV"
     gene            398592..399689
                     /locus_tag="HPDFL43_19907"
     CDS             398592..399689
                     /locus_tag="HPDFL43_19907"
                     /note="COG0673 Predicted dehydrogenases and related
                     proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164799.1"
                     /db_xref="GI:163757710"
                     /translation="MNAARVLTGPASGGLECALIRGMADGCQTSAGTGGKNMFRWGIM
                     STAKIGRDQVIPQLQDSENGVVTAIASRDHARARAVADRFGAPYAFSSYEELLSSPDV
                     DGVYIPLPTSQHIEWSIKAARAGKHVLCEKPIALNAAEIAPLIEARDAANVLVCEAFM
                     VTYHPQWHKVRDLIANGAIGRLRHVQGAFSYFNTDPENMRNQPSLGGGGLPDIGVYPT
                     VSTRFSTGREPVRVQATVERDPDFGTDRYASVKADFGDFDLSFYCSTQMALRQIMVFH
                     GEAGYIEVTAPFNAGDYGHAVVTLHNRGHDGAESFRFPGVRQYRLQAEAFVRKVEGAD
                     EEVFTLEQSVLNQKLIDAIYRAATHDGWEQV"
     gene            399887..400594
                     /locus_tag="HPDFL43_19912"
     CDS             399887..400594
                     /locus_tag="HPDFL43_19912"
                     /note="COG0500 SAM-dependent methyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="possible methyltransferase"
                     /protein_id="ZP_02164800.1"
                     /db_xref="GI:163757711"
                     /translation="MNREQTNRIRFAIEELLPPIVRDSVLFTGLARLVWGKHIDTLAD
                     FRVRAPFLTPEEYEALYTEHPRVHDETDNSKACIAEIAKDLTGDSVCDVGCGTGYLLR
                     SLAERRNETPRRYVGVDFVIPEHFSDQGLEFVKAPIEKLPFADGEFDTVICTHVIEHI
                     LDYRKALAELRRIARKRLIIVVPREREAIYTFNPHFNFFPYKHSFLRAIQPLEHRFKC
                     VDIGRDIYFSEERTVPL"
     gene            400594..400947
                     /locus_tag="HPDFL43_19917"
     CDS             400594..400947
                     /locus_tag="HPDFL43_19917"
                     /note="COG0697 Permeases of the drug/metabolite
                     transporter (DMT) superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164801.1"
                     /db_xref="GI:163757712"
                     /translation="MKTSTLMGVIAVPLVISIGQILFKRSSETLSGPDGPIWGLITSP
                     HFWIALVMYGLATVAWVFVIRDMPIGRAYMFMALSYLYIPLLSLLFLSESITTPQIIG
                     ALIICVGIVVSGMKA"
     gene            complement(401054..402064)
                     /locus_tag="HPDFL43_19922"
     CDS             complement(401054..402064)
                     /locus_tag="HPDFL43_19922"
                     /note="COG0463 Glycosyltransferases involved in cell wall
                     biogenesis"
                     /codon_start=1
                     /transl_table=11
                     /product="probable glycosyltransferase protein"
                     /protein_id="ZP_02164802.1"
                     /db_xref="GI:163757713"
                     /translation="MSDGVFEDLDIAVVLPCYNEAETIGAVVAGFRAALPSARIYVYD
                     NNSKDQTALRAALAGATVVRETRQGKGHVVRRMFADIDADVFLMADGDGTYAPDDGPE
                     LIRTLLTERSDMVVGTRRGVTDDAGRRGHAFGNSIFNTLYKTIFGNDFTDIFSGYRAF
                     SRRFAKSFPAVSGGFEIETEMSVHASVLKLPVTELMLDYGRRPEGSQSKLSTFKDGAK
                     ILWMFAMLMKETRPFTFFSYLSVMMLSLSMLFMVPVLNEYFLTGLVTRMPTWMLAVAM
                     MMMSLIIFAGGVILDSVARGRAEQKRFHYMSIAPSPRTGSKPDVVSGKTVKAVAKRRS
                     AA"
     gene            402193..404025
                     /locus_tag="HPDFL43_19927"
     CDS             402193..404025
                     /locus_tag="HPDFL43_19927"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane protein"
                     /protein_id="ZP_02164803.1"
                     /db_xref="GI:163757714"
                     /translation="MGQAGLALEAVAPHSTAFRTLAPLHRPVMLAMLVLTVLTAIMHF
                     SSYVDYVGADNDDVMRLVQVRDLLSGQGWFDLTQTRLGLEGGTLMHWSRLIDLPIASL
                     VFVFSMVMDPVMAEATALFVWPLITVVPIFYALALAGQTLSGASGRVIALLLAFLFVL
                     SVNRFQPGSIDHHNVQLGLVAVIAACLIMPGRPALAHGVAGFAAALAVAIGAETTPHI
                     AVIALIVALQWLWLGEPVRAAALAFSLSMASTLTAVFFATVPQTQYGLVACDALSTGF
                     YALGVVGAGAFFLAAAATSHRSLAFRFAALGLAGAATLGMTLLIAPQCLGNPLAGLDP
                     LLKSMWLDNVTEAQSFMAQLRAEPWTIGGFYAVPVLAMGLCVWNIRKRHQVHAHGVLL
                     VLLLVSWAIALVQVRGSVFANLLSAIPMAALIADLRARANADPKNLRKGLAFAGVSFV
                     AVPFIWAFAGALALMGVDKVMGKEVEGLPTRSENKCADAAAMAPLAQEPTGVVSSPSN
                     LGAHILRFTSHRALSAPYHRNQGGMLTELYAAMARPKDAVKFLRGAGVTVLAYCLSDP
                     QTRTVMAAAPDGLYAELAKGNVPDWLEPVPGTGSAPLQLYRVLP"
     gene            404145..405215
                     /gene="mepA"
                     /locus_tag="HPDFL43_19932"
     CDS             404145..405215
                     /gene="mepA"
                     /locus_tag="HPDFL43_19932"
                     /EC_number="3.4.24.-"
                     /note="COG3770 Murein endopeptidase"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="ZP_02164804.1"
                     /db_xref="GI:163757715"
                     /translation="MSRPLYRIFARYLMALGLTCSLVAPDLGLAISGAQAAETGKPAK
                     QIFGAAKLPAVLPSRAIGFYSKGCLAGGIAIPTDGETWQAMRLSRNRRWGHPDLIALV
                     ERLSREAAAQDGWPGLLVGDISQPRGGPMLSGHASHQMGLDADIWLTPMPERRFSPQE
                     REDVSATSMLKQNTLYVDPDRWTPAHARLLMRAASYPEVERIFVHPGIKKKLCDSWQG
                     DRAAMGKVRPYYGHHYHFHIRIKCPPGATGCKSQTPPPAGSGCGAPLAWWFSDEPWAP
                     AKPKKDTKPKPKKREIRLADLPAACAVVASAPAPASEAEVTLGADPIGRIAASAVEMA
                     PAASAFATLPKVVPLPVWRPRD"
     gene            405371..405748
                     /locus_tag="HPDFL43_19937"
     CDS             405371..405748
                     /locus_tag="HPDFL43_19937"
                     /note="COG1803 Methylglyoxal synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="ZP_02164805.1"
                     /db_xref="GI:163757716"
                     /translation="MTERKAIALIAHDQKKDDLADFARSHRKAMSAYPIVATGTTGGR
                     ILEACPDLDVTRLKSGPLGGDQQIGALIATGEVALVLFFVDPLTAMPHDVDVKALMRL
                     AIVYDVPMALNRATAERLLSTLD"
     gene            405821..406846
                     /locus_tag="HPDFL43_19942"
     CDS             405821..406846
                     /locus_tag="HPDFL43_19942"
                     /note="COG0837 Glucokinase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glucokinase"
                     /protein_id="ZP_02164806.1"
                     /db_xref="GI:163757717"
                     /translation="MPNPSDSDHTIAFPILIGDIGGTNARFAILTDAYAEPKEFPVLA
                     TADFETIDLAIQTGVLDKTSLQPRSAILAVAGPIKDNEIDLTNCDWVIKPEALIRELG
                     FEDVIVINDFEAQALAAASLGQEHLEKVGGGEVRPASSRVVVGPGTGLGVAGLVHARH
                     TWFPVPGEGGHVDIGPRTPRDLELFPLYDTIGGRVSAEQLLCGRGLMNIYRAVCKAGK
                     IKESATSPAEVTAAWSAGSDPAAVEAIELFVTYLGRVAGDLALIFMARGGVYLAGGIV
                     QKIIPALNQPRFREAFEDKAPHNEILENIPTFVITHPLAALHGLAAYARTPVRFGVST
                     KGSRWKA"
     gene            406878..408776
                     /locus_tag="HPDFL43_19947"
     CDS             406878..408776
                     /locus_tag="HPDFL43_19947"
                     /note="COG1132 ABC-type multidrug transport system, ATPase
                     and permease components"
                     /codon_start=1
                     /transl_table=11
                     /product="putative atp-binding abc transporter protein"
                     /protein_id="ZP_02164807.1"
                     /db_xref="GI:163757718"
                     /translation="MKRAGWSSPECGKAPASTGGLIGQGNVARGRNIRDDVESLTMVI
                     RRIIRENGRDYVKTYIFAAFCLVLVAASTAFMAWIMEAVINEAFAKKNADVIWLICGS
                     VLAAFVIRGAASYGQAVALAQVGNNLVARYQQRLIDHLMRLGVGYFGETRSAQIAAQI
                     SQNVAGIRDVMNLTITSFARDLLTLIALIVVMITKDPLLSLIVFVGAPPILIALRYIS
                     KRLRSATRESIDINSRVLSAMQETVQGITIVKAFTMESQISERTSHLIGSAEERSNRI
                     ARLTERTSPLTETVAGLAISGVIAYAAYRSIYDDVLPGAFFSFITALLLAYDPVRRLA
                     RLQINLERAVVNARMIYEILDEEPTQGDRSSAVEIEIPHGEIEFRDVGFAYGNGEKVL
                     DGVSFTAEAGKTTAIVGPSGAGKSTLISLVPRFYDPSSGQVLIDGVDIADVTKGSLRH
                     QIAYVSQQAWLFEGTIRDNLRYARPDATDAEIEDAAKLAHAHDFILGQPQGYDTPLGE
                     NGANLSGGQRQRISIARALVRNAPILLLDEATSALDNESEAAVQKALESAMQHRTVLV
                     IAHRLSTIAKADKIVVMQAGHVVESGSHAELSDTTDGLYARLQAFSETDVVDAGKAKK
                     AKKKGNKS"
     gene            408773..409603
                     /locus_tag="HPDFL43_19952"
     CDS             408773..409603
                     /locus_tag="HPDFL43_19952"
                     /EC_number="1.3.1.26"
                     /note="COG0289 Dihydrodipicolinate reductase"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="ZP_02164808.1"
                     /db_xref="GI:163757719"
                     /translation="MSAMPDSMGLIVVGAAGRMGQSLIRAITEIDGAHLAGAIERPGS
                     AALGKDAGELAGVGPNGVAITDDALTVFAKAEGVLDFTAPAATLEFAELAAQARIVHV
                     IGTTGMGESDEAKLHAASRHARIVKSGNMSLGVNLLSVLVRQAAKALAAGDWDIEVLE
                     MHHRHKVDAPSGTALLLGEAAAEGRDIGLGQHSVRVRDGHTGPREPGTIGFATLRGGS
                     VVGEHSVIIAGEGETVELTHKATDRSIFARGAVRAALWARPQKPGYYSMLDVLGLSDH"
     gene            409648..410283
                     /locus_tag="HPDFL43_19957"
     CDS             409648..410283
                     /locus_tag="HPDFL43_19957"
                     /note="COG0588 Phosphoglycerate mutase 1"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglyceromutase"
                     /protein_id="ZP_02164809.1"
                     /db_xref="GI:163757720"
                     /translation="MSGTLVLVRHGQSEWNLKNLFTGWKDPDLTELGVEEAKTGAQAL
                     KETGLKFDVAFTSNLIRAQRTLDLIMDGIGQTDLPVIRDEALNERDYGDLAGLNKDDA
                     RKKWGEEQVHIWRRSYDVPPPGGESLKDTGARVWPYYMTEILPRVLRGETVLVAAHGN
                     SLRSLLMILDRLDREQILSVNLATGVPMVYKLNADSTVASKEVLGDMSKAH"
     gene            complement(410294..411175)
                     /locus_tag="HPDFL43_19962"
     CDS             complement(410294..411175)
                     /locus_tag="HPDFL43_19962"
                     /note="COG2207 AraC-type DNA-binding domain-containing
                     proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="O6-methylguanine-DNA methyltransferase"
                     /protein_id="ZP_02164810.1"
                     /db_xref="GI:163757721"
                     /translation="MTITAQLDRDITPKNEDYDLVRQTIERISLDFRAQPSLEEIASD
                     LDVAPGKLQKTFSRWAGLTPKAFLQAVTLDHARRLLGHEGLPLLDASYELGLSGPGRL
                     HDLFVTHEAMSPGDFKSGGAGLEIRYGYHPSPFGIALVMATERGLCGLAFADPGEEAA
                     ALEDMARRWPGAVLSADQAATAGYVERVFSPAQWRADQPLRIVMIGTDFQVRVWEALL
                     RIPLGTAKTYSDVATEIGKPSASRAVGAAVGRNPISFVVPCHRALGKSGALTGYHWGI
                     TRKRAMLGWESGCLQSG"
     gene            complement(411254..411721)
                     /locus_tag="HPDFL43_19967"
     CDS             complement(411254..411721)
                     /locus_tag="HPDFL43_19967"
                     /note="COG5488 Integral membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane protein"
                     /protein_id="ZP_02164811.1"
                     /db_xref="GI:163757722"
                     /translation="MNEEPVFEAVLSPHRSLGRNGLIALVAITTALTVAHMFLFAVIG
                     AWPVIGFFGLDLALLFGAFWLSYRSGRTREFVSVSRTDLTVRKVAPSGRAVEHRFNPF
                     WARFNIDRHEEIGITQMQITGEGRRTDVGMFLNPDDKESFASAFQRALATVKR"
     gene            411783..412616
                     /locus_tag="HPDFL43_19972"
     CDS             411783..412616
                     /locus_tag="HPDFL43_19972"
                     /note="COG0177 Predicted EndoIII-related endonuclease"
                     /codon_start=1
                     /transl_table=11
                     /product="probable endonuclease iii protein"
                     /protein_id="ZP_02164812.1"
                     /db_xref="GI:163757723"
                     /translation="MEKPKSPKPAKTPRVSAARAKAPAATAAKTAAAKPRTKPKPKTK
                     RAARRRKNPYSEAEIREIFRRFSVQRPEPKGELEHVNPFTLVVAVALSAQATDAGVNK
                     ATRGLFALADTPEKMLALGEDKVRDLIKTIGLYRNKAKNVIALSQKLVDDFGGEVPRT
                     EAELVTLPGVGRKTANVVRSMAFGIPTLAVDTHVLRIGNRLNIAPGKTPDEVEAAFLA
                     IIPEDYLFHAHHWLILHGRYCCKARKPECERCVIADICKSPEKTVDVPAPLVELPQQI
                     V"
     gene            412624..413364
                     /locus_tag="HPDFL43_19977"
     CDS             412624..413364
                     /locus_tag="HPDFL43_19977"
                     /note="COG0500 SAM-dependent methyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative methyltransferase"
                     /protein_id="ZP_02164813.1"
                     /db_xref="GI:163757724"
                     /translation="MTEPLFHNPDFTRFYDAENPWDTDKEYCLALAKNAGCVLDLGCG
                     TGELATVLADGRRVTGVEPAAAMLDHARRRQGAERVRWVEADARSVRLDETFDLIVMT
                     GHAFQCLLTKDDQQALCATIAAHLAPGGTFIFDSRNPAVEEWRQWTPDQSRRMLDVPG
                     LGEFETWHDARFDHDTAIAAYDTVYCDQRTGQTWQATSRILFASQSQIATAIESAGLK
                     AHRWMGDWTGGPMTETSPEIIPVGGLAG"
     gene            413575..413856
                     /locus_tag="HPDFL43_19982"
     CDS             413575..413856
                     /locus_tag="HPDFL43_19982"
                     /note="COG3609 Predicted transcriptional regulators
                     containing the CopG/Arc/MetJ DNA-binding domain"
                     /codon_start=1
                     /transl_table=11
                     /product="Predicted transcriptional regulators containing
                     the CopG/Arc/MetJ DNA-binding domain"
                     /protein_id="ZP_02164814.1"
                     /db_xref="GI:163757725"
                     /translation="MANVEKISVALTPEMAMTMRQAVESGEYASASEVMREAMREWHA
                     RRTEREQALVQLGRLWDDGVASGEAIDGEAAFERIRQSLDARIGKGGSL"
     gene            413853..414140
                     /locus_tag="HPDFL43_19987"
     CDS             413853..414140
                     /locus_tag="HPDFL43_19987"
                     /note="COG3668 Plasmid stabilization system protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164815.1"
                     /db_xref="GI:163757726"
                     /translation="MSFRLTPRAEADITTIALYIAEDNPAAAVRWYEDMLRHCRNLGE
                     APELGVARPDVRPDLRTFPAGSYMILYRMIAEGAEIVRVVHGARQWQKLLD"
     gene            complement(414185..414961)
                     /locus_tag="HPDFL43_19992"
     CDS             complement(414185..414961)
                     /locus_tag="HPDFL43_19992"
                     /note="COG2981 Uncharacterized protein involved in
                     cysteine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164816.1"
                     /db_xref="GI:163757727"
                     /translation="METGRETATQCQPDSIPAAQKEQPAMIFEAARLAGSNLLLPASR
                     SVLFKSLGLTILLLIGLWFGLGEIFAIMAMPWLDSLLPGLPDWAGWAGTIAAIIAGVG
                     LALVLALFIAPVTAVMAGLFLDEIADVIEVRDYPGETPGRPMPLGQSVKQSLGFLLVV
                     GLGNIVALLLLLVPGINIAAFFLVNGYLLGREYFEFAAMRFMSPADAKRLRARNSTTI
                     FFAGLIIAAFLSVPLLNLLTPMFAAGMMVHLHKMIAGKAG"
     gene            415056..416234
                     /locus_tag="HPDFL43_19997"
     CDS             415056..416234
                     /locus_tag="HPDFL43_19997"
                     /note="COG0456 Acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164817.1"
                     /db_xref="GI:163757728"
                     /translation="MICALEGFATDGCGGLFFSGFSMSAPRIRPAAISDIDALDAIER
                     SVFVSDRISRRSFRTLIDRPTAETIVIETGGEVRGYAMILFRAGAALARLYSLAVAPG
                     QAGKGYGRALLAAAETAAMDHDRILLRLEVREDNAAAIPLYKNAGYRRIGRVADYYED
                     GMAALRFEKLLRGPEAPDVATPFYEQTADFTCGSACLLMALASFRSPEFLDPVWEIRL
                     WREATTVFMLSGPGGCEPFGLAMVAREHGLDPEVWCSTSDMLFLETVRDPEKRRVMEL
                     AQTDFRARVARAGTPVHYEAFGLDWLRARLAEGHVVIILVSGYLMMGKKVPHWVLAHG
                     DDGRHIFVHDPWVEDEWGETAADAANIPLPYAIFDRIACFGRSGLRAAVLIKGKSPDV"
     gene            416227..417684
                     /locus_tag="HPDFL43_20002"
     CDS             416227..417684
                     /locus_tag="HPDFL43_20002"
                     /note="COG0189 Glutathione synthase/Ribosomal protein S6
                     modification enzyme (glutaminyl transferase)"
                     /codon_start=1
                     /transl_table=11
                     /product="RimK-like ATP-grasp"
                     /protein_id="ZP_02164818.1"
                     /db_xref="GI:163757729"
                     /translation="MSDWVILATTLASFDHAATAHKVLTTRDYLARPELFRGARPNII
                     NLSRSYSYQSRGYYASLLAAARGQRVIPSVETIIDLSARKLYENAIPELEDALNKAIS
                     AGPDEAAPARLRVFFGTSADPRFERFCRLLFDWFRAPALEVTIKPGSWSSIPRIALLP
                     LGKFDGADKEVFYAAMARYTARQWKDAKSRAPARFSFATLVDPSEEMPPSTIDSLKHW
                     ARIAARMGVSVEPITRKDLPRLANFDALFIRETTSISNHTYRFARRAQQEGMPVIDDP
                     VSMIRCTNKVYLDELMAANGIPVPPTVMLIGPEDFQRAADQLGFPMVLKVPDSSFSRG
                     VSKVGSMEELRKLAGAWLADSEVLIAQAYMPTSFDWRIGVLGGKPLFAVQYLMAKKHW
                     QIVKHDTGGKPLEGGFKPFTLAQVPPLVLDTGLRAARSIGDGFYGVDLKETDDGVFVI
                     EVNDNPNLEHGVEDAAEKDEVWTRLTNWFIERIEG"
     gene            417895..420756
                     /locus_tag="HPDFL43_20007"
     CDS             417895..420756
                     /locus_tag="HPDFL43_20007"
                     /note="COG2844 UTP:GlnB (protein PII) uridylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="PII uridylyl-transferase"
                     /protein_id="ZP_02164819.1"
                     /db_xref="GI:163757730"
                     /translation="MPNPAENKLRLEEVVDPAVLRASLDTIADNHGGATPAARQAVLA
                     EVKRVNAAGRERARAMLSDDGGGTLCARRICHLQDVITEALYDYASVHVYRVENPSKS
                     ERMTVTAVGGYGRGTLAPGSDIDLLFVLPYKKTPWTEQVVEWILYVLWDMGLKVGHAT
                     RNVDECIRLARSDMTIRTAILEARFLCGEKTLFDNLGARFDKEVVEGTGPEFIGAKLA
                     ERDERHRKAGDTRYLVEPNVKEGKGGLRDLNTLFWIAKYFYHIRDTAELVGLGVLSRR
                     ELALFEKAEDFLWAVRCHMHFLTGKAEERLSFDIQRDIAEGLGYHDHPGLSAVERFMK
                     HYFLVAKDVGDLTRIFCAGLEDQQAKTAPGLSGVMSRFASRPRKIPGTLDFIEDKGRI
                     NLADADVLKRDPVNIIRLFHLADIRELEFHPDALKRVTRSLRLINTELRNDEEANRLF
                     LSMLTSKRHPEIILRRMNEAGVLGRFIPEFGKIVSMMQFNMYHHYTVDEHLLRTVSVL
                     SGIDKGLEEREHPLASKLFPSIEEREALYVAVFLHDIAKGRPEDHSTAGAKVARKLCP
                     RFGLSPNQTELVAWLVEEHLTMSMVAQTRDLNDRKTITDFGEKVRTLERLKMLLVLSV
                     CDIRAVGPGVWNGWKGQLLRTLYYETELMLSGGFSEVSRKERTAHARQALGEALSDWT
                     EKDRKAYLKLHYEPYLLAVPLEEQVRHAAFVRDANKAKKQLATMVRTHAFHAITEITL
                     LSPDHPRLLSIVTGACAAAGANIADAQVFTTSDGRALDTILINRELPDDEDELRRAKS
                     IGRMIEDVLAGKAHIPEVIARKNRGKRKTKPFTVRPQVTISNALSNKFTVIELECLDR
                     PGLLSEITSVLSDLSLDIASAHITTFGEKVVDTFYVRDLVGMKITNENRQTNIVARLK
                     AVLAKEDDELRDQMPPGMIAPHGSTRRTRTTAAKAETGA"
     gene            420753..422318
                     /locus_tag="HPDFL43_20012"
     CDS             420753..422318
                     /locus_tag="HPDFL43_20012"
                     /note="COG0728 Uncharacterized membrane protein, putative
                     virulence factor"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane protein MviN"
                     /protein_id="ZP_02164820.1"
                     /db_xref="GI:163757731"
                     /translation="MSLIGKFASVGSATMASRVLGFVREAMIAAFLGAGPVADAFYAA
                     FRFPNLFRRLFAEGAFNAAFVPLFAKEIEGGGQQAAKRFAEQVLSVLVLTLFALSALA
                     MIFMPFLVGTVIAPKFAGDPAKFDLTVQLARIMFPYLAAMSLVAMLAGILNSLRRYFL
                     AALAPVLLNIVLVSGLIMSGYLDLAAPQIGVVLGWSVTISGVLQLGLLVWALMREGFT
                     LGLVRPRLTPAVRRLLWLALPAAVTGGITQINLLVGQIIASGQAGAIAVINYADRLNQ
                     LPLGVIGIAIGVVLLPELSRALRAGDAKEAQHLQNRSLEFGLAITVPAAVGLALLPEP
                     IIALVFERGAFTRETTLLTSTVLAAFALGLPAFVLTKIFTPAFYAREDMRTPLWASVV
                     SVVLNIAGSLILFPRLGVTGIAIATSFAGWVSVLFLGQRLVSGGLFRPSGQTVKRIGL
                     ILVAAALMGSLLWWVEASFPQFLLEGTLLVRLVSVFITVIAAVTVYFGFAFLTGGLDR
                     AEFARLFKRRKSV"
     gene            422429..423493
                     /locus_tag="HPDFL43_20017"
     CDS             422429..423493
                     /locus_tag="HPDFL43_20017"
                     /EC_number="6.1.1.2"
                     /note="COG0180 Tryptophanyl-tRNA synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanyl-tRNA synthetase"
                     /protein_id="ZP_02164821.1"
                     /db_xref="GI:163757732"
                     /translation="MTATFKPQVFSGVQPTGNLHLGNYLGAIRKFVALQNEHDCIFCV
                     VDLHSITAQLVHEDLKAQTRSIAAAFIASGIDPVKHIVFNQSAVSGHAELAWIFNCVA
                     RIGWMNRMTQFKDKAGKDRENASLGLLAYPSLMAADILLYRATHVPVGDDQKQHLELT
                     RDIAQKFNIDFSDRIKAAGLGVDMMVGEEKVTGFFPMTEPLIDGPAPRVMSLRDGSRK
                     MSKSEPSDLSRINMTDDADTIVKKIRKAKTDPAPLPETLDELKGRPEADNLVAIYAAL
                     SDRTREDVIAEYGGQQFSVFKPALAELAVTVLAPITGEMQRLMDDPSHIDAILKDGSE
                     RANVIAHNTMRDVREIIGFL"
     gene            423548..424039
                     /locus_tag="HPDFL43_20022"
     CDS             423548..424039
                     /locus_tag="HPDFL43_20022"
                     /note="COG0589 Universal stress protein UspA and related
                     nucleotide-binding proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164822.1"
                     /db_xref="GI:163757733"
                     /translation="MVSRRRSREAGHRRKFLAVIDDTPECERAMRYAGMRAHNSGGGL
                     VLVYVIEPGDFQHWLGVEEIMRAEAMEEAEATLAKASEKMRQLIGIDPEVVIRQGNTT
                     EEIHAAIEEDQDIAILVLAAGSAKDGPGPLVASIAGRGAAFPIPVTVIPDALSDDEID
                     ALS"
     gene            424162..424725
                     /locus_tag="HPDFL43_20027"
     CDS             424162..424725
                     /locus_tag="HPDFL43_20027"
                     /note="COG0694 Thioredoxin-like proteins and domains"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164823.1"
                     /db_xref="GI:163757734"
                     /translation="MFIQTESTPNPATLKFLPGKVVMQSGTADFRDAEEAGATSQLAG
                     KLFGIPGVIGVFYGYDFITITKDDADWQHLKPAILGTIMEHFMSGAPVMSGPVGEVPE
                     GEEEFFESGDETIVATIKELLESRVRPAVAQDGGDITFRGFRDGKVFLHMKGACAGCP
                     SSTATLKHGIQNLLRHFVPEVREVEAV"
     gene            424874..425554
                     /locus_tag="HPDFL43_20032"
     CDS             424874..425554
                     /locus_tag="HPDFL43_20032"
                     /note="COG1214 Inactive homolog of metal-dependent
                     proteases, putative molecular chaperone"
                     /codon_start=1
                     /transl_table=11
                     /product="probable O-sialoglycoprotein endopeptidase
                     protein"
                     /protein_id="ZP_02164824.1"
                     /db_xref="GI:163757735"
                     /translation="MLTLAIDCSAIHCAVAVHASDGDRILGEQCPAIGRGHAEQLPGI
                     LQSVLDAAGVELSAIERIGVTVGPGSFAGIRVGVAFARGLALTLGIPCVGVGSLEAMA
                     IPAALTSARPVMAVLDARRDRVWTLVAAADSSILEPGCELTPEAAARLAADVGCDIVG
                     SGGPLLAAIDPGLADRHIGNRIAPDIAEVARLAARLDPADNPPEPRYLREADAKPQTG
                     FALPHATV"
     gene            425560..426048
                     /locus_tag="HPDFL43_20037"
     CDS             425560..426048
                     /locus_tag="HPDFL43_20037"
                     /note="COG0456 Acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-protein-alanine N-acetyltransferase
                     protein"
                     /protein_id="ZP_02164825.1"
                     /db_xref="GI:163757736"
                     /translation="MFGLFSRSPECLILEVEMKDAATLSHIHGEAFARAWGDGEFESL
                     TSQASVFGYLACPEGRARDRAGGFVLCREAAGEAEILSIGILNAHRRAGLGWRLMRSA
                     LQEAVRRGAEEMFLEVDETNLAAIQLYNRLGFVKVGERRAYYKQDNAESTTALVMRRD
                     LR"
     gene            426138..426581
                     /locus_tag="HPDFL43_20042"
     CDS             426138..426581
                     /locus_tag="HPDFL43_20042"
                     /note="COG0735 Fe2+/Zn2+ uptake regulation proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="ferric uptake regulator"
                     /protein_id="ZP_02164826.1"
                     /db_xref="GI:163757737"
                     /translation="MDELKPLDEQKPLEDRCAERGMRMTEQRRVIARVLDGADDHPDV
                     EELHRRAVEVDPRISMSTVYRTVKLFEDIGIIERHDFRDGRSRYETVPEEHHDHLIDL
                     RTGQVIEFHSPEIEALQERIAREHGFRLVDHRLELYGVPLKGDKR"
     gene            426627..427424
                     /locus_tag="HPDFL43_20047"
     CDS             426627..427424
                     /locus_tag="HPDFL43_20047"
                     /note="COG0204 1-acyl-sn-glycerol-3-phosphate
                     acyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="ZP_02164827.1"
                     /db_xref="GI:163757738"
                     /translation="MIATLRIVVVAAAFLIVTLSLLPVQLAALAAGHSLMRRLPRLWH
                     RIMCRIIGLKVVVHGRLSAERPLLIVSNHISWKDIMVLGSVADVVFIAKFEVRQWPVF
                     GWLARLQRSVFVDRARPREVGVQTSEVSERLLAGEAVVLFAEGTTSDGNRVMPFKSSL
                     FGAASAALPRAPDNTVHIQPVAIAYTGIHGLPMGRYHRPVASWPGDVALVPHLLGVLR
                     EGALEVDVVFGETIAFDAAADRKKTARHVEAQIRSAVAAALRGTLPD"
     gene            427468..428910
                     /locus_tag="HPDFL43_20052"
     CDS             427468..428910
                     /locus_tag="HPDFL43_20052"
                     /note="COG0621 2-methylthioadenine synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA modification enzyme, MiaB family protein"
                     /protein_id="ZP_02164828.1"
                     /db_xref="GI:163757739"
                     /translation="MTQATPTSLTRAGQPADAGTATKKVFVKTYGCQMNVYDSERMGD
                     ALSRDGYQPVDSVEAADLVLINTCHIREKAAEKVYSQLGRLAQLKKRRNSEGGDLMVA
                     VAGCVAQAEGEEMIRRAPVVDVVIGPQTYHRLPGALAKARNGERVVETEFPTEDKFDR
                     LPDASAGTIRTRGVTAFLTVQEGCDKFCTFCVVPYTRGAEVSRPVERIMSEAERLAAA
                     GVREVTLLGQNVNAWHGQGSDGREWGLGELVHRLAAIEGIDRIRYTTSHPRDMDDALI
                     NAHRDLPELMPYLHLPVQSGSDRILKAMNRRHTAAEYIRLVERIRMARPDIALSGDFI
                     VGFPGETDEDFEDTMRLIREVNYAAAFSFKYSIRPGTPGAGMDGQVDEAVKSERLTRL
                     QALINEQTRDFGRQCVGKTADLLLEKPGRNTDQLVGRSPWLQPVIVDAKAGKIGDIVN
                     MRIMQTGSNGLYAEPVETQSGNQGAISFDS"
     gene            428900..429946
                     /locus_tag="HPDFL43_20057"
     CDS             428900..429946
                     /locus_tag="HPDFL43_20057"
                     /note="COG1702 Phosphate starvation-inducible protein
                     PhoH, predicted ATPase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164829.1"
                     /db_xref="GI:163757740"
                     /translation="MTAEHLSQTDAGAPTSGASDATHVALTFENNRLASELFGQFDQN
                     LALIEQKLKVDARSRGNTVSLRGEEIATNQARRALDHLYDRLLKGSTVEASDVEGAIR
                     MALAADDQLVLPTLERKGKLALAQISTRKKTVMARTPTQDAYMRAMERAELVFGVGPA
                     GTGKTYLAVAYAAQLLERGSVERIILSRPAVEAGERLGFLPGDMKEKVDPYLRPLYDA
                     LYDMMPGDKVERAITAGVIEIAPLAFMRGRTLANAAVILDEAQNTTQMQMKMFLTRLG
                     ENSRMIITGDPSQVDLPRGVTSGLVEALSILDGVDGVVTCRFREVDVVRHPLVQRIVE
                     AYGRKEHPKADSTS"
     gene            429943..430458
                     /locus_tag="HPDFL43_20062"
     CDS             429943..430458
                     /locus_tag="HPDFL43_20062"
                     /note="COG0319 Predicted metal-dependent hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164830.1"
                     /db_xref="GI:163757741"
                     /translation="MIPEPLFSLALALEAGEWGDEARIEALAQTALEAAAADLTRNEA
                     QPFPSEPPEVSLVLADDAMMTGINSEWRAQAKPTNVLSFPAFPLTPGAMPGPMLGDII
                     LARETIEREAGDLGKPVDEHITHLVVHGFLHLFGYDHIQNEDAEKMEAIETRILTSLN
                     LSDPYGDIEPV"
     gene            430472..431632
                     /locus_tag="HPDFL43_20067"
     CDS             430472..431632
                     /locus_tag="HPDFL43_20067"
                     /note="COG1253 Hemolysins and related proteins containing
                     CBS domains"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164831.1"
                     /db_xref="GI:163757742"
                     /translation="MTDSNAMAAAPAKSGDANSATSASSTEDTDSYLPVPVPAAPDER
                     NGTGLWQRLSRALFPPSDRETIREDLTDALKSGGELHEAFSADERAMLHNILRLREVR
                     VEDVMVPRAEIEAVDQATTLGHLLEIFEESGRSRMPVYADNLDDPRGMIHIRDLLAWI
                     TKQARAKRRPSAKGASAAALKRTSLNALELSRVDLSKTLQESGITRKVLFVPASMLAN
                     DLMQRMQANRTQMALVIDEYGGTDGLVSLEDIVEMVVGDIADEHDDEEETLISKTGDD
                     IWVVDAKAELDDIAKEIGPDFDVREQSEDVDTIGGLIFSELGRVPARGEVVQALPGFE
                     FHVTDADPRRVKRVRIVRKRLGARRRPARSETPSKKAAPVKKVVEPDDASAA"
     gene            431902..433458
                     /locus_tag="HPDFL43_20072"
     CDS             431902..433458
                     /locus_tag="HPDFL43_20072"
                     /note="COG0815 Apolipoprotein N-acyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane acyltransferase"
                     /protein_id="ZP_02164832.1"
                     /db_xref="GI:163757743"
                     /translation="MCWGGKRILLSMFAGALAVLALPPFNFFAVLFVSFPILVWLLDG
                     AIGPAEAGPVGRLRPAFLTGWWFGFGYFVAGLWWLGNALLIEADSFAWALPIAVLGLP
                     AVLAVFYGVAAAAARLLWSDGLGRIAALSAAFGLAEFARAFVLTGFPWNAIGYAAMPT
                     PLMMQSSEIVGIYGMSALAVFVFSAPALIGTRRGAVPGILIALVLFCTHAGYGLVVLS
                     QNGTTRPIHDGAVIRIVQPAIDQSAKWDIAERERIFSNLLQLSALPQKEGAPRPTHII
                     WPETALPFLLTENPGALSRMADMLQVGQTLITGAVRQEDGVGGTTRRFYNSMYAIDDE
                     GQIIGSADKAHLVPFGEYLPFEALLRRFGLTPVAESFGGFSGAERRGLLSLPGGLNAI
                     PLICYEAIFPRLAEIDGEPGALLLNLTNDAWYGFTPGPYQHLRQAQLRAVETRLPLVR
                     AANNGISVVTDSFGRIVGSLPLGDAGVFDVELPAAGVSLWHNGSRLITFGLIIGIMVL
                     LTLVARRGKS"
     gene            433621..434040
                     /locus_tag="HPDFL43_20077"
     CDS             433621..434040
                     /locus_tag="HPDFL43_20077"
                     /note="COG1396 Predicted transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="dna-binding protein"
                     /protein_id="ZP_02164833.1"
                     /db_xref="GI:163757744"
                     /translation="MIENKKKPNPIDIHVGSRIRLRRTMLGMSQEKLGEALGITFQQI
                     QKYEKGTNRVGASRLQNISTILNVPVSFFFEDAPGDPATGQPGMAEANSSNYVVDFLS
                     SSEGLQLNRAFIKIPDPKVRRRLVDLVKSLASDPETD"
     gene            434292..435533
                     /locus_tag="HPDFL43_20082"
     CDS             434292..435533
                     /locus_tag="HPDFL43_20082"
                     /note="COG0192 S-adenosylmethionine synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="ZP_02164834.1"
                     /db_xref="GI:163757745"
                     /translation="MERSTFLFTSESVSEGHPDKVCDRISDEIVDLVYREAKKAGVDP
                     WSVRVACETLATTNRVVIAGEVRVPPSLVKKDKAGKDVINPSKFKSAARKAIKAIGYE
                     QDGFHWKTAKIDVLLHFQSAHIAQGVDNAADHQGSEGAGDQGIMFGYACNETPELMPA
                     PIYYSHKILELLAAARHKGEGDAGKLGPDAKSQVTVRYVDGKPSEVTSIVLSTQHLDG
                     SWDSAKVRKVVEPYIREALEGLSIADDCKWYINPTGKFEIGGPDGDAGLTGRKIIVDT
                     YGGAAPHGGGAFSGKDTTKVDRSAAYAARYLAKNAVAAGFADRCTIQLSYAIGVAQPL
                     SINVNFHDTGKVSETALEEALPKVMDLTPRGIRTHLDLNKPIYARTAAYGHFGRKAGR
                     DGSFSWEKLDLVKPLKAAIKG"
     gene            435559..436263
                     /gene="trmB"
                     /locus_tag="HPDFL43_20087"
     CDS             435559..436263
                     /gene="trmB"
                     /locus_tag="HPDFL43_20087"
                     /EC_number="2.1.1.33"
                     /note="COG0220 Predicted S-adenosylmethionine-dependent
                     methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N(7))-methyltransferase"
                     /protein_id="ZP_02164835.1"
                     /db_xref="GI:163757746"
                     /translation="MTEPTRRSRATEAFYGRRRGKSLKSAQADALTRRLPELKLDLSL
                     PAPRDIKSLWPGRVEEVRLEIGFGGGEHLLHRAASNPQTGFIGVEPFVNSMAKMLTSL
                     DADGLTNIRVYDDDATQVLDWLPDAVLDRIDLLYPDPWPKMKHWKRRFVSTVNLDRFA
                     RVLKPGGRFCFASDIDTYVNWTLTHIAAHPEFEWTAKTARDWREPWSGWPGTRYEAKA
                     IREGRTPAYLEFVRLS"
     gene            436484..437101
                     /locus_tag="HPDFL43_20092"
     CDS             436484..437101
                     /locus_tag="HPDFL43_20092"
                     /note="COG0779 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164836.1"
                     /db_xref="GI:163757747"
                     /translation="MTDNAASAYEPRLVTETGVDARIAEIVEPVLASIDMRLVRVRLS
                     GQNGLTLQIMAERTDGTMTVEDCEAASRALSPVLDVEDPVEKAYHLEISSPGIDRPLV
                     RKSDFERWQGHLARCDASVLINGRKRFRGFIRDVSDTGFIVERDQPVYGEENRAEIPF
                     SALAEAKLVLTDELIRESLRADKAARDAANDDDTGKDPSQDEDLA"
     gene            437196..438848
                     /gene="nusA"
                     /locus_tag="HPDFL43_20097"
     CDS             437196..438848
                     /gene="nusA"
                     /locus_tag="HPDFL43_20097"
                     /note="COG0195 Transcription elongation factor"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor NusA"
                     /protein_id="ZP_02164837.1"
                     /db_xref="GI:163757748"
                     /translation="METDMAVSANRLELLQIADAVAREKSIDREIVIAAMADAIQKAA
                     RSRYGSESNIRADINAKTGEIKLQRLLEVVEHAEDYSTQIPLMLARDRNPDAQLGDFI
                     ADPLPPMDFGRIAAQSAKQVIVQKVREAERDRQFDEFKDRIGEVVNGTVKRVEYGNVI
                     VDLGRGEGIVRRDETIPREAFRYGDRIRAYVYDVRREQRGPQIFLSRTHPQFMVKLFT
                     MEVPEIYDGIIEIRSVARDPGSRAKIAVISNDSSIDPVGACVGMRGSRVQAVVGELQG
                     EKIDIIPWSPSPATFIVNALQPAEVAKVVLDEDAERIEVVVPDEQLSLAIGRRGQNVR
                     LASQLTGWDIDILTEEEESQRRQKEFNERTQLFMEALDVDEMVGQVLASEGFSQVEEV
                     AYVDLGEITAIEGFDDETAEELQTRAREYLDKVEAELDAKRKELGVEDELRSIAGMTT
                     AMMVALGGDEIKTVEDFAGCAVDDLTGWSERKDGETKRFDGLFTGMDITRAEAESMIL
                     SARLAVGWITEDELQAEEADSEDEAEAEGEAETEVASGGEGA"
     gene            438871..439503
                     /locus_tag="HPDFL43_20102"
     CDS             438871..439503
                     /locus_tag="HPDFL43_20102"
                     /note="COG2740 Predicted nucleic-acid-binding protein
                     implicated in transcription termination"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164838.1"
                     /db_xref="GI:163757749"
                     /translation="MSVKVRIEPVNDRMCIVTRERGQPDGLLRFVAGPDGQLIPDLRL
                     NLPGRGCWVTAEREKVELAVKRKLFGRALKTEVIVDPDLGAAVEGLLCASLLGMMNMA
                     RKSGQFISGSGKVEEAVRSGAAIALMHASDAAEDGIRKLRQANTARAKGDRQAQIPVF
                     RLFSAEELSLAMGEGGFIHAAALAGQAGEGVVKRAMILARYRYGPDKGVD"
     gene            439598..442210
                     /gene="infB"
                     /locus_tag="HPDFL43_20107"
     CDS             439598..442210
                     /gene="infB"
                     /locus_tag="HPDFL43_20107"
                     /note="COG0532 Translation initiation factor 2 (IF-2;
                     GTPase)"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="ZP_02164839.1"
                     /db_xref="GI:163757750"
                     /translation="MSDSKDDKTISVTGKKTFSLKRPSVEQGMVRQEMGRGRTKAVVV
                     ETRKRRINRPEDEKPAQPVTLKPRAAPAPEKAVEKPAAPAPAPKPAPAAPARGGVVLN
                     ELSASEVEARRRALQDSRVRDVEDRKRAEEEAARRAEEEARRAVEEAEQAKARAEQEA
                     RLAKEAEERKQAEEEAAQNAPVEAVVPPPPPPAEDAAARGRRREPGDAAPARSGAPAR
                     PGAKVTRPETPKPSRTKGEDDRRRGKLTLTAALNDDGNSRGRSLSAMRRRQEKMRRSM
                     MQETREKIAREVTLPETITIQELSQRMAERSVDVIKYLMKEGQMMKPGDVIDADLAEL
                     IAGEFGHTVKRVSESDVELGIFGADKGDEGELKPRPPVVTIMGHVDHGKTSLLDAIRN
                     ANVVSGEAGGITQHIGAYQVEKNGQLITFIDTPGHAAFTAMRARGAQATDIAILVVAA
                     DDAVMPQTIESINHAKAAEVPIIVAINKIDKPTADAQKVRTDLLQHEVFVESMGGEVL
                     DVEVSALKQLNLDKLLDAILLQAELLDLKANPDRTAEGVVIEAKLDRGRGSVATVLVQ
                     AGTLTPGEILVAGDQWGRVRALVNDRGEQVKSAGPAFPVEILGLQGTPQAGDRFAVVE
                     NEGRAREIAEYRQRLARDKAAARQSGSRGSLEQMMTQLQDTGSQEFPLLVKGDVQGSI
                     EAIAGAIEKLGTDEVRARIIHSGAGAITESDISLAEASGAAIIGFNVRANKQARDAAE
                     RDGVEIRYYNIIYDLVDDVKAAMSGMLSPERRETFLGNAEILEVFNITKVGKVAGCRV
                     TEGKVERGAGVRLIRDSVVIHEGKLKTLKRFKDEVAEVNGGQECGMAFENYEDIRAGD
                     VIECFRVEHVTRTL"
     gene            442301..442747
                     /locus_tag="HPDFL43_20112"
     CDS             442301..442747
                     /locus_tag="HPDFL43_20112"
                     /note="COG0858 Ribosome-binding factor A"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="ZP_02164840.1"
                     /db_xref="GI:163757751"
                     /translation="MSKPTTSAPSQRMLRVGEQVRAAITQVLQRGDIRDPILSNTLIS
                     VTEVRMSPDLQVATAYVTPLGVEDHAATIAALNKNARFIRGRISPDLRQMRNIPELRF
                     RDDTSFENYSKIDALLRSPEVARDLDHDEDADGTTENPDSQGEGKS"
     gene            442749..443684
                     /locus_tag="HPDFL43_20117"
     CDS             442749..443684
                     /locus_tag="HPDFL43_20117"
                     /note="COG0130 Pseudouridine synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine synthase B"
                     /protein_id="ZP_02164841.1"
                     /db_xref="GI:163757752"
                     /translation="MGRRGKKKGRPISGWLVLGKPWDFGSTEAVSKIKWLFKADKAGH
                     AGTLDPLASGMLPIALGEATKTVPYVMDGRKIYEFTVAWGEQRTTDDLEGEVTESSDQ
                     RPGRAAIEALLPNYTGVIEQVPPAFSAVKIAGERAYDMARSGEVVEIPSREVEIHRIT
                     LLSCPDPDHAIFEVECGKGTYVRALARDFGRDLGCFGHISALRRTMVVPFSEDQMVPL
                     ADLTALEEIEDDAERLAALDAFLVPAGEALAGLPRIDISGDQAHRLRMGNPIILRGRD
                     APVATDDACAFNAGVLVAIGEVAGGEFRPRRVFKA"
     gene            443832..444164
                     /locus_tag="HPDFL43_20122"
     CDS             443832..444164
                     /locus_tag="HPDFL43_20122"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164842.1"
                     /db_xref="GI:163757753"
                     /translation="MAALFALAAAAIMSPVSASAQTPGYDGNGCGWYIILGCSASRAD
                     AQQTLRQLGGPMVGGGAGSRVLNTSDVDGFRNGFYCVADGPYVSEADAASVAWIEAVP
                     DAYVKRGC"
     gene            complement(444176..445276)
                     /locus_tag="HPDFL43_20127"
     CDS             complement(444176..445276)
                     /locus_tag="HPDFL43_20127"
                     /note="COG2367 Beta-lactamase class A"
                     /codon_start=1
                     /transl_table=11
                     /product="putative beta-lactamase"
                     /protein_id="ZP_02164843.1"
                     /db_xref="GI:163757754"
                     /translation="MEIERLEQVFGAPTLEETLFSARFLMAVPTKRLQSIIRDVEDRY
                     GEMLSVRQDSERYLVETETHSIPVEIKLDQDGLIVGLLIKPAEPKTASFEETLAAIAA
                     TPGEVSYLVRRENVPDFALSAERRLAVGSAFKLGVLAVLMDDLNAGRRSWDDVMRLEE
                     RDRSLPSGRLQDFPSGAPFTLHTLAAAMIAESDNTATDMLIRLLGRDRIAERLGLNTL
                     LTTRAFFHLKADPELAARYAAGNSQERLILLEDLEWRKLPEVEDVTGPHHQGVEWYVP
                     VEQLCELAIEVAHLDIFTLNPGPVRTANWNRVAYKGGSEPGVLNLTAALRHADGDTSC
                     ISVSVNAETPIDETAVSSLFARLASQLSEPLP"
     gene            445649..445918
                     /gene="rpsO"
                     /locus_tag="HPDFL43_20132"
     CDS             445649..445918
                     /gene="rpsO"
                     /locus_tag="HPDFL43_20132"
                     /note="COG0184 Ribosomal protein S15P/S13E"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="ZP_02164844.1"
                     /db_xref="GI:163757755"
                     /translation="MSITAERKAALIEEYATTPGDTGSPEVQVAILTERINNLTGHFK
                     DNKKDNHSRRGLLKMVSTRRSLLDYVKGKNHERYATLIARLGIRR"
     gene            446254..448374
                     /locus_tag="HPDFL43_20137"
     CDS             446254..448374
                     /locus_tag="HPDFL43_20137"
                     /note="COG1185 Polyribonucleotide nucleotidyltransferase
                     (polynucleotide phosphorylase)"
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide phosphorylase/polyadenylase"
                     /protein_id="ZP_02164845.1"
                     /db_xref="GI:163757756"
                     /translation="MFDTHKVEIEWGGRPLILETGKVARQADGAVIATYGETVVLATV
                     VSAKSPKPGQDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSENETLTSRLIDRPLRPL
                     FPDGYKNDTQIIITVMQHDLENNPDILALVAASAALTISGIPFMGPIAGARVGYINGE
                     YVLNPHVDEMPESDLDLVVAGTNDAVLMVESEAKELAEDVMLGAVMFGHKSFQPVIDA
                     IIKLAEAAAKEPRDFSAPDHSDLEAEMLSMCEADLRKAYENTDKAARYAAIDEVKAKV
                     KEHFAPAEGEEPRFTSEVIGAVFKSLQAKVVRGAILETKSRIDGRDLSTVRPIVSEVG
                     LLPRTHGSALFTRGETQAIVVATLGTGEDEQYVDSLTGTKKATFMLHYNFPPYSVGET
                     GRTGSPGRREIGHGKLAWRAINPMMPSAEQFPYTLRVVSEITESNGSSSMATVCGTSL
                     ALMDAGVPLAKPVAGIAMGLIKEGEDFAVLSDILGDEDHLGDMDFKVAGTADGITALQ
                     MDIKIDGITEEIMKIALSQAEGGRLHILKEMGNALTESRGQLGEFAPRIEVMNIPVDK
                     IRDVIGTGGKIIREIVEKTGAKINIDDDGTIKIASSSGKEIEAAKKWIHSIVAEPEVG
                     VIYEGTVVKVADFGAFVNFFGPKDGLVHISQLAAERVAKTSDVVKEGQKVWVKLLGFD
                     ERGKVRLSMKVVDQETGKEVTGDE"
     gene            complement(448677..449486)
                     /locus_tag="HPDFL43_20142"
     CDS             complement(448677..449486)
                     /locus_tag="HPDFL43_20142"
                     /EC_number="1.3.1.10"
                     /note="COG0623 Enoyl-[acyl-carrier-protein] reductase
                     (NADH)"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-(acyl carrier protein) reductase"
                     /protein_id="ZP_02164846.1"
                     /db_xref="GI:163757757"
                     /translation="MTGIMKGKRGLIMGVLNNHSIAWGIAQQLAEAGAELAFTYQAEA
                     FEKRVRPLAESVGSKLLLPCDVEDVASVDAVFDTLKAEWGTIDFVVHAIGFSDKSELK
                     GRYADVTTRENFSRTMVISAYSFTEVAQRAAPLMSEGGSILTLTYGGSMRVMPNYNVM
                     GVAKAALEAMVRYLAADYGQDGIRVNAISAGPVRTLAGAGIGDARAMFNYQKKNAPLR
                     RTVDIGDVGKSALYLLSDLSSGVTGEIHYVDSGFNITSMPIVDELKKADEG"
     gene            complement(449492..450715)
                     /locus_tag="HPDFL43_20147"
     CDS             complement(449492..450715)
                     /locus_tag="HPDFL43_20147"
                     /EC_number="2.3.1.41"
                     /note="COG0304 3-oxoacyl-(acyl-carrier-protein) synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-(acyl carrier protein) synthase"
                     /protein_id="ZP_02164847.1"
                     /db_xref="GI:163757758"
                     /translation="MRRVVVTGMGIVSSIGNNASEVTESLRNAKSGISFSQDFADHGF
                     RSHVWGAPTLDPTELVDRRAMRFLSRGGAWNHVAMQQAIDDAGVSEADITNERTGIVM
                     GSGGPSTRTLIDAADITRKNGSPKRIGPFAVPKSMSSTASATLATWFKIHGVNYSISS
                     ACSTSAHCIGNAAELIQWGKQDMMFAGGHEDLDWTMSNLFDAMGAMSSKYNESSPATA
                     SRAYDTTRDGFVIAGGAGVLVLEELEHAKARGAKIYAELTGYGATSDGYDMVAPSGEG
                     AVRCMRQALATVKGRVDYVNTHGTSTPVGDSKEIGAIREVFADDLPYVQSTKSLTGHS
                     LGAAGAQEAIYSLLMMQEGFVGESAHITELDPEFDGVPIVRERIDDAKIDTALSNSFG
                     FGGTNATLVFQRHDR"
     gene            complement(450795..451310)
                     /locus_tag="HPDFL43_20152"
     CDS             complement(450795..451310)
                     /locus_tag="HPDFL43_20152"
                     /note="COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl
                     carrier protein) dehydratases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative
                     3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
                     (Beta-hydroxydecanoyl thioester dehydrase)"
                     /protein_id="ZP_02164848.1"
                     /db_xref="GI:163757759"
                     /translation="MVDRQSSYSYDELIKCAEGDLFGPGNAQLPLPPMLMVSRITDIS
                     ETGGEFDKGYLRAEFDITPDLWFFPCHFKGNPVMPGCLGLDGMWQLTGFYLGWLGEEG
                     RGMALSTGEVKFKGMVTPEVKKLEYGIDFKRVMRGRLVLGIADGWLKADGETIYNASD
                     LKVGLAKDKTA"
     gene            451571..452002
                     /locus_tag="HPDFL43_20157"
     CDS             451571..452002
                     /locus_tag="HPDFL43_20157"
                     /note="COG0735 Fe2+/Zn2+ uptake regulation proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="putative iron response regulator protein"
                     /protein_id="ZP_02164849.1"
                     /db_xref="GI:163757760"
                     /translation="MHSATRSKTADRDSALRLRDAGLRPTRQRVALADLLFAKGDRHL
                     TAEELHEEAVSVGVPCSLATVYNTLHQFTEAGMLRVLSLETAKTYFDTNVSDHHHFVV
                     EGSNNVLDIPVGNISVSDLPEAPEGMEITHVDVVIRVRPKR"
     gene            452254..454098
                     /locus_tag="HPDFL43_20162"
     CDS             452254..454098
                     /locus_tag="HPDFL43_20162"
                     /EC_number="4.2.1.9"
                     /note="COG0129 Dihydroxyacid dehydratase/phosphogluconate
                     dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="ZP_02164850.1"
                     /db_xref="GI:163757761"
                     /translation="MPPYRSRTSTHGRNMAGARSLWRATGMKDGDFGKPIIAVVNSFT
                     QFVPGHVHLKDLGQLVAREIEKAGGIAKEFNTIAVDDGIAMGHDGMLYSLPSREIIAD
                     SVEYMVNGHCADAMVCISNCDKITPGMLNAAMRLNIPAVFVSGGPMEAGKVVLENGVA
                     KSVDLVDAMVLAADDSVSDADVMTMEQNACPTCGSCSGMFTANSMNCLTEALGLALPG
                     NGSTLATHKDRERLFVEAGHLIVDLARRYYEQDDATALPRSIASFAAFENAMTLDISM
                     GGSTNTVLHLLAASHEGEVGFTMDDIDRLSRKVPVLCKVAPAVENIHMEDVHRAGGIF
                     GILGELDRAGLIDSSLPTIHSATMKQALAGWDIVQTDSEAVHKFYSAAPGGVPTQTAF
                     SQERRYEEGVDLDRKTGVIRARDHAYSQDGGLAVLFGNIALDGCIVKTAGVDESILKF
                     TGPARIFESQDSAVSAILTGKVKPGAVVLIRYEGPRGGPGMQEMLYPTSYLKSKGLGK
                     VCALVTDGRFSGGSSGLSIGHVSPEAAEGGAIGLVEEGDTIVIDIPNRVMKVDLPDSV
                     LADRRAAMEARGADAWKPSEKRKRKVTTALKAYAAMTSSAAKGAVRIV"
     gene            complement(454168..454731)
                     /locus_tag="HPDFL43_20167"
     CDS             complement(454168..454731)
                     /locus_tag="HPDFL43_20167"
                     /note="COG3807 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164851.1"
                     /db_xref="GI:163757762"
                     /translation="MRRLSLLAASCLVLAATTIVPSGPFCPSGVGVAHAQSAGKGPSG
                     LPLPRFVSLKATRVNLRIGPGRDYAVAWLYTRPGVPMEVIQEYDNWRRVRDAEGTEGW
                     VYQSLLSGERTATVAPWKAASGKDEFTSMHREARANARVVARLEPGVVVKVKACDGEW
                     CEASAEGMDGYVAQSQIWGAYPGEAFR"
     gene            455006..456010
                     /locus_tag="HPDFL43_20172"
     CDS             455006..456010
                     /locus_tag="HPDFL43_20172"
                     /note="COG1052 Lactate dehydrogenase and related
                     dehydrogenases"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="ZP_02164852.1"
                     /db_xref="GI:163757763"
                     /translation="MPNRKKPKVYITRRLPDQVETRMRELFDAELNITDEPRAQPELV
                     AAMRSADVLVPTVTDKIDAALIEQAGPQMKLIANFGNGVDNIDVDAAQKKGITVTNTP
                     NVLSDDTADMTMALMLAVPRRLTEGANVLVGNDGSWKGWSPTWMLGHRIGGKRLGIIG
                     MGRIGTAVARRAKAFGLSIHYHNRRRVDPDTEDQLEATYWDSLDQMLARVDIVSVNCP
                     STPATFHLLSARRLELMKPGAYIVNTARGGIIDEDALIKALREGRLSGAGLDVFEHEP
                     AVDKRLVKLASEGRVVLLPHMGSATMEGRIDMGDKVIINIRTFFDGHRPPDRVLPLRS"
     gene            complement(456039..456797)
                     /locus_tag="HPDFL43_20177"
     CDS             complement(456039..456797)
                     /locus_tag="HPDFL43_20177"
                     /note="COG0476 Dinucleotide-utilizing enzymes involved in
                     molybdopterin and thiamine biosynthesis family 2"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin biosynthesis protein MoeB"
                     /protein_id="ZP_02164853.1"
                     /db_xref="GI:163757764"
                     /translation="MDDTHLNADEIARYARHIVLAEVGGAGQQKLKAARVLVIGAGGL
                     GSPVLSYLAAAGVGVLGVTDDDEVSLSNLQRQILHDTANVGIGKTESAARGLKRLNPH
                     VRVITHPVRLTPDNATDIITAYDMVVDGSDNFETRYLLADTCETLAIPLVTAAVGRFD
                     GSVTVLAPYQVNADGKPCPRYRDLFPEAPPPGLVPSCAEAGVIGALTGVIGTLQAMEV
                     IKLITGAGEPLIGRLLLYDGLAASFQTVRYGRKG"
     gene            complement(456832..457980)
                     /locus_tag="HPDFL43_20182"
     CDS             complement(456832..457980)
                     /locus_tag="HPDFL43_20182"
                     /note="COG1195 Recombinational DNA repair ATPase (RecF
                     pathway)"
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA replication and repair protein"
                     /protein_id="ZP_02164854.1"
                     /db_xref="GI:163757765"
                     /translation="MAQKVHIERLKLTGFRNYASQSLELDARHVVLVGDNGAGKTNLM
                     EAVSLLSPGRGMRRAPYSDVIKAGSEPASGFSIFASLEGMAGPVDIGTGVDGLEESGA
                     RKVRINGSPARSADDMLEHLRLLWLTPSMDGLFTGSAGDRRRFLDRLVLSVDPAHGSR
                     ALSYERAMRSRNRLLSEGRADPTWLDGLEAQMSELGVAMAMARSEVVRLLSALIDDSQ
                     AESPFPAASVRLEGFLEDEGLETASDMEVAFIDLMKHGRGRDAAAGRTLSGPHRMDLV
                     VHHRAKAMPAALSSTGEQKALLIGIILGHAQLVRSLTGHAPILLLDEVAAHLDEGRRA
                     ALFDLIETLDCQAFMTGTDAAMFGSLGPRGQMFEVSEGRATPRREAAS"
     gene            complement(458055..459173)
                     /locus_tag="HPDFL43_20187"
     CDS             complement(458055..459173)
                     /locus_tag="HPDFL43_20187"
                     /note="COG0592 DNA polymerase sliding clamp subunit (PCNA
                     homolog)"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="ZP_02164855.1"
                     /db_xref="GI:163757766"
                     /translation="MRVTLERSNLLKSLNHVHRVVERRNTIPILSNVLLKAEGATLDM
                     KATDLDLEITEATPAMIEQAGSTTVPAHLLYDIVRKLSDGSEVMLATNPDGASMTVAS
                     GRSKFTLQCLPESDFPDLTAGAFSHTFRLPATELKMLIDRTQFAISTEETRYYLNGIF
                     VHTIESEGALKLRAVATDGHRLARADVDAPSGSEGMPGIIIPRKTVGEIQKLVDNPDL
                     TVTVEVSDAKIRFTIGSVVMTSKLIDGTFPDYQRVIPTGNDKELTVDCQTFAQAVDRV
                     STISSERGRAVKLAIADGQLTLTVNNPDSGSATEELAVGYDRDPIEIGFNAKYLLDIT
                     NQLSGTDAVFLLADPGSPTLVRDTAGDDALYVLMPMRV"
     gene            complement(459406..460863)
                     /locus_tag="HPDFL43_20192"
     CDS             complement(459406..460863)
                     /locus_tag="HPDFL43_20192"
                     /note="COG0593 ATPase involved in DNA replication
                     initiation"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiation protein"
                     /protein_id="ZP_02164856.1"
                     /db_xref="GI:163757767"
                     /translation="MKKTNDVFERVMARLKAQVGQEIFTSWFGRLKLQSASKSVVRLS
                     VPTAFLKSWINNKYLDQISALYREEAPDVLKIEIVVRSATRSTAVSSAPDAASLPNAS
                     QATPGASASRKEQHVTVKGAGAKFGAFNKGPQAANAVIGSPLDPQCTFDSYVEGSSNR
                     VALAAARTIAEAGTGAVRFNPLFIHSNVGLGKTHLLQAIAAAASSHSRNPRVVYLTAE
                     YFMWRFATAIRDNDALSFKESLRNIDLLVIDDMQFLQGKSIQHEFCHLLNMLLDSARQ
                     VVVAADRAPWELESLDPRVRSRLQGGVAIEIEAPDYEMRLEILRKRLAIAQMEDATLD
                     IDETILAHVAQNITSSGRELEGAFNQLLFRRSFEPNLSIERVDELLGHLVNAGEPKRV
                     RIEDIQRVVSRHYNVTRQELVSDRRTRVIVKPRQIAMYLAKTMTPRSFPEIGRRFGGR
                     DHTTVLHAVRKIEELINGDTKLGHEIELLKRLIIE"
     gene            complement(461747..462013)
                     /gene="rpsT"
                     /locus_tag="HPDFL43_20197"
     CDS             complement(461747..462013)
                     /gene="rpsT"
                     /locus_tag="HPDFL43_20197"
                     /note="COG0268 Ribosomal protein S20"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="ZP_02164857.1"
                     /db_xref="GI:163757768"
                     /translation="MANTTSAKKATRKIARRTEINKARRSRVRGFLRKVEEAISSGDK
                     DAAAAALKAAQPELMRAATKGVVHANTASRKISRLSNRVKAISA"
     gene            complement(462230..463003)
                     /locus_tag="HPDFL43_20202"
     CDS             complement(462230..463003)
                     /locus_tag="HPDFL43_20202"
                     /note="COG1024 Enoyl-CoA hydratase/carnithine racemase"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="ZP_02164858.1"
                     /db_xref="GI:163757769"
                     /translation="MALNTLKTETRGRVAIITLNRPDALNALNSELLGELRETMAKFG
                     DDEKIGAIVLTGSEKAFAAGADIKEMQPLDYVGAYMNDFFEGWSAVANTRKPVIAAVS
                     GYALGGGCELAMMCDIIIASDTAKFGQPEITLGVIPGMGGTQRLTRAIGKAKAMDLCL
                     TGRFMEAEEAERSGLVARVVAADDLMATAIKAAEKIAGFSLPVAMMVKESVNRADEMT
                     LAEGLRFERRLFHSLFATEDQKEGMGAFVEKRKAQFKHR"
     gene            complement(463055..464017)
                     /locus_tag="HPDFL43_20207"
     CDS             complement(463055..464017)
                     /locus_tag="HPDFL43_20207"
                     /note="COG0266 Formamidopyrimidine-DNA glycosylase"
                     /codon_start=1
                     /transl_table=11
                     /product="formamidopyrimidine-DNA glycosylase protein"
                     /protein_id="ZP_02164859.1"
                     /db_xref="GI:163757770"
                     /translation="MRSVNAGERPAITDWHTAEETDLPELPEVETVRRGLQPVMEGAR
                     IIRVEQRRADLRFPFPEDFAKRLEGRQIIALGRRAKYLLADFDDGMVLISHLGMSGSF
                     RIEPDGDSPLTPGVFHHERSKDDKHDHVVFHIDGPAGRARVIYNDPRRFGYMDLMVRA
                     ELAEHPWFRSLGVEPTGNSLEADELARRLAGKAAPLKAALLDQRIIAGLGNIYVCEAL
                     WRARLSPRKPAGRLVTKAGQPRKALERLTGDIREVISEAIAAGGSSLRDHIQTDGTLG
                     YFQHGFSVYDREGKACPRPGCGDTVRRIVQSGRSTFMCARCQKD"
     gene            464086..464238
                     /locus_tag="HPDFL43_20212"
     CDS             464086..464238
                     /locus_tag="HPDFL43_20212"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164860.1"
                     /db_xref="GI:163757771"
                     /translation="MAFLRCLAYKAALYCRSKMVPERMVWLAAIRYGRPAPKRLCAFV
                     RMAARA"
     gene            464240..465037
                     /locus_tag="HPDFL43_20217"
     CDS             464240..465037
                     /locus_tag="HPDFL43_20217"
                     /note="COG2226 Methylase involved in
                     ubiquinone/menaquinone biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone/menaquinone biosynthesis
                     methyltransferase protein"
                     /protein_id="ZP_02164861.1"
                     /db_xref="GI:163757772"
                     /translation="MKQQEPVMSDQRVSTQGGMQTSYGFRTVDDGEKQTLVNDVFHKV
                     AKRYDIMNDVMSGGLHRVWKDALVAKLNPPRRAGFRFLDVAGGTGDIAFRIVAASDNQ
                     AQGTVLDINGSMLGVGAERAVKKGYAGNLEFVEANAEELPFEDNSFDAYTIAFGIRNV
                     PDIDKALREAYRVLRRGGRFLCLEFSEVEMPLLDRIYDAWSFNGIPAMGKAIAGDAEP
                     YQYLVESIRKFPRQDDFAAMITRAGFSRVHYTNYTGGIAALHSGWKL"
     gene            465042..466625
                     /locus_tag="HPDFL43_20222"
     CDS             465042..466625
                     /locus_tag="HPDFL43_20222"
                     /note="COG0661 Predicted unusual protein kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein"
                     /protein_id="ZP_02164862.1"
                     /db_xref="GI:163757773"
                     /translation="MASLGTYLRLMRAGFILVREGVVSSLPAEDLPGPARFAHGVAGL
                     LAKRRAKSAERSDRLARAVERLGPSWVKLGQFLATRPDVVGADIADDLAGLQDRMATF
                     PEVQARAAIESSLGRPISDLYSRFDPPIAAASIAQVHPAEVTDENGSRKVAVKVVRPG
                     VRQRFKRDLEAFYLVSELQERFIPASRRLRPVEITKTLEQTTRIEMDLRLEAAALSEM
                     ADNTKGDPGFRVPFVDWERTGRDCVTMEWIDGIKMSDVAGLKAAGHDLDALADTLIQS
                     FLRHTLRDGFFHADMHQGNLFVDPAGMIVAVDMGIVSRLGKKERRFLAEILYGFITRD
                     YRRVADVHFEAGYVPARHDPASFAQAIRAIGEPIHGQPAETISMARLLTLLFEVTELF
                     DMETRPELVMLQKTMVVVEGVSRTLNPKFNMWKAAEPVVGDWIRDNLGPKRIAVDIKE
                     GAIAALKLAEQLPDLAARTERFATEVGDMAENGLRFDAATSEAIGKAEARHTRSGRVA
                     LWVIAAAAVWLALAIHPIW"
     gene            466619..467059
                     /locus_tag="HPDFL43_20227"
     CDS             466619..467059
                     /locus_tag="HPDFL43_20227"
                     /note="COG0454 Histone acetyltransferase HPA2 and related
                     acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="GCN5-related N-acetyltransferase"
                     /protein_id="ZP_02164863.1"
                     /db_xref="GI:163757774"
                     /translation="MVGLTAYRPISLDDIDVEPLADEAWADGYPFVERMRHDWKSGDN
                     RFDGPGERLIGAFEGETLIGFCGLNRDPYVSENTGRIRHLYVSLDHRHIGIARALVGE
                     ALDGASIQFPRIRLRATPASRSFYELLGFEEVDEAEATHAKRIR"
     gene            complement(467052..467603)
                     /locus_tag="HPDFL43_20232"
     CDS             complement(467052..467603)
                     /locus_tag="HPDFL43_20232"
                     /note="COG1335 Amidases related to nicotinamidase"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="ZP_02164864.1"
                     /db_xref="GI:163757775"
                     /translation="MAHPALMVIDLTNDFLASWETKRRARLIAATNDLVVYFRGKTRP
                     VIWVRQDFKDDLSDAFLEMRDRNVKLNIIGTAGAELDPRLETGEDDVTIVKKRYSPFF
                     GTDLDAVVVEKGIGSMVIAGINTHACVRMAAIDAYQRDMRVILASEAIDCYDEEHARV
                     SLRYMDGKIARVLGNAEIKAEIT"
     gene            467748..468032
                     /locus_tag="HPDFL43_20237"
     CDS             467748..468032
                     /locus_tag="HPDFL43_20237"
                     /note="COG4691 Plasmid stability protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Plasmid stability protein"
                     /protein_id="ZP_02164865.1"
                     /db_xref="GI:163757776"
                     /translation="MATLTIRNLDDSVKQALRERAARHGVSMEEEARVLLRRGIEAKG
                     GAAADAGKSFYDRVRAIVEPIGGIEFDVPPRQLADRPLPFSEWQNESPEE"
     gene            468029..468451
                     /locus_tag="HPDFL43_20242"
     CDS             468029..468451
                     /locus_tag="HPDFL43_20242"
                     /note="COG1487 Predicted nucleic acid-binding protein,
                     contains PIN domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164866.1"
                     /db_xref="GI:163757777"
                     /translation="MILDTNVISEIMRPVPDHNVVAWFDETVSEQRHITAITEAELLL
                     GISLMPIGKRRNEYAAAIARILSLETGNPILPFESADATFFAEAMSTRRRAGRPLKEL
                     DAQIAAIALRRGLPIATRNVRDFEGCGVTLINPWDPAP"
     gene            468448..469650
                     /locus_tag="HPDFL43_20247"
     CDS             468448..469650
                     /locus_tag="HPDFL43_20247"
                     /note="COG0452 Phosphopantothenoylcysteine
                     synthetase/decarboxylase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative coenyzme A biosynthesis bifunctional
                     protein"
                     /protein_id="ZP_02164867.1"
                     /db_xref="GI:163757778"
                     /translation="MTLSGKRILLIISGGIAAYKSLDLIRRLRERGAEVRPVMTAGAQ
                     EFVTPLAVGALAADHVYTELFSREDEQDVGHIRLARDCDLICVAPATADLMAKMANGL
                     AGDLATTVLLATNKPVLISPAMNPAMWAHPATRRNTETLKRDGIGFIGPMSGEMAESN
                     EAGEGRMAEPLQIVAAIEALLDDAPKPLAGKKAIVTSGPTHEPIDPVRYIANRSSGKQ
                     GHAIAGALARLGAEVTLVSGPVTIPDPAGVNLIHVESAANMLDAVTSSLPADIAVFVA
                     AVADWRVATASGNKIKKKEGEGPAPLELTENPDILKTIGHHENRPQLVVGFAAETADV
                     VSNAQAKLARKGADFIVANDVSPETGIMGGDRNRVRIVSKDGVEDWPDLSKDETAARL
                     AERIAGAF"
     gene            469852..470055
                     /locus_tag="HPDFL43_20252"
     CDS             469852..470055
                     /locus_tag="HPDFL43_20252"
                     /note="COG0452 Phosphopantothenoylcysteine
                     synthetase/decarboxylase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative coenyzme A biosynthesis bifunctional
                     protein"
                     /protein_id="ZP_02164868.1"
                     /db_xref="GI:163757779"
                     /translation="MIANARVKLARKGADFIVANDVSPGTGIMGGDRNRVRIVSKDGV
                     EDWPDLSKDEVAERLAERIAEAI"
     gene            complement(470309..471091)
                     /locus_tag="HPDFL43_20257"
     CDS             complement(470309..471091)
                     /locus_tag="HPDFL43_20257"
                     /note="COG0121 Predicted glutamine amidotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164869.1"
                     /db_xref="GI:163757780"
                     /translation="MPIPLEQIVSAPGHSLIEQSHHATEAKTATNGDGFGIAWYGEHP
                     EPGRYRDVLPAWSDCNLKSLARQIRSPLFLAHVRASTGGATSRDNCHPFVNGKWSFMH
                     NGQIAGFEKIRRPMEAALCDRLYQARQGTTDSELLFLLALEFGLETDPAAAFAQAIRF
                     ALSEAARAGVRELVRFTAAFSDGETLHAIRYSNDAQAPTLYSAPTCNNQGHCLVSEPF
                     KDTDTKWHEIPAGSFVTLTAGGISSARFDPAQTDAVKVAEVA"
     gene            complement(471130..471342)
                     /locus_tag="HPDFL43_20262"
     CDS             complement(471130..471342)
                     /locus_tag="HPDFL43_20262"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164870.1"
                     /db_xref="GI:163757781"
                     /translation="MPRQIARLFTDHPQSVDETYFEHLVFAGKFSAKLFAAGVCALVH
                     AILPFTFEKTASRIINELHHRMHNRS"
     gene            471451..471930
                     /locus_tag="HPDFL43_20267"
     CDS             471451..471930
                     /locus_tag="HPDFL43_20267"
                     /note="COG1522 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="ZP_02164871.1"
                     /db_xref="GI:163757782"
                     /translation="MHQIDDMDVRILGQLQRDGTLSVDALSERVNLSRNACWRRVKQL
                     EERGLIRDRVAILDAEAAGCGLSVFIFLRAASHDADWLKSFREAVGTFPEIVGVYRTS
                     GDLDYVLRARVSDVKAYDRLYQRLIAKVKLADVSASFVMEEIKETTAIPLSALSRKA"
     gene            472140..472487
                     /locus_tag="HPDFL43_20272"
     CDS             472140..472487
                     /locus_tag="HPDFL43_20272"
                     /note="COG0640 Predicted transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, ArsR family protein"
                     /protein_id="ZP_02164872.1"
                     /db_xref="GI:163757783"
                     /translation="MDEDAMSRILKAAGDTTRRQILTLLVQEGALRVTALSAHFDMSL
                     NSVSKHIKVLEEAGLVTRRTVGREHFIAAELEPLQLTESWFGQLKSIWELRLVALEEA
                     LVSKDDDNDGNNQ"
     gene            472468..472905
                     /locus_tag="HPDFL43_20277"
     CDS             472468..472905
                     /locus_tag="HPDFL43_20277"
                     /note="COG3832 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164873.1"
                     /db_xref="GI:163757784"
                     /translation="MTETINELELTVSRRIPAPRDKVFDAWLSPPILAKIMRPGGKHM
                     TSKVTNDPVKGGRFSIIMNDAGKEMPHAGTYLEIDPHSRLAFTWESAHSPDDSVVTID
                     FTESEPGITDVTLHQVRFLSEQARDSHRGGWTAILECIEEAVA"
     gene            473067..474227
                     /locus_tag="HPDFL43_20282"
     CDS             473067..474227
                     /locus_tag="HPDFL43_20282"
                     /note="COG0845 Membrane-fusion protein"
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocation pathway signal
                     sequence domain protein"
                     /protein_id="ZP_02164874.1"
                     /db_xref="GI:163757785"
                     /translation="MEMIMQRRNFMKVLGGGVILAAGAGAGFAMTRTPSRALAPWQRA
                     GGSTYADPRMRALSYAILAPNPHNRQPWQVELQGEDTVVLTVDLDRLLPHTDPFSRQI
                     TIGLGCFLELMVMAAAQTGHRVEIEPFPQGADSERLTTAPVAIARFVQDPGIRPDPLF
                     AHVMARRSNKEPFDTARAVPDAALAAIVASARHGGRLGGTNDAAEVASWRTLTETALQ
                     IEIDTPHTYKESVDLFRIGKAEVNANPDGIDFSGPMFETLALFGQFNRELALDRTSAG
                     FKQGVDAVLENTRTAMAHVWMVTDGNSRADQIAAGADWLRANLAATSQGIGFQPLSQA
                     LQEFPEMAELYRDVHARLAPNGGTVQMLVRLGYGPGVPVSPRWPLEAKLREA"
     gene            474234..474704
                     /locus_tag="HPDFL43_20287"
     CDS             474234..474704
                     /locus_tag="HPDFL43_20287"
                     /note="COG1846 Transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, MarR family protein"
                     /protein_id="ZP_02164875.1"
                     /db_xref="GI:163757786"
                     /translation="MGAGNSQDGKPGPGEIFAYFTEIGIISQLSSALLARVLPDGVHP
                     SHFAIVQHLIRRGDGKPPVRIAAAMQITKATMTHSLAVLEKRGFVETRPSPEDARSKL
                     VYLTDAGRAFHAEAIEGVIRAFGRIIGDEHAEIMRQAMPGLVAIRKLLDDNRDL"
     gene            complement(474898..475611)
                     /locus_tag="HPDFL43_20292"
     CDS             complement(474898..475611)
                     /locus_tag="HPDFL43_20292"
                     /note="COG1028 Dehydrogenases with different specificities
                     (related to short-chain alcohol dehydrogenases)"
                     /codon_start=1
                     /transl_table=11
                     /product="short chain dehydrogenase"
                     /protein_id="ZP_02164876.1"
                     /db_xref="GI:163757787"
                     /translation="MLFSDHVALVTGANRGLGRAVAAALIAAGAKKVYAASRSGDPIG
                     LEGTVPIRIDVTDPETVRAAALACPDVTLLINNAGVAGFSGPISAPSMDTARHEMEVN
                     YFGTLTTTRSFAPVISTNGGGTIVNVASILAYGPIPQVGTYSATKAAVLSMTQSLRGE
                     LAPKNIQVLALCPAFVDTDMIAKVDQPKMTPEDVANALVEGVIAGTEEMFPGPSAGMA
                     AAFRADPKGYERKIINFLA"
     gene            475734..476282
                     /locus_tag="HPDFL43_20297"
     CDS             475734..476282
                     /locus_tag="HPDFL43_20297"
                     /note="COG1309 Transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, TetR family protein"
                     /protein_id="ZP_02164877.1"
                     /db_xref="GI:163757788"
                     /translation="MRVSRQTAEKNRETVVRTASEQFRTLGYDGIGIANLMKAAGLTQ
                     GGFYKQFKSKDALEIEATRLALQENHQRWAQIMDGASGPIQVLKDWYLSPQHVSAVGK
                     GCTYATLGAEANRQGREMQQVFGAAIEQQVSALAGKLGDSVEAREDAIRTMAQMVGTL
                     ILARAVSDADLQDEILKAGKGT"
     gene            complement(476341..476796)
                     /locus_tag="HPDFL43_20302"
     CDS             complement(476341..476796)
                     /locus_tag="HPDFL43_20302"
                     /note="COG3238 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164878.1"
                     /db_xref="GI:163757789"
                     /translation="MGFSLLLVLAVMLGGVLVAAQGPLYARMASGLSANPLVAVFFAF
                     ASATLVLGACLLIGQVRLPEAKQVLALPWWVWLGGLFGAYQVMISAQAVPVLGVTLFL
                     MLVMLGNMAGAVIFDHFGWFGLPRRPVSWPAVAGVGLMLAGVFVTVSRG"
     gene            complement(476805..477332)
                     /locus_tag="HPDFL43_20307"
     CDS             complement(476805..477332)
                     /locus_tag="HPDFL43_20307"
                     /note="COG0454 Histone acetyltransferase HPA2 and related
                     acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="ZP_02164879.1"
                     /db_xref="GI:163757790"
                     /translation="MAEIHVQSLAGEALEAHADALAEIIAQTVNDGAAIGFMQPFDEA
                     DGRAFFEGQVFPEVRAGRRRLIMAWLDGVPAGSVQLIVTLPANQPHRSEVAKMMVAPA
                     ARRRGVGRALMAAVDTAARDLGKRLITLDTRTGDVSEPLYRTAGFVEAGVIPGYALDP
                     DGKQLHATTYMYKTL"
     gene            complement(477341..477889)
                     /locus_tag="HPDFL43_20312"
     CDS             complement(477341..477889)
                     /locus_tag="HPDFL43_20312"
                     /note="COG1396 Predicted transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="Transcriptional regulator, XRE family protein"
                     /protein_id="ZP_02164880.1"
                     /db_xref="GI:163757791"
                     /translation="MDTLNDRLADRLKQLRATRGWSLQQLADISGVSRSALSRIETGE
                     VSPTAETLGAMSSAFQMTISQLLAPVEAPFQPLVRAEEQSTWRDDENGFSRRVVSPPA
                     GGLSAEVIRCTLEPYQIISYAGPSKPGHEHHLVMLEGALTVTLGEEMHQLAAGDCLRY
                     QLYGPSRFQTGVDAACYLIMLV"
     gene            complement(477994..479028)
                     /locus_tag="HPDFL43_20317"
     CDS             complement(477994..479028)
                     /locus_tag="HPDFL43_20317"
                     /note="COG0701 Predicted permeases"
                     /codon_start=1
                     /transl_table=11
                     /product="permease, putative"
                     /protein_id="ZP_02164881.1"
                     /db_xref="GI:163757792"
                     /translation="MSLATETGRPGAQELKAWLTTPWAFMLLILAGVAVLDGGRFTGI
                     VSFAVAALGSTLPYIIFAVALIAGLKAAGAEAVIAEAFKGRETKMIVMAALFGGLAPF
                     CSCEVIPFVAGLLALGAPLSAVMAFWLSSPLIDPPTLLITAAALGWPFAAGKAVAAVA
                     LGLFGGFAIKAAIAGGRFSAPLKIYNKKGCGCGPDPFSGKPVWRFWGEASRREAFRHE
                     AIINGMFLIKWLALAYVLEALLVTYVPAEMVAGLVGGEGVVPIGIAALVGMPAYLNSY
                     VAPPLLAGLMEQGMSPGAAMAFMISGAVSSVPAMAAVWSLVRKPVFATYIGLGVSGAV
                     ASGIIFQMVL"
     gene            complement(479025..479324)
                     /locus_tag="HPDFL43_20322"
     CDS             complement(479025..479324)
                     /locus_tag="HPDFL43_20322"
                     /note="COG0640 Predicted transcriptional regulators"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, ArsR family protein"
                     /protein_id="ZP_02164882.1"
                     /db_xref="GI:163757793"
                     /translation="MNAIEAAQGFSAMGSESRLEVLQTLVRAGEAGLRVGDIQERTGI
                     TASTLAHHLKFLSAANLIVQRKQGRVIMSTANFAHLNLLASFILEKCCSEQGVQP"
     gene            479545..479952
                     /locus_tag="HPDFL43_20327"
     CDS             479545..479952
                     /locus_tag="HPDFL43_20327"
                     /note="COG0589 Universal stress protein UspA and related
                     nucleotide-binding proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress family protein, putative"
                     /protein_id="ZP_02164883.1"
                     /db_xref="GI:163757794"
                     /translation="MYKNILVAVALDQAHDSAAAFDIARALASRGAAITALHVLEEIP
                     AYVAHYIPPENTSNRRSEAEAELKADLGGVTDVKPVVLSGHPGSTIVEYATAHDIDCI
                     IIASHRPGLQDYFLGSTAGRVVRHAKCAVHVIR"
     gene            complement(480013..480894)
                     /locus_tag="HPDFL43_20332"
     CDS             complement(480013..480894)
                     /locus_tag="HPDFL43_20332"
                     /note="COG0583 Transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, LysR family protein"
                     /protein_id="ZP_02164884.1"
                     /db_xref="GI:163757795"
                     /translation="MIDWSDLRYVLETVRHSGLSGAARALGVNHATVARRIQAAEQAS
                     GAVLFDRLPGGYAPTAAGLEAARAAEAMEAANAALSLSITARDERLSGPLSVTAPQLL
                     IERVLGGILAEFCAAHPEIELQLFASNEALNLSQREADVAIRVSDAPLDTLVGSRVAD
                     QRAAVYVSRAYGERLGTTPGQRLDWIRFSHWPGVPAELNTAWPERRVALVLDDMAAAI
                     GAVRAGIGATRMPCFLGETDPQLVRLPGVPLFAYPSIWVLTHRDLQRVRRIETFVEFA
                     SARLRRLRPVFVGDPKG"
     gene            480921..481298
                     /locus_tag="HPDFL43_20337"
     CDS             480921..481298
                     /locus_tag="HPDFL43_20337"
                     /note="COG5470 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164885.1"
                     /db_xref="GI:163757796"
                     /translation="MQSSSVFEQAGGSYIRASQHNQGTDIMTTPAGKPAHAIVTMTIT
                     SPDSLAQYREKAADALSRHGGSVLQASATLDLLEGGPDLPTMAAVLSFPRREDALAWI
                     EDPELAPVHALRRGSGHSTIVLL"
     gene            complement(481388..481609)
                     /locus_tag="HPDFL43_20342"
     CDS             complement(481388..481609)
                     /locus_tag="HPDFL43_20342"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164886.1"
                     /db_xref="GI:163757797"
                     /translation="MHRAFGVADHAACGGAEETVLQAGAVGGNDDAVDLVGGGVFDDC
                     GARMSCLNGMEWWPRCGQASTHDRLTGPD"
     gene            complement(481813..482727)
                     /locus_tag="HPDFL43_20347"
     CDS             complement(481813..482727)
                     /locus_tag="HPDFL43_20347"
                     /note="COG1106 Predicted ATPases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative atp binding protein"
                     /protein_id="ZP_02164887.1"
                     /db_xref="GI:163757798"
                     /translation="MLSLHNCPNNSLVLIDELEMALHPMAQIKFVEYLKEISEQKNLT
                     SIVSTHSASLIKYFGRKHLSFLNKNGQNTRVLKNCFPTYALGQLGFGEERAPDYLVYV
                     EDKAARRISEILWQNLVAERLGARAAYAPTVHFVEIGGIYNVLNMIANGGGLVPEQTK
                     VLALLDLDAKTETLQKAIDSKNLSAQQLFANCDKQLKYLPWTPEVGIIHYLSTHHADA
                     QDALRLQTSTNYLRLPEPTADELTADTGGQQRKVAKTGLSRICRETAEALPNLGGDDI
                     KDLIYKAFCDWSFVNEKPRVQAIFGPFF"
     gene            complement(484462..486051)
                     /locus_tag="HPDFL43_20352"
     CDS             complement(484462..486051)
                     /locus_tag="HPDFL43_20352"
                     /note="COG4108 Peptide chain release factor RF-3"
                     /codon_start=1
                     /transl_table=11
                     /product="probable peptide chain release factor rf-3
                     protein"
                     /protein_id="ZP_02164888.1"
                     /db_xref="GI:163757799"
                     /translation="MPEPLAEEVGRRRTFAIISHPDAGKTTLTEKLLLFGGAIQLAGE
                     VKAKKDRIQTRSDWMKIERERGISVVTSVMTFEYDNHVFNLLDTPGHEDFADDTYRTL
                     TAVDAAVMVIDAAKGIEPRTLKLFEVCRLRDIPIITFVNKMDREARNPFEILDEVEQK
                     LALDTAPMTWPIGQGKSFSGTYHLAKSAMRGPDRETALTPVNGPESDKVAGLLPENER
                     ETFIEETSLAVEACRPFDLEAFREGHLTPVYFGSALKAFGVRDLINALGELAPPPRAQ
                     VADIRTVEATDAKMTAFVFKIQANMDPNHRDRIAFVRVCSGKLQRGMKARLSRTGKPM
                     GLSAPQFFFASQRQIADTAYAGDVVGIPNHGTLRIGDTLTEGEALVFQGVPNFAPEIL
                     RRVRLEDAMKAKKLKEALQQMAEEGVVQLFSPEDGSPAIVGVVGALQLDVLKERLQAE
                     YGLPVSFEMARFSVCRWISAPEKPELERFIDRHRGDIARDLDGDPVFLASDQFSLNYE
                     AERYPDIKMVAIKEYHVAKAA"
     gene            486145..486651
                     /locus_tag="HPDFL43_20357"
     CDS             486145..486651
                     /locus_tag="HPDFL43_20357"
                     /note="COG0756 dUTPase"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyuridine 5`triphosphate nucleotidohydrolase
                     protein"
                     /protein_id="ZP_02164889.1"
                     /db_xref="GI:163757800"
                     /translation="MTHHDRPANIAVDPTAARVPELLILRLPHGEGLELPAYETPGAA
                     GMDLRAAVSEGEPFELAPGARAAIPTGLVMEIPHGFEGQVRPRSGLALKSGITCLNTP
                     GTIDSDYRGEVKVILANLGAEPFLVTRGMRIAQMVIAPVVQARILLAEAVDETARGAG
                     GFGSTGTA"
     gene            486648..487652
                     /locus_tag="HPDFL43_20362"
     CDS             486648..487652
                     /locus_tag="HPDFL43_20362"
                     /note="COG3938 Proline racemase"
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="ZP_02164890.1"
                     /db_xref="GI:163757801"
                     /translation="MSAPLKVIDMHTGGEPLRIVTAGYPELPKGTILEKRAHVRDHLD
                     DLRKILMFEPRGHFDMYGALLVEPDLPGADLAVLFMHNEGYSTMCGHAIIALGRYAVD
                     QGLVEPQGDRALVNIECPCGMVRAEVAVRDGKAAEVSFESVPSFLFAGDQKLSLEKHG
                     EITFDIAYGGAFYALAGCSQFGLEFGRDPVAAFVEAADQLTRAAHAAIPLSHPDAQDL
                     AFLYGSILTDGQDAFSDQSTRNICVFADRQVDRSPTGSGVTARLAAMHARGQIALGQQ
                     RTFESIIGSRFSGSVASVTACGPHPAITAKVSGRAYYSGKTEFIVEDDDPLAAGFLVR"
     gene            complement(487703..488719)
                     /locus_tag="HPDFL43_20367"
     CDS             complement(487703..488719)
                     /locus_tag="HPDFL43_20367"
                     /note="COG0111 Phosphoglycerate dehydrogenase and related
                     dehydrogenases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative dehydrogenase"
                     /protein_id="ZP_02164891.1"
                     /db_xref="GI:163757802"
                     /translation="MRIILDPEPRTAEDIFSEADYQELTRRHDVIVYSGEDRDVFYTR
                     HLPDCDILLGQADMGPDRLAMASKLKAIINVETNFLPNVDYETCFQRGIHVLAPSGVF
                     ALPVAEMGLGMAISLARGIHSEHKRFTEGNERYGLSGNQDAELLSGSDFGFVGFGDLG
                     RALFALLPGFRPNSVKVFDPWLPDAHLERMGVAPASLDAVLEQSRFVFVVASITTENQ
                     HLLNAGNLSRMQPGASLILLSRAAVVDFDAVSKLVGSGAIRFATDVFPEEPVTADDPV
                     RALPNTLFSPHRAGALESALKDIGNRVIEDIGQIANGLPPISCKRAERETVTRMRSKP
                     IDKT"
     gene            489019..489987
                     /locus_tag="HPDFL43_20372"
     CDS             489019..489987
                     /locus_tag="HPDFL43_20372"
                     /note="COG0031 Cysteine synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase"
                     /protein_id="ZP_02164892.1"
                     /db_xref="GI:163757803"
                     /translation="MSDSKEIGRGRIYNSILDTVGDTPIVRLDKLAKEKGVKAHLLGK
                     LEFFNPIASVKDRIGVAMIESLEAQGKIEPGKTTLVEPTSGNTGIALAFAAAAKGYRL
                     ILTMPETMSVERRKMLALLGAELVLTEGPKGMKGAIARAEELIGEIEGSVMPQQFENP
                     ANPEIHRKTTALEIWNDTDGGVDILISGIGTGGTITGTGQVLKAKKPGVKVVAVEPAD
                     SPVLSGGNPGPHKIQGIGAGFAPAILDTGIYDEVVQVSNDEAFAMAREVARLEGLPVG
                     ISSGAALTAAVKVGSREENAGKQIVVIIPSFAERYLSTALFDGLGD"
     gene            complement(490096..491628)
                     /locus_tag="HPDFL43_20377"
     CDS             complement(490096..491628)
                     /locus_tag="HPDFL43_20377"
                     /note="COG0606 Predicted ATPase with chaperone activity"
                     /codon_start=1
                     /transl_table=11
                     /product="probable Mg-chelatase protein"
                     /protein_id="ZP_02164893.1"
                     /db_xref="GI:163757804"
                     /translation="MVARVSTVAFEGIEAVPVDVQVMVAPGKVGMHIVGLPDKAVAES
                     RERVQAALHASGLALPAKKVTINLAPADLPKEGSHFDLPIALGLMAALGAIPGDALNG
                     YVVLGELSLDGTIASVAGALPAAIGANALGKGLICPAASGPEAAWAGEDIEILAPRSL
                     IAMANHFRGTQVLARPKPAMRAEPANMPDLCDIRGQETAKRALEVAAAGGHNLIMVGP
                     PGSGKSMLAARLPSILPPLSPAELLEVSMIHSIAGRLAGGRLSERRPFRAPHHSASMA
                     AMVGGGFKARPGEVSLAHHGVLFLDEFPEFTPQVLDSLRQPLENGECVIARANHRVSY
                     PANIQLIAAMNPCRCGMAGEPGQSCARGPRCQSDYQGRISGPLMDRIDIRIDVPAVTA
                     QDLIRPQDAEKSVDVAARVAMARVTQQERYRALGRSDIRTNSQCTTALVEEVARPDSG
                     GQALLSDAAEKMRFSARAYHRILKVARTLADLDGAETVSRIHLAESISYRIAAERITK
                     AA"
     gene            complement(491930..492232)
                     /locus_tag="HPDFL43_20382"
     CDS             complement(491930..492232)
                     /locus_tag="HPDFL43_20382"
                     /note="COG2350 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164894.1"
                     /db_xref="GI:163757805"
                     /translation="MAFLDDGDHLFVIDLTYVTALENVDPLIEPHMAFIERNYGTGRF
                     LASGAKVPRTGGVIIARGQSLQDIETLIRDDPFHSAGIADYTITEFRPGNIAAVLT"
     gene            complement(492400..493347)
                     /locus_tag="HPDFL43_20387"
     CDS             complement(492400..493347)
                     /locus_tag="HPDFL43_20387"
                     /note="COG0189 Glutathione synthase/Ribosomal protein S6
                     modification enzyme (glutaminyl transferase)"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthetase protein"
                     /protein_id="ZP_02164895.1"
                     /db_xref="GI:163757806"
                     /translation="MSKIKNVAVQMDHVRSISIAGDSTFAMSMEAQARGYKLFHYTPD
                     QLSMRDGVVQAVAEPMILRDVEGDHFELGPQETINLADMDVVLLRQDPPFDMAYITST
                     HLLERVHPKTLVVNDPAWVRNSPEKIFVTEFPDLMPKTLISRDPETIKAFRAEVGDMI
                     LKPLYGNGGAGVFHIKPDDRNMTSLLEMFAQMYREPFIAQEYLPHVRAGDKRILLIDG
                     EPVGAINRVPAEHDSRSNMHVGGRAEHSELTDREKEICARIGPALRERGFILVGIDII
                     GDLMTEINVTSPTGLREVKRFGGADIASLFWDAVEAKKH"
     gene            complement(493536..494186)
                     /locus_tag="HPDFL43_20392"
     CDS             complement(493536..494186)
                     /locus_tag="HPDFL43_20392"
                     /note="COG2370 Hydrogenase/urease accessory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164896.1"
                     /db_xref="GI:163757807"
                     /translation="MRPASIRFDQLAARLVPMALAGGLFCFVPLDAKAHEFALGGDAY
                     EDFLAGGMAVLIDLPVMIALISTGILVSMWKREGLPLVWPAFLLAIPAGFVTAALVPV
                     DPVPLLFATAIALGLLAVMAIRPAVRTMAAIVFLAGLLTGWGILAGHAWGEVPPGAYA
                     GIFGLFNLVLATSAAIVSTGLKRLPYGWVEISFRALASWMVAIAMMGWAFLAGQTG"
     gene            complement(494199..494744)
                     /locus_tag="HPDFL43_20397"
     CDS             complement(494199..494744)
                     /locus_tag="HPDFL43_20397"
                     /note="COG2370 Hydrogenase/urease accessory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164897.1"
                     /db_xref="GI:163757808"
                     /translation="MAASPALAHTGEGMTGGFLSGLLHPIFGWDHVVAMVAVGLWGAV
                     LGSPAIWILPITFPLVMALGAALGIAGIPVPFIEAGIALSGVVLGLLVLFLVRAPVVV
                     AGVLVAFFAVFHGYAHGTELPTAANPFAYAIGFVIATGLLHGVGIGLGALNGLAWGKP
                     AIRVGGAIIALVGTAFLTGIA"
     gene            complement(495021..495839)
                     /locus_tag="HPDFL43_20402"
     CDS             complement(495021..495839)
                     /locus_tag="HPDFL43_20402"
                     /note="COG0583 Transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, LysR family protein"
                     /protein_id="ZP_02164898.1"
                     /db_xref="GI:163757809"
                     /translation="MNEKTASWDDLYLFLAVAREGGLSPAARVTGRSAATLGRRMLAL
                     ERATGRELFVRHERGYELTTQARELLEELTGIEARIARLTSHPGETERPLVKVSAGTW
                     TTLALLAHLDEITGTPADIRLRFVSAETTLDIARREVVIGFRNARPTGDSLAGRKLSR
                     VEFAPYASAGAPERWIKVLADTPSARWLDRMVGNDAVCEVNAPRNSLDLALAGQGIAL
                     LPTFIGERQPVLRQTGSTIPELAHDQWIVTHQDDRHLPEVRRTIDRLCRVFGGR"
     gene            complement(496232..496600)
                     /locus_tag="HPDFL43_20407"
     CDS             complement(496232..496600)
                     /locus_tag="HPDFL43_20407"
                     /note="COG0792 Predicted endonuclease distantly related to
                     archaeal Holliday junction resolvase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164899.1"
                     /db_xref="GI:163757810"
                     /translation="MSAGGKLTRKRRSERKGRRAEWLAAFALMLKGYRISALRYKTPL
                     GEIDLVARKGDLIAFIEVKARRDLAAGVDSVSYASQRRIRAAGDVYISRQPDAERLSW
                     RFDIIVVSPWRWPVHLEDAF"
     gene            complement(496597..497547)
                     /locus_tag="HPDFL43_20412"
     CDS             complement(496597..497547)
                     /locus_tag="HPDFL43_20412"
                     /note="COG0313 Predicted methyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="probable methyltransferase protein"
                     /protein_id="ZP_02164900.1"
                     /db_xref="GI:163757811"
                     /translation="MARRTPKDTGSDNTAATGQTSRGYRIGAHEIGARPLAAGLYLVA
                     TPIGNLGDITLRALETLAGADIIACEDTRVSRVLLDRFGIATRPYAYHEHNAERVGPK
                     LMAALEAGKSVALISDAGTPLVSDPGYRISQTAIEAGLPVIPIPGASAPMAALVASGL
                     PSDTFLFAGFLPSKDKARRDRLASFAATEATLMFFESPNRLAASLKSAADMLGAERPA
                     AVCRELTKAYEEIRRGTLGELAARYENENVRGEIVLVIGPGFTPAPSEDDVDALLARL
                     ASDLPAGKAATEAARLTGLNRKELYARLLAMKAAPPKGEA"
     gene            complement(497693..498529)
                     /locus_tag="HPDFL43_20417"
     CDS             complement(497693..498529)
                     /locus_tag="HPDFL43_20417"
                     /note="COG0730 Predicted permeases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164901.1"
                     /db_xref="GI:163757812"
                     /translation="MSPAIWPLRCRRRRSTLTGTATGDHMILTLSQLTGLSAAQLAFV
                     VAAVFMAGLARGFSGFGLSAVVMASLAVIIPPVELIPVCFLLECAASLAMFRGGMALA
                     DMRVVWALVISSSIGVPIGLLATTSIDVAWSQKIALSIILCLTLMQFFNLRPGFLATR
                     GGLYMSGVTAGIATGLASVGGMVIALYVLASGAPPKQMRASLVMFLAITMVTSLVFLI
                     AYDLMTMQALWRGALMVPLVLLGVFSGARLFRPAYEHLYKAACLGLLALLSAAGLISQ
                     LF"
     gene            complement(498608..500776)
                     /locus_tag="HPDFL43_20422"
     CDS             complement(498608..500776)
                     /locus_tag="HPDFL43_20422"
                     /note="COG2199 FOG: GGDEF domain"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase/phosphodiesterase"
                     /protein_id="ZP_02164902.1"
                     /db_xref="GI:163757813"
                     /translation="MGPLPGSAMGRVTTTLVVAVALSILITATLGYVKVSELTATNSA
                     IRIDRAARTAVATITHDLKSEFESVLDEEGRPLAVRLKYDNAETALSFRDEHSVLLNE
                     IARVNQGAANLFKFNRQTDGFDRFATTFRKPDGSMPPPMSISAGHPAYASLAAGKPFL
                     GEVPVMGRLRLAYLTPIVSSAGTVEGALAVDVGWVDDLIVARTELGSEMMVTAGLLLL
                     IVAFFGAAFMAWQLEPIRILAGYADDLADNRQSTKVPFKDSKDEFGALALALERLANL
                     QHRLAGIAYTDQITGLGNRSRYLADLEAAVAETRSGSAQWCLLHLDLDNFFQINDAYG
                     PVNGDKLLIMVGEEVKRLAGARAKLARPASDEFTILVDDRPTADEVAWLAESVLEALR
                     QPFHLPCGEVHTCGSIGIVLPGDDAADADTMHLNAELARRKAKANGGNQAVFFTPELN
                     NALQDQLELEGMLRSAIAERELEVHFQPQINPANHQLVGLEALARWTHPEKGPIPPGR
                     FIPIAESSGQIMDLGSLVFDLACAQAAKWRRDGFDFKHISVNVSPMQLGQANFIEMLK
                     STLERHNLPGETICIEITESVFVDQNEERIARIFAGVHTLGLRLALDDFGSGYSSLGY
                     LNQLPLEQLKVDRCFVSDIDTDTRKQKVLRGILELARGLGFEIVVEGTETLEEVRMVE
                     AMGCDAVQGYYFARPSPASLVPDMVAKIALSRREPPALRA"
     gene            complement(501100..502344)
                     /locus_tag="HPDFL43_20427"
     CDS             complement(501100..502344)
                     /locus_tag="HPDFL43_20427"
                     /note="COG0635 Coproporphyrinogen III oxidase and related
                     Fe-S oxidoreductases"
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="ZP_02164903.1"
                     /db_xref="GI:163757814"
                     /translation="MSGLVDQAEAPDPLAAMAKARSNAFKDGLAPDTGKPGFAVYLHW
                     PFCAAKCPYCDFNSHVRHEGIDQQAYIDAFRAEIAAMRKLSGPQVVTSIFFGGGTPSL
                     MHPETVAAILDAVHETWVVPEGIEITLEANPSSVEAGRFRGYRAAGVNRVSMGVQALN
                     DRDLKRLGRLHDRAEALRAIGLARDIFPRMSFDLIYARPDQTPHAWEAELKEAISLAA
                     DHLSLYQLTIEEGTPFYGLHKAGKLIVPDGDLSAELYELTQSVCEAHGLPAYEVSNHA
                     RPGAESRHNLTYWRYGDYAGIGPGAHGRLTTSAGKIATATERTPETWLTSVADRGHGM
                     SESEVLGTSEQADELLLMGLRLREGVDLGRWQALSGHRLDAERVEFLIDHGMIETMGK
                     DRIRCTPQGMLVLDAVVADLAT"
     gene            complement(502341..502994)
                     /locus_tag="HPDFL43_20432"
     CDS             complement(502341..502994)
                     /locus_tag="HPDFL43_20432"
                     /note="COG0127 Xanthosine triphosphate pyrophosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative deoxyribonucleotide triphosphate
                     pyrophosphatase"
                     /protein_id="ZP_02164904.1"
                     /db_xref="GI:163757815"
                     /translation="MAHAPLTEILVASHNAGKIAEIRDLFGPLGVAVTSAAELNLPEP
                     EETGDTFEANAATKALAAATASGKIALSDDSGLIVDALDGAPGVYTADWATLPDGSRD
                     FAVAMQKVEDALQARGALTEAKRTGRFVSMLCLATPDGDVSFYRGEADGVMVWPPRGT
                     SGFGYDPVFRPDGHTRTFGEMTAEEKHGWKPGQATATSHRARAFKLFAEQRLGVPVT"
     gene            complement(503016..503732)
                     /gene="rph"
                     /locus_tag="HPDFL43_20437"
     CDS             complement(503016..503732)
                     /gene="rph"
                     /locus_tag="HPDFL43_20437"
                     /EC_number="2.7.7.56"
                     /note="COG0689 RNase PH"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="ZP_02164905.1"
                     /db_xref="GI:163757816"
                     /translation="MRPSGRKTDQMRAVSFERGVSKHAEGSCLVKFGDTHVLCTASLE
                     ERVPPWLRNGGKGWVTAEYGMLPRSTGDRMRREATSGKQGGRTLEIQRLIGRSLRAVV
                     DLPALGERQITVDCDVIQADGGTRTAAITGAWIALHDCLKWMEERSMVKVERVLKDHV
                     AAVSCGIFAGQAVTDLDYLEDSSAETDANFVMTGTGGIVEIQGTAEGEPFTEEQLGQL
                     MGLAKAAINDLVALQKSAVA"
     gene            503843..503944
                     /locus_tag="HPDFL43_20442"
     CDS             503843..503944
                     /locus_tag="HPDFL43_20442"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164906.1"
                     /db_xref="GI:163757817"
                     /translation="MLLNWSYPFLVVRQIPIFALNRVRHQRGPEDTI"
     gene            503941..505026
                     /locus_tag="HPDFL43_20447"
     CDS             503941..505026
                     /locus_tag="HPDFL43_20447"
                     /note="COG1420 Transcriptional regulator of heat shock
                     gene"
                     /codon_start=1
                     /transl_table=11
                     /product="putative heat-inducible transcriptional
                     regulator"
                     /protein_id="ZP_02164907.1"
                     /db_xref="GI:163757818"
                     /translation="MSMDRTALPAELAGELDDRSREIFRALVESYMESGDPLGSRSLS
                     RMLPMSLSPASIRNVMSDLEDLGLIYAPHVSAGRLPTQKGLRFFVDAFMQVGDLQPEM
                     RESIERQVRPNDQNSPVETLLTEASQMLSGMTRGAGLVIASKQDSTIRHIEFIRLDQS
                     RALVVLVGGNDQVENRIMELPDGVTAGQLVEAANFLNAHLAGRTLSEVRAELQRITDE
                     VRNELDALSRDLVERGLAAWAGSQGGSGAARLIVRGRANLLEGVSEGEELDRLRMLFD
                     ELERNENLTELMTAAEEGSGVRIFIGSENKLFSLSGSSVIVAPWRDSEERVVGAVGII
                     GPTRLNYARIVPMVDYTAQLVSRLVRK"
     gene            505085..505747
                     /locus_tag="HPDFL43_20452"
     CDS             505085..505747
                     /locus_tag="HPDFL43_20452"
                     /note="COG0576 Molecular chaperone GrpE (heat shock
                     protein)"
                     /codon_start=1
                     /transl_table=11
                     /product="probable heat shock protein"
                     /protein_id="ZP_02164908.1"
                     /db_xref="GI:163757819"
                     /translation="MRVNPIDIVFNRQDIHTMSDESQGREHDKPEADASVEADSPQEI
                     DPIAALTAEIEELKDQRLRMAAEMENLRRRTARDVKDAKSYAISGFARDMLQVSDNLE
                     RALAAVPEQADDATDNGLKTLIEGVELTGKAMLSALERHGVRKLEPKGQKFDPNFHQA
                     MFEVPNTEVPNNTVIEVVQPGYVIADRMLRPAMVGVAKGGPKDVPVSDAAQAYQDDGK
                     DD"
     gene            505801..506436
                     /locus_tag="HPDFL43_20457"
     CDS             505801..506436
                     /locus_tag="HPDFL43_20457"
                     /note="COG2860 Predicted membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane protein"
                     /protein_id="ZP_02164909.1"
                     /db_xref="GI:163757820"
                     /translation="MTPLEGLDYAGVAVFAATGALSASRKQLDLIGFGFLAAVTGIGG
                     GTIRDLILGDVPVFWVEKPAYLVVCVAVAAIVYFTVHLVESRYRLLIWLDAIGLAAFA
                     VMGAAKGLALTGSPIVAVVTGMMTATFGGILRDLLSGEPSVLMRPEIYVSAALLGSAF
                     FIAASLLGAPLIVGSGLGVIAAFALRGGAIRYGWAFSPYRSRAGRPPEDVL"
     gene            complement(506507..507499)
                     /locus_tag="HPDFL43_20462"
     CDS             complement(506507..507499)
                     /locus_tag="HPDFL43_20462"
                     /note="COG0524 Sugar kinases, ribokinase family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164910.1"
                     /db_xref="GI:163757821"
                     /translation="MSRFDVLCIGNAIVDIIARCDEAFLVDNSIIKGAMNLIDADRAE
                     LLYSRMGPAIEASGGSAGNTAAGVASFGSRSAYFGKVSADQLGKIFSHDIRALGVHFD
                     TKPLEGTPPTARSMIFVTPDGERSMNTYLGACVELGPEDIEADVVADAKITYFEGYLW
                     DPPRAKDAIRQCAEIAHKNGREMAMTLSDPFCVGRYRDEFLDLMRSGTIDIVFANADE
                     AKSLYETDNFEHAIAQLRKDCKIAAITRSEHGSVIIRGDERVDIDAIDIDEVVDTTGA
                     GDLYAAGFLHGYANGKPLDVCGKLGSLAAGLVIQQIGPRPLLSLKDAAEKSKLG"
     gene            complement(507603..510353)
                     /locus_tag="HPDFL43_20467"
     CDS             complement(507603..510353)
                     /locus_tag="HPDFL43_20467"
                     /note="COG0249 Mismatch repair ATPase (MutS family)"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein"
                     /protein_id="ZP_02164911.1"
                     /db_xref="GI:163757822"
                     /translation="MNAETPLPSSTLTTAQLATAESRATATPMMEQFIEIKAANPDSL
                     LFYRMGDFYELFFEDAIDASRALGITLTKRGQHLGQDIPMCGVPVHAADDYLQKLISL
                     GFRVAVCEQTEDPAEAKKRGSKSVVRRDVTRLVTPGTLTEEKLLDPSQSNFLMALARI
                     KGSGEAQFGLAWIDISTGAFHVAESRLARLLADIARVEPRELILAENVFHDPDIRPLV
                     DQLGRVATPQPGVLFDSATAEGRITRFYDLGSLDGFGSFSRAEMAAAAAVIAYVEKTQ
                     ISERPPLGRPERESDGARLFIDPATRASLELVRTLSGARQGSLIKAIDRSVTAGGGRK
                     LGEWLMAPLTDPAAINARLDGVSYLIGDSTLTDALRQALKGVADMPRALSRLALNRGG
                     PRDLGAILAGVRAAGEIANLFDGMEVPEHLAAAASCLRNLPKEIEARLSATLGDELPL
                     LKRDGGFVRTGASSELDELRALRDQSRRVIAGLQLSYAEETGVRSLKIKHNNVLGYFI
                     EVTALNAGPLTEGDEAKAKYIHRQTMANAMRFTTTELSDLETRIANAAGEALAIELAA
                     FDELVLLVVSQADAIKAAADALSVIDVTAALAELAQEQGYCRPKVDSSLAFEISAGRH
                     PVVEQALRRQAEQPFVANDCDLSPPEGSGDGGAIWLLTGPNMGGKSTFLRQNALIAVM
                     AQMGSFVPAGSAHIGVVDRLFSRVGASDDLARGRSTFMVEMVETAAILNQAGPHSLVI
                     LDEIGRGTATFDGLSIAWAAVEHLHAQNRCRALFATHFHELTALSEKLPRLSNATMKV
                     KEWEGDVVFLHEVGPGAADRSYGIQVARLAGLPDAVVVRAREVLDLLESSERENPAAR
                     LVDDLPLFAMPAVREPAKPAKGPSESDAYLGELNPDDMTPREALDALYELKRRLEPSG
                     KT"
     gene            510510..512795
                     /locus_tag="HPDFL43_20472"
     CDS             510510..512795
                     /locus_tag="HPDFL43_20472"
                     /note="COG0281 Malic enzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="ZP_02164912.1"
                     /db_xref="GI:163757823"
                     /translation="MPGTDKSDRSFSAVTDQEALDFHARGRPGKLEINPTKPMATQRD
                     LSLAYSPGVAVPVKAIAEDPSRAFDYTARGNMVAVISNGTAILGLGNLGALASKPVME
                     GKAVLFKRFADVDSIDLEVDTENVDEFVNCVRFLGPSFGGINLEDIKAPDCFIIEQRL
                     REIMDIPVFHDDQHGTAIIAVAGLINALHLTGRDLKTTRLVCNGAGAAAIACVELVKA
                     MGFAPENVTLCDTKGVIYKGRTEGMNQWKSAHAVETEARSLADAMEGADVVFGLSVKG
                     ALTEDMIRSMGDNPIIFAMANPDPEITPEEVAGIRDDAIMATGRSDYPNQVNNVLGFP
                     YIFRGALDVRATTINDSMKIAAAQALADLAREDVPDDVAAAYQGVRPRFGPQYIIPVP
                     FDPRLISAIPAAVAKAAMDSGVAQKPILNMDLYAHELSARRDPIASTLQRIYERVRRH
                     PRRVVFAEGEEEQVMRAAVSYVNQRLGTACLLGREEQMRETARLAGIDLDRPGIELVN
                     ARVSRRVEAYTDYLYSRLQRKGYLQRDCQRLINTDRNHFGACMVALGDADAMVTGITR
                     NYSTALEDVRRCIDVKPGHRMIGVSLALCRGRTVLVADTAVIDMPNAEELADIAEEAS
                     GMARRLGYEPRVAMLAYSTFGHPTGERSDRVREAVRILDKRRVDFEYDGEMAADVALN
                     ADVMEQYPFCRLSGTANVLVMPAFHSASISTKMLEELGGSTVIGPLLVGLDKSVQIVS
                     MGAKDSDIVNMAAIAAYNAAS"
     gene            complement(512907..513776)
                     /locus_tag="HPDFL43_20477"
     CDS             complement(512907..513776)
                     /locus_tag="HPDFL43_20477"
                     /note="COG3176 Putative hemolysin"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164913.1"
                     /db_xref="GI:163757824"
                     /translation="METQVQPPSATSISLPFTPGQSGTRTLGRIGSLEVRLATTRAEI
                     EAAQELRYKVFVEEMGARLPLEAMQQKRDFDTVDRYCDHLLVSDTALGGEPETQIVGT
                     YRLLRQDVAERHDGFYSQSEFDVADLVGRHRGKRFLELGRSCVLPAYRTRRTLEALWQ
                     GNWAYALEHRIDVMFGCASFSGDKPHAHALALSFLNETVAARDEWTVRAIPGRGLSMD
                     MMPVEAITPRAALSAMPPLVKGYLRLGALVSHEAVVDRAFRTTDVLVILPVKQISGRY
                     INHYGADASRFVA"
     gene            complement(513924..516290)
                     /locus_tag="HPDFL43_20482"
     CDS             complement(513924..516290)
                     /locus_tag="HPDFL43_20482"
                     /note="COG0642 Signal transduction histidine kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sensor histidine kinase transmembrane
                     protein"
                     /protein_id="ZP_02164914.1"
                     /db_xref="GI:163757825"
                     /translation="MSTEPHRLQSALSTALNQPAPYSNEVPPVAPAVRYPVPGAAPAS
                     HDETLRDSAPNALAGLSGALPLFLISGALGAAALSVAFDTPAALLASVAGISVVAAMP
                     LLKRPADPSSAADKPGRKPIKANMTPDPDRSKAEHDSDRTWELGEFTSHLTTLFDGLS
                     DMIAACDLEGRIIFANETFRLAIGTENPVGLTLAQAGVAPTQTDGTGQRELVLGEGEA
                     QSVWTWRETIARDPVSGKMFVHCVGRNVTATRKAEAELVEALERAEAASHAKTRFLAT
                     VSHEIRTPLNGILGMTHLLSQTETTPEQASYIRNARESGQSLLSLIEDLLDVTSIEAG
                     RLNLREEEGDLSELVHGVCELMASKAHEKNIEIAVHIAVDAPQRIASDIGRVRQILFN
                     LVGNAIKFTESGGVLVEVSLENAALVFSVTDTGPGLKETDKAKIFEEFERADNGPTRK
                     HGGAGLGLSISARIVEALGGEIGVDSTPGKGSKFHFSVPIADISNSAQVTALRGPLSD
                     RAVLVIAPRGPVSAAMLWSIRDLGGYAEAASDAESMLAALSRLNRTGLMLSDIIVDRR
                     IADQAESLLASAPTVLSDKIARTLVIAPEDSRDLEGHGDHGADAWLVRPVRRTSLINV
                     LTRRDDRDDRNRLASKPRPPVLERTSDNPTLDILLAEDDPVNALMVRTMLARQGHRIT
                     LVENGRALVEEAMNRPGGKMNYDLVITDLSMPELDGRSAIARIRADEDVNQLDHLPII
                     VLSADGQASTRDDILAAGADGHAEKPVDPEWLISLVAMTARKRSATAG"
     gene            complement(516363..517358)
                     /locus_tag="HPDFL43_20487"
     CDS             complement(516363..517358)
                     /locus_tag="HPDFL43_20487"
                     /note="COG0604 NADPH:quinone reductase and related
                     Zn-dependent oxidoreductases"
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase (zinc-binding alcohol
                     dehydrogenase, NADPH quinone oxidoreductase,
                     oxidoreductase)"
                     /protein_id="ZP_02164915.1"
                     /db_xref="GI:163757826"
                     /translation="MDNRFKGIQLTRDENKVMSVNVAELGLDDLMEGDVVVEVEWTTV
                     NYKDGLAITGKGPVVRRWPMVPGIDCAGTVVSSENARFSPGDKVILNGFGVGETHTGA
                     FAAYARLNGDWLIPMPNGMDGRSSMAIGTAGYTAMLSVMALERHGITPERGPVVVTGA
                     NGGVGTVAIAVLGKLGYEVIASTGRTEEADFLKELGASDVIHRDELSGPAKPLNKERW
                     AGGIDAVGSHTLANVLSMTSYGGAVAACGLAQGMDLPSSVAPFILRGVSLLGIDSVMA
                     PLALRQEAWARLVTDLDMAKLEALSTEIGFDGIIDAAHSIVDGKIRGRVVVDMKH"
     gene            complement(517431..517934)
                     /locus_tag="HPDFL43_20492"
     CDS             complement(517431..517934)
                     /locus_tag="HPDFL43_20492"
                     /note="COG0597 Lipoprotein signal peptidase"
                     /codon_start=1
                     /transl_table=11
                     /product="probable lipoprotein signal peptidase
                     transmembrane"
                     /protein_id="ZP_02164916.1"
                     /db_xref="GI:163757827"
                     /translation="MSGASLSRMGPMLTMVTGAVALDQVIKYLVETRLPFHELIPVMP
                     MLGLFRTWNEGIAFSLLKDLPDTGLLMLTAMVIVFVIFLWWRTPSDRSIAHLGFALII
                     GGALGNLVDRAIYGHVVDYILFYTSTWSFAVFNLADSFISIGAGLIVLDEVIAALRER
                     KAKKQSD"
     gene            complement(517931..518794)
                     /locus_tag="HPDFL43_20497"
     CDS             complement(517931..518794)
                     /locus_tag="HPDFL43_20497"
                     /note="COG0566 rRNA methylases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative trna/rrna methyltransferase protein"
                     /protein_id="ZP_02164917.1"
                     /db_xref="GI:163757828"
                     /translation="MTDKPSSTGPGRVGQVKEITSLSNPVIKDIRALSMKKHRDETGS
                     FLAEGLKLVIDAIDQGWNIRTLIYAKAQRGKPQVEKIAALTVARGGLVLEVSEKVLTA
                     ITRRDNPQAVIAVFEQKLTPLDAVAPKPDETWIALDRVRDPGNLGTIIRTADAAGASG
                     VILIGDTVDPFSTETVRATMGSIFAMPLLRASEAEFLTWSKKTAPLVVGSHLKGSVDY
                     RTIAYKGRPVVLLMGNEQAGLPDTLAQSCGKLARIPQTGRADSLNLAIATGVMLFEAR
                     RHLLSLEADAQ"
     gene            complement(518791..520065)
                     /locus_tag="HPDFL43_20502"
     CDS             complement(518791..520065)
                     /locus_tag="HPDFL43_20502"
                     /note="COG0532 Translation initiation factor 2 (IF-2;
                     GTPase)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164918.1"
                     /db_xref="GI:163757829"
                     /translation="MADKRSQQPRRGGRPTAKSAGTGRDASKGPSKGQPKATSKGKPR
                     PGSAAGGQPTFKPGQGARKGKPSFSKSGALSQSGAPLRADARSAEAGAQARRSANATP
                     TQAPIRALTGRSGALPRENAPLILEIGDEHGYRLIDSGRNADGVGEKLELYGDLRVIR
                     PEAQALWPRGLPDADWAKADALFTGDTDEDGIGRWAFPNAPLGETWPMQLLGVDFFGR
                     LTSFRHVGVFPEQIAHWRWMADQITQAKRPLKVLNLFGYTGVASLVAAKAGAEVTHVD
                     ASKKAIGWARENQALAGLEDRPVRWICEDAMKFIAREERRGSRYDIILTDPPKFGRGP
                     NGEVWQLFDHLPLMLDICRELLSPKPVGLVLTAYSIRASFYAIHELMRETMRGAGGVV
                     ESGELILRESGKPDPAACRALSTSLYSRWLPA"
     gene            520245..520700
                     /locus_tag="HPDFL43_20507"
     CDS             520245..520700
                     /locus_tag="HPDFL43_20507"
                     /note="COG3427 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164919.1"
                     /db_xref="GI:163757830"
                     /translation="MEMHGEERIAAPRQLVWEALNDPDVLRECIPGCQSLEKSSDTEM
                     SATVKVKIGPVSAKFSGEVTLENINAPESYTISGEGKGGIAGFANGGADVKLVEEGAE
                     TVLSYEVKAQVGGKIAQLGSRLIDSTSKKLAGQFFTRFNEVVSEKAAQA"
     gene            complement(520744..521094)
                     /locus_tag="HPDFL43_20512"
     CDS             complement(520744..521094)
                     /locus_tag="HPDFL43_20512"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane protein"
                     /protein_id="ZP_02164920.1"
                     /db_xref="GI:163757831"
                     /translation="MIKRIVALAILLPTAIVLIMLSVANRTAVTLALNPFQPSDQVLS
                     VTAPFFVFLFATLMLGMIIGSLATWFKQGKHRKQARANASEAVKWHTEADRHKAKAEQ
                     IAAALPAPDKRNAA"
     gene            complement(521227..521517)
                     /locus_tag="HPDFL43_20517"
     CDS             complement(521227..521517)
                     /locus_tag="HPDFL43_20517"
                     /note="COG0776 Bacterial nucleoid DNA-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative integration host factor beta subunit"
                     /protein_id="ZP_02164921.1"
                     /db_xref="GI:163757832"
                     /translation="MIKSELVQAVAARNPHLYHRDVENIVNAVLDEITDALSQGTRVE
                     LRGFGAFSVKNRPPRSGRNPRTGEPVFVEEKWVPFFKTGKELRERLNPDDKD"
     gene            complement(521528..522496)
                     /locus_tag="HPDFL43_20522"
     CDS             complement(521528..522496)
                     /locus_tag="HPDFL43_20522"
                     /note="COG0616 Periplasmic serine proteases (ClpP class)"
                     /codon_start=1
                     /transl_table=11
                     /product="proteinase IV protein"
                     /protein_id="ZP_02164922.1"
                     /db_xref="GI:163757833"
                     /translation="MTDPNVLADRRRLRRKLGFWRIFAVVAVIAVVAALAFNLDGPDT
                     GSDHIARIDISGVISDDEDLIDLIEDAASSETAKALVVRISSPGGTTYGGERIYKALL
                     EAGKSKPVVADVRTLAASAGYMIAASSDHIVAGESSIVGSIGVIFQYAQAQELLNKIG
                     LRIEEIKSAPLKAEPSPFHDTSEEAKAMIRAMVLDSYDWFVDLVTERRGMTRADVLAL
                     ADGSIFTGRQALGNGLVDAIGGEAEIRAYLESRDVEADLEIIEWEKQSDPARRLIGAQ
                     AVDLIASYFGVPMRLSDEIDRLSGGKLFLDGLVSVWQVGGKQAADN"
     gene            522687..523367
                     /locus_tag="HPDFL43_20527"
     CDS             522687..523367
                     /locus_tag="HPDFL43_20527"
                     /note="COG5375 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164923.1"
                     /db_xref="GI:163757834"
                     /translation="MTTTSVSEIPRTGAYAGRSHAEYRRAQTHSRRVRALKILLPLAS
                     VLVVIGFVAVSFVDTLVPEGVAIESVAVRDGKLVMQNPVMSGQTSDARSYRLEALRAI
                     QDLATPDVIVLEDILAELPVSAGETAVLEATSATFDRGAQTLVFREPFKVQSEGGFSA
                     EMQSADIDMATSEMSTSDPVTIRSGEASVVAKSMKMQDKGRLIILENQVRMTINPSAI
                     KQPARESN"
     gene            523369..523920
                     /locus_tag="HPDFL43_20532"
     CDS             523369..523920
                     /locus_tag="HPDFL43_20532"
                     /note="COG1934 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164924.1"
                     /db_xref="GI:163757835"
                     /translation="MAKTSLPIVGLAALLGVAVLAGPQPVQAQTSESRMTGLALSGDE
                     PIQIESDLLQINEETSQATFTGNVRVLQGDTVLQAGEMIVHYAKNGGSVASGAADIRE
                     IDLFKKVLIRSGTQTATADTGNFNMANEVLVLSGEKVVLTDAENVFIGCKLTVQMQNG
                     QAKLDSCGRRVMIQLDPKSRSKQ"
     gene            523917..524723
                     /locus_tag="HPDFL43_20537"
     CDS             523917..524723
                     /locus_tag="HPDFL43_20537"
                     /note="COG1137 ABC-type (unclassified) transport system,
                     ATPase component"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter related protein"
                     /protein_id="ZP_02164925.1"
                     /db_xref="GI:163757836"
                     /translation="MIRALFSSLGNRGGKGDADVAEDGVGRYDGTLIARNLTKAYKSR
                     RVVDGVSLGVRRGEAVGLLGPNGAGKTTCFYMITGLVPVDSGTIEIDGHDVSDLPMYR
                     RARLGVGYLPQEASIFRGLSVEANIRAVLEVVEKNRALREEKLDSLLSEFHISHLRKS
                     ASISLSGGERRRLEIARALASDPTFMLLDEPFAGVDPIAVSDIQDLVRHLTRRGIGVL
                     ITDHNVRETLGLIDRAYIMNAGVLLTHGRPSEIVANPDVRRLYLGEQFSL"
     gene            524967..526553
                     /locus_tag="HPDFL43_20542"
     CDS             524967..526553
                     /locus_tag="HPDFL43_20542"
                     /note="COG1508 DNA-directed RNA polymerase specialized
                     sigma subunit, sigma54 homolog"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor protein (sigma-54)"
                     /protein_id="ZP_02164926.1"
                     /db_xref="GI:163757837"
                     /translation="MALSASLQLRQSQSLVMTPQLMQSIRLLQFSHIELNRFIEQEVE
                     RNPLLELVTPESEANNEGANGDGSETSRDHSAQDSQSGASSSEGGEGADGLWAASSET
                     STERLNEEIDGRYENVFPDDHGVEKPSAPEFVDNWKSMPGNDGGQGGEGYDLDDFAAR
                     APTLRDHVAEQIAFTFADPAERLIATDIADQLDAAGYIAGDLLETIERLSIDQAKLEH
                     VLGRLQEFEPAGLFARSLSECLALQLDRKNRLDPAMAALVNNLELLARRDFSTLKRLC
                     GVDEEDLLDMLAEIRALDPKPGTRFETGSSELIVPDVSVKPGADGGWVVELNSETLPR
                     VLVNQSYFATVSSQMAKNTPGQEFLSECMQTANWLVRSLDQRARTITKVASEIVRQQD
                     AFLLHGVDHLRPLNLKAVADAIGMHESTVSRVTSNKYMITPRGVFELKYFFTVSIASA
                     EAGGDAHSAESVRHRIKALIDEELPDSVLSDDDLVTLLKQSGVEIARRTVAKYREAMS
                     IPSSVQRRREKRARARAAAV"
     gene            526828..527373
                     /locus_tag="HPDFL43_20547"
     CDS             526828..527373
                     /locus_tag="HPDFL43_20547"
                     /note="COG1544 Ribosome-associated protein Y (PSrp-1)"
                     /codon_start=1
                     /transl_table=11
                     /product="probable sigma54 modulation protein"
                     /protein_id="ZP_02164927.1"
                     /db_xref="GI:163757838"
                     /translation="MEIGESFRTRIDDHVSGAVRKYFDGGFSSHVTVEKSGSRFQADC
                     KIHLDTGVVLHATGEAQDPQPAFDAAAERIEKRLRRYKRRLKDHHANSQPSQAELAYA
                     VVGSGDEDADEVPEDYAPAIIAESTKQLVTMSVANAVMALDMTDERILMFRNAGNDAL
                     NVVYRRNDGNIGWIDAGGVKS"
     gene            527497..527961
                     /locus_tag="HPDFL43_20552"
     CDS             527497..527961
                     /locus_tag="HPDFL43_20552"
                     /note="COG1762 Phosphotransferase system
                     mannitol/fructose-specific IIA domain (Ntr-type)"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-N(pi)-phosphohistidine-sugar
                     phosphotransferase protein (enzyme II of
                     thephosphotransferase system)"
                     /protein_id="ZP_02164928.1"
                     /db_xref="GI:163757839"
                     /translation="MALADLIAQNSVLPALKANSKKQLLQELAAKASEVTGLAEREVF
                     DVILQRERLGSTGVGNGIAIPHGKLPSLDRIIGVFARLDQPVDFEALDDQPVDLVFLL
                     LAPEGAGADHLKALSRIARVMRDSEMVAKLRATDDAASLYAFLAEEPESNAA"
     gene            complement(527984..528241)
                     /locus_tag="HPDFL43_20557"
     CDS             complement(527984..528241)
                     /locus_tag="HPDFL43_20557"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164929.1"
                     /db_xref="GI:163757840"
                     /translation="MIAKSGKTQLSAQDLALLGAGKVGYIRKMRSEDVLAKFPEAPEL
                     DPGVELWALFGADGTPILLTDNRSSTFYRAAEDELKTVCLH"
     gene            complement(528297..528728)
                     /locus_tag="HPDFL43_20562"
     CDS             complement(528297..528728)
                     /locus_tag="HPDFL43_20562"
                     /note="COG0071 Molecular chaperone (small heat shock
                     protein)"
                     /codon_start=1
                     /transl_table=11
                     /product="probable small heat shock protein"
                     /protein_id="ZP_02164930.1"
                     /db_xref="GI:163757841"
                     /translation="MSRMTPFSSPLLLGFDTMEKTLERIAKGSEGYPPYNIERIRASA
                     DGSNADRLRITLAVAGFCEEDLDVTTEENQLVIRGRQAEVEGREYLHRGIAARQFQRM
                     FVLADGMQVVGAELKNGLLSVDLIRPEPERMVRKINISVRD"
     gene            528889..529827
                     /locus_tag="HPDFL43_20567"
     CDS             528889..529827
                     /locus_tag="HPDFL43_20567"
                     /note="COG1957 Inosine-uridine nucleoside N-ribohydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="inosine-uridine preferring nucleoside hydrolase
                     protein"
                     /protein_id="ZP_02164931.1"
                     /db_xref="GI:163757842"
                     /translation="MTPRKIIIDTDPGQDDAAAIMLAFASPELEVLGITAVAGNVPLS
                     RTALNARIVAEISGRSDIPVYAGAEAPLKRKLVTAEHVHGKTGLDGVDIFEPARPLEQ
                     AHAVDFIIETLRTNPEKTITLCPLGPLTNIAMAFERAPDTIARVAQIVLMGGGFFEGG
                     NITPAAEFNIYVDPESAKIVFAAGVPITMMPLDVTHKVLTTRTRVDRLRANGNRASLE
                     MASMLEFFERYDEQKYGTDGGPLHDPTVIAWLIDPEMFTGRNCNVEIETGSELTLGAT
                     VVDWWKVTGRKENALVIGDVDADRFFDLFIERLGRL"
     gene            complement(529834..530769)
                     /locus_tag="HPDFL43_20572"
     CDS             complement(529834..530769)
                     /locus_tag="HPDFL43_20572"
                     /note="COG0524 Sugar kinases, ribokinase family"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose kinase protein"
                     /protein_id="ZP_02164932.1"
                     /db_xref="GI:163757843"
                     /translation="MRPAAVSKRESAMITVIGSINMDLIGTTARLPAPGETVSGSDFT
                     TAPGGKGANQALAARRAGASTKMVGATGNDAFAAEALALLEAAGTDLGGVRGLEGATG
                     IALILVGGDGENVIVVIPGANGQVSAQDASDAVAAMSSGDTVLLQMEIPEAAVRAALE
                     ASRARGVRSILNIAPLTDAVERLAPLADIVIANETEFARLSGRPVEALAEVKAELEAL
                     HDRSGQCLIITLGGDGVLWARDGRSGHVPSLKIAPVDTVGAGDTFCGYLAQGLDAGMA
                     FEEAVRRAAAAGALACLTPGAQPSIPLAEDVDARL"
     gene            complement(530814..532100)
                     /locus_tag="HPDFL43_20577"
     CDS             complement(530814..532100)
                     /locus_tag="HPDFL43_20577"
                     /note="COG1322 Uncharacterized protein conserved in
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA recombination protein"
                     /protein_id="ZP_02164933.1"
                     /db_xref="GI:163757844"
                     /translation="MENPANPFLTPVFELNGLAITLGQSLFGLAIAVLLLVVWLTLAL
                     GRSNRARAQINAEAAARAAQAEARLAEILKAQAEMQGRMGTMAEVFGARQAELNQAIG
                     QRLDGMTQRIGSTLTDQTRATHENLARLQERLAAIDTAQSNIQSLARDVVGLQAILSN
                     KQTRGAFGQSRMETIVQDGLPMGAFRFQPTLSNGTRPDCTVKMPNGAPDLVIDAKFPL
                     EAWNAMREAQAEALGEQAFQAAQQRFRRDMEVHIRDISEKYLIAGETQDTAFLFVPSE
                     SIFAEIHETLEAIVQRAHRARVVIVSPSLLMLSIQVIQAILKDARMREQAHLIQGEVV
                     RLMEDLSRLDDRTRKLQAHFSMAQKDVDLILTSSDKLTKRGSRIEALEFAQLKNDAEQ
                     TDSPQTEQQAPPTPDPAPKFEPRSSTLKLRVVDEDD"
     gene            532226..532744
                     /gene="def"
                     /locus_tag="HPDFL43_20582"
     CDS             532226..532744
                     /gene="def"
                     /locus_tag="HPDFL43_20582"
                     /EC_number="3.5.1.88"
                     /note="COG0242 N-formylmethionyl-tRNA deformylase"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="ZP_02164934.1"
                     /db_xref="GI:163757845"
                     /translation="MTIKPLVLLPDPILRQQSLPVERVDAELEGFIDDMLETMYDAPG
                     IGLAAIQVGVPRRLLVIDVAGKDEPKSPQVFINPEVVATGDGISVYEEGCLSIPDYYA
                     DVERPETITVKYLGRDGKEHTTEADGLLATCLQHEIDHLNGVLFIDHISKLKRDMVVR
                     KFTKLAKQRMTA"
     gene            532866..533810
                     /locus_tag="HPDFL43_20587"
     CDS             532866..533810
                     /locus_tag="HPDFL43_20587"
                     /note="COG0223 Methionyl-tRNA formyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="ZP_02164935.1"
                     /db_xref="GI:163757846"
                     /translation="MPLRIIFMGTPAYAVPTLQALHEAGHEIVAVYSQPPRPAGRRGL
                     ELKPSPVHEAAEGLGIPVFTPKSLKSDEEQAAFKALEADAAVVVAYGLLLPKPVLDAP
                     RLGAWNGHASLLPRWRGAAPIQRAIMAGDTTTGVMIMQMDVGLDTGPVALTQTVDISA
                     SMTTGELHDTLAGVTAKLMTDAMARLERGELPVRVQPEQGVSYAAKISKEETRVDFTR
                     TALDVHNHIRGLAPAPGAWFELQTGDRAERVKLLASGVVAGGAQGEVPGTVLDEQLTI
                     ACGEGAVRLLRLQKAGGKPLSAQDFLRGTPVAPGAVIG"
     gene            533810..534577
                     /gene="truA"
                     /locus_tag="HPDFL43_20592"
     CDS             533810..534577
                     /gene="truA"
                     /locus_tag="HPDFL43_20592"
                     /EC_number="5.4.99.12"
                     /note="COG0101 Pseudouridylate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine synthase A"
                     /protein_id="ZP_02164936.1"
                     /db_xref="GI:163757847"
                     /translation="MPRYRLDIEYDGSGYAGWQRQDDHPSIQQAIETAIHGFCGQAVS
                     IRGAGRTDAGVHAWGQVAHVDLENQWSDDTVRDAINAHLQMARERVAILAAREVPEDF
                     DARFSATRRHYVYRIICRRAPLVIEKNRALWSPRPLDAEAMHEAAQRLVGRHDFTTFR
                     SVQCQADSPVRSLDRLDVTRGGFDGLIEIHATARSFLHNQIRSFAGTLRLVGEGKWTA
                     DDVQIALEARSRKACGPVAAPEGLYFRQVDYDGLFPV"
     gene            534924..535079
                     /locus_tag="HPDFL43_20597"
     CDS             534924..535079
                     /locus_tag="HPDFL43_20597"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164937.1"
                     /db_xref="GI:163757848"
                     /translation="MRDKLKSSAPVLYGRLVYASAASNMVKPVARTLDVAIAETNTGS
                     QDNWEKF"
     gene            535079..535549
                     /locus_tag="HPDFL43_20602"
     CDS             535079..535549
                     /locus_tag="HPDFL43_20602"
                     /note="COG0835 Chemotaxis signal transduction protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative chemotaxis protein"
                     /protein_id="ZP_02164938.1"
                     /db_xref="GI:163757849"
                     /translation="MQENTNNAAQSGYLEIISFHLGEQVFCVNIMAVREIRGWAPSTT
                     LPHTPPHVLGVINLRGSVIPVIDMAIRLGLKPIEPTERSAIIVTNIAGKLVGLLVENV
                     SDMITVNESELQPAPDVLPAAERALTKAIIPVDKQMICYLDLDTLFADTEDEAA"
     gene            complement(535695..536300)
                     /locus_tag="HPDFL43_20607"
     CDS             complement(535695..536300)
                     /locus_tag="HPDFL43_20607"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164939.1"
                     /db_xref="GI:163757850"
                     /translation="MAAGLIPSRAEAGRSIAGLFYLSLKRPEGLKLFDVSSDGFWRSF
                     GAFAWAWPVQCFLWTGMWRASPDTRPESAGDYLGFFLTSTAFDVAAWVLPAIMLLAVT
                     QLFGMADKFTRLVVVNNWFGLFSAYIGFFPAALRYLAPVPDGLSAIISLAVYVIVIGL
                     YYRVTRIAVGGETMIAVFITALMVVSGLTISEFAFTALSGE"
     gene            complement(536303..537499)
                     /locus_tag="HPDFL43_20612"
     CDS             complement(536303..537499)
                     /locus_tag="HPDFL43_20612"
                     /note="COG0624 Acetylornithine
                     deacetylase/Succinyl-diaminopimelate desuccinylase and
                     related deacylases"
                     /codon_start=1
                     /transl_table=11
                     /product="putative succinyl-diaminopimelate desuccinylase"
                     /protein_id="ZP_02164940.1"
                     /db_xref="GI:163757851"
                     /translation="MKLTDPTQTLTALIRCPSVTPEEGGALTELAGMLSELGFANDRV
                     TFSDEGTPDVENLYSRLGSEGPHLMFAGHTDVVPVGDAEAWTQGPFSADIVDGEMYGR
                     GAVDMKGGIACFVSALARLIERKGPLKGSVSLLITGDEEGPSINGTEKLLVHAAGKGE
                     RWDAAVVGEPTNPDQLGDMIKIGRRGSLSGTLTVEGVQGHVAYPHLADNPLPGMMALA
                     SALIDPPLDAGNERFPPSNLEITSIDTGNTATNVIPARCTAKFNIRFNDQWTAESLKA
                     ELRARIEQASGGGSSRTGQEKVRYTVKFADRPSSSFLTHDAPLIEALSNAVTEATGRT
                     PALSTTGGTSDARFIKDYCPVVEFGLVGKTMHMVDERVAVSDLEALTGIYELFLERWF
                     DRAGAH"
     gene            complement(537563..537919)
                     /locus_tag="HPDFL43_20617"
     CDS             complement(537563..537919)
                     /locus_tag="HPDFL43_20617"
                     /note="COG3152 Predicted membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164941.1"
                     /db_xref="GI:163757852"
                     /translation="MRWLLFSVSGRLSRRTYAWALLFWTLSLSITVSAAANAPDDSTS
                     LALAGLGFILVCVTGAWSIAVMSIKRLHDAGLPGMLVIGLVIPAASFLVLLVIMFWRS
                     DKGPNRHGPGSDQPGY"
     gene            complement(537950..538792)
                     /gene="dapD"
                     /locus_tag="HPDFL43_20622"
     CDS             complement(537950..538792)
                     /gene="dapD"
                     /locus_tag="HPDFL43_20622"
                     /EC_number="2.3.1.117"
                     /note="COG2171 Tetrahydrodipicolinate
                     N-succinyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2-carboxylate
                     N-succinyltransferase"
                     /protein_id="ZP_02164942.1"
                     /db_xref="GI:163757853"
                     /translation="MAALASTIETAFDNRDSVSVSTRGEVREAVDEALNLLDRGEARV
                     AVRGDDGTWTVNQWLKKAVLLSFRLNPMEIIKGGPGDAVWWDKVPSKFEGWSANEFER
                     SGFRAVPGSIVRRGSFIGKNVVLMPSFVNLGAYVDEGSMVDGWATVGSCAQIGKNVHL
                     SGGVGIGGVLEPLQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVYIGKSTRIVN
                     RMTGEIGYGEVPPYSVVVAGSMPSSGTMGNGATAPNLYCAVIVKTVDAQTRSKTGINE
                     LLRD"
     gene            538953..539795
                     /locus_tag="HPDFL43_20627"
     CDS             538953..539795
                     /locus_tag="HPDFL43_20627"
                     /note="COG1611 Predicted Rossmann fold nucleotide-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lysine decarboxylase family protein"
                     /protein_id="ZP_02164943.1"
                     /db_xref="GI:163757854"
                     /translation="MNADRTDQIWDPLSDSREDRRRAERQPKTPQSTSPSYRLAYADD
                     DFLCRDELRPVRLQLELLKPEMILTEAGIRSTVVMFGGARIPEPGKAPWAAKNETQAK
                     NLTAAAKYYEEARSFARLCSTHSQSKEAREFVVVTGGGPGVMEAGNRGAHDVGAKSIG
                     LNVVLPHEQAPNAYVTPELSLNFHYFAIRKMHFLMRAKAITIFPGGFGTLDELFESLT
                     LIQTKRMEHVPLILFGSEFWNSIVDFQALADFGTIAPEDLDLLRFVDTADEAWAIIER
                     HYGL"
     gene            complement(539890..540480)
                     /locus_tag="HPDFL43_20632"
     CDS             complement(539890..540480)
                     /locus_tag="HPDFL43_20632"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164944.1"
                     /db_xref="GI:163757855"
                     /translation="MKKTLLTTLAAIMAASVAVPAIAAQQSKGHHGGPRIERIIERFD
                     ANGNGAIEREEISAHRTAMFNSVDADQSGTLSEDELAALAEVRRAERDQAREEMRAER
                     KKEREERRAERHGKRGEGKMGREHAGRGDGKRGEGRGMGRHGGPSIERLDADNNGEVS
                     AEEFAAVETRMFERFDRNGDDKIDVTDFYRNKAGKN"
     gene            complement(540618..541313)
                     /locus_tag="HPDFL43_20637"
     CDS             complement(540618..541313)
                     /locus_tag="HPDFL43_20637"
                     /note="COG1011 Predicted hydrolase (HAD superfamily)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164945.1"
                     /db_xref="GI:163757856"
                     /translation="MTLPAAADFAHVTEWVFDLDNTLYPRHTDLFSQIDKKMTQFVRE
                     LLDLEHDAARALQKKYYREHGTTLQGLMLHHGIDPNDFLEKVHDIDYSWVKPDPELGN
                     AIRALPGRKFIFTNGDTPHAERTAAALGILDHFDEIFDIVAADLKPKPAPETYDRFLA
                     RHGVHSDRAAMFEDLPRNLVAPHQLGMRTVLIVPRNIDVVLDEVWEHEGKDGAHIHHI
                     TDDLTAFLKAATA"
     gene            541483..541866
                     /locus_tag="HPDFL43_20642"
     CDS             541483..541866
                     /locus_tag="HPDFL43_20642"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ZP_02164946.1"
                     /db_xref="GI:163757857"
                     /translation="MSLDGAQASRIGKVAKVAAAAVSVSLLSTAAFLLWLEGGLTLRP
                     LVAASICALVLTVPVTLFILDQVDKLHRADADLAEARRQLFAIHLELQQAQQTVESEQ
                     LAGEVECETPAPADAPIARPLQGFA"
     gene            541951..542994
                     /locus_tag="HPDFL43_20647"
     CDS             541951..542994
                     /locus_tag